Artemether Activation of AMPK/GSK3β(ser9)/Nrf2 Signaling Confers Neuroprotection towards β-Amyloid-Induced Neurotoxicity in 3xTg Alzheimer’s Mouse Model

Natural or Plant Products for the Treatment of Neurological Disorders: Current Knowledge

(2018) Mohammad Khalid Parvez   CURRENT DRUG METABOLISM

Berberine Protects Human Retinal Pigment Epithelial Cells from Hydrogen Peroxide-Induced Oxidative Damage through Activation of AMPK

(2018) Shuai Li et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Dihydroartemisinin alleviates oxidative stress in bleomycin-induced pulmonary fibrosis

(2018) Dong-xia Yang et al.   LIFE SCIENCES

Artesunate suppresses oxidative and inflammatory processes by activating Nrf2 and ROS‑dependent p38 MAPK and protects against cerebral ischemia‑reperfusion injury

(2018) Hui Lu et al.   Molecular Medicine Reports

Synaptic dysfunction in Alzheimer's disease: the effects of amyloid beta on synaptic vesicle dynamics as a novel target for therapeutic intervention

(2018) Pavlos Alifragis et al.   Neural Regeneration Research

Amentoflavone Ameliorates Aβ1–42-Induced Memory Deficits and Oxidative Stress in Cellular and Rat Model

(2018) Chao Chen et al.   NEUROCHEMICAL RESEARCH

Reactive astrocytes in Alzheimer’s disease: A double-edged sword

(2018) Heejung Chun et al.   NEUROSCIENCE RESEARCH

Targeting Nrf2 to Suppress Ferroptosis and Mitochondrial Dysfunction in Neurodegeneration

(2018) Moataz Abdalkader et al.   Frontiers in Neuroscience

Pharmacological targeting of GSK-3 and NRF2 provides neuroprotection in a preclinical model of tauopathy

(2018) Antonio Cuadrado et al.   Redox Biology

Tanshinone IIA Attenuates Insulin Like Growth Factor 1 -Induced Cell Proliferation in PC12 Cells through the PI3K/Akt and MEK/ERK Pathways

(2018) Haitao Wang et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Increased Permeability of the Blood-Brain Barrier and Alzheimer's Disease-Like Alterations in Slit-2 Transgenic Mice

(2018) Jiang-chao Li et al.   JOURNAL OF ALZHEIMERS DISEASE

Oxidative Stress, Synaptic Dysfunction, and Alzheimer’s Disease

(2017) Eric Tönnies et al.   JOURNAL OF ALZHEIMERS DISEASE

Role of brain-derived neurotrophic factor and nerve growth factor in the regulation of Neuropeptide W in vitro and in vivo

(2017) Rikang Wang et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Artemisinin protects PC12 cells against β-amyloid-induced apoptosis through activation of the ERK1/2 signaling pathway

(2017) Zhiwen Zeng et al.   Redox Biology

Artemisinin conferred ERK mediated neuroprotection to PC12 cells and cortical neurons exposed to sodium nitroprusside-induced oxidative insult

(2016) Wenhua Zheng et al.   FREE RADICAL BIOLOGY AND MEDICINE

AMPK Facilitates Nuclear Accumulation of Nrf2 by Phosphorylating at Serine 550

(2016) Min Sung Joo et al.   MOLECULAR AND CELLULAR BIOLOGY

Artemisinin protects human retinal pigment epithelial cells from hydrogen peroxide-induced oxidative damage through activation of ERK/CREB signaling

(2016) Cheong-Meng Chong et al.   Redox Biology

Nobiletin, a citrus flavonoid, improves cognitive impairment and reduces soluble Aβ levels in a triple transgenic mouse model of Alzheimer's disease (3XTg-AD)

(2015) Akira Nakajima et al.   BEHAVIOURAL BRAIN RESEARCH

Nrf2—a therapeutic target for the treatment of neurodegenerative diseases

(2015) Delinda A. Johnson et al.   FREE RADICAL BIOLOGY AND MEDICINE

Oxidative Stress Is a Central Target for Physical Exercise Neuroprotection Against Pathological Brain Aging

(2015) Yoelvis García-Mesa et al.   JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES

Anti-Inflammatory and Immunoregulatory Functions of Artemisinin and Its Derivatives

