The future of rodent models in depression research

Loss of Environmental Enrichment Elicits Behavioral and Physiological Dysregulation in Female Rats

(2019) Rachel Morano et al.   Frontiers in Behavioral Neuroscience

Evaluating the evidence for biotypes of depression: Methodological replication and extension of

(2019) Richard Dinga et al.   NeuroImage-Clinical

The genetics of depression: successful genome-wide association studies introduce new challenges

(2019) Johan Ormel et al.   Translational Psychiatry

Gut Microbe to Brain Signaling: What Happens in Vagus…

(2019) Christine Fülling et al.   NEURON

Genome-wide meta-analysis of depression identifies 102 independent variants and highlights the importance of the prefrontal brain regions

(2019) David M. Howard et al.   NATURE NEUROSCIENCE

Resilience to chronic stress is associated with specific neurobiological, neuroendocrine and immune responses

(2019) Anand Gururajan et al.   BRAIN BEHAVIOR AND IMMUNITY

The critical importance of basic animal research for neuropsychiatric disorders

(2019) Tracy L. Bale et al.   NEUROPSYCHOPHARMACOLOGY

Depression researchers rethink popular mouse swim tests

(2019) Sara Reardon   NATURE

Are hormones a “female problem” for animal research?

(2019) Rebecca M. Shansky   SCIENCE

Stress-Induced Depression: Is Social Rank a Predictive Risk Factor?

(2018) Thomas Larrieu et al.   BIOESSAYS

Animal Models of Addiction and Neuropsychiatric Disorders and Their Role in Drug Discovery: Honoring the Legacy of Athina Markou

(2018) Paul J. Kenny et al.   BIOLOGICAL PSYCHIATRY

The Lateral Habenula Directs Coping Styles Under Conditions of Stress Via Recruitment of the Endocannabinoid System

(2018) Anthony L. Berger et al.   BIOLOGICAL PSYCHIATRY

Essential Role of Ovarian Hormones in Susceptibility to the Consequences of Witnessing Social Defeat in Female Rats

(2018) Julie E. Finnell et al.   BIOLOGICAL PSYCHIATRY

Meeting Report: Can We Make Animal Models of Human Mental Illness?

(2018) Lisa M. Monteggia et al.   BIOLOGICAL PSYCHIATRY

Parental Advisory: Maternal and Paternal Stress Can Impact Offspring Neurodevelopment

(2018) Jennifer C Chan et al.   BIOLOGICAL PSYCHIATRY

Estimation of clinical trial success rates and related parameters

(2018) Chi Heem Wong et al.   BIOSTATISTICS

Brain-wide Electrical Spatiotemporal Dynamics Encode Depression Vulnerability

(2018) Rainbo Hultman et al.   CELL

Common Disease Is More Complex Than Implied by the Core Gene Omnigenic Model

(2018) Naomi R. Wray et al.   CELL

miR-214-3p Targets β-Catenin to Regulate Depressive-like Behaviors Induced by Chronic Social Defeat Stress in Mice

(2018) Zhi-Fang Deng et al.   CEREBRAL CORTEX

Behavioural and neural sequelae of stressor exposure are not modulated by controllability in females

(2018) Michael V. Baratta et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Long Noncoding RNA-Associated Transcriptomic Changes in Resiliency or Susceptibility to Depression and Response to Antidepressant Treatment

(2018) Bhaskar Roy et al.   INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY

Relevance of Rodent Models of Depression in Clinical Practice: Can We Overcome the Obstacles in Translational Neuropsychiatry?

