Drug repurposing towards targeting cancer stem cells in pediatric brain tumors
Published 2020 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Drug repurposing towards targeting cancer stem cells in pediatric brain tumors
Authors
Keywords
-
Journal
CANCER AND METASTASIS REVIEWS
Volume -, Issue -, Pages -
Publisher
Springer Science and Business Media LLC
Online
2020-01-10
DOI
10.1007/s10555-019-09840-2
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Anti-tumor effect of sulfasalazine in neuroblastoma
- (2019) Marie R. Mooney et al. BIOCHEMICAL PHARMACOLOGY
- Cancer statistics, 2019
- (2019) Rebecca L. Siegel et al. CA-A CANCER JOURNAL FOR CLINICIANS
- Statins affect human glioblastoma and other cancers through TGF-β inhibition
- (2019) Aizhen Xiao et al. Oncotarget
- Challenges to curing primary brain tumours
- (2019) Kenneth Aldape et al. Nature Reviews Clinical Oncology
- Metformin Promotes Neuronal Differentiation via Crosstalk between Cdk5 and Sox6 in Neuroblastoma Cells
- (2019) Thunwa Binlateh et al. Evidence-based Complementary and Alternative Medicine
- Drug repurposing in oncology: Compounds, pathways, phenotypes and computational approaches for colorectal cancer
- (2019) Patrycja Nowak-Sliwinska et al. BIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON CANCER
- Cancer Stem Cells in Neuroblastoma: Expanding the Therapeutic Frontier
- (2019) Hisham F. Bahmad et al. Frontiers in Molecular Neuroscience
- Combination of clotam and vincristine enhances anti-proliferative effect in medulloblastoma cells
- (2019) Shruti Patil et al. GENE
- Down-regulation of TrkB expression and signalling by valproic acid and other histone deacetylase inhibitors
- (2019) Simona Dedoni et al. JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS
- Identification of GSK3β inhibitor kenpaullone as a temozolomide enhancer against glioblastoma
- (2019) Tomohiro Kitabayashi et al. Scientific Reports
- Simvastatin Induces Apoptosis in Medulloblastoma Brain Tumor Cells via Mevalonate Cascade Prenylation Substrates
- (2019) Kimia Sheikholeslami et al. Cancers
- Mebendazole as a Candidate for Drug Repurposing in Oncology: An Extensive Review of Current Literature
- (2019) Guerini et al. Cancers
- Autophagy inhibition improves the cytotoxic effects of receptor tyrosine kinase inhibitors
- (2018) Sanja Aveic et al. Cancer Cell International
- Establishing a Preclinical Multidisciplinary Board for Brain Tumors
- (2018) Birgit V. Nimmervoll et al. CLINICAL CANCER RESEARCH
- Repositioning of the antipsychotic trifluoperazine: Synthesis, biological evaluation and in silico study of trifluoperazine analogs as anti-glioblastoma agents
- (2018) Seokmin Kang et al. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
- The Histone Deacetylase Inhibitor Valproic Acid Exerts a Synergistic Cytotoxicity with the DNA-Damaging Drug Ellipticine in Neuroblastoma Cells
- (2018) Tereza Cerna et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Tumorigenic proteins upregulated in the MYCN-amplified IMR-32 human neuroblastoma cells promote proliferation and migration
- (2018) Hayat Zaatiti et al. INTERNATIONAL JOURNAL OF ONCOLOGY
- A High-Content Screening of Anticancer Compounds Suggests the Multiple Tyrosine Kinase Inhibitor Ponatinib for Repurposing in Neuroblastoma Therapy
- (2018) Viktoryia Sidarovich et al. MOLECULAR CANCER THERAPEUTICS
