Continuous precipitation of process related impurities from clarified cell culture supernatant using a novel coiled flow inversion reactor (CFIR)

Continuous viral inactivation at low pH value in antibody manufacturing

(2016) Stephan Klutz et al.   CHEMICAL ENGINEERING AND PROCESSING

Continuous refolding of a biotech therapeutic in a novel Coiled Flow Inverter Reactor

(2016) Abhishek Kumar Sharma et al.   CHEMICAL ENGINEERING SCIENCE

Continuous polyethylene glycol precipitation of recombinant antibodies: Sequential precipitation and resolubilization

(2016) Nikolaus Hammerschmidt et al.   PROCESS BIOCHEMISTRY

Capture and intermediate purification of recombinant antibodies with combined precipitation methods

(2015) Ralf Sommer et al.   BIOCHEMICAL ENGINEERING JOURNAL

Continuous downstream processing for high value biological products: A Review

(2015) Andrew L. Zydney   BIOTECHNOLOGY AND BIOENGINEERING

Development of robust antibody purification by optimizing protein-A chromatography in combination with precipitation methodologies

(2015) Srinivas Chollangi et al.   BIOTECHNOLOGY AND BIOENGINEERING

Continuous precipitation of IgG from CHO cell culture supernatant in a tubular reactor

(2015) Nikolaus Hammerschmidt et al.   Biotechnology Journal

Narrow residence time distribution in tubular reactor concept for Reynolds number range of 10–100

(2015) Stephan Klutz et al.   CHEMICAL ENGINEERING RESEARCH & DESIGN

Rapid analysis of charge variants of monoclonal antibodies using non-linear salt gradient in cation-exchange high performance liquid chromatography

(2015) Varsha Joshi et al.   JOURNAL OF CHROMATOGRAPHY A

White Paper on Continuous Bioprocessing May 20–21 2014 Continuous Manufacturing Symposium

(2015) Konstantin B. Konstantinov et al.   JOURNAL OF PHARMACEUTICAL SCIENCES

Continuous Processing for Production of Biopharmaceuticals

(2015) Anurag S. Rathore et al.   PREPARATIVE BIOCHEMISTRY & BIOTECHNOLOGY

Continuous precipitation of IgG from CHO cell culture supernatant in a tubular reactor

(2015) Nikolaus Hammerschmidt et al.   Biotechnology Journal

Perspectives on integrated continuous bioprocessing—opportunities and challenges

(2015) Andrew L Zydney   Current Opinion in Chemical Engineering

Economics of recombinant antibody production processes at various scales: Industry-standard compared to continuous precipitation

(2014) Nikolaus Hammerschmidt et al.   Biotechnology Journal

Separation of recombinant antibodies from DNA using divalent cations

(2014) Peter Satzer et al.   ENGINEERING IN LIFE SCIENCES

Ethanol precipitation for purification of recombinant antibodies

(2014) Anne Tscheliessnig et al.   JOURNAL OF BIOTECHNOLOGY

Combined polyethylene glycol and CaCl2 precipitation for the capture and purification of recombinant antibodies

(2014) Ralf Sommer et al.   PROCESS BIOCHEMISTRY

Feasibility study of semi-selective protein precipitation with salt-tolerant copolymers for industrial purification of therapeutic antibodies

(2013) Florian Capito et al.   BIOTECHNOLOGY AND BIOENGINEERING

Identification and characterization of host cell protein product-associated impurities in monoclonal antibody bioprocessing

(2013) Nicholas E. Levy et al.   BIOTECHNOLOGY AND BIOENGINEERING

Design of experiments applications in bioprocessing: Concepts and approach

(2013) Vijesh Kumar et al.   BIOTECHNOLOGY PROGRESS

Continuous downstream processing of biopharmaceuticals

(2013) Alois Jungbauer   TRENDS IN BIOTECHNOLOGY

Caprylic acid precipitation method for impurity reduction: An alternative to conventional chromatography for monoclonal antibody purification

(2012) Yan Brodsky et al.   BIOTECHNOLOGY AND BIOENGINEERING

Integrated continuous production of recombinant therapeutic proteins

(2012) Veena Warikoo et al.   BIOTECHNOLOGY AND BIOENGINEERING

Coiled flow inverter as an inline mixer

(2007) Monisha Mridha et al.   CHEMICAL ENGINEERING SCIENCE