(2018) Johan Söderlund et al.   INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY

Corticosterone Production during Repeated Social Defeat Causes Monocyte Mobilization from the Bone Marrow, Glucocorticoid Resistance, and Neurovascular Adhesion Molecule Expression

(2018) Anzela Niraula et al.   JOURNAL OF NEUROSCIENCE

Comparative efficacy and acceptability of 21 antidepressant drugs for the acute treatment of adults with major depressive disorder: a systematic review and network meta-analysis

(2018) Andrea Cipriani et al.   LANCET

Computational psychiatry: a report from the 2017 NIMH workshop on opportunities and challenges

(2018) Michele Ferrante et al.   MOLECULAR PSYCHIATRY

Genome-wide association analyses identify 44 risk variants and refine the genetic architecture of major depression

(2018) Naomi R. Wray et al.   NATURE GENETICS

Insular cortex mediates approach and avoidance responses to social affective stimuli

(2018) Morgan M. Rogers-Carter et al.   NATURE NEUROSCIENCE

Social transmission and buffering of synaptic changes after stress

(2018) Toni-Lee Sterley et al.   NATURE NEUROSCIENCE

Genetic Dissection of Neural Circuits: A Decade of Progress

(2018) Liqun Luo et al.   NEURON

Perinatal fluoxetine prevents the effect of pre-gestational maternal stress on 5-HT in the PFC, but maternal stress has enduring effects on mPFC synaptic structure in offspring

(2018) Mary Gemmel et al.   NEUROPHARMACOLOGY

Response to therapeutic sleep deprivation: a naturalistic study of clinical and genetic factors and post-treatment depressive symptom trajectory

(2018) Nina Trautmann et al.   NEUROPSYCHOPHARMACOLOGY

Sex differences in antidepressant efficacy

(2018) Tara A. LeGates et al.   NEUROPSYCHOPHARMACOLOGY

Effects of light and dark phase testing on the investigation of behavioural paradigms in mice: Relevance for behavioural neuroscience

(2018) Juliet Richetto et al.   PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR

Reproducibility and replicability in zebrafish behavioral neuroscience research

(2018) Robert Gerlai   PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR

Selective effects of 5-HT2C receptor modulation on performance of a novel valence-probe visual discrimination task and probabilistic reversal learning in mice

(2018) Benjamin U. Phillips et al.   PSYCHOPHARMACOLOGY

Acute stress evokes sexually dimorphic, stressor-specific patterns of neural activation across multiple limbic brain regions in adult rats

(2018) Ankit Sood et al.   STRESS-THE INTERNATIONAL JOURNAL ON THE BIOLOGY OF STRESS

RNA-Dependent Intergenerational Inheritance of Enhanced Synaptic Plasticity after Environmental Enrichment

(2018) Eva Benito et al.   Cell Reports

HCN2 channels in the ventral tegmental area regulate behavioral responses to chronic stress

(2018) Peng Zhong et al.   eLife

The Exposome Paradigm and the Complexities of Environmental Research in Psychiatry

(2018) Sinan Guloksuz et al.   JAMA Psychiatry

The mouse as a model for neuropsychiatric drug development

(2018) James R. Howe et al.   CURRENT BIOLOGY

DeepLabCut: markerless pose estimation of user-defined body parts with deep learning

(2018) Alexander Mathis et al.   NATURE NEUROSCIENCE

Maternal immune activation: reporting guidelines to improve the rigor, reproducibility, and transparency of the model

(2018) Amanda C. Kentner et al.   NEUROPSYCHOPHARMACOLOGY

Early life stress leads to sex differences in development of depressive-like outcomes in a mouse model

(2018) Haley L. Goodwill et al.   NEUROPSYCHOPHARMACOLOGY

NOP agonists prevent the antidepressant-like effects of nortriptyline and fluoxetine but not R-ketamine

(2018) Victor A. D. Holanda et al.   PSYCHOPHARMACOLOGY

A critical view on transgenerational epigenetic inheritance in humans

(2018) Bernhard Horsthemke   Nature Communications

Early Life Stress in Rodents: Animal Models of Illness or Resilience?

