Direct comparison of distinct naive pluripotent states in human embryonic stem cells

CDK1-PDK1-PI3K/Akt signaling pathway regulates embryonic and induced pluripotency

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Naive Human Pluripotent Cells Feature a Methylation Landscape Devoid of Blastocyst or Germline Memory

(2016) William A. Pastor et al.   Cell Stem Cell

SOX17 Is a Critical Specifier of Human Primordial Germ Cell Fate

(2015) Naoko Irie et al.   CELL

Metabolic exit from naive pluripotency

(2015) Jun Wu et al.   NATURE CELL BIOLOGY

The metabolome regulates the epigenetic landscape during naive-to-primed human embryonic stem cell transition

(2015) Henrik Sperber et al.   NATURE CELL BIOLOGY

Metabolic determinants of embryonic development and stem cell fate

(2015) Clifford D. L. Folmes et al.   REPRODUCTION FERTILITY AND DEVELOPMENT

Alternative Routes to Induce Naïve Pluripotency in Human Embryonic Stem Cells

(2015) Galbha Duggal et al.   STEM CELLS

Reinforcement of STAT3 activity reprogrammes human embryonic stem cells to naive-like pluripotency

(2015) Hongwei Chen et al.   Nature Communications

Comparative computational analysis of pluripotency in human and mouse stem cells

(2015) Mathias Ernst et al.   Scientific Reports

Resetting Transcription Factor Control Circuitry toward Ground-State Pluripotency in Human

(2014) Yasuhiro Takashima et al.   CELL

The Naive State of Human Pluripotent Stem Cells: A Synthesis of Stem Cell and Preimplantation Embryo Transcriptome Analyses

(2014) Kevin Huang et al.   Cell Stem Cell

Systematic Identification of Culture Conditions for Induction and Maintenance of Naive Human Pluripotency

(2014) Thorold W. Theunissen et al.   Cell Stem Cell

Differential effects of Akt isoforms on somatic cell reprogramming

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Derivation of naive human embryonic stem cells

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PRDM14: a unique regulator for pluripotency and epigenetic reprogramming

(2014) Fumio Nakaki et al.   TRENDS IN BIOCHEMICAL SCIENCES

The Epithelial-Mesenchymal Transition Factor SNAIL Paradoxically Enhances Reprogramming

(2014) Juli J. Unternaehrer et al.   Stem Cell Reports

Pathview: an R/Bioconductor package for pathway-based data integration and visualization

(2013) Weijun Luo et al.   BIOINFORMATICS

PRDM14 Ensures Naive Pluripotency through Dual Regulation of Signaling and Epigenetic Pathways in Mouse Embryonic Stem Cells

(2013) Masashi Yamaji et al.   Cell Stem Cell

Prdm14 promotes germline fate and naive pluripotency by repressing FGF signalling and DNA methylation

(2013) Nils Grabole et al.   EMBO REPORTS

Naive-like Conversion Overcomes the Limited Differentiation Capacity of Induced Pluripotent Stem Cells

(2013) Arata Honda et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Derivation of novel human ground state naive pluripotent stem cells

(2013) Ohad Gafni et al.   NATURE

Directed differentiation of forebrain GABA interneurons from human pluripotent stem cells

(2013) Yan Liu et al.   Nature Protocols

Naive pluripotency is associated with global DNA hypomethylation

(2013) Harry G Leitch et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Reconciling the different roles of Gsk3β in “naïve” and “primed” pluripotent stem cells

(2012) Amar M. Singh et al.   CELL CYCLE

Epiblast Stem Cell-Based System Reveals Reprogramming Synergy of Germline Factors

(2012) Astrid Gillich et al.   Cell Stem Cell

Esrrb Is a Pivotal Target of the Gsk3/Tcf3 Axis Regulating Embryonic Stem Cell Self-Renewal

(2012) Graziano Martello et al.   Cell Stem Cell

Signaling networks in human pluripotent stem cells

(2012) Stephen Dalton   CURRENT OPINION IN CELL BIOLOGY

Directed cardiomyocyte differentiation from human pluripotent stem cells by modulating Wnt/β-catenin signaling under fully defined conditions

(2012) Xiaojun Lian et al.   Nature Protocols

Inhibition of glycogen synthase kinase-3 alleviates Tcf3 repression of the pluripotency network and increases embryonic stem cell resistance to differentiation

(2011) Jason Wray et al.   NATURE CELL BIOLOGY

The origin and identity of embryonic stem cells

(2010) J. Nichols et al.   DEVELOPMENT

edgeR: a Bioconductor package for differential expression analysis of digital gene expression data

(2009) M. D. Robinson et al.   BIOINFORMATICS

GAGE: generally applicable gene set enrichment for pathway analysis

(2009) Weijun Luo et al.   BMC BIOINFORMATICS

Naive and Primed Pluripotent States

(2009) Jennifer Nichols et al.   Cell Stem Cell

Klf4 reverts developmentally programmed restriction of ground state pluripotency

(2009) G. Guo et al.   DEVELOPMENT

Active-Site Inhibitors of mTOR Target Rapamycin-Resistant Outputs of mTORC1 and mTORC2

(2009) Morris E Feldman et al.   PLOS BIOLOGY

The ground state of embryonic stem cell self-renewal

(2008) Qi-Long Ying et al.   NATURE