- Molecular and functional analysis of anchorage independent, treatment-evasive neuroblastoma tumorspheres with enhanced malignant properties: A possible explanation for radio-therapy resistance
- (2018) Tamara J. Abou-Antoun et al. PLoS One
- Metformin Treatment Inhibits Motility and Invasion of Glioblastoma Cancer Cells
- (2018) Marwa Al Hassan et al. Analytical Cellular Pathology
- HDL nanoparticles targeting sonic hedgehog subtype medulloblastoma
- (2018) Jonathan B. Bell et al. Scientific Reports
- Antagonistic role of GSK3 isoforms in glioma survival
- (2018) Vidhi Vashishtha et al. Journal of Cancer
- Drug Repositioning in Glioblastoma: A Pathway Perspective
- (2018) Sze Kiat Tan et al. Frontiers in Pharmacology
- Drug Repurposing of Metabolic Agents in Malignant Glioma
- (2018) Corinna Seliger et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Treatment of Alzheimer's Disease with the GSK-3 Inhibitor Tideglusib: A Pilot Study
- (2018) Teodoro del Ser et al. JOURNAL OF ALZHEIMERS DISEASE
- Phenformin and metformin inhibit growth and migration of LN229 glioma cells in vitro and in vivo
- (2018) Yanmin Wang et al. OncoTargets and Therapy
- The Akt/mTOR pathway in cancer stem/progenitor cells is a potential therapeutic target for glioblastoma and neuroblastoma
- (2018) Hisham F. Bahmad et al. Oncotarget
- Valproic acid suppresses Warburg effect and tumor progression in neuroblastoma
- (2018) Erhu Fang et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Thioridazine inhibits autophagy and sensitizes glioblastoma cells to temozolomide
- (2018) Tor‐Christian Johannessen et al. INTERNATIONAL JOURNAL OF CANCER
- Angiotensin II receptor blockers are safe in patients with prior angioedema related to angiotensin-converting enzyme inhibitors - a nationwide registry-based cohort study
- (2018) Eva Rye Rasmussen et al. JOURNAL OF INTERNAL MEDICINE
- Statins: a new approach to combat temozolomide chemoresistance in glioblastoma
- (2018) Shahla Shojaei et al. JOURNAL OF INVESTIGATIVE MEDICINE
- Systems biology–based drug repositioning identifies digoxin as a potential therapy for groups 3 and 4 medulloblastoma
- (2018) Lei Huang et al. Science Translational Medicine
- Temozolomide with or without Radiotherapy in Patients with Newly Diagnosed Glioblastoma Multiforme: A Meta-Analysis
- (2017) Enshan Feng et al. EUROPEAN NEUROLOGY
- Comparison of gefitinib, erlotinib and afatinib in non-small cell lung cancer: A meta-analysis
- (2017) Zuyao Yang et al. INTERNATIONAL JOURNAL OF CANCER
- P450 inhibitor ketoconazole increased the intratumor drug levels and antitumor activity of fenretinide in human neuroblastoma xenograft models
- (2017) Lluis Lopez-Barcons et al. INTERNATIONAL JOURNAL OF CANCER
- Pediatric Gliomas: Current Concepts on Diagnosis, Biology, and Clinical Management
- (2017) Dominik Sturm et al. JOURNAL OF CLINICAL ONCOLOGY
- Drug repurposing for the treatment of glioblastoma multiforme
- (2017) Claudia Abbruzzese et al. JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH
- The Drug Repurposing Hub: a next-generation drug library and information resource
- (2017) Steven M Corsello et al. NATURE MEDICINE
- Pediatric low-grade gliomas: next biologically driven steps
- (2017) David T W Jones et al. NEURO-ONCOLOGY
- Brain Cancer Stem Cells in Adults and Children: Cell Biology and Therapeutic Implications