(2018) Sahana Murthy et al.   Frontiers in Behavioral Neuroscience

Resilience priming: Translational models for understanding resiliency and adaptation to early life adversity

(2018) Amanda C. Kentner et al.   DEVELOPMENTAL PSYCHOBIOLOGY

Perinatal exposure to the SSRI paroxetine alters the methylome landscape of the developing dentate gyrus

(2018) Matthew E. Glover et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Global, regional, and national incidence, prevalence, and years lived with disability for 354 diseases and injuries for 195 countries and territories, 1990–2017: a systematic analysis for the Global Burden of Disease Study 2017

(2018) Spencer L James et al.   LANCET

Comparing phenotypic variation between inbred and outbred mice

(2018) Alexander H. Tuttle et al.   NATURE METHODS

Wiring the depressed brain: optogenetic and chemogenetic circuit interrogation in animal models of depression

(2018) Jessie Muir et al.   NEUROPSYCHOPHARMACOLOGY

GABA-modulating bacteria of the human gut microbiota

(2018) Philip Strandwitz et al.   Nature Microbiology

Chronic corticosterone administration effects on behavioral emotionality in female c57bl6 mice.

(2017) Maryam Mekiri et al.   EXPERIMENTAL AND CLINICAL PSYCHOPHARMACOLOGY

Decreased Nucleus Accumbens Expression of Psychiatric Disorder Risk Gene Cacna1c Promotes Susceptibility to Social Stress

(2017) Chantelle E. Terrillion et al.   INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY

Management of Depression in Older Adults

(2017) Rob M. Kok et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Effects of Chronic Social Defeat Stress on Sleep and Circadian Rhythms Are Mitigated by Kappa-Opioid Receptor Antagonism

(2017) Audrey M. Wells et al.   JOURNAL OF NEUROSCIENCE

Sex-specific transcriptional signatures in human depression

(2017) Benoit Labonté et al.   NATURE MEDICINE

A guide to designing germline-dependent epigenetic inheritance experiments in mammals

(2017) Johannes Bohacek et al.   NATURE METHODS

Network neuroscience

(2017) Danielle S Bassett et al.   NATURE NEUROSCIENCE

Social stress induces neurovascular pathology promoting depression

(2017) Caroline Menard et al.   NATURE NEUROSCIENCE

Brain–gut–microbiota axis — mood, metabolism and behaviour

(2017) Timothy G. Dinan et al.   Nature Reviews Gastroenterology & Hepatology

Neuroscience Needs Behavior: Correcting a Reductionist Bias

(2017) John W. Krakauer et al.   NEURON

In Vivo Fiber Photometry Reveals Signature of Future Stress Susceptibility in Nucleus Accumbens

(2017) Jessie Muir et al.   NEUROPSYCHOPHARMACOLOGY

A Novel Method for Chronic Social Defeat Stress in Female Mice

(2017) Alexander Z Harris et al.   NEUROPSYCHOPHARMACOLOGY

Social instability stress in adolescent male rats reduces social interaction and social recognition performance and increases oxytocin receptor binding

(2017) Travis E. Hodges et al.   NEUROSCIENCE

Mouse Phenome Database: an integrative database and analysis suite for curated empirical phenotype data from laboratory mice

(2017) Molly A Bogue et al.   NUCLEIC ACIDS RESEARCH

Probiotic treatment reduces depressive-like behaviour in rats independently of diet

(2017) Anders Abildgaard et al.   PSYCHONEUROENDOCRINOLOGY

Behavioral and physiological consequences of enrichment loss in rats

(2017) Brittany L. Smith et al.   PSYCHONEUROENDOCRINOLOGY

An adverse early life environment can enhance stress resilience in adulthood

(2017) Sara Santarelli et al.   PSYCHONEUROENDOCRINOLOGY

Perinatal fluoxetine effects on social play, the HPA system, and hippocampal plasticity in pre-adolescent male and female rats: Interactions with pre-gestational maternal stress

(2017) Mary Gemmel et al.   PSYCHONEUROENDOCRINOLOGY

Further validation of the affective bias test for predicting antidepressant and pro-depressant risk: effects of pharmacological and social manipulations in male and female rats

(2017) Justyna K. Hinchcliffe et al.   PSYCHOPHARMACOLOGY

Early life stress confers lifelong stress susceptibility in mice via ventral tegmental area OTX2

