Psychopharmacology of atypical antipsychotic drugs: From the receptor binding profile to neuroprotection and neurogenesis

Improving the Treatment of Schizophrenia: Role of 5-HT Receptors in Modulating Cognitive and Extrapyramidal Motor Functions

(2013) Saki Shimizu et al.   CNS & Neurological Disorders-Drug Targets

Valproate recovers the inhibitory effect of dexamethasone on the proliferation of the adult dentate gyrus-derived neural precursor cells via GSK-3β and β-catenin pathway

(2013) Shuken Boku et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Dopamine D3 receptor antagonism—still a therapeutic option for the treatment of schizophrenia

(2013) Gerhard Gross et al.   NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY

Neural Basis for the Ability of Atypical Antipsychotic Drugs to Improve Cognition in Schizophrenia

(2013) Tomiki Sumiyoshi et al.   Frontiers in Behavioral Neuroscience

Serotonin Receptors as Targets for Drugs Useful to Treat Psychosis and Cognitive Impairment in Schizophrenia

(2012) H. Y. Meltzer et al.   CURRENT PHARMACEUTICAL BIOTECHNOLOGY

Pharmacological treatment of schizophrenia: a critical review of the pharmacology and clinical effects of current and future therapeutic agents

(2012) S Miyamoto et al.   MOLECULAR PSYCHIATRY

Serotonin–glutamate and serotonin–dopamine reciprocal interactions as putative molecular targets for novel antipsychotic treatments: from receptor heterodimers to postsynaptic scaffolding and effector proteins

(2012) A. de Bartolomeis et al.   PSYCHOPHARMACOLOGY

Effects of 5-HT6 antagonists, Ro-4368554 and SB-258585, in tests used for the detection of cognitive enhancement and antipsychotic-like activity

(2011) Andreas Gravius et al.   BEHAVIOURAL PHARMACOLOGY

Effects of risperidone treatment in adolescence on hippocampal neurogenesis, parvalbumin expression, and vascularization following prenatal immune activation in rats

(2011) Yael Piontkewitz et al.   BRAIN BEHAVIOR AND IMMUNITY

Glycogen synthase kinase 3β inhibitors protect hippocampal neurons from radiation-induced apoptosis by regulating MDM2-p53 pathway

(2011) D K Thotala et al.   CELL DEATH AND DIFFERENTIATION

Functional significance of glycogen synthase kinase-3 regulation by serotonin

(2011) Abigail M. Polter et al.   CELLULAR SIGNALLING

5-HT1A Receptor Agonists Enhance Pyramidal Cell Firing in Prefrontal Cortex Through a Preferential Action on GABA Interneurons

(2011) L. Llado-Pelfort et al.   CEREBRAL CORTEX

Phosphorylation of Akt/GSK-3β/eNOS amplifies 5-HT2Breceptor blockade mediated anti-hypertrophic effect in rats

(2011) Saurabh Bharti et al.   FEBS LETTERS

Noradrenaline increases neural precursor cells derived from adult rat dentate gyrus through beta2 receptor

(2011) Takahiro Masuda et al.   PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY

The role of serotonin in the NMDA receptor antagonist models of psychosis and cognitive impairment

(2011) Herbert Y. Meltzer et al.   PSYCHOPHARMACOLOGY

Glycogen Synthase Kinase-3 is an Intermediate Modulator of Serotonin Neurotransmission

(2011) Abigail M. Polter et al.   Frontiers in Molecular Neuroscience

Antipsychotic Medication: The Potential Role of 5-HT1A Receptor Agonism

(2010) Andrew McCreary et al.   CURRENT PHARMACEUTICAL DESIGN

Lu AE58054, a 5-HT6 antagonist, reverses cognitive impairment induced by subchronic phencyclidine in a novel object recognition test in rats

(2010) Jorn Arnt et al.   INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY

Serotonergic modulation of extrapyramidal motor disorders in mice and rats: Role of striatal 5-HT3 and 5-HT6 receptors

(2010) Yukihiro Ohno et al.   NEUROPHARMACOLOGY

Implications of animal object memory research for human amnesia

(2010) Boyer D. Winters et al.   NEUROPSYCHOLOGIA

Kainic acid-induced seizures activate GSK-3β in the hippocampus of D2R−/− mice

(2010) Prem P. Tripathi et al.   NEUROREPORT

Effects of aripiprazole and haloperidol on progression to schizophrenia-like behavioural abnormalities and apoptosis in rodents

(2010) Tomohiro Abekawa et al.   SCHIZOPHRENIA RESEARCH

Dysregulation of kisspeptin and neurogenesis at adolescence link inborn immune deficits to the late onset of abnormal sensorimotor gating in congenital psychological disorders

(2009) M Cardon et al.   MOLECULAR PSYCHIATRY

Amisulpride is a potent 5-HT7 antagonist: relevance for antidepressant actions in vivo

(2009) Atheir I. Abbas et al.   PSYCHOPHARMACOLOGY

DRD3, but not COMT or DRD2, genotype affects executive functions in healthy and first-episode psychosis adolescents

(2008) Igor Bombin et al.   AMERICAN JOURNAL OF MEDICAL GENETICS PART B-NEUROPSYCHIATRIC GENETICS

The Dopamine D3 Receptor Ser9Gly Polymorphism Modulates Prepulse Inhibition of the Acoustic Startle Reflex

(2008) Panos Roussos et al.   BIOLOGICAL PSYCHIATRY

Differential Modulation of Akt/Glycogen Synthase Kinase-3β Pathway Regulates Apoptotic and Cytoprotective Signaling Responses

(2008) Venugopalan D. Nair et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Second-generation versus first-generation antipsychotic drugs for schizophrenia: a meta-analysis

(2008) Stefan Leucht et al.   LANCET

Transcriptional control of human p53-regulated genes

(2008) Todd Riley et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Glucocorticoids and Lithium Reciprocally Regulate the Proliferation of Adult Dentate Gyrus-Derived Neural Precursor Cells Through GSK-3β and β-Catenin/TCF Pathway

(2008) Shuken Boku et al.   NEUROPSYCHOPHARMACOLOGY

5-HT2A/2C receptor blockade regulates progenitor cell proliferation in the adult rat hippocampus

(2008) Shanker Jha et al.   NEUROSCIENCE LETTERS

Antipsychotic-Induced Hyperprolactinemia

(2008) Jolene R Bostwick et al.   PHARMACOTHERAPY

Olanzapine and risperidone block a high dose of methamphetamine-induced schizophrenia-like behavioral abnormalities and accompanied apoptosis in the medial prefrontal cortex

(2008) Tomohiro Abekawa et al.   SCHIZOPHRENIA RESEARCH

The selective 5-HT6 receptor antagonist Ro 04-6790 attenuates psychotomimetic effects of the NMDA receptor antagonist MK-801

(2007) N PITSIKAS   BEHAVIOURAL BRAIN RESEARCH

Long-term perospirone treatment with a single dose at bedtime in schizophrenia: Relevant to intermittent dopamine D2 receptor antagonism

(2007) Ichiro Kusumi et al.   PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY

Protective effects of olanzapine and haloperidol on serum withdrawal-induced apoptosis in SH-SY5Y cells

(2007) Na Ri Kim et al.   PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY

Haloperidol-Induced Neuronal Apoptosis

(2003) Jai Sung Noh et al.   JOURNAL OF NEUROCHEMISTRY