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Title
Ligand modulation of sidechain dynamics in a wild-type human GPCR
Authors
Keywords
-
Journal
eLife
Volume 6, Issue -, Pages -
Publisher
eLife Sciences Organisation, Ltd.
Online
2017-10-06
DOI
10.7554/elife.28505
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- (2016) A. J. Venkatakrishnan et al. NATURE
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- (2016) Matthew T. Eddy et al. STRUCTURE
- Identification of a Conformational Equilibrium That Determines the Efficacy and Functional Selectivity of the μ-Opioid Receptor
- (2015) Junya Okude et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Structural Insights into the Dynamic Process of β 2 -Adrenergic Receptor Signaling
- (2015) Aashish Manglik et al. CELL
- Methyl labeling and TROSY NMR spectroscopy of proteins expressed in the eukaryote Pichia pastoris
- (2015) Lindsay Clark et al. JOURNAL OF BIOMOLECULAR NMR
- History and Perspectives of A2AAdenosine Receptor Antagonists as Potential Therapeutic Agents
- (2015) Delia Preti et al. MEDICINAL RESEARCH REVIEWS
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- (2015) Weijiao Huang et al. NATURE
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- (2015) Rémy Sounier et al. NATURE
- Functional Dynamics of Deuterated β2-Adrenergic Receptor in Lipid Bilayers Revealed by NMR Spectroscopy
- (2014) Yutaka Kofuku et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Role of Electrostatic Interactions in Binding of Peptides and Intrinsically Disordered Proteins to Their Folded Targets. 1. NMR and MD Characterization of the Complex between the c-Crk N-SH3 Domain and the Peptide Sos
- (2014) Yi Xue et al. BIOCHEMISTRY
- Loss of constitutive activity is correlated with increased thermostability of the human adenosine A2Areceptor
- (2013) Nicolas Bertheleme et al. BRITISH JOURNAL OF PHARMACOLOGY
- The Dynamic Process of β2-Adrenergic Receptor Activation
- (2013) Rie Nygaard et al. CELL
- The effect of α-mating factor secretion signal mutations on recombinant protein expression in Pichia pastoris
- (2013) Geoff P. Lin-Cereghino et al. GENE
- Adenosine A2A Receptor as a Drug Discovery Target
- (2013) Manuel de Lera Ruiz et al. JOURNAL OF MEDICINAL CHEMISTRY
- The Membrane Protein LeuT in Micellar Systems: Aggregation Dynamics and Detergent Binding to the S2 Site
- (2013) George Khelashvili et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Structure-Function of the G Protein–Coupled Receptor Superfamily
- (2012) Vsevolod Katritch et al. Annual Review of Pharmacology and Toxicology
- G-protein-coupled receptor inactivation by an allosteric inverse-agonist antibody
- (2012) Tomoya Hino et al. NATURE
- Protein activity regulation by conformational entropy
- (2012) Shiou-Ru Tzeng et al. NATURE
- Structural Basis for Allosteric Regulation of GPCRs by Sodium Ions
- (2012) W. Liu et al. SCIENCE
- Biased Signaling Pathways in 2-Adrenergic Receptor Characterized by 19F-NMR
- (2012) J. J. Liu et al. SCIENCE
- Efficacy of the β2-adrenergic receptor is determined by conformational equilibrium in the transmembrane region
- (2012) Yutaka Kofuku et al. Nature Communications
- Structural Analysis of Large Protein Complexes Using Solvent Paramagnetic Relaxation Enhancements
- (2011) Tobias Madl et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- MATCH: An atom-typing toolset for molecular mechanics force fields
- (2011) Joseph D. Yesselman et al. JOURNAL OF COMPUTATIONAL CHEMISTRY
- An Optimized Relaxation-Based Coherence Transfer NMR Experiment for the Measurement of Side-Chain Order in Methyl-Protonated, Highly Deuterated Proteins
- (2011) Hechao Sun et al. JOURNAL OF PHYSICAL CHEMISTRY B
- Agonist-bound adenosine A2A receptor structures reveal common features of GPCR activation
- (2011) Guillaume Lebon et al. NATURE
- Structure of the human histamine H1 receptor complex with doxepin
- (2011) Tatsuro Shimamura et al. NATURE
- Crystal structure of metarhodopsin II
- (2011) Hui-Woog Choe et al. NATURE
- The structural basis for agonist and partial agonist action on a β1-adrenergic receptor
- (2011) Tony Warne et al. NATURE
- Structure of a nanobody-stabilized active state of the β2 adrenoceptor
- (2011) Søren G. F. Rasmussen et al. NATURE
- Structure and function of an irreversible agonist-β2 adrenoceptor complex
- (2011) Daniel M. Rosenbaum et al. NATURE
- Crystal structure of the β2 adrenergic receptor–Gs protein complex
- (2011) Søren G. F. Rasmussen et al. NATURE
- Activation mechanism of the 2-adrenergic receptor
- (2011) R. O. Dror et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Pathway and mechanism of drug binding to G-protein-coupled receptors
- (2011) Ron O. Dror et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Structure of an Agonist-Bound Human A2A Adenosine Receptor
- (2011) F. Xu et al. SCIENCE
- Molecular Simulations of Dodecyl-β-maltoside Micelles in Water: Influence of the Headgroup Conformation and Force Field Parameters
- (2010) Stéphane Abel et al. JOURNAL OF PHYSICAL CHEMISTRY B
- Ligand-specific regulation of the extracellular surface of a G-protein-coupled receptor
- (2010) Michael P. Bokoch et al. NATURE
- The role of conformational entropy in molecular recognition by calmodulin
- (2010) Michael S Marlow et al. Nature Chemical Biology
- Transmembrane signaling by GPCRs: Insight from rhodopsin and opsin structures
- (2010) Hui-Woog Choe et al. NEUROPHARMACOLOGY
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- (2010) T. L. Religa et al. SCIENCE
- Comparison of functional non-glycosylated GPCRs expression in Pichia pastoris
- (2009) Takami Yurugi-Kobayashi et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Observation of “Ionic Lock” Formation in Molecular Dynamics Simulations of Wild-Type β1and β2Adrenergic Receptors
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- CHARMM: The biomolecular simulation program
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- The 2.6 Angstrom Crystal Structure of a Human A2A Adenosine Receptor Bound to an Antagonist
- (2008) V.-P. Jaakola et al. SCIENCE
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