(2017) Catherine J. Peña et al.   SCIENCE

Hippocampal extracellular matrix alterations contribute to cognitive impairment associated with a chronic depressive-like state in rats

(2017) Danai Riga et al.   Science Translational Medicine

The behavioral and molecular evaluation of effects of social instability stress as a model of stress-related disorders in adult female rats

(2017) Marta Maria Nowacka-Chmielewska et al.   STRESS-THE INTERNATIONAL JOURNAL ON THE BIOLOGY OF STRESS

Stress during pregnancy alters temporal and spatial dynamics of the maternal and offspring microbiome in a sex-specific manner

(2017) Eldin Jašarević et al.   Scientific Reports

The effects of probiotics on depressive symptoms in humans: a systematic review

(2017) Caroline J. K. Wallace et al.   Annals of General Psychiatry

Neuroscience in the third dimension: shedding new light on the brain with tissue clearing

(2017) Robin J. Vigouroux et al.   Molecular Brain

Toward an Evidence-Based, Operational Definition of Treatment-Resistant Depression

(2017) Charles R. Conway et al.   JAMA Psychiatry

A continuum of genetic liability for minor and major depression

(2017) E C Corfield et al.   Translational Psychiatry

Common Marmosets: A Potential Translational Animal Model of Juvenile Depression

(2017) Nicole Leite Galvão-Coelho et al.   Frontiers in Psychiatry

Physical versus psychological social stress in male rats reveals distinct cardiovascular, inflammatory and behavioral consequences

(2017) Julie E. Finnell et al.   PLoS One

Establishment of a repeated social defeat stress model in female mice

(2017) Aki Takahashi et al.   Scientific Reports

Heritability of major depressive and comorbid anxiety disorders in multi-generational families at high risk for depression

(2016) Guia Guffanti et al.   AMERICAN JOURNAL OF MEDICAL GENETICS PART B-NEUROPSYCHIATRIC GENETICS

The Phenomenology of Major Depression and the Representativeness and Nature of DSM Criteria

(2016) Kenneth S. Kendler   AMERICAN JOURNAL OF PSYCHIATRY

A gut (microbiome) feeling about the brain

(2016) Eoin Sherwin et al.   CURRENT OPINION IN GASTROENTEROLOGY

Effects of levomilnacipran extended-release on motivation/energy and functioning in adults with major depressive disorder

(2016) Michael E. Thase et al.   INTERNATIONAL CLINICAL PSYCHOPHARMACOLOGY

Associations between depression and specific childhood experiences of abuse and neglect: A meta-analysis

(2016) Maria Rita Infurna et al.   JOURNAL OF AFFECTIVE DISORDERS

Transferring the blues: Depression-associated gut microbiota induces neurobehavioural changes in the rat

(2016) John R. Kelly et al.   JOURNAL OF PSYCHIATRIC RESEARCH

Transgenerational disruption of functional 5-HT1AR-induced connectivity in the adult mouse brain by traumatic stress in early life

(2016) F Razoux et al.   MOLECULAR PSYCHIATRY

Microbiome: Bacterial broadband

(2016) Michael Eisenstein   NATURE

NMDAR inhibition-independent antidepressant actions of ketamine metabolites

(2016) Panos Zanos et al.   NATURE

Resting-state connectivity biomarkers define neurophysiological subtypes of depression

(2016) Andrew T Drysdale et al.   NATURE MEDICINE

Computational psychiatry as a bridge from neuroscience to clinical applications

(2016) Quentin J M Huys et al.   NATURE NEUROSCIENCE

The effects of childhood maltreatment on brain structure, function and connectivity

(2016) Martin H. Teicher et al.   NATURE REVIEWS NEUROSCIENCE

Circuit-wide Transcriptional Profiling Reveals Brain Region-Specific Gene Networks Regulating Depression Susceptibility

(2016) Rosemary C. Bagot et al.   NEURON

NMDA receptors are involved in the antidepressant-like effects of capsaicin following amphetamine withdrawal in male mice

