Brain Cancer Stem Cells in Adults and Children: Cell Biology and Therapeutic Implications
Published 2017 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Brain Cancer Stem Cells in Adults and Children: Cell Biology and Therapeutic Implications
Authors
Keywords
Cancer stem cells, Childhood brain tumors, Glioblastoma, Epigenetics, Microenvironment, Therapeutic implications
Journal
Neurotherapeutics
Volume 14, Issue 2, Pages 372-384
Publisher
Springer Nature
Online
2017-04-04
DOI
10.1007/s13311-017-0524-0
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Pharmacological Targeting of the Histone Chaperone Complex FACT Preferentially Eliminates Glioblastoma Stem Cells and Prolongs Survival in Preclinical Models
- (2016) Josephine Kam Tai Dermawan et al. CANCER RESEARCH
- Deubiquitinase USP13 maintains glioblastoma stem cells by antagonizing FBXL14-mediated Myc ubiquitination
- (2016) Xiaoguang Fang et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Transforming growth factor-β and stem cell markers are highly expressed around necrotic areas in glioblastoma
- (2016) Yasuo Iwadate et al. JOURNAL OF NEURO-ONCOLOGY
- Astrocyte Elevated Gene-1 Regulates β-Catenin Signaling to Maintain Glioma Stem-like Stemness and Self-Renewal
- (2016) Bin Hu et al. MOLECULAR CANCER RESEARCH
- An ID2-dependent mechanism for VHL inactivation in cancer
- (2016) Sang Bae Lee et al. NATURE
- Pediatric Primitive Neuroectodermal Tumors of the Central Nervous System Differentially Express Granzyme Inhibitors
- (2016) Jeroen F. Vermeulen et al. PLoS One
- TGFβ-Responsive HMOX1 Expression Is Associated with Stemness and Invasion in Glioblastoma Multiforme
- (2016) Dhiman Ghosh et al. STEM CELLS
- Cancer Stem Cell-Secreted Macrophage Migration Inhibitory Factor Stimulates Myeloid Derived Suppressor Cell Function and Facilitates Glioblastoma Immune Evasion
- (2016) Balint Otvos et al. STEM CELLS
- Neural Stem Cells and Nutrients: Poised Between Quiescence and Exhaustion
- (2016) Virve Cavallucci et al. TRENDS IN ENDOCRINOLOGY AND METABOLISM
- The ID1-CULLIN3 Axis Regulates Intracellular SHH and WNT Signaling in Glioblastoma Stem Cells
- (2016) Xun Jin et al. Cell Reports
- The Long Non-coding RNA HIF1A-AS2 Facilitates the Maintenance of Mesenchymal Glioblastoma Stem-like Cells in Hypoxic Niches
- (2016) Marco Mineo et al. Cell Reports
- Glioma Stem Cells and Their Microenvironments: Providers of Challenging Therapeutic Targets
- (2016) Elena Codrici et al. Stem Cells International
- A Novel Mouse Model of Diffuse Intrinsic Pontine Glioma Initiated in Pax3-Expressing Cells
- (2016) Katherine L. Misuraca et al. NEOPLASIA
- Adult Neurogenesis and Gliogenesis: Possible Mechanisms for Neurorestoration
- (2016) Zoltán Rusznák et al. Experimental Neurobiology
- Pyrvinium Targets CD133 in Human Glioblastoma Brain Tumor-Initiating Cells
- (2015) C. Venugopal et al. CLINICAL CANCER RESEARCH
- Cancer stem cells in glioblastoma
- (2015) Justin D. Lathia et al. GENES & DEVELOPMENT
- Vismodegib Exerts Targeted Efficacy Against Recurrent Sonic Hedgehog–Subgroup Medulloblastoma: Results From Phase II Pediatric Brain Tumor Consortium Studies PBTC-025B and PBTC-032
- (2015) Giles W. Robinson et al. JOURNAL OF CLINICAL ONCOLOGY
