Continuous precipitation of IgG from CHO cell culture supernatant in a tubular reactor

Economics of recombinant antibody production processes at various scales: Industry-standard compared to continuous precipitation

(2014) Nikolaus Hammerschmidt et al.   Biotechnology Journal

Separation of recombinant antibodies from DNA using divalent cations

(2014) Peter Satzer et al.   ENGINEERING IN LIFE SCIENCES

Ethanol precipitation for purification of recombinant antibodies

(2014) Anne Tscheliessnig et al.   JOURNAL OF BIOTECHNOLOGY

Structural Characterization of IgG1 mAb Aggregates and Particles Generated Under Various Stress Conditions

(2014) Srivalli N. Telikepalli et al.   JOURNAL OF PHARMACEUTICAL SCIENCES

Combined polyethylene glycol and CaCl2 precipitation for the capture and purification of recombinant antibodies

(2014) Ralf Sommer et al.   PROCESS BIOCHEMISTRY

Feasibility study of semi-selective protein precipitation with salt-tolerant copolymers for industrial purification of therapeutic antibodies

(2013) Florian Capito et al.   BIOTECHNOLOGY AND BIOENGINEERING

Protein a chromatography at high titers

(2013) Venkatesh Natarajan et al.   BIOTECHNOLOGY AND BIOENGINEERING

Protein crystallization in stirred systems-scale-up via the maximum local energy dissipation

(2013) Benjamin Smejkal et al.   BIOTECHNOLOGY AND BIOENGINEERING

Fast and scalable purification of a therapeutic full-length antibody based on process crystallization

(2013) Benjamin Smejkal et al.   BIOTECHNOLOGY AND BIOENGINEERING

Isolation of monoclonal antibody from a Chinese hamster ovary supernatant. I: Assessment of different separation concepts

(2013) Wojciech Marek et al.   JOURNAL OF CHROMATOGRAPHY A

Highly linear pH gradients for analyzing monoclonal antibody charge heterogeneity in the alkaline range

(2013) Nico Lingg et al.   JOURNAL OF CHROMATOGRAPHY A

Monoclonal antibody capture and viral clearance by cation exchange chromatography

(2012) G.R. Miesegaes et al.   BIOTECHNOLOGY AND BIOENGINEERING

Integrated continuous production of recombinant therapeutic proteins

(2012) Veena Warikoo et al.   BIOTECHNOLOGY AND BIOENGINEERING

A new large-scale manufacturing platform for complex biopharmaceuticals

(2012) Jens H. Vogel et al.   BIOTECHNOLOGY AND BIOENGINEERING

Periodic counter-current chromatography - design and operational considerations for integrated and continuous purification of proteins

(2012) Rahul Godawat et al.   Biotechnology Journal

State-of-the-art in downstream processing of monoclonal antibodies: Process trends in design and validation

(2012) P. A. Marichal-Gallardo et al.   BIOTECHNOLOGY PROGRESS

Improving affinity chromatography resin efficiency using semi-continuous chromatography

(2012) Ekta Mahajan et al.   JOURNAL OF CHROMATOGRAPHY A

An innovative approach for the characterization of the isoforms of a monoclonal antibody product

(2012) Shanmuuga Sundaram et al.   mAbs

Bioinspired and sustainable chitosan-based monoliths for antibody capture and release

(2012) Telma Barroso et al.   RSC Advances

Continuous aqueous two-phase extraction of human antibodies using a packed column

(2011) P.A.J. Rosa et al.   JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES

A single-use purification process for the production of a monoclonal antibody produced in a PER.C6 human cell line

(2010) Michael Kuczewski et al.   Biotechnology Journal

Maximizing productivity of CHO cell-based fed-batch culture using chemically defined media conditions and typical manufacturing equipment

(2010) Yao-Ming Huang et al.   BIOTECHNOLOGY PROGRESS

Industrialization of mAb production technology: The bioprocessing industry at a crossroads

(2010) Brian Kelley   mAbs

Selective antibody precipitation using polyelectrolytes: A novel approach to the purification of monoclonal antibodies

(2008) Paul McDonald et al.   BIOTECHNOLOGY AND BIOENGINEERING

Integrated process for the purification of antibodies combining aqueous two-phase extraction, hydrophobic interaction chromatography and size-exclusion chromatography

(2008) A.M. Azevedo et al.   JOURNAL OF CHROMATOGRAPHY A

High-performance monolith affinity chromatography for fast quantitation of immunoglobulin G

(2008) Anne Tscheliessnig et al.   JOURNAL OF CHROMATOGRAPHY A

Heterogeneity of Monoclonal Antibodies

(2007) Hongcheng Liu et al.   JOURNAL OF PHARMACEUTICAL SCIENCES