Multi-Target Drugs: The Trend of Drug Research and Development

Targeting Strategies for Human Immunodeficiency Virus: A Combinatorial Approach

(2012) S. K. Saxena et al.   MINI-REVIEWS IN MEDICINAL CHEMISTRY

Applications of metabolomics for understanding the action of peroxisome proliferator-activated receptors (PPARs) in diabetes, obesity and cancer

(2012) Zsuzsanna Ament et al.   Genome Medicine

Peroxisome Proliferator-Activated Receptors and Atherosclerosis

(2011) Sanja S. Soskić et al.   ANGIOLOGY

Focal Adhesion Kinase as a Cancer Therapy Target

(2011) Vita M. Golubovskaya   Anti-Cancer Agents in Medicinal Chemistry

Discovery of curcumin, a component of golden spice, and its miraculous biological activities

(2011) Subash C Gupta et al.   CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY

Monoamine Oxidase B Inhibitors for the Treatment of Parkinsonʼs Disease

(2011) Anthony H.V. Schapira   CNS DRUGS

Utility of Atherosclerosis Imaging in the Evaluation of High-Density Lipoprotein–Raising Therapies

(2011) Raphaël Duivenvoorden et al.   Current Atherosclerosis Reports

Cyclooxygenase as a Target for Colorectal Cancer Chemoprevention

(2011) Leticia Moreira et al.   CURRENT DRUG TARGETS

Combination Therapy for Alzheimerʼs Disease

(2011) Laxeshkumar Patel et al.   DRUGS & AGING

The Lectin-Like Oxidized Low-Density Lipoprotein Receptor-1 and its Soluble Form: Cardiovascular Implications

(2011) Teresa Navarra et al.   Journal of Atherosclerosis and Thrombosis

Combinatorial Effect of Probucol and Cilostazol in Focal Ischemic Mice with Hypercholesterolemia

(2011) J. H. Kim et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

Multitargeting by curcumin as revealed by molecular interaction studies

(2011) Subash C. Gupta et al.   NATURAL PRODUCT REPORTS

Current Status of Src Inhibitors in Solid Tumor Malignancies

(2011) L. N. Puls et al.   ONCOLOGIST

Targeting EGFR in non-small-cell lung cancer: Lessons, experiences, strategies

(2011) Giulia M. Stella et al.   RESPIRATORY MEDICINE

Anti-cancer natural products isolated from chinese medicinal herbs

(2011) Wen Tan et al.   Chinese Medicine

Regulation of survival, proliferation, invasion, angiogenesis, and metastasis of tumor cells through modulation of inflammatory pathways by nutraceuticals

(2010) Subash C. Gupta et al.   CANCER AND METASTASIS REVIEWS

The mTOR Pathway: A New Target in Cancer Therapy

(2010) L. Ciuffreda et al.   CURRENT CANCER DRUG TARGETS

The PI3K Pathway As Drug Target in Human Cancer

(2010) Kevin D. Courtney et al.   JOURNAL OF CLINICAL ONCOLOGY

Baicalin, an emerging multi-therapeutic agent: pharmacodynamics, pharmacokinetics, and considerations from drug development perspectives

(2010) N. R. Srinivas   XENOBIOTICA

A systematic review of the anticancer properties of berberine, a natural product from Chinese herbs

(2009) Yiyi Sun et al.   ANTI-CANCER DRUGS

Design, synthesis and biological evaluation of novel dual inhibitors of acetylcholinesterase and β-secretase

(2009) Yiping Zhu et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Tubulin: A Target for Antineoplastic Drugs into the Cancer Cells but also in the Peripheral Nervous System

(2009) Annalisa Canta et al.   CURRENT MEDICINAL CHEMISTRY

Multifocal signal modulation therapy of cancer: ancient weapon, modern targets

(2009) Tanya Das et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

Hyperphosphorylation of Microtubule-Associated Protein Tau: A Promising Therapeutic Target for Alzheimer Disease

(2008) C.-X. Gong et al.   CURRENT MEDICINAL CHEMISTRY

From Single- to Multi-Target Drugs in Cancer Therapy: When Aspecificity Becomes an Advantage

(2008) S. Giordano et al.   CURRENT MEDICINAL CHEMISTRY

Natural products in drug discovery

(2008) A HARVEY   DRUG DISCOVERY TODAY

Nilotinib: a phenylamino-pyrimidine derivative with activity against BCR-ABL, KIT and PDGFR kinases

(2008) Alfonso Quintás-Cardama et al.   Future Oncology

Combined R-α-lipoic acid and acetyl-L-carnitine exerts efficient preventative effects in a cellular model of Parkinson’s disease

(2008) Hongyu Zhang et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Discovery of Multitarget Inhibitors by Combining Molecular Docking with Common Pharmacophore Matching

(2008) Dengguo Wei et al.   JOURNAL OF MEDICINAL CHEMISTRY

Histone Deacetylation

(2008) Anas Al-Janadi et al.   Drugs in research & development