Solution NMR: A powerful tool for structural and functional studies of membrane proteins in reconstituted environments

Hydrophobic Functionalization of Polyacrylic Acid as a Versatile Platform for the Development of Polymer Lipid Nanodisks

(2019) Nathaniel Z. Hardin et al.   Small

Higher-Order Clustering of the Transmembrane Anchor of DR5 Drives Signaling

(2019) Liqiang Pan et al.   CELL

Structure determination protocol for transmembrane domain oligomers

(2019) Qingshan Fu et al.   Nature Protocols

Hepatitis C virus sequence divergence preserves p7 viroporin structural and dynamic features

(2019) Benjamin P. Oestringer et al.   Scientific Reports

Formation of pH-Resistant Monodispersed Polymer-Lipid Nanodiscs

(2018) Thirupathi Ravula et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Perturbations of Native Membrane Protein Structure in Alkyl Phosphocholine Detergents: A Critical Assessment of NMR and Biophysical Studies

(2018) Christophe Chipot et al.   CHEMICAL REVIEWS

Production of isotope-labeled proteins in insect cells for NMR

(2018) Bastian Franke et al.   JOURNAL OF BIOMOLECULAR NMR

Low q Bicelles are Mixed Micelles

(2018) Tracy Caldwell et al.   Journal of Physical Chemistry Letters

The Unusual Transmembrane Partition of the Hexameric Channel of the Hepatitis C Virus

(2018) Wen Chen et al.   STRUCTURE

Effect of polymer charge on functional reconstitution of membrane proteins in polymer nanodiscs

(2018) Thirupathi Ravula et al.   CHEMICAL COMMUNICATIONS

Structure of the membrane proximal external region of HIV-1 envelope glycoprotein

(2018) Qingshan Fu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Peptidisc, a simple method for stabilizing membrane proteins in detergent-free solution

(2018) Michael Luke Carlson et al.   eLife

Re-evaluating the p7 viroporin structure

(2018) Benjamin P. Oestringer et al.   NATURE

MT1-MMP Binds Membranes by Opposite Tips of Its β Propeller to Position It for Pericellular Proteolysis

(2018) Tara C. Marcink et al.   STRUCTURE

Structural Insights into the Yersinia pestis Outer Membrane Protein Ail in Lipid Bilayers

(2017) Samit Kumar Dutta et al.   JOURNAL OF PHYSICAL CHEMISTRY B

An Adaptable Phospholipid Membrane Mimetic System for Solution NMR Studies of Membrane Proteins

(2017) Chih-Ta Henry Chien et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Tilted, Uninterrupted, Monomeric HIV-1 gp41 Transmembrane Helix from Residual Dipolar Couplings

(2017) Sai Chaitanya Chiliveri et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Spontaneous Lipid Nanodisc Fomation by Amphiphilic Polymethacrylate Copolymers

(2017) Kazuma Yasuhara et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Protein folding by NMR

(2017) Anastasia Zhuravleva et al.   PROGRESS IN NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY

Ligand modulation of sidechain dynamics in a wild-type human GPCR

(2017) Lindsay D Clark et al.   eLife

Nanodiscs and solution NMR: preparation, application and challenges

(2017) Robbins Puthenveetil et al.   Nanotechnology Reviews

The major outer sheath protein forms distinct conformers and multimeric complexes in the outer membrane and periplasm of Treponema denticola

(2017) Robbins Puthenveetil et al.   Scientific Reports

Reconstitution of the Cytb5-CytP450 Complex in Nanodiscs for Structural Studies using NMR Spectroscopy

(2016) Meng Zhang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Perspective: revisiting the field dependence of TROSY sensitivity

(2016) Koh Takeuchi et al.   JOURNAL OF BIOMOLECULAR NMR

Structural Basis and Functional Role of Intramembrane Trimerization of the Fas/CD95 Death Receptor

(2016) Qingshan Fu et al.   MOLECULAR CELL

Backbone NMR reveals allosteric signal transduction networks in the β1-adrenergic receptor

