Molecular subgroups of medulloblastoma: the current consensus

Pediatric and adult sonic hedgehog medulloblastomas are clinically and molecularly distinct

(2011) Paul A. Northcott et al.   ACTA NEUROPATHOLOGICA

Medulloblastoma: clinicopathological correlates of SHH, WNT, and non-SHH/WNT molecular subgroups

(2011) David W. Ellison et al.   ACTA NEUROPATHOLOGICA

Rapid Diagnosis of Medulloblastoma Molecular Subgroups

(2011) E. C. Schwalbe et al.   CLINICAL CANCER RESEARCH

Adult Medulloblastoma Comprises Three Major Molecular Variants

(2011) Marc Remke et al.   JOURNAL OF CLINICAL ONCOLOGY

FSTL5Is a Marker of Poor Prognosis in Non-WNT/Non-SHH Medulloblastoma

(2011) Marc Remke et al.   JOURNAL OF CLINICAL ONCOLOGY

Development and cancer of the cerebellum

(2011) Mary E. Hatten et al.   TRENDS IN NEUROSCIENCES

Preponderance of sonic hedgehog pathway activation characterizes adult medulloblastoma

(2010) Hani Al-Halabi et al.   ACTA NEUROPATHOLOGICA

Identification of a CpG Island Methylator Phenotype that Defines a Distinct Subgroup of Glioma

(2010) Houtan Noushmehr et al.   CANCER CELL

Heterogeneity of familial medulloblastoma and contribution of germline PTCH1 and SUFU mutations to sporadic medulloblastoma

(2010) Ingrid Slade et al.   Familial Cancer

Adult and Pediatric Medulloblastomas Are Genetically Distinct and Require Different Algorithms for Molecular Risk Stratification

(2010) Andrey Korshunov et al.   JOURNAL OF CLINICAL ONCOLOGY

TP53 Mutation Is Frequently Associated With CTNNB1 Mutation or MYCN Amplification and Is Compatible With Long-Term Survival in Medulloblastoma

(2010) Elke Pfaff et al.   JOURNAL OF CLINICAL ONCOLOGY

Integrative Genomic Analysis of Medulloblastoma Identifies a Molecular Subgroup That Drives Poor Clinical Outcome

(2010) Yoon-Jae Cho et al.   JOURNAL OF CLINICAL ONCOLOGY

Definition of Disease-Risk Stratification Groups in Childhood Medulloblastoma Using Combined Clinical, Pathologic, and Molecular Variables

(2010) David W. Ellison et al.   JOURNAL OF CLINICAL ONCOLOGY

Medulloblastoma Comprises Four Distinct Molecular Variants

(2010) Paul A. Northcott et al.   JOURNAL OF CLINICAL ONCOLOGY

Subtypes of medulloblastoma have distinct developmental origins

(2010) Paul Gibson et al.   NATURE

A pathway-based classification of human breast cancer

(2010) M. L. Gatza et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Genetic Landscape of the Childhood Cancer Medulloblastoma

(2010) D. W. Parsons et al.   SCIENCE

Identification of aSUFUgermline mutation in a family with Gorlin syndrome

(2009) L. Pastorino et al.   AMERICAN JOURNAL OF MEDICAL GENETICS PART A

An investigation of WNT pathway activation and association with survival in central nervous system primitive neuroectodermal tumours (CNS PNET)

(2009) H A Rogers et al.   BRITISH JOURNAL OF CANCER

OTX2 Is Critical for the Maintenance and Progression of Shh-Independent Medulloblastomas

(2009) D. C. Adamson et al.   CANCER RESEARCH

The miR-17/92 Polycistron Is Up-regulated in Sonic Hedgehog-Driven Medulloblastomas and Induced by N-myc in Sonic Hedgehog-Treated Cerebellar Neural Precursors

(2009) P. A. Northcott et al.   CANCER RESEARCH

Incomplete penetrance of the predisposition to medulloblastoma associated with germ-line SUFU mutations

(2009) L. Brugieres et al.   JOURNAL OF MEDICAL GENETICS

Beta-catenin status in paediatric medulloblastomas: correlation of immunohistochemical expression with mutational status, genetic profiles, and clinical characteristics

(2009) Sarah Fattet et al.   JOURNAL OF PATHOLOGY

Multiple recurrent genetic events converge on control of histone lysine methylation in medulloblastoma

(2009) Paul A Northcott et al.   NATURE GENETICS

Treatment of Medulloblastoma with Hedgehog Pathway Inhibitor GDC-0449

(2009) Charles M. Rudin et al.   NEW ENGLAND JOURNAL OF MEDICINE

Smoothened Mutation Confers Resistance to a Hedgehog Pathway Inhibitor in Medulloblastoma

(2009) R. L. Yauch et al.   SCIENCE

Integrated Genomics Identifies Five Medulloblastoma Subtypes with Distinct Genetic Profiles, Pathway Signatures and Clinicopathological Features

(2008) Marcel Kool et al.   PLoS One