- MiRNA-21 silencing mediated by tumor-targeted nanoparticles combined with sunitinib: A new multimodal gene therapy approach for glioblastoma
- (2015) Pedro M. Costa et al. JOURNAL OF CONTROLLED RELEASE
- Targeting Hypoxia-Inducible Factor 1α in a New Orthotopic Model of Glioblastoma Recapitulating the Hypoxic Tumor Microenvironment
- (2015) Fares Nigim et al. JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY
- Endothelial cells induce cancer stem cell features in differentiated glioblastoma cells via bFGF
- (2015) Evelyn Fessler et al. Molecular Cancer
- Periostin secreted by glioblastoma stem cells recruits M2 tumour-associated macrophages and promotes malignant growth
- (2015) Wenchao Zhou et al. NATURE CELL BIOLOGY
- Pediatric medulloblastoma xenografts including molecular subgroup 3 and CD133+ and CD15+ cells are sensitive to killing by oncolytic herpes simplex viruses
- (2015) Gregory K. Friedman et al. NEURO-ONCOLOGY
- American Brain Tumor Association Adolescent and Young Adult Primary Brain and Central Nervous System Tumors Diagnosed in the United States in 2008-2012
- (2015) Quinn T. Ostrom et al. NEURO-ONCOLOGY
- The intersection of cancer, cancer stem cells, and the immune system: therapeutic opportunities
- (2015) Daniel J. Silver et al. NEURO-ONCOLOGY
- CD133 and DNA-PK regulate MDR1 via the PI3K- or Akt-NF-κB pathway in multidrug-resistant glioblastoma cells in vitro
- (2015) G Xi et al. ONCOGENE
- Single cell-derived clonal analysis of human glioblastoma links functional and genomic heterogeneity
- (2015) Mona Meyer et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- HOXA13 is a potential GBM diagnostic marker and promotes glioma invasion by activating the Wnt and TGF-β pathways
- (2015) Ran Duan et al. Oncotarget
- Molecular and In Vivo Characterization of Cancer-Propagating Cells Derived from MYCN-Dependent Medulloblastoma
- (2015) Zai Ahmad et al. PLoS One
- Quiescent Sox2+ Cells Drive Hierarchical Growth and Relapse in Sonic Hedgehog Subgroup Medulloblastoma
- (2014) Robert J. Vanner et al. CANCER CELL
- Molecular Genetics of Gliomas
- (2014) Christina L. Appin et al. CANCER JOURNAL
- Reconstructing and Reprogramming the Tumor-Propagating Potential of Glioblastoma Stem-like Cells
- (2014) Mario L. Suvà et al. CELL
- TRPM7 channels regulate glioma stem cell through STAT3 and Notch signaling pathways
- (2014) Mingli Liu et al. CELLULAR SIGNALLING
- Abrogation of radioresistance in glioblastoma stem-like cells by inhibition of ATM kinase
- (2014) Ross Carruthers et al. Molecular Oncology
- Profilin-1 phosphorylation directs angiocrine expression and glioblastoma progression through HIF-1α accumulation
- (2014) Yi Fan et al. NATURE CELL BIOLOGY
- The genomic landscape of diffuse intrinsic pontine glioma and pediatric non-brainstem high-grade glioma
- (2014) Gang Wu et al. NATURE GENETICS
- T-cell TGF- signaling abrogation restricts medulloblastoma progression
- (2014) D. Gate et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Use of human embryonic stem cells to model pediatric gliomas with H3.3K27M histone mutation
- (2014) Kosuke Funato et al. SCIENCE
- The Zinc Finger Transcription Factor ZFX Is Required for Maintaining the Tumorigenic Potential of Glioblastoma Stem Cells
