The Regulation of rRNA Gene Transcription during Directed Differentiation of Human Embryonic Stem Cells

lncRNA Maturation to Initiate Heterochromatin Formation in the Nucleolus Is Required for Exit from Pluripotency in ESCs

(2014) Nataša Savić et al.   Cell Stem Cell

Downregulation of rRNA Transcription Triggers Cell Differentiation

(2014) Yuki Hayashi et al.   PLoS One

Changes in rRNA Transcription Influence Proliferation and Cell Fate Within a Stem Cell Lineage

(2014) Q. Zhang et al.   SCIENCE

Biosynthesis of Ribosomal RNA in Nucleoli Regulates Pluripotency and Differentiation Ability of Pluripotent Stem Cells

(2014) Kanako Watanabe-Susaki et al.   STEM CELLS

CX-5461 Inhibits RNA Pol I in Blood Cancers

(2014)   Cancer Discovery

NPTX1 Regulates Neural Lineage Specification from Human Pluripotent Stem Cells

(2014) Nathan C. Boles et al.   Cell Reports

Chromatin states at ribosomal DNA loci

(2013) Stephan Hamperl et al.   Biochimica et Biophysica Acta-Gene Regulatory Mechanisms

Divergent transcription of long noncoding RNA/mRNA gene pairs in embryonic stem cells

(2013) A. A. Sigova et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Efficient Generation of Astrocytes from Human Pluripotent Stem Cells in Defined Conditions

(2013) Atossa Shaltouki et al.   STEM CELLS

Differential gene and transcript expression analysis of RNA-seq experiments with TopHat and Cufflinks

(2012) Cole Trapnell et al.   Nature Protocols

Discovery of CX-5461, the First Direct and Selective Inhibitor of RNA Polymerase I, for Cancer Therapeutics

(2012) Mustapha Haddach et al.   ACS Medicinal Chemistry Letters

Control of the Embryonic Stem Cell State

(2011) Richard A. Young   CELL

Cardiopoietic Factors

(2011) Michela Noseda et al.   CIRCULATION RESEARCH

Integrative genomics viewer

(2011) James T Robinson et al.   NATURE BIOTECHNOLOGY

Integrative genomic analysis of human ribosomal DNA

(2011) Gabriel E. Zentner et al.   NUCLEIC ACIDS RESEARCH

BEDTools: a flexible suite of utilities for comparing genomic features

(2010) Aaron R. Quinlan et al.   BIOINFORMATICS

Targeting RNA Polymerase I with an Oral Small Molecule CX-5461 Inhibits Ribosomal RNA Synthesis and Solid Tumor Growth

(2010) Denis Drygin et al.   CANCER RESEARCH

The role of UBF in regulating the structure and dynamics of transcriptionally active rDNA chromatin

(2010) Elaine Sanij et al.   Epigenetics

Combined activin A/LiCl/Noggin treatment improves production of mouse embryonic stem cell-derived definitive endoderm cells

(2010) Fuming Li et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Open chromatin in pluripotency and reprogramming

(2010) Alexandre Gaspar-Maia et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

c-MYC coordinately regulates ribosomal gene chromatin remodeling and Pol I availability during granulocyte differentiation

(2010) Gretchen Poortinga et al.   NUCLEIC ACIDS RESEARCH

CTCF regulates the local epigenetic state of ribosomal DNA repeats

(2010) Suzanne van de Nobelen et al.   Epigenetics & Chromatin

Spatio-Temporal Plasticity in Chromatin Organization in Mouse Cell Differentiation and during Drosophila Embryogenesis

(2009) Dipanjan Bhattacharya et al.   BIOPHYSICAL JOURNAL

Intergenic transcripts originating from a subclass of ribosomal DNA repeats silence ribosomal RNA genes in trans

(2009) Raffaella Santoro et al.   EMBO REPORTS

Allelic inactivation of rDNA loci

(2009) S. Schlesinger et al.   GENES & DEVELOPMENT

Loss of Human Ribosomal Gene CpG Methylation Enhances Cryptic RNA Polymerase II Transcription and Disrupts Ribosomal RNA Processing

(2009) Thérèse Gagnon-Kugler et al.   MOLECULAR CELL

Promoter targeted small RNAs induce long-term transcriptional gene silencing in human cells

(2009) Peter G. Hawkins et al.   NUCLEIC ACIDS RESEARCH

The Epigenetics of rRNA Genes: From Molecular to Chromosome Biology

(2008) Brian McStay et al.   Annual Review of Cell and Developmental Biology

Global Transcription in Pluripotent Embryonic Stem Cells

(2008) Sol Efroni et al.   Cell Stem Cell

Marked differences in differentiation propensity among human embryonic stem cell lines

(2008) Kenji Osafune et al.   NATURE BIOTECHNOLOGY