(2016) Shin Isogai et al.   NATURE

Covalently circularized nanodiscs for studying membrane proteins and viral entry

(2016) Mahmoud L Nasr et al.   NATURE METHODS

A saposin-lipoprotein nanoparticle system for membrane proteins

(2016) Jens Frauenfeld et al.   NATURE METHODS

NMR in drug discovery: A practical guide to identification and validation of ligands interacting with biological macromolecules

(2016) Alvar D. Gossert et al.   PROGRESS IN NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY

Structural basis for membrane anchoring of HIV-1 envelope spike

(2016) J. Dev et al.   SCIENCE

From Nanodiscs to Isotropic Bicelles: A Procedure for Solution Nuclear Magnetic Resonance Studies of Detergent-Sensitive Integral Membrane Proteins

(2016) Aisha Laguerre et al.   STRUCTURE

Controlled Co-reconstitution of Multiple Membrane Proteins in Lipid Bilayer Nanodiscs Using DNA as a Scaffold

(2015) Thomas Raschle et al.   ACS Chemical Biology

G Protein-Coupled Receptor Kinase 2 (GRK2) and 5 (GRK5) Exhibit Selective Phosphorylation of the Neurotensin Receptor in Vitro

(2015) Sayaka Inagaki et al.   BIOCHEMISTRY

Methyl labeling and TROSY NMR spectroscopy of proteins expressed in the eukaryote Pichia pastoris

(2015) Lindsay Clark et al.   JOURNAL OF BIOMOLECULAR NMR

Nanoparticle self-assembly in mixtures of phospholipids with styrene/maleic acid copolymers or fluorinated surfactants

(2015) Carolyn Vargas et al.   Nanoscale

Oncogenic and RASopathy-associated K-RAS mutations relieve membrane-dependent occlusion of the effector-binding site

(2015) Mohammad T. Mazhab-Jafari et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Conformation and Topology of Diacylglycerol Kinase inE.coliMembranes Revealed by Solid-state NMR Spectroscopy

(2014) Yanke Chen et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Live Cell NMR

(2014) Darón I. Freedberg et al.   Annual Review of Biophysics

EmrE dimerization depends on membrane environment

(2014) Supratik Dutta et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Membrane Protein Structural Validation by Oriented Sample Solid-State NMR: Diacylglycerol Kinase

(2014) Dylan T. Murray et al.   BIOPHYSICAL JOURNAL

Rapid Characterization of Molecular Diffusion by NMR Spectroscopy

(2014) Shivanand M. Pudakalakatti et al.   CHEMISTRY-A EUROPEAN JOURNAL

Membrane protein synthesis in cell-free systems: From bio-mimetic systems to bio-membranes

(2014) Rita Sachse et al.   FEBS LETTERS

High-Resolution Structure of a Membrane Protein Transferred from Amphipol to a Lipidic Mesophase

(2014) V. Polovinkin et al.   JOURNAL OF MEMBRANE BIOLOGY

Amphipols for Each Season

(2014) Manuela Zoonens et al.   JOURNAL OF MEMBRANE BIOLOGY

Measuring membrane protein bond orientations in nanodiscs via residual dipolar couplings

(2014) Stefan Bibow et al.   PROTEIN SCIENCE

A detergent-free strategy for the reconstitution of active enzyme complexes from native biological membranes into nanoscale discs

(2013) Ashley R Long et al.   BMC BIOTECHNOLOGY

Optimized Phospholipid Bilayer Nanodiscs Facilitate High-Resolution Structure Determination of Membrane Proteins

(2013) Franz Hagn et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Unusual architecture of the p7 channel from hepatitis C virus

(2013) Bo OuYang et al.   NATURE

Crystal structure of the integral membrane diacylglycerol kinase

(2013) Dianfan Li et al.   NATURE

Detergent/Nanodisc Screening for High-Resolution NMR Studies of an Integral Membrane Protein Containing a Cytoplasmic Domain

(2013) Christos Tzitzilonis et al.   PLoS One

Solution NMR resonance assignment strategies for β-barrel membrane proteins

(2013) Daniel A. Fox et al.   PROTEIN SCIENCE

Optimization of the design and preparation of nanoscale phospholipid bilayers for its application to solution NMR

(2013) Robbins Puthenveetil et al.   PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS

Structural Dynamics and Topology of Phosphorylated Phospholamban Homopentamer Reveal Its Role in the Regulation of Calcium Transport