- (2014) Xiaoguang Fang et al. STEM CELLS
- Cancer Stem Cell-Specific Scavenger Receptor CD36 Drives Glioblastoma Progression
- (2014) James S. Hale et al. STEM CELLS
- ZFHX4 Interacts with the NuRD Core Member CHD4 and Regulates the Glioblastoma Tumor-Initiating Cell State
- (2014) Yakov Chudnovsky et al. Cell Reports
- Sox2 Promotes Malignancy in Glioblastoma by Regulating Plasticity and Astrocytic Differentiation
- (2014) Artem D. Berezovsky et al. NEOPLASIA
- Immunovirotherapy for the treatment of glioblastoma
- (2014) Tooba A Cheema et al. OncoImmunology
- Evaluation of Histone 3 Lysine 27 Trimethylation (H3K27me3) and Enhancer of Zest 2 (EZH2) in Pediatric Glial and Glioneuronal Tumors Shows Decreased H3K27me3 inH3F3AK27M Mutant Glioblastomas
- (2013) Sriram Venneti et al. BRAIN PATHOLOGY
- Therapeutic vaccination against autologous cancer stem cells with mRNA-transfected dendritic cells in patients with glioblastoma
- (2013) Einar Osland Vik-Mo et al. CANCER IMMUNOLOGY IMMUNOTHERAPY
- Interleukin-6 is overexpressed and augments invasiveness of human glioma stem cells in vitro
- (2013) Bo Qiu et al. CLINICAL & EXPERIMENTAL METASTASIS
- Medulloblastoma molecular dissection
- (2013) Marc Remke et al. CURRENT OPINION IN ONCOLOGY
- Molecular neuro-oncology in clinical practice: a new horizon
- (2013) Michael Weller et al. LANCET ONCOLOGY
- DNA methylation: roles in mammalian development
- (2013) Zachary D. Smith et al. NATURE REVIEWS GENETICS
- TERT promoter mutations occur frequently in gliomas and a subset of tumors derived from cells with low rates of self-renewal
- (2013) P. J. Killela et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- MELK-Dependent FOXM1 Phosphorylation is Essential for Proliferation of Glioma Stem Cells
- (2013) Kaushal Joshi et al. STEM CELLS
- FoxG1 Interacts with Bmi1 to Regulate Self-Renewal and Tumorigenicity of Medulloblastoma Stem Cells
- (2013) Branavan Manoranjan et al. STEM CELLS
- Transcription factors FOXG1 and Groucho/TLE promote glioblastoma growth
- (2013) Federica Verginelli et al. Nature Communications
- An Aberrant Transcription Factor Network Essential for Wnt Signaling and Stem Cell Maintenance in Glioblastoma
- (2013) Esther Rheinbay et al. Cell Reports
- An Animal Model of MYC-Driven Medulloblastoma
- (2012) Yanxin Pei et al. CANCER CELL
- A Tumorigenic MLL-Homeobox Network in Human Glioblastoma Stem Cells
- (2012) M. Gallo et al. CANCER RESEARCH
- Hypoxia and hypoxia-inducible factors in glioblastoma multiforme progression and therapeutic implications
- (2012) Liuqi Yang et al. EXPERIMENTAL CELL RESEARCH
- Tumor-Associated Microglia/Macrophages Enhance the Invasion of Glioma Stem-like Cells via TGF- 1 Signaling Pathway
- (2012) X.-z. Ye et al. JOURNAL OF IMMUNOLOGY
- The good, the bad and the ugly: Epigenetic mechanisms in glioblastoma
- (2012) Helena Carén et al. MOLECULAR ASPECTS OF MEDICINE
- A restricted cell population propagates glioblastoma growth after chemotherapy
- (2012) Jian Chen et al. NATURE
- Somatic histone H3 alterations in pediatric diffuse intrinsic pontine gliomas and non-brainstem glioblastomas
- (2012) Gang Wu et al. NATURE GENETICS
- Standards of care for treatment of recurrent glioblastoma—are we there yet?