(2016) Shayan Amiri et al.   NEUROSCIENCE

An overview of maternal separation effects on behavioural outcomes in mice: Evidence from a four-stage methodological systematic review

(2016) Saulo G. Tractenberg et al.   NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS

The touchscreen operant platform for assessing cognitive functions in a rat model of depression

(2016) Thao Phuong Tran et al.   PHYSIOLOGY & BEHAVIOR

In-depth behavioral characterization of the corticosterone mouse model and the critical involvement of housing conditions

(2016) Thomas Demuyser et al.   PHYSIOLOGY & BEHAVIOR

Learned helplessness at fifty: Insights from neuroscience.

(2016) Steven F. Maier et al.   PSYCHOLOGICAL REVIEW

Cortisol modulates men’s affiliative responses to acute social stress

(2016) Justus Berger et al.   PSYCHONEUROENDOCRINOLOGY

Structural & functional consequences of chronic psychosocial stress on the microbiome & host

(2016) Aadil Bharwani et al.   PSYCHONEUROENDOCRINOLOGY

Ethological Evaluation of the Effects of Social Defeat Stress in Mice: Beyond the Social Interaction Ratio

(2016) Aron M. Henriques-Alves et al.   Frontiers in Behavioral Neuroscience

Commentary: Ethological Evaluation of the Effects of Social Defeat Stress in Mice: Beyond the Social Interaction Ratio

(2016) Darya A. Meshalkina et al.   Frontiers in Behavioral Neuroscience

Early-Life Stress Paradigm Transiently Alters Maternal Behavior, Dam-Pup Interactions, and Offspring Vocalizations in Mice

(2016) Hanke Heun-Johnson et al.   Frontiers in Behavioral Neuroscience

Elevated paternal glucocorticoid exposure alters the small noncoding RNA profile in sperm and modifies anxiety and depressive phenotypes in the offspring

(2016) A K Short et al.   Translational Psychiatry

Female rats are not more variable than male rats: a meta-analysis of neuroscience studies

(2016) Jill B. Becker et al.   Biology of Sex Differences

Major depressive disorder

(2016) Christian Otte et al.   Nature Reviews Disease Primers

Depression, Neuroimaging and Connectomics: A Selective Overview

(2015) Qiyong Gong et al.   BIOLOGICAL PSYCHIATRY

Clarifying Tissue Clearing

(2015) Douglas S. Richardson et al.   CELL

From adaptive licensing to adaptive pathways: Delivering a flexible life-span approach to bring new drugs to patients

(2015) H-G Eichler et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

Ecological momentary assessment in the investigation of craving and substance use in daily life: A systematic review

(2015) Fuschia Serre et al.   DRUG AND ALCOHOL DEPENDENCE

The preclinical data forum network: A new ECNP initiative to improve data quality and robustness for (preclinical) neuroscience

(2015) Thomas Steckler et al.   EUROPEAN NEUROPSYCHOPHARMACOLOGY

A brief history of the development of antidepressant drugs: From monoamines to glutamate.

(2015) Todd M. Hillhouse et al.   EXPERIMENTAL AND CLINICAL PSYCHOPHARMACOLOGY

Effect of chronic corticosterone application on depression-like behavior in C57BL/6N and C57BL/6J mice

(2015) M. Sturm et al.   GENES BRAIN AND BEHAVIOR

Repeated Psychosocial Stress at Night Affects the Circadian Activity Rhythm of Male Mice

(2015) Manuela S. Bartlang et al.   JOURNAL OF BIOLOGICAL RHYTHMS

Sex Differences in Nucleus Accumbens Transcriptome Profiles Associated with Susceptibility versus Resilience to Subchronic Variable Stress

