A Dynamic Variation of Pulmonary ACE2 Is Required to Modulate Neutrophilic Inflammation in Response to Pseudomonas aeruginosa Lung Infection in Mice

The renin angiotensin aldosterone system and its therapeutic targets

(2019) Katrina M. Mirabito Colafella et al.   EXPERIMENTAL EYE RESEARCH

Endogenous IL-17A mediated neutrophil infiltration by promoting chemokines expression during chlamydial lung infection

(2019) Sai Qiao et al.   MICROBIAL PATHOGENESIS

Neuroinflammation in hypertension: the renin-angiotensin system versus pro-resolution pathways

(2019) Francesca Elisabeth Mowry et al.   PHARMACOLOGICAL RESEARCH

Limited role of kininogen in the host response during gram-negative pneumonia-derived sepsis

(2018) Chao Ding et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Attenuation of pulmonary ACE2 activity impairs inactivation of des-Arg9 bradykinin/BKB1R axis and facilitates LPS-induced neutrophil infiltration

(2018) Chhinder P. Sodhi et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Targeting the renin–angiotensin system as novel therapeutic strategy for pulmonary diseases

(2018) Wan Shun Daniel Tan et al.   CURRENT OPINION IN PHARMACOLOGY

Interleukin-17A exacerbates disease severity in BALB/c mice susceptible to lung infection with Mycoplasma pulmonis

(2018) Maximillion T. Mize et al.   INFECTION AND IMMUNITY

IL-17 inhibits the accumulation of myeloid-derived suppressor cells in breast cancer via activating STAT3

(2018) Min Ma et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

IL-17–producing ST2 + group 2 innate lymphoid cells play a pathogenic role in lung inflammation

(2018) Ting Cai et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Vγ4+ T Cells: A Novel IL-17-Producing γδ T Subsets during the Early Phase of Chlamydial Airway Infection in Mice

(2018) Li-da Sun et al.   MEDIATORS OF INFLAMMATION

Reduced inflammation and cytokine production in NKLAM deficient mice during Streptococcus pneumoniae infection

(2018) Donald W. Lawrence et al.   PLoS One

rhACE2 Therapy Modifies Bleomycin-Induced Pulmonary Hypertension via Rescue of Vascular Remodeling

(2018) Anandharajan Rathinasabapathy et al.   Frontiers in Physiology

Toll Like Receptor 4 Mediated Lymphocyte Imbalance Induces Nec-Induced Lung Injury

(2018) Hongpeng Jia et al.   SHOCK

Hepatic STAT3 Inhibition Amplifies the Inflammatory Response in Obese Mice During Sepsis

(2018) Lauren Williamson et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Increased IL-4- and IL-17-producing CD8+ cells are related to decreased CD39+CD4+Foxp3+ cells in allergic asthma

(2017) Ping Li et al.   JOURNAL OF ASTHMA

Upregulation of SOCS3 in lung CD4+ T cells in a mouse model of chronic PA lung infection and suppression of Th17-mediated neutrophil recruitment in exogenous SOCS3 transfer in vitro

(2017) Feng-Ming Ding et al.   Molecular Medicine Reports

Multiplicity of Mathematical Modeling Strategies to Search for Molecular and Cellular Insights into Bacteria Lung Infection

(2017) Martina Cantone et al.   Frontiers in Physiology

miRNA-200c-3p is crucial in acute respiratory distress syndrome

(2017) Qiang Liu et al.   Cell Discovery

Interleukin-17A mediates cardiomyocyte apoptosis through Stat3-iNOS pathway

(2016) Sheng-an Su et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Allergen-Induced CD4+T Cell Cytokine Production within Airway Mucosal Dendritic Cell–T Cell Clusters Drives the Local Recruitment of Myeloid Effector Cells

(2016) Tibor Z. Veres et al.   JOURNAL OF IMMUNOLOGY

Pulmonary Angiotensin-Converting Enzyme 2 (ACE2) and Inflammatory Lung Disease

(2016) Hongpeng Jia   SHOCK

Activation of angiotensin-converting enzyme 2 (ACE2) attenuates allergic airway inflammation in rat asthma model