- (2012) Michael Weller et al. NEURO-ONCOLOGY
- Discovering gene–environment interactions in Glioblastoma through a comprehensive data integration bioinformatics method
- (2012) Brian Kunkle et al. NEUROTOXICOLOGY
- Elevated invasive potential of glioblastoma stem cells
- (2011) Lin Cheng et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Receptor Tyrosine Kinases and Targeted Cancer Therapeutics
- (2011) Kenji Takeuchi et al. BIOLOGICAL & PHARMACEUTICAL BULLETIN
- Endothelial Cells Create a Stem Cell Niche in Glioblastoma by Providing NOTCH Ligands That Nurture Self-Renewal of Cancer Stem-Like Cells
- (2011) T. S. Zhu et al. CANCER RESEARCH
- Hypoxia-induced mixed-lineage leukemia 1 regulates glioma stem cell tumorigenic potential
- (2011) J M Heddleston et al. CELL DEATH AND DIFFERENTIATION
- Challenges in Immunotherapy Presented by the Glioblastoma Multiforme Microenvironment
- (2011) Christopher Jackson et al. Clinical & Developmental Immunology
- Glioma Stem Cell Maintenance: The Role of the Microenvironment
- (2011) John M. Heddleston et al. CURRENT PHARMACEUTICAL DESIGN
- Phase I Trial of MK-0752 in Children With Refractory CNS Malignancies: A Pediatric Brain Tumor Consortium Study
- (2011) Maryam Fouladi et al. JOURNAL OF CLINICAL ONCOLOGY
- Microglial stress inducible protein 1 promotes proliferation and migration in human glioblastoma cells
- (2011) A.C.C. da Fonseca et al. NEUROSCIENCE
- Sonic hedgehog regulates Bmi1 in human medulloblastoma brain tumor-initiating cells
- (2011) X Wang et al. ONCOGENE
- Epidermal Growth Factor Receptor Expression Identifies Functionally and Molecularly Distinct Tumor-Initiating Cells in Human Glioblastoma Multiforme and Is Required for Gliomagenesis
- (2010) S. Mazzoleni et al. CANCER RESEARCH
- Integrin Alpha 6 Regulates Glioblastoma Stem Cells
- (2010) Justin D. Lathia et al. Cell Stem Cell
- TRRAP and the Maintenance of Stemness in Gliomas
- (2010) Nikki A. Charles et al. Cell Stem Cell
- NANOG regulates glioma stem cells and is essential in vivo acting in a cross-functional network with GLI1 and p53
- (2010) Marie Zbinden et al. EMBO JOURNAL
- Hypoxia-Inducible Factors Regulate Tumorigenic Capacity of Glioma Stem Cells
- (2009) Zhizhong Li et al. CANCER CELL
- Identification of CD15 as a Marker for Tumor-Propagating Cells in a Mouse Model of Medulloblastoma
- (2009) Tracy-Ann Read et al. CANCER CELL
- Gliomas induce and exploit microglial MT1-MMP expression for tumor expansion
- (2009) D. S. Markovic et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- STAT3 Is Required for Proliferation and Maintenance of Multipotency in Glioblastoma Stem Cells
- (2009) Maureen M. Sherry et al. STEM CELLS
- Epigenetic-Mediated Dysfunction of the Bone Morphogenetic Protein Pathway Inhibits Differentiation of Glioblastoma-Initiating Cells
- (2008) Jeongwu Lee et al. CANCER CELL
- Temozolomide Preferentially Depletes Cancer Stem Cells in Glioblastoma
- (2008) D. Beier et al. CANCER RESEARCH
- Targeting Cancer Stem Cells through L1CAM Suppresses Glioma Growth
- (2008) S. Bao et al. CANCER RESEARCH
- PI3K pathway regulates survival of cancer stem cells residing in the perivascular niche following radiation in medulloblastoma in vivo
- (2008) D. Hambardzumyan et al. GENES & DEVELOPMENT
- Comprehensive genomic characterization defines human glioblastoma genes and core pathways
- (2008) Roger McLendon et al. NATURE
- IDENTIFICATION OF A2B5+CD133− TUMOR-INITIATING CELLS IN ADULT HUMAN GLIOMAS
- (2008) Alfred T. Ogden et al. NEUROSURGERY
- An Integrated Genomic Analysis of Human Glioblastoma Multiforme
- (2008) D. W. Parsons et al. SCIENCE
- Hypoxia and HIF1α Repress the Differentiative Effects of BMPs in High-Grade Glioma
- (2008) Francesca Pistollato et al. STEM CELLS
- SOX2Silencing in Glioblastoma Tumor-Initiating Cells Causes Stop of Proliferation and Loss of Tumorigenicity
- (2008) Rosaria Maria Rita Gangemi et al. STEM CELLS
Create your own webinar
Interested in hosting your own webinar? Check the schedule and propose your idea to the Peeref Content Team.
Create NowBecome a Peeref-certified reviewer
The Peeref Institute provides free reviewer training that teaches the core competencies of the academic peer review process.
Get Started