(2013) Vitaly V. Vostrikov et al.   STRUCTURE

Cell-free Expressed Bacteriorhodopsin in Different Soluble Membrane Mimetics: Biophysical Properties and NMR Accessibility

(2013) Manuel Etzkorn et al.   STRUCTURE

Detergent-Free Formation and Physicochemical Characterization of Nanosized Lipid-Polymer Complexes: Lipodisq

(2012) Marcella C. Orwick et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Characterization of co-translationally formed nanodisc complexes with small multidrug transporters, proteorhodopsin and with the E. coli MraY translocase

(2012) Christian Roos et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Real-Time NMR Characterization of Structure and Dynamics in a Transiently Populated Protein Folding Intermediate

(2012) Enrico Rennella et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Structure of saposin A lipoprotein discs

(2012) K. Popovic et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Nanodiscs versus Macrodiscs for NMR of Membrane Proteins

(2011) Sang Ho Park et al.   BIOCHEMISTRY

Solution NMR spectroscopic characterization of human VDAC-2 in detergent micelles and lipid bilayer nanodiscs

(2011) Tsyr-Yan Yu et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Arrangement of electron transport chain components in bovine mitochondrial supercomplex I1III2IV1

(2011) Thorsten Althoff et al.   EMBO JOURNAL

NMR studies of protein structure and dynamics – A look backwards and forwards

(2011) Lewis E. Kay   JOURNAL OF MAGNETIC RESONANCE

Structural topology of phospholamban pentamer in lipid bilayers by a hybrid solution and solid-state NMR method

(2011) R. Verardi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Structure and Dynamics of the Membrane-Bound Form of Pf1 Coat Protein: Implications of Structural Rearrangement for Virus Assembly

(2010) Sang Ho Park et al.   BIOPHYSICAL JOURNAL

NMR Structural and Dynamical Investigation of the Isolated Voltage-Sensing Domain of the Potassium Channel KvAP: Implications for Voltage Gating

(2010) Zakhar O. Shenkarev et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

The HADDOCK web server for data-driven biomolecular docking

(2010) Sjoerd J de Vries et al.   Nature Protocols

Engineering extended membrane scaffold proteins for self-assembly of soluble nanoscale lipid bilayers

(2010) Y. V. Grinkova et al.   PROTEIN ENGINEERING DESIGN & SELECTION

Membrane protein assembly into Nanodiscs

(2009) Timothy H. Bayburt et al.   FEBS LETTERS

A refinement protocol to determine structure, topology, and depth of insertion of membrane proteins using hybrid solution and solid-state NMR restraints

(2009) Lei Shi et al.   JOURNAL OF BIOMOLECULAR NMR

Integral Membrane Proteins in Nanodiscs Can Be Studied by Solution NMR Spectroscopy

(2009) Julian M. Glück et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Mixing and Matching Detergents for Membrane Protein NMR Structure Determination

(2009) Linda Columbus et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Structural and Functional Characterization of the Integral Membrane Protein VDAC-1 in Lipid Bilayer Nanodiscs

(2009) Thomas Raschle et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Membrane Proteins Solubilized Intact in Lipid Containing Nanoparticles Bounded by Styrene Maleic Acid Copolymer

(2009) Timothy J. Knowles et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Structure of an integrin  IIb 3 transmembrane-cytoplasmic heterocomplex provides insight into integrin activation

(2009) J. Yang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Structure and topology of monomeric phospholamban in lipid membranes determined by a hybrid solution and solid-state NMR approach

(2009) N. J. Traaseth et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Recent advances in the application of solution NMR spectroscopy to multi-span integral membrane proteins

(2009) Hak Jun Kim et al.   PROGRESS IN NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY

Solution Nuclear Magnetic Resonance Structure of Membrane-Integral Diacylglycerol Kinase

(2009) W. D. Van Horn et al.   SCIENCE

Microscale NMR Screening of New Detergents for Membrane Protein Structural Biology

(2008) Qinghai Zhang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Self-assembly of single integral membrane proteins into soluble nanoscale phospholipid bilayers

(2003) Timothy H. Bayburt et al.   PROTEIN SCIENCE