Flow-enhanced priming of hESCs through H2B acetylation and chromatin decondensation

A LINE1-Nucleolin Partnership Regulates Early Development and ESC Identity

(2018) Michelle Percharde et al.   CELL

Mechanical remodeling of normally sized mammalian cells under a gravity vector

(2017) Chen Zhang et al.   FASEB JOURNAL

Dissecting the variation in transcriptional circuits between naive and primed pluripotent states

(2017) Aritra Deb et al.   FEBS LETTERS

Emerging roles of mechanical forces in chromatin regulation

(2017) Yekaterina A. Miroshnikova et al.   JOURNAL OF CELL SCIENCE

Chromatin and lamin A determine two different mechanical response regimes of the cell nucleus

(2017) Andrew D. Stephens et al.   MOLECULAR BIOLOGY OF THE CELL

Direct comparison of distinct naive pluripotent states in human embryonic stem cells

(2017) S. Warrier et al.   Nature Communications

Mechanical regulation of transcription controls Polycomb-mediated gene silencing during lineage commitment

(2016) Huy Quang Le et al.   NATURE CELL BIOLOGY

Transcription upregulation via force-induced direct stretching of chromatin

(2016) Arash Tajik et al.   NATURE MATERIALS

Dynamic stem cell states: naive to primed pluripotency in rodents and humans

(2016) Leehee Weinberger et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Histone modification profiling reveals differential signatures associated with human embryonic stem cell self-renewal and differentiation

(2016) Natarajan V. Bhanu et al.   PROTEOMICS

Differentiation alters stem cell nuclear architecture, mechanics, and mechano-sensitivity

(2016) Su-Jin Heo et al.   eLife

The Regulation of rRNA Gene Transcription during Directed Differentiation of Human Embryonic Stem Cells

(2016) Jessica L. Woolnough et al.   PLoS One

Pluripotent States of Human Embryonic Stem Cells

(2015) Yifei Chen et al.   Cellular Reprogramming

Stiffness of Hydrogels Regulates Cellular Reprogramming Efficiency Through Mesenchymal-to-Epithelial Transition and Stemness Markers 

(2015) Bogyu Choi et al.   MACROMOLECULAR BIOSCIENCE

Nuclear deformability and telomere dynamics are regulated by cell geometric constraints

(2015) Ekta Makhija et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

ADF and Cofilin1 Control Actin Stress Fibers, Nuclear Integrity, and Cell Survival

(2015) Georgios Kanellos et al.   Cell Reports

Biophysical Regulation of Chromatin Architecture Instills a Mechanical Memory in Mesenchymal Stem Cells

(2015) Su-Jin Heo et al.   Scientific Reports

Systematic Identification of Culture Conditions for Induction and Maintenance of Naive Human Pluripotency

(2014) Thorold W. Theunissen et al.   Cell Stem Cell

Sizing and shaping the nucleus: mechanisms and significance

(2014) Predrag Jevtić et al.   CURRENT OPINION IN CELL BIOLOGY

Auxetic nuclei in embryonic stem cells exiting pluripotency

(2014) Stefano Pagliara et al.   NATURE MATERIALS

The Adaptive Remodeling of Endothelial Glycocalyx in Response to Fluid Shear Stress

(2014) Ye Zeng et al.   PLoS One

Erasers of Histone Acetylation: The Histone Deacetylase Enzymes

(2014) E. Seto et al.   Cold Spring Harbor Perspectives in Biology

Mechanomics: an emerging field between biology and biomechanics

(2014) Jiawen Wang et al.   Protein & Cell

Embryonic and Induced Pluripotent Stem Cells: Understanding, Creating, and Exploiting the Nano-Niche for Regenerative Medicine

(2013) Emmajayne Kingham et al.   ACS Nano

Fluid Shear Stress on Endothelial Cells Modulates Mechanical Tension across VE-Cadherin and PECAM-1

(2013) Daniel E. Conway et al.   CURRENT BIOLOGY

Biophysical regulation of epigenetic state and cell reprogramming

(2013) Timothy L. Downing et al.   NATURE MATERIALS

Nuclear Lamin-A Scales with Tissue Stiffness and Enhances Matrix-Directed Differentiation

(2013) J. Swift et al.   SCIENCE

Mechanisms of nuclear actin in chromatin-remodeling complexes

(2013) Prabodh Kapoor et al.   TRENDS IN CELL BIOLOGY

Excitable Actin Dynamics in Lamellipodial Protrusion and Retraction

(2012) Gillian L. Ryan et al.   BIOPHYSICAL JOURNAL

Chromatin Decondensation and Nuclear Softening Accompany Nanog Downregulation in Embryonic Stem Cells

(2012) Kevin J. Chalut et al.   BIOPHYSICAL JOURNAL

Fluid flows and forces in development: functions, features and biophysical principles

(2012) J. B. Freund et al.   DEVELOPMENT

Physical tethering and volume exclusion determine higher-order genome organization in budding yeast

(2012) H. Tjong et al.   GENOME RESEARCH

Mapping the Mechanome of Live Stem Cells Using a Novel Method to Measure Local Strain Fields In Situ at the Fluid-Cell Interface

(2012) Min Jae Song et al.   PLoS One

Biophysical Regulation of Histone Acetylation in Mesenchymal Stem Cells

(2011) Yuan Li et al.   BIOPHYSICAL JOURNAL

Shear stress magnitude is critical in regulating the differentiation of mesenchymal stem cells even with endothelial growth medium

(2011) Dong Hwa Kim et al.   BIOTECHNOLOGY LETTERS

MAP3K4/CBP-Regulated H2B Acetylation Controls Epithelial-Mesenchymal Transition in Trophoblast Stem Cells

(2011) Amy N. Abell et al.   Cell Stem Cell

Mechanical control of stem cell differentiation

(2011) Dekel Dado et al.   Regenerative Medicine

Physical and Functional HAT/HDAC Interplay Regulates Protein Acetylation Balance

(2010) Alessia Peserico et al.   JOURNAL OF BIOMEDICINE AND BIOTECHNOLOGY

Manipulating Actin Dynamics Affects Human In Vitro Decidualization1

(2009) Ivanna Ihnatovych et al.   BIOLOGY OF REPRODUCTION

Can shear stress direct stem cell fate?

(2009) Sarah Stolberg et al.   BIOTECHNOLOGY PROGRESS

Naive and Primed Pluripotent States

(2009) Jennifer Nichols et al.   Cell Stem Cell

Structure and Epigenetics of Nucleoli in Comparison With Non-nucleolar Compartments

(2009) Eva Bártová et al.   JOURNAL OF HISTOCHEMISTRY & CYTOCHEMISTRY

Biomechanical forces promote embryonic haematopoiesis

(2009) Luigi Adamo et al.   NATURE

Mechanical Control of Tissue Morphogenesis

(2008) Parth Patwari et al.   CIRCULATION RESEARCH

The Histone Acetyltransferase PCAF Associates with Actin and hnRNP U for RNA Polymerase II Transcription

(2008) A. Obrdlik et al.   MOLECULAR AND CELLULAR BIOLOGY

Human embryonic stem cells: lessons from stem cell niches in vivo

(2008) Sean C Bendall et al.   Regenerative Medicine

Reversal of Cell Polarity and Actin-Myosin Cytoskeleton Reorganization under Mechanical and Chemical Stimulation

(2007) Jérémie Dalous et al.   BIOPHYSICAL JOURNAL