Continuous Processing for Production of Biopharmaceuticals

Continuous protein refolding in a tubular reactor

(2014) Siqi Pan et al.   CHEMICAL ENGINEERING SCIENCE

Integrated continuous dissolution, refolding and tag removal of fusion proteins from inclusion bodies in a tubular reactor

(2014) Siqi Pan et al.   JOURNAL OF BIOTECHNOLOGY

Continuous processing of recombinant proteins: Integration of refolding and purification using simulated moving bed size-exclusion chromatography with buffer recycling

(2014) Martin Wellhoefer et al.   JOURNAL OF CHROMATOGRAPHY A

Continuous flow micro-bioreactors for the production of biopharmaceuticals: the effect of geometry, surface texture, and flow rate

(2014) Lucía D. Garza-García et al.   LAB ON A CHIP

Refolding of biotech therapeutic proteins expressed in bacteria: review

(2013) Anurag S. Rathore et al.   JOURNAL OF CHEMICAL TECHNOLOGY AND BIOTECHNOLOGY

Continuous processing of recombinant proteins: Integration of inclusion body solubilization and refolding using simulated moving bed size exclusion chromatography with buffer recycling

(2013) Martin Wellhoefer et al.   JOURNAL OF CHROMATOGRAPHY A

Continuous downstream processing of biopharmaceuticals

(2013) Alois Jungbauer   TRENDS IN BIOTECHNOLOGY

Use of focused acoustics for cell disruption to provide ultra scale-down insights of microbial homogenization and its bioprocess impact-recovery of antibody fragments from rec E. coli

(2012) Qiang Li et al.   BIOTECHNOLOGY AND BIOENGINEERING

Integrated continuous production of recombinant therapeutic proteins

(2012) Veena Warikoo et al.   BIOTECHNOLOGY AND BIOENGINEERING

Continuous purification of antibodies from cell culture supernatant with aqueous two-phase systems: From concept to process

(2012) Paula A. J. Rosa et al.   Biotechnology Journal

Optimization of a refolding step for a therapeutic fusion protein in the quality by design (QbD) paradigm

(2012) Pratap D. Bade et al.   JOURNAL OF SEPARATION SCIENCE

New integrated bioprocess for the continuous production, extraction and purification of lipopeptides produced by Bacillus subtilis in membrane bioreactor

(2012) François Coutte et al.   PROCESS BIOCHEMISTRY

Continous bioprocessing: An interview with Konstantin Konstantinov from Genzyme

(2011) Alois Jungbauer et al.   Biotechnology Journal

Countercurrent tangential chromatography for large-scale protein purification

(2010) Oleg Shinkazh et al.   BIOTECHNOLOGY AND BIOENGINEERING

Increasing the activity of monoclonal antibody therapeutics by continuous chromatography (MCSGP)

(2010) T. Müller-Späth et al.   BIOTECHNOLOGY AND BIOENGINEERING

Aqueous two-phase systems: A viable platform in the manufacturing of biopharmaceuticals

(2009) P.A.J. Rosa et al.   JOURNAL OF CHROMATOGRAPHY A

Centrifugal precipitation chromatography

(2009) Yoichiro Ito et al.   JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES

Advances in Primary Recovery: Centrifugation and Membrane Technology

(2008) D.J. Roush et al.   BIOTECHNOLOGY PROGRESS

Combination of crossflow and electric field for microfiltration of protein/microbial cell suspensions

(2008) Ching-Jung Chuang et al.   DESALINATION

High Concentration Formulations of Recombinant Human Interleukin-1 Receptor Antagonist: II. Aggregation Kinetics

(2007) John R. Alford et al.   JOURNAL OF PHARMACEUTICAL SCIENCES