- (2017) Tamara J. Abou-Antoun et al. Neurotherapeutics
- Targeting the renin-angiotensin system to improve cancer treatment: Implications for immunotherapy
- (2017) Matthias Pinter et al. Science Translational Medicine
- FTY-720 induces apoptosis in neuroblastoma via multiple signaling pathways
- (2017) Ingo Lange et al. Oncotarget
- High-grade glioma in very young children: a rare and particular patient population
- (2017) Moatasem El-Ayadi et al. Oncotarget
- Targeting of PHOX2B expression allows the identification of drugs effective in counteracting neuroblastoma cell growth
- (2017) Eleonora Di Zanni et al. Oncotarget
- Mevalonate Cascade Inhibition by Simvastatin Induces the Intrinsic Apoptosis Pathway via Depletion of Isoprenoids in Tumor Cells
- (2017) Javad Alizadeh et al. Scientific Reports
- Giving Drugs a Second Chance: Overcoming Regulatory and Financial Hurdles in Repurposing Approved Drugs As Cancer Therapeutics
- (2017) J. Javier Hernandez et al. Frontiers in Oncology
- Treatment of Glioblastoma
- (2017) Joo Yeon Nam et al. Journal of Oncology Practice
- Editorial: New Insights into a Classical Pathway: Key Roles of the Mevalonate Cascade in Different Diseases (Part II)
- (2017) Amir A. Zeki et al. Current Molecular Pharmacology
- Probenecid Sensitizes Neuroblastoma Cancer Stem Cells to Cisplatin
- (2016) Denise Campos-Arroyo et al. CANCER INVESTIGATION
- Tideglusib induces apoptosis in human neuroblastoma IMR32 cells, provoking sub-G 0 /G 1 accumulation and ROS generation
- (2016) Theodore Lemuel Mathuram et al. ENVIRONMENTAL TOXICOLOGY AND PHARMACOLOGY
- Targeting specificity protein 1 transcription factor and survivin using tolfenamic acid for inhibiting Ewing sarcoma cell growth
- (2016) Sagar Shelake et al. INVESTIGATIONAL NEW DRUGS
- In vitro models of medulloblastoma: Choosing the right tool for the job
- (2016) Delyan P. Ivanov et al. JOURNAL OF BIOTECHNOLOGY
- Nuclear GSK3β promotes tumorigenesis by phosphorylating KDM1A and inducing its deubiquitylation by USP22
- (2016) Aidong Zhou et al. NATURE CELL BIOLOGY
- PPAR Gamma in Neuroblastoma: The Translational Perspectives of Hypoglycemic Drugs
- (2016) Serena Vella et al. PPAR Research
- Cinacalcet inhibits neuroblastoma tumor growth and upregulates cancer-testis antigens
- (2016) Carlos J. Rodríguez-Hernández et al. Oncotarget
- Repurposing phenformin for the targeting of glioma stem cells and the treatment of glioblastoma
- (2016) Wei Jiang et al. Oncotarget
- Valproic Acid Increases CD133 Positive Cells that Show Low Sensitivity to Cytostatics in Neuroblastoma
- (2016) Mohamed Ashraf Khalil et al. PLoS One
- Fluvoxamine, an anti-depressant, inhibits human glioblastoma invasion by disrupting actin polymerization
- (2016) Keiichiro Hayashi et al. Scientific Reports
- Fenofibrate suppressed proliferation and migration of human neuroblastoma cells via oxidative stress dependent of TXNIP upregulation
- (2015) Cunjin Su et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Nifurtimox reduces N-Myc expression and aerobic glycolysis in neuroblastoma
- (2015) Karin Melanie Cabanillas Stanchi et al. CANCER BIOLOGY & THERAPY
- Global Transcriptional Changes Following Statin Treatment in Breast Cancer
- (2015) O. Bjarnadottir et al. CLINICAL CANCER RESEARCH
- Brain Penetration and Efficacy of Different Mebendazole Polymorphs in a Mouse Brain Tumor Model