(2015) G. E. Hodes et al.   JOURNAL OF NEUROSCIENCE

Polygenic dissection of major depression clinical heterogeneity

(2015) Y Milaneschi et al.   MOLECULAR PSYCHIATRY

Genetic compensation induced by deleterious mutations but not gene knockdowns

(2015) Andrea Rossi et al.   NATURE

Modeling psychiatric disorders for developing effective treatments

(2015) Tobias Kaiser et al.   NATURE MEDICINE

Epigenetic and transgenerational reprogramming of brain development

(2015) Tracy L. Bale   NATURE REVIEWS NEUROSCIENCE

Increased dopamine transporter function as a mechanism for dopamine hypoactivity in the adult infralimbic medial prefrontal cortex following adolescent social stress

(2015) Andrew M. Novick et al.   NEUROPHARMACOLOGY

Intergenerational Transmission of Stress in Humans

(2015) Mallory E Bowers et al.   NEUROPSYCHOPHARMACOLOGY

Models of Intergenerational and Transgenerational Transmission of Risk for Psychopathology in Mice

(2015) Torsten Klengel et al.   NEUROPSYCHOPHARMACOLOGY

Neural Correlates of Three Promising Endophenotypes of Depression: Evidence from the EMBARC Study

(2015) Christian A Webb et al.   NEUROPSYCHOPHARMACOLOGY

Immobility in the forced swim test is adaptive and does not reflect depression

(2015) Marc L. Molendijk et al.   PSYCHONEUROENDOCRINOLOGY

The adaptive and maladaptive continuum of stress responses – a hippocampal perspective

(2015) Deepika Suri et al.   REVIEWS IN THE NEUROSCIENCES

Telomere length is associated with oppositional defiant behavior and maternal clinical depression in Latino preschool children

(2015) J M Wojcicki et al.   Translational Psychiatry

R-ketamine: a rapid-onset and sustained antidepressant without psychotomimetic side effects

(2015) C Yang et al.   Translational Psychiatry

Effects of Striatal ΔFosB Overexpression and Ketamine on Social Defeat Stress–Induced Anhedonia in Mice

(2014) Rachel J. Donahue et al.   BIOLOGICAL PSYCHIATRY

Sex differences in animal models of psychiatric disorders

(2014) N Kokras et al.   BRITISH JOURNAL OF PHARMACOLOGY

Naturalistic rodent models of chronic early-life stress

(2014) Jenny Molet et al.   DEVELOPMENTAL PSYCHOBIOLOGY

Evidence Should Trump Intuition by Preferring Inbred Strains to Outbred Stocks in Preclinical Research

(2014) M. F. W. Festing   ILAR JOURNAL

Human transgenerational responses to early-life experience: potential impact on development, health and biomedical research

(2014) Marcus Pembrey et al.   JOURNAL OF MEDICAL GENETICS

Circadian dysregulation of clock genes: clues to rapid treatments in major depressive disorder

(2014) B G Bunney et al.   MOLECULAR PSYCHIATRY

Mind the gap: glucocorticoids modulate hippocampal glutamate tone underlying individual differences in stress susceptibility

(2014) C Nasca et al.   MOLECULAR PSYCHIATRY

The Genetics of Major Depression

(2014) Jonathan Flint et al.   NEURON

Improving and Accelerating Drug Development for Nervous System Disorders

(2014) Diana E. Pankevich et al.   NEURON

Mouse social stress induces increased fear conditioning, helplessness and fatigue to physical challenge together with markers of altered immune and dopamine function

(2014) Damiano Azzinnari et al.   NEUROPHARMACOLOGY

Female mice liberated for inclusion in neuroscience and biomedical research

(2014) Brian J. Prendergast et al.   NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS

Folic acid prevents depressive-like behavior induced by chronic corticosterone treatment in mice

(2014) Priscila B. Rosa et al.   PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR

Individual differences in the peripheral immune system promote resilience versus susceptibility to social stress

(2014) Georgia E. Hodes et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Social defeat stress induces a depression-like phenotype in adolescent male c57BL/6 mice

(2014) Sergio D. Iñiguez et al.   STRESS-THE INTERNATIONAL JOURNAL ON THE BIOLOGY OF STRESS

Zebrafish as an emerging model for studying complex brain disorders

(2014) Allan V. Kalueff et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

Early life stress in fathers improves behavioural flexibility in their offspring

(2014) Katharina Gapp et al.   Nature Communications

Long-term effects of maternal immune activation on depression-like behavior in the mouse

(2014) D Khan et al.   Translational Psychiatry

Mechanisms for Interferon-α-Induced Depression and Neural Stem Cell Dysfunction

(2014) Lian-Shun Zheng et al.   Stem Cell Reports

Endophenotypes in Psychopathology Research: Where Do We Stand?

