NBR 1‐mediated p62‐liquid droplets enhance the Keap1‐Nrf2 system

The selective autophagy receptors Optineurin and p62 are both required for zebrafish host resistance to mycobacterial infection

(2019) Rui Zhang et al.   PLoS Pathogens

FIP200 Claw Domain Binding to p62 Promotes Autophagosome Formation at Ubiquitin Condensates

(2019) Eleonora Turco et al.   MOLECULAR CELL

Polyubiquitin chain-induced p62 phase separation drives autophagic cargo segregation

(2018) Daxiao Sun et al.   CELL RESEARCH

p62 filaments capture and present ubiquitinated cargos for autophagy

(2018) Gabriele Zaffagnini et al.   EMBO JOURNAL

Starvation induces rapid degradation of selective autophagy receptors by endosomal microautophagy

(2018) Jakob Mejlvang et al.   JOURNAL OF CELL BIOLOGY

What lava lamps and vinaigrette can teach us about cell biology

(2018) Elie Dolgin   NATURE

A brief history of autophagy from cell biology to physiology and disease

(2018) Noboru Mizushima   NATURE CELL BIOLOGY

Cargo recognition and degradation by selective autophagy

(2018) Damián Gatica et al.   NATURE CELL BIOLOGY

Mechanism and medical implications of mammalian autophagy

(2018) Ivan Dikic et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Nrf2 mediates the expression of BAG3 and autophagy cargo adaptor proteins and tau clearance in an age-dependent manner

(2018) Maoping Tang et al.   NEUROBIOLOGY OF AGING

Protein Phase Separation: A New Phase in Cell Biology

(2018) Steven Boeynaems et al.   TRENDS IN CELL BIOLOGY

p62/ SQSTM 1: ‘Jack of all trades’ in health and cancer

(2018) Pablo Sánchez‐Martín et al.   FEBS Journal

p62/SQSTM1 – steering the cell through health and disease

(2018) Pablo Sánchez-Martín et al.   JOURNAL OF CELL SCIENCE

Stress-sensing mechanisms and the physiological roles of the Keap1–Nrf2 system during cellular stress

(2017) Takafumi Suzuki et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Arsenic Induces p62 Expression to Form a Positive Feedback Loop with Nrf2 in Human Epidermal Keratinocytes: Implications for Preventing Arsenic-Induced Skin Cancer

(2017) Palak Shah et al.   MOLECULES

Biomolecular condensates: organizers of cellular biochemistry

(2017) Salman F. Banani et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

(2016) Daniel J Klionsky et al.   Autophagy

p62 in Cancer: Signaling Adaptor Beyond Autophagy

(2016) Jorge Moscat et al.   CELL

Parkin promotes proteasomal degradation of p62: implication of selective vulnerability of neuronal cells in the pathogenesis of Parkinson’s disease

(2016) Pingping Song et al.   Protein & Cell

p62/Sequestosome-1 Is Indispensable for Maturation and Stabilization of Mallory-Denk Bodies

(2016) Pooja Lahiri et al.   PLoS One

Sqstm1-GFP knock-in mice reveal dynamic actions of Sqstm1 during autophagy and under stress conditions in living cells

(2015) A. Eino et al.   JOURNAL OF CELL SCIENCE

Phosphorylation-mediated RNA/peptide complex coacervation as a model for intracellular liquid organelles

(2015) William M. Aumiller et al.   Nature Chemistry

Autophagy at the crossroads of catabolism and anabolism

(2015) Jasvinder Kaur et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Dominant-negative function of the C-terminal fragments of NBR1 and SQSTM1 generated during enteroviral infection

(2014) J Shi et al.   CELL DEATH AND DIFFERENTIATION

BRCA1 and Oxidative Stress

(2014) Yong Yi et al.   Cancers

Eukaryotic Stress Granules Are Cleared by Autophagy and Cdc48/VCP Function

(2013) J. Ross Buchan et al.   CELL

Dual Specificity Kinase DYRK3 Couples Stress Granule Condensation/Dissolution to mTORC1 Signaling

(2013) Frank Wippich et al.   CELL

BRCA1 interacts with Nrf2 to regulate antioxidant signaling and cell survival

(2013) Chiara Gorrini et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Deficiency of p62/Sequestosome 1 Causes Hyperphagia Due to Leptin Resistance in the Brain

(2013) H. Harada et al.   JOURNAL OF NEUROSCIENCE

Phosphorylation of p62 Activates the Keap1-Nrf2 Pathway during Selective Autophagy

(2013) Yoshinobu Ichimura et al.   MOLECULAR CELL

Impairment of autophagy: From hereditary disorder to drug intoxication

(2013) Toshihiko Aki et al.   TOXICOLOGY

Autophagic adapter protein NBR1 is localized in Lewy bodies and glial cytoplasmic inclusions and is involved in aggregate formation in α-synucleinopathy

(2012) Saori Odagiri et al.   ACTA NEUROPATHOLOGICA

KrasG12D-Induced IKK2/β/NF-κB Activation by IL-1α and p62 Feedforward Loops Is Required for Development of Pancreatic Ductal Adenocarcinoma

(2012) Jianhua Ling et al.   CANCER CELL

Adipose Deficiency of Nrf2 in ob/ob Mice Results in Severe Metabolic Syndrome

(2012) P. Xue et al.   DIABETES

NBR1 acts as an autophagy receptor for peroxisomes

(2012) E. Deosaran et al.   JOURNAL OF CELL SCIENCE

Mechanisms of BRCA1 Tumor Suppression: Figure 1.

(2012) Daniel P. Silver et al.   Cancer Discovery

The ubiquitin-binding adaptor proteins p62/SQSTM1 and NDP52 are recruited independently to bacteria-associated microdomains to target Salmonella to the autophagy pathway

(2011) Marija Cemma et al.   Autophagy

Autophagy: Renovation of Cells and Tissues

(2011) Noboru Mizushima et al.   CELL

NBR1 and p62 as cargo receptors for selective autophagy of ubiquitinated targets

(2011) Trond Lamark et al.   CELL CYCLE

Serine 403 Phosphorylation of p62/SQSTM1 Regulates Selective Autophagic Clearance of Ubiquitinated Proteins

(2011) Gen Matsumoto et al.   MOLECULAR CELL

TFEB Links Autophagy to Lysosomal Biogenesis

(2011) C. Settembre et al.   SCIENCE

p62/SQSTM1Is a Target Gene for Transcription Factor NRF2 and Creates a Positive Feedback Loop by Inducing Antioxidant Response Element-driven Gene Transcription

(2010) Ashish Jain et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The selective autophagy substrate p62 activates the stress responsive transcription factor Nrf2 through inactivation of Keap1

(2010) Masaaki Komatsu et al.   NATURE CELL BIOLOGY

NBR1 co-operates with p62 in selective autophagy of ubiquitinated targets

(2009) Vladimir Kirkin et al.   Autophagy

SEPA-1 Mediates the Specific Recognition and Degradation of P Granule Components by Autophagy in C. elegans

(2009) Yuxia Zhang et al.   CELL

A Role for NBR1 in Autophagosomal Degradation of Ubiquitinated Substrates

(2009) Vladimir Kirkin et al.   MOLECULAR CELL

The CCAAT-binding complex coordinates the oxidative stress response in eukaryotes

(2009) Marcel Thön et al.   NUCLEIC ACIDS RESEARCH

The CREB/CRE transcriptional pathway: protection against oxidative stress-mediated neuronal cell death

(2008) Boyoung Lee et al.   JOURNAL OF NEUROCHEMISTRY