- (2015) R.-Y. Bai et al. CLINICAL CANCER RESEARCH
- The synergistic effects of DNA-damaging drugs cisplatin and etoposide with a histone deacetylase inhibitor valproate in high-risk neuroblastoma cells
- (2015) TOMAS GROH et al. INTERNATIONAL JOURNAL OF ONCOLOGY
- An in vivo screen identifies ependymoma oncogenes and tumor-suppressor genes
- (2015) Kumarasamypet M Mohankumar et al. NATURE GENETICS
- Remaining Challenges in Childhood Cancer and Newer Targeted Therapeutics
- (2015) Malcolm A. Smith et al. PEDIATRIC CLINICS OF NORTH AMERICA
- Ibuprofen and Diclofenac Restrict Migration and Proliferation of Human Glioma Cells by Distinct Molecular Mechanisms
- (2015) Verena Leidgens et al. PLoS One
- COX/mPGES-1/PGE2pathway depicts an inflammatory-dependent high-risk neuroblastoma subset
- (2015) Karin Larsson et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Association between AT1 and AT2 angiotensin II receptor expression with cell proliferation and angiogenesis in operable breast cancer
- (2015) Oscar Arrieta et al. TUMOR BIOLOGY
- Antibiotic drug tigecycline reduces neuroblastoma cells proliferation by inhibiting Akt activation in vitro and in vivo
- (2015) Xiaoxia Zhong et al. TUMOR BIOLOGY
- The effect of statins on cancer cells—review
- (2015) Lucyna Matusewicz et al. TUMOR BIOLOGY
- HDAC inhibitors suppress c-Jun/Fra-1-mediated proliferation through transcriptionally downregulating MKK7 and Raf1 in neuroblastoma cells
- (2015) Weiwen He et al. Oncotarget
- Simvastatin-induced breast cancer cell death and deactivation of PI3K/Akt and MAPK/ERK signalling are reversed by metabolic products of the mevalonate pathway
- (2015) Tingting Wang et al. Oncotarget
- Identification of flubendazole as potential anti-neuroblastoma compound in a large cell line screen
- (2015) Martin Michaelis et al. Scientific Reports
- Perhexiline maleate enhances antitumor efficacy of cisplatin in neuroblastoma by inducing over-expression of NDM29 ncRNA
- (2015) Serena Vella et al. Scientific Reports
- Metformin and Ara-a Effectively Suppress Brain Cancer by Targeting Cancer Stem/Progenitor Cells
- (2015) Tarek H. Mouhieddine et al. Frontiers in Neuroscience
- Hedgehog Signaling in the Maintenance of Cancer Stem Cells
- (2015) Catherine Cochrane et al. Cancers
- Anti-tumor activity of the beta-adrenergic receptor antagonist propranolol in neuroblastoma
- (2015) Jennifer K Wolter et al. Oncotarget
- Metformin and trametinib have synergistic effects on cell viability and tumor growth in NRAS mutant cancer
- (2015) Igor Vujic et al. Oncotarget
- Targeting ornithine decarboxylase reverses the LIN28/Let-7 axis and inhibits glycolytic metabolism in neuroblastoma
- (2015) Ann M. Lozier et al. Oncotarget
- Metformin impairs Rho GTPase signaling to induce apoptosis in neuroblastoma cells and inhibits growth of tumors in the xenograft mouse model of neuroblastoma
- (2015) Ambrish Kumar et al. Oncotarget
- Metformin inhibition of neuroblastoma cell proliferation is differently modulated by cell differentiation induced by retinoic acid or overexpression of NDM29 non-coding RNA
- (2014) Delfina Costa et al. Cancer Cell International
- Rapamycin: One Drug, Many Effects
- (2014) Jing Li et al. Cell Metabolism
- Celecoxib Suppresses the Phosphorylation of STAT3 Protein and Can Enhance the Radiosensitivity of Medulloblastoma-Derived Cancer Stem-Like Cells