(2013) Gregory A. Miller et al.   Annual Review of Clinical Psychology

A history of chronic morphine exposure during adolescence increases despair-like behaviour and strain-dependently promotes sociability in abstinent adult mice

(2013) P.E. Lutz et al.   BEHAVIOURAL BRAIN RESEARCH

The H/Rouen mouse model displays depression-like and anxiety-like behaviors

(2013) Malika El Yacoubi et al.   BEHAVIOURAL BRAIN RESEARCH

Psychobiotics: A Novel Class of Psychotropic

(2013) Timothy G. Dinan et al.   BIOLOGICAL PSYCHIATRY

Prenatal Poly(I:C) Exposure and Other Developmental Immune Activation Models in Rodent Systems

(2013) Urs Meyer   BIOLOGICAL PSYCHIATRY

Sex-dependent regulation of hippocampal neurogenesis under basal and chronic stress conditions in rats

(2013) Katharina M. Hillerer et al.   HIPPOCAMPUS

Social, Demographic, and Health Outcomes in the 10 Years Following Adolescent Depression

(2013) Kiyuri Naicker et al.   JOURNAL OF ADOLESCENT HEALTH

Exposure to cocaine regulates inhibitory synaptic transmission from the ventral tegmental area to the nucleus accumbens

(2013) Masago Ishikawa et al.   JOURNAL OF PHYSIOLOGY-LONDON

Genetics of the connectome

(2013) Paul M. Thompson et al.   NEUROIMAGE

The feedback-related negativity (FRN) revisited: New insights into the localization, meaning and network organization

(2013) Tobias U. Hauser et al.   NEUROIMAGE

A Translational Rodent Assay of Affective Biases in Depression and Antidepressant Therapy

(2013) Sarah A Stuart et al.   NEUROPSYCHOPHARMACOLOGY

Behavioral and Neurobiological Effects of Deep Brain Stimulation in a Mouse Model of High Anxiety- and Depression-Like Behavior

(2013) Claudia Schmuckermair et al.   NEUROPSYCHOPHARMACOLOGY

Enkephalin and dynorphin mRNA expression are associated with resilience or vulnerability to chronic social defeat stress

(2013) Patrick Bérubé et al.   PHYSIOLOGY & BEHAVIOR

Where Have I Been? Where Should I Go? Spatial Working Memory on a Radial Arm Maze in a Rat Model of Depression

(2013) Sophie Helene Richter et al.   PLoS One

Psychobiological mechanisms underlying the social buffering of the hypothalamic–pituitary–adrenocortical axis: A review of animal models and human studies across development.

(2013) Camelia E. Hostinar et al.   PSYCHOLOGICAL BULLETIN

Abstinence from repeated amphetamine treatment induces depressive-like behaviors and oxidative damage in rat brain

(2013) Yi Che et al.   PSYCHOPHARMACOLOGY

REM sleep dysregulation in depression: State of the art

(2013) Laura Palagini et al.   SLEEP MEDICINE REVIEWS

Molecular architecture of the mammalian circadian clock

(2013) Carrie L. Partch et al.   TRENDS IN CELL BIOLOGY

Assessment of reward responsiveness in the response bias probabilistic reward task in rats: implications for cross-species translational research

(2013) A Der-Avakian et al.   Translational Psychiatry

Neurobiological Sequelae of Witnessing Stressful Events in Adult Mice

(2012) Brandon L. Warren et al.   BIOLOGICAL PSYCHIATRY

Mechanisms of Rapid Antidepressant Effects of Sleep Deprivation Therapy: Clock Genes and Circadian Rhythms