(2016) Vaibhav Shrirang Dhawale et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Rapamycin attenuates acute lung injury induced by LPS through inhibition of Th17 cell proliferation in mice

(2016) Zhao Yan et al.   Scientific Reports

Angiotensin-converting enzyme 2 inhibits lung injury induced by respiratory syncytial virus

(2016) Hongjing Gu et al.   Scientific Reports

The association of renin–angiotensin system blockades and pneumonia requiring admission in patients with COPD

(2016) Junghyun Kim et al.   International Journal of Chronic Obstructive Pulmonary Disease

Pseudomonas aeruginosa infection augments inflammation through miR-301b repression of c-Myb-mediated immune activation and infiltration

(2016) Xuefeng Li et al.   Nature Microbiology

Interleukin-17 Stimulates STAT3-Mediated Endothelial Cell Activation for Neutrophil Recruitment

(2015) Shaopeng Yuan et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

Toll-like receptor 4–mediated lymphocyte influx induces neonatal necrotizing enterocolitis

(2015) Charlotte E. Egan et al.   JOURNAL OF CLINICAL INVESTIGATION

STAT3 is a critical cell-intrinsic regulator of human unconventional T cell numbers and function

(2015) Robert P. Wilson et al.   JOURNAL OF EXPERIMENTAL MEDICINE

IL-17 contributes to neutrophil recruitment but not to control of viral replication during acute mouse adenovirus type 1 respiratory infection

(2014) Mary K. McCarthy et al.   VIROLOGY

Angiotensin-converting enzyme 2 protects from lethal avian influenza A H5N1 infections

(2014) Zhen Zou et al.   Nature Communications

Angiotensin-converting enzyme 2 (ACE2) mediates influenza H7N9 virus-induced acute lung injury

(2014) Penghui Yang et al.   Scientific Reports

Osthole protects lipopolysaccharide-induced acute lung injury in mice by preventing down-regulation of angiotensin-converting enzyme 2

(2013) Yun Shi et al.   EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES

Heme Oxygenase-1 Exerts a Protective Role in Ovalbumin-induced Neutrophilic Airway Inflammation by Inhibiting Th17 Cell-mediated Immune Response

(2013) Yanjie Zhang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Prevalence of multidrug-resistant pseudomonas aeruginosa and carbapenem-resistant enterobacteriaceae among specimens from hospitalized patients with pneumonia and bloodstream infections in the United States from 2000 to 2009

(2013) Marya D. Zilberberg et al.   Journal of Hospital Medicine

T Cell-Derived IL-17 Mediates Epithelial Changes in the Airway and Drives Pulmonary Neutrophilia

(2013) L. K. Fogli et al.   JOURNAL OF IMMUNOLOGY

Hmgb1-TLR4-IL-23-IL-17A Axis Promote Ischemia-Reperfusion Injury in a Cardiac Transplantation Model

(2013) Hongfei Zhu et al.   TRANSPLANTATION

Long-term survival and healthcare utilization outcomes attributable to sepsis and pneumonia

(2012) Andrew Dick et al.   BMC HEALTH SERVICES RESEARCH

IL-17 and TNF-  Sustain Neutrophil Recruitment during Inflammation through Synergistic Effects on Endothelial Activation

(2012) G. K. Griffin et al.   JOURNAL OF IMMUNOLOGY

ACE2, a promising therapeutic target for pulmonary hypertension

(2011) Vinayak Shenoy et al.   CURRENT OPINION IN PHARMACOLOGY

Ectodomain shedding of angiotensin converting enzyme 2 in human airway epithelia

(2009) Hong Peng Jia et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Angiotensin-converting enzyme 2 and new insights into the renin–angiotensin system

(2007) Daniel W. Lambert et al.   BIOCHEMICAL PHARMACOLOGY