- (2014) Meng-Yin Yang et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Repurposing the Antihelmintic Mebendazole as a Hedgehog Inhibitor
- (2014) A. R. Larsen et al. MOLECULAR CANCER THERAPEUTICS
- A phase 2 trial of the GSK-3 inhibitor tideglusib in progressive supranuclear palsy
- (2014) Eduardo Tolosa et al. MOVEMENT DISORDERS
- Effective treatment of diverse medulloblastoma models with mebendazole and its impact on tumor angiogenesis
- (2014) Ren-Yuan Bai et al. NEURO-ONCOLOGY
- TL-118 and Gemcitabine Drug Combination Display Therapeutic Efficacy in a MYCN Amplified Orthotopic Neuroblastoma Murine Model – Evaluation by MRI
- (2014) Chani Komar-Stossel et al. PLoS One
- Inhibition of epidermal growth factor signaling by the cardiac glycoside ouabain in medulloblastoma
- (2014) Daniel Wolle et al. Cancer Medicine
- GSK-3β, a pivotal kinase in Alzheimer disease
- (2014) MarÃa Llorens-MarÃtin et al. Frontiers in Molecular Neuroscience
- Gliomas in Children
- (2013) Jane E. Minturn et al. Current Treatment Options in Neurology
- C-erbB2/HER2 in Human Gliomas, Medulloblastomas, and Meningiomas
- (2013) Ingunn Syversen Waage et al. INTERNATIONAL JOURNAL OF SURGICAL PATHOLOGY
- Anticancer activity of tolfenamic acid in medulloblastoma: a preclinical study
- (2013) Don Eslin et al. TUMOR BIOLOGY
- Differential effect of long-term drug selection with doxorubicin and vorinostat on neuroblastoma cells with cancer stem cell characteristics
- (2013) X Zheng et al. Cell Death & Disease
- Identification of FDA-approved Drugs Targeting Breast Cancer Stem Cells Along With Biomarkers of Sensitivity
- (2013) Poornima Bhat-Nakshatri et al. Scientific Reports
- Valproic acid shows a potent antitumor effect with alteration of DNA methylation in neuroblastoma
- (2012) Song Gu et al. ANTI-CANCER DRUGS
- A statin-regulated microRNA represses human c-Myc expression and function
- (2012) Apana A. L. Takwi et al. EMBO Molecular Medicine
- Molecular subgroups of medulloblastoma
- (2012) Paul A Northcott et al. Expert Review of Neurotherapeutics
- Diclofenac inhibits lactate formation and efficiently counteracts local immune suppression in a murine glioma model
- (2012) Sridhar R. Chirasani et al. INTERNATIONAL JOURNAL OF CANCER
- Sodium valproate potentiates staurosporine-induced apoptosis in neuroblastoma cells via Akt/survivin independently of HDAC inhibition
- (2012) Reecha D. Shah et al. JOURNAL OF CELLULAR BIOCHEMISTRY
- Zoledronate Sensitizes Neuroblastoma-derived Tumor-initiating Cells to Cytolysis Mediated by Human γδ T Cells
- (2012) Nobuhiro Nishio et al. JOURNAL OF IMMUNOTHERAPY
- Expression of O6-methylguanine DNA methyltransferase (MGMT) and immunohistochemical analysis of 12 pineal parenchymal tumors
- (2012) Hiromi Kanno et al. NEUROPATHOLOGY
- A feasibility and efficacy study of rapamycin and erlotinib for recurrent pediatric low-grade glioma (LGG)
- (2012) Michal Yalon et al. PEDIATRIC BLOOD & CANCER
- Molecular subgroups of medulloblastoma: the current consensus
- (2011) Michael D. Taylor et al. ACTA NEUROPATHOLOGICA
- Mapping Cancer Origins
- (2011) Richard J. Gilbertson CELL
- Challenging issues in pediatric oncology
- (2011) Ching-Hon Pui et al. Nature Reviews Clinical Oncology
- Childhood brain tumors: epidemiology, current management and future directions