(2012) Blynn G. Bunney et al.   BIOLOGICAL PSYCHIATRY

Establishing a probabilistic reversal learning test in mice: Evidence for the processes mediating reward-stay and punishment-shift behaviour and for their modulation by serotonin

(2012) Christian Ineichen et al.   NEUROPHARMACOLOGY

Personality traits in rats predict vulnerability and resilience to developing stress-induced depression-like behaviors, HPA axis hyper-reactivity and brain changes in pERK1/2 activity

(2012) Jorge E. Castro et al.   PSYCHONEUROENDOCRINOLOGY

A review of Atypical depression in relation to the course of depression and changes in HPA axis organization

(2012) Veronica O’Keane et al.   PSYCHONEUROENDOCRINOLOGY

Paternal Transmission of Stress-Induced Pathologies

(2011) David M. Dietz et al.   BIOLOGICAL PSYCHIATRY

Following the genes: a framework for animal modeling of psychiatric disorders

(2011) Kevin J Mitchell et al.   BMC BIOLOGY

Current research trends in early life stress and depression: Review of human studies on sensitive periods, gene–environment interactions, and epigenetics

(2011) Christine Heim et al.   EXPERIMENTAL NEUROLOGY

Residual Symptoms in Depressed Outpatients Who Respond by 50% But Do Not Remit to Antidepressant Medication

(2011) Shawn M. McClintock et al.   JOURNAL OF CLINICAL PSYCHOPHARMACOLOGY

Integrated behavioral z-scoring increases the sensitivity and reliability of behavioral phenotyping in mice: Relevance to emotionality and sex

(2011) Jean-Philippe Guilloux et al.   JOURNAL OF NEUROSCIENCE METHODS

City living and urban upbringing affect neural social stress processing in humans

(2011) Florian Lederbogen et al.   NATURE

Drug withdrawal-induced depression: Serotonergic and plasticity changes in animal models

(2011) Thibault Renoir et al.   NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS

Intracranial self-stimulation in FAST and SLOW mice: effects of alcohol and cocaine

(2011) Eric W. Fish et al.   PSYCHOPHARMACOLOGY

The suitability of 129SvEv mice for studying depressive-like behaviour: Both males and females develop learned helplessness

(2010) Sabine Chourbaji et al.   BEHAVIOURAL BRAIN RESEARCH

Brain responses to chronic social defeat stress: Effects on regional oxidative metabolism as a function of a hedonic trait, and gene expression in susceptible and resilient rats

(2010) Margus Kanarik et al.   EUROPEAN NEUROPSYCHOPHARMACOLOGY

The standardization-generalization dilemma: a way out

(2010) F. Josef van der Staay et al.   GENES BRAIN AND BEHAVIOR

A novel chronic social stress paradigm in female mice

(2010) M.V. Schmidt et al.   HORMONES AND BEHAVIOR

Cognitive and neural correlates of depression-like behaviour in socially defeated mice: an animal model of depression with cognitive dysfunction

(2010) Tao Yu et al.   INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY

Males still dominate animal studies

(2010) Irving Zucker et al.   NATURE

Withdrawal from chronic amphetamine produces persistent anxiety-like behavior but temporally-limited reductions in monoamines and neurogenesis in the adult rat dentate gyrus

(2010) Jeffrey L. Barr et al.   NEUROPHARMACOLOGY

Effects of the probiotic Bifidobacterium infantis in the maternal separation model of depression

(2010) L. Desbonnet et al.   NEUROSCIENCE

Sex bias in neuroscience and biomedical research

(2010) Annaliese K. Beery et al.   NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS

Depression is an inflammatory disease, but cell-mediated immune activation is the key component of depression

(2010) Michael Maes   PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY

The glucocorticoid receptor: Pivot of depression and of antidepressant treatment?

(2010) Christoph Anacker et al.   PSYCHONEUROENDOCRINOLOGY

Animal models for depression and the mismatch hypothesis of disease

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