A saposin-lipoprotein nanoparticle system for membrane proteins

Structural and Thermodynamic Basis of Epitope Binding by Neutralizing and Nonneutralizing Forms of the Anti-HIV-1 Antibody 4E10

(2015) Edurne Rujas et al.   JOURNAL OF VIROLOGY

Structure of the TRPA1 ion channel suggests regulatory mechanisms

(2015) Candice E. Paulsen et al.   NATURE

Smaller Nanodiscs are Suitable for Studying Protein Lipid Interactions by Solution NMR

(2015) Xiaoming Wang et al.   PROTEIN JOURNAL

Novel microscale approaches for easy, rapid determination of protein stability in academic and commercial settings

(2014) Crispin G. Alexander et al.   BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS

Architecture and conformational switch mechanism of the ryanodine receptor

(2014) Rouslan G. Efremov et al.   NATURE

Selectivity mechanism of a bacterial homolog of the human drug-peptide transporters PepT1 and PepT2

(2014) Fatma Guettou et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Host Controls of HIV Neutralizing Antibodies

(2014) B. F. Haynes et al.   SCIENCE

Structural insights into substrate recognition in proton-dependent oligopeptide transporters

(2013) Fatma Guettou et al.   EMBO REPORTS

Optimized Phospholipid Bilayer Nanodiscs Facilitate High-Resolution Structure Determination of Membrane Proteins

(2013) Franz Hagn et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Inhibition of the HIV-1 Spike by Single-PG9/16-Antibody Binding Suggests a Coordinated-Activation Model for Its Three Protomeric Units

(2013) R. Loving et al.   JOURNAL OF VIROLOGY

Structure of the TRPV1 ion channel determined by electron cryo-microscopy

(2013) Maofu Liao et al.   NATURE

Engineered nanostructured β-sheet peptides protect membrane proteins

(2013) Houchao Tao et al.   NATURE METHODS

Quantifying the local resolution of cryo-EM density maps

(2013) Alp Kucukelbir et al.   NATURE METHODS

Electron counting and beam-induced motion correction enable near-atomic-resolution single-particle cryo-EM

(2013) Xueming Li et al.   NATURE METHODS

Nanobody Mediated Crystallization of an Archeal Mechanosensitive Channel

(2013) Christian Löw et al.   PLoS One

Asymmetric recognition of the HIV-1 trimer by broadly neutralizing antibody PG9

(2013) Jean-Philippe Julien et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Increased Functional Stability and Homogeneity of Viral Envelope Spikes through Directed Evolution

(2013) Daniel P. Leaman et al.   PLoS Pathogens

Structure–function correlations of pulmonary surfactant protein SP-B and the saposin-like family of proteins

(2012) Bárbara Olmeda et al.   EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERS

SIMPLE: Software for ab initio reconstruction of heterogeneous single-particles

(2012) Dominika Elmlund et al.   JOURNAL OF STRUCTURAL BIOLOGY

RELION: Implementation of a Bayesian approach to cryo-EM structure determination

(2012) Sjors H.W. Scheres   JOURNAL OF STRUCTURAL BIOLOGY

Structure of the TatC core of the twin-arginine protein transport system

(2012) Sarah E. Rollauer et al.   NATURE

Broad and potent neutralization of HIV-1 by a gp41-specific human antibody

(2012) Jinghe Huang et al.   NATURE

Prevention of overfitting in cryo-EM structure determination

(2012) Sjors H W Scheres et al.   NATURE METHODS

Structure of saposin A lipoprotein discs

(2012) K. Popovic et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Maturation cleavage of the murine leukemia virus Env precursor separates the transmembrane subunits to prime it for receptor triggering

(2012) R. Loving et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Nanodiscs versus Macrodiscs for NMR of Membrane Proteins

(2011) Sang Ho Park et al.   BIOCHEMISTRY

The development of vaccines: how the past led to the future

(2011) Stanley A. Plotkin et al.   NATURE REVIEWS MICROBIOLOGY

Cryo-EM structure of the ribosome–SecYE complex in the membrane environment

(2011) Jens Frauenfeld et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Functional Stability of Unliganded Envelope Glycoprotein Spikes among Isolates of Human Immunodeficiency Virus Type 1 (HIV-1)

(2011) Nitish Agrawal et al.   PLoS One

Nonmicellar systems for solution NMR spectroscopy of membrane proteins

(2010) Thomas Raschle et al.   CURRENT OPINION IN STRUCTURAL BIOLOGY

Single-particle cryoelectron microscopy analysis reveals the HIV-1 spike as a tripod structure

(2010) S.-R. Wu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Genome-wide analysis of integral membrane proteins from eubacterial, archaean, and eukaryotic organisms

(2010) Erik Wallin et al.   PROTEIN SCIENCE

Membrane protein assembly into Nanodiscs

(2009) Timothy H. Bayburt et al.   FEBS LETTERS

Membrane Proteins Solubilized Intact in Lipid Containing Nanoparticles Bounded by Styrene Maleic Acid Copolymer

(2009) Timothy J. Knowles et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Structure of the BK potassium channel in a lipid membrane from electron cryomicroscopy

(2009) Liguo Wang et al.   NATURE

Broad and Potent Neutralizing Antibodies from an African Donor Reveal a New HIV-1 Vaccine Target

(2009) L. M. Walker et al.   SCIENCE

Crystal Structures of Human Saposins C and D: Implications for Lipid Recognition and Membrane Interactions

(2008) Maxim Rossmann et al.   STRUCTURE