- (2011) Ian F. Pollack et al. Nature Reviews Neurology
- The Physiological Significance of the Cardiotonic Steroid/Ouabain-Binding Site of the Na,K-ATPase
- (2010) Jerry B Lingrel Annual Review of Physiology
- Celecoxib enhances radiosensitivity in medulloblastoma-derived CD133-positive cells
- (2010) Kuan-Hsuan Chen et al. CHILDS NERVOUS SYSTEM
- Integrative Genomic Analysis of Medulloblastoma Identifies a Molecular Subgroup That Drives Poor Clinical Outcome
- (2010) Yoon-Jae Cho et al. JOURNAL OF CLINICAL ONCOLOGY
- Enhancement of vinorelbine-induced cytotoxicity and apoptosis by clomipramine and lithium chloride in human neuroblastoma cancer cell line SH-SY5Y
- (2010) Ayhan Bilir et al. JOURNAL OF NEURO-ONCOLOGY
- Sunitinib induces PTEN expression and inhibits PDGFR signaling and migration of medulloblastoma cells
- (2010) Thamara J. Abouantoun et al. JOURNAL OF NEURO-ONCOLOGY
- Potential Therapeutic Effect of Glycogen Synthase Kinase 3 Inhibition against Human Glioblastoma
- (2009) K. Miyashita et al. CLINICAL CANCER RESEARCH
- The antiretroviral nucleoside analogue Abacavir reduces cell growth and promotes differentiation of human medulloblastoma cells
- (2009) Alessandra Rossi et al. INTERNATIONAL JOURNAL OF CANCER
- Pediatric Low-Grade Gliomas
- (2009) Angela J. Sievert et al. JOURNAL OF CHILD NEUROLOGY
- Response of an adult patient with pineoblastoma to vorinostat and retinoic acid
- (2009) Rebecca DeBoer et al. JOURNAL OF NEURO-ONCOLOGY
- Nifurtimox Induces Apoptosis of Neuroblastoma Cells In Vitro and In Vivo
- (2009) Giselle L. Saulnier Sholler et al. JOURNAL OF PEDIATRIC HEMATOLOGY ONCOLOGY
- Imatinib blocks migration and invasion of medulloblastoma cells by concurrently inhibiting activation of platelet-derived growth factor receptor and transactivation of epidermal growth factor receptor
- (2009) T. J. Abouantoun et al. MOLECULAR CANCER THERAPEUTICS
- Targeting telomerase for cancer therapeutics
- (2008) J W Shay et al. BRITISH JOURNAL OF CANCER
- A Review of the Pharmacokinetics of Abacavir
- (2008) Geoffrey J Yuen et al. CLINICAL PHARMACOKINETICS
- New developments in medulloblastoma treatment: the potential of a cyclopamine–lovastatin combination
- (2008) Eli E Bar et al. EXPERT OPINION ON INVESTIGATIONAL DRUGS
- Lithium inhibits invasion of glioma cells; possible involvement of glycogen synthase kinase-3
- (2008) Michal O. Nowicki et al. NEURO-ONCOLOGY
- Biological background of pediatric medulloblastoma and ependymoma: A review from a translational research perspective
- (2008) Judith M. de Bont et al. NEURO-ONCOLOGY
- Tumor-growth–promoting cyclooxygenase-2 prostaglandin E2 pathway provides medulloblastoma therapeutic targets
- (2008) Ninib Baryawno et al. NEURO-ONCOLOGY
- Integrated Genomics Identifies Five Medulloblastoma Subtypes with Distinct Genetic Profiles, Pathway Signatures and Clinicopathological Features
- (2008) Marcel Kool et al. PLoS One
- Telomerase and its potential for therapeutic intervention
- (2007) P Phatak et al. BRITISH JOURNAL OF PHARMACOLOGY
Find the ideal target journal for your manuscript
Explore over 38,000 international journals covering a vast array of academic fields.
SearchBecome a Peeref-certified reviewer
The Peeref Institute provides free reviewer training that teaches the core competencies of the academic peer review process.
Get Started