(2015) Chenchen Shi et al.   MEDIATORS OF INFLAMMATION

Antimalarial Drug Artemether Inhibits Neuroinflammation in BV2 Microglia Through Nrf2-Dependent Mechanisms

(2015) Uchechukwu P. Okorji et al.   MOLECULAR NEUROBIOLOGY

Gracilins: Spongionella-derived promising compounds for Alzheimer disease

(2015) Marta Leirós et al.   NEUROPHARMACOLOGY

Glycogen synthase kinase-3 (GSK3): Regulation, actions, and diseases

(2015) Eleonore Beurel et al.   PHARMACOLOGY & THERAPEUTICS

Amyloid beta receptors responsible for neurotoxicity and cellular defects in Alzheimer’s disease

(2014) Tae-In Kam et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

The AMPK Inhibitor Compound C Is a Potent AMPK-Independent Antiglioma Agent

(2014) X. Liu et al.   MOLECULAR CANCER THERAPEUTICS

Psychopharmacology of atypical antipsychotic drugs: From the receptor binding profile to neuroprotection and neurogenesis

(2014) Ichiro Kusumi et al.   PSYCHIATRY AND CLINICAL NEUROSCIENCES

Antimicrobial Activity of Artemisinin and Precursor Derived fromIn VitroPlantlets ofArtemisia annuaL.

(2014) Suganthi Appalasamy et al.   Biomed Research International

Neurotransmitters and Microglial-Mediated Neuroinflammation

(2013) Moonhee Lee   CURRENT PROTEIN & PEPTIDE SCIENCE

The Beneficial Effect of Ginsenoside Rg1 on Schwann Cells Subjected to Hydrogen Peroxide Induced Oxidative Injury

(2013) Junxiong Ma et al.   International Journal of Biological Sciences

Roles of AMP-activated Protein Kinase in Alzheimer’s Disease

(2012) Zhiyou Cai et al.   NEUROMOLECULAR MEDICINE

Multi-Target Drugs: The Trend of Drug Research and Development

(2012) Jin-Jian Lu et al.   PLoS One

Multi-Target-Directed Ligands in Alzheimer's Disease Treatment

(2011) M. Bajda et al.   CURRENT MEDICINAL CHEMISTRY

Antitumor Activity of Artemisinin and Its Derivatives: From a Well-Known Antimalarial Agent to a Potential Anticancer Drug

(2011) Maria P. Crespo-Ortiz et al.   JOURNAL OF BIOMEDICINE AND BIOTECHNOLOGY

GFAP in health and disease

(2011) J. Middeldorp et al.   PROGRESS IN NEUROBIOLOGY

AMPK is abnormally activated in tangle- and pre-tangle-bearing neurons in Alzheimer’s disease and other tauopathies

(2010) Valérie Vingtdeux et al.   ACTA NEUROPATHOLOGICA

Role of microglial redox balance in modulation of neuroinflammation

(2009) Nadia G Innamorato et al.   CURRENT OPINION IN NEUROLOGY

Discovery, mechanisms of action and combination therapy of artemisinin

(2009) Liwang Cui et al.   Expert Review of Anti-Infective Therapy

Inhibitive Effect of Artemether on Tumor Growth and Angiogenesis in the Rat C6 Orthotopic Brain Gliomas Model

(2009) Zhi-ping Wu et al.   INTEGRATIVE CANCER THERAPIES

Artemisinin Resistance inPlasmodium falciparumMalaria

(2009) Arjen M. Dondorp et al.   NEW ENGLAND JOURNAL OF MEDICINE

Detailed immunohistochemical characterization of temporal and spatial progression of Alzheimer's disease-related pathologies in male triple-transgenic mice

(2008) Michael A Mastrangelo et al.   BMC NEUROSCIENCE

Ibuprofen reduces Aβ, hyperphosphorylated tau and memory deficits in Alzheimer mice

(2008) Ann C. McKee et al.   BRAIN RESEARCH

Oxidative stress induces macroautophagy of amyloid β-protein and ensuing apoptosis

(2008) Lin Zheng et al.   FREE RADICAL BIOLOGY AND MEDICINE

Antioxidant Therapy in Alzheimers Disease: Theory and Practice

(2008) Gjumrakch Aliev et al.   MINI-REVIEWS IN MEDICINAL CHEMISTRY

Mechanisms of Aβ mediated neurodegeneration in Alzheimer's disease

(2007) Peter J. Crouch et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY