Regulation of mononuclear phagocyte function by the microbiota at mucosal sites

Microbial network disturbances in relapsing refractory Crohn’s disease

(2019) Bahtiyar Yilmaz et al.   NATURE MEDICINE

The Short Chain Fatty Acid Butyrate Imprints an Antimicrobial Program in Macrophages

(2019) Julie Schulthess et al.   IMMUNITY

The vaginal eukaryotic DNA virome and preterm birth

(2018) Kristine M. Wylie et al.   AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY

Dietary Fiber Confers Protection against Flu by Shaping Ly6c − Patrolling Monocyte Hematopoiesis and CD8 + T Cell Metabolism

(2018) Aurélien Trompette et al.   IMMUNITY

Critical Role for the Microbiota in CX 3 CR1 + Intestinal Mononuclear Phagocyte Regulation of Intestinal T Cell Responses

(2018) Myunghoo Kim et al.   IMMUNITY

Tissue-resident macrophages in the intestine are long lived and defined by Tim-4 and CD4 expression

(2018) Tovah N. Shaw et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Tissue-Specific Immunity at the Oral Mucosal Barrier

(2018) Niki M. Moutsopoulos et al.   TRENDS IN IMMUNOLOGY

Self-Maintaining Gut Macrophages Are Essential for Intestinal Homeostasis

(2018) Sebastiaan De Schepper et al.   CELL

Aryl Hydrocarbon Receptor Promotes IL-10 Expression in Inflammatory Macrophages Through Src-STAT3 Signaling Pathway

(2018) Junyu Zhu et al.   Frontiers in Immunology

Antibiotics induce sustained dysregulation of intestinal T cell immunity by perturbing macrophage homeostasis

(2018) Nicholas A. Scott et al.   Science Translational Medicine

On-going Mechanical Damage from Mastication Drives Homeostatic Th17 Cell Responses at the Oral Barrier

(2017) Nicolas Dutzan et al.   IMMUNITY

Exposure to Bacterial CpG DNA Protects from Airway Allergic Inflammation by Expanding Regulatory Lung Interstitial Macrophages

(2017) Catherine Sabatel et al.   IMMUNITY

Aryl Hydrocarbon Receptor Controls Monocyte Differentiation into Dendritic Cells versus Macrophages

(2017) Christel Goudot et al.   IMMUNITY

Transcriptional and functional profiling defines human small intestinal macrophage subsets

(2017) Anna Bujko et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Diet-Derived Short Chain Fatty Acids Stimulate Intestinal Epithelial Cells To Induce Mucosal Tolerogenic Dendritic Cells

(2017) Gera Goverse et al.   JOURNAL OF IMMUNOLOGY

Microbial Ecology along the Gastrointestinal Tract

(2017) Ethan T. Hillman et al.   MICROBES AND ENVIRONMENTS

Feedback control of AHR signalling regulates intestinal immunity

(2017) Chris Schiering et al.   NATURE

TGFβR signalling controls CD103+CD11b+ dendritic cell development in the intestine

(2017) C. C. Bain et al.   Nature Communications

Commensal microbiota maintains alveolar macrophages with a low level of CCL24 production to generate anti-metastatic tumor activity

(2017) Min Cheng et al.   Scientific Reports

Evidence that the endometrial microbiota has an effect on implantation success or failure

(2016) Inmaculada Moreno et al.   AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY

Airway Microbiota Determines Innate Cell Inflammatory or Tissue Remodeling Profiles in Lung Transplantation

(2016) Eric Bernasconi et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Retinoic Acid and Retinoic Acid Receptors as Pleiotropic Modulators of the Immune System

(2016) Alexandre Larange et al.   Annual Review of Immunology

The Microbiome and the Respiratory Tract

(2016) Robert P. Dickson et al.   Annual Review of Physiology

Lymphoid-Tissue-Resident Commensal Bacteria Promote Members of the IL-10 Cytokine Family to Establish Mutualism

(2016) Thomas C. Fung et al.   IMMUNITY

IRF8 Transcription-Factor-Dependent Classical Dendritic Cells Are Essential for Intestinal T Cell Homeostasis

(2016) Katarzyna M. Luda et al.   IMMUNITY

The microbial environment and its influence on asthma prevention in early life

(2016) Erika von Mutius   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Uropathogenic Escherichia coli strain CFT073 disrupts NLRP3 inflammasome activation

(2016) Anna Waldhuber et al.   JOURNAL OF CLINICAL INVESTIGATION

New Systems for Studying Intercellular Interactions in Bacterial Vaginosis

(2016) Melissa M. Herbst-Kralovetz et al.   JOURNAL OF INFECTIOUS DISEASES

Inflammatory cues enhance TGFβ activation by distinct subsets of human intestinal dendritic cells via integrin αvβ8

(2016) T M Fenton et al.   Mucosal Immunology

Characterization of the human immune cell network at the gingival barrier

(2016) N Dutzan et al.   Mucosal Immunology

The Human Intestinal Microbiome in Health and Disease

(2016) Susan V. Lynch et al.   NEW ENGLAND JOURNAL OF MEDICINE

Trained immunity: A program of innate immune memory in health and disease

(2016) M. G. Netea et al.   SCIENCE

IL-10 control of CD11c+ myeloid cells is essential to maintain immune homeostasis in the small and large intestine

(2016) Mathilde J.H. Girard-Madoux et al.   Oncotarget

Evidence for a dynamic role for mononuclear phagocytes during endometrial repair and remodelling

(2016) Fiona L. Cousins et al.   Scientific Reports

The vaginal mycobiome: A contemporary perspective on fungi in women's health and diseases

(2016) L. Latéy Bradford et al.   Virulence

Causality of small and large intestinal microbiota in weight regulation and insulin resistance

(2016) Torsten P.M. Scheithauer et al.   Molecular Metabolism

Diet-dependent, microbiota-independent regulation of IL-10-producing lamina propria macrophages in the small intestine

(2016) Takanori Ochi et al.   Scientific Reports

Ablating the aryl hydrocarbon receptor (AhR) in CD11c+ cells perturbs intestinal epithelium development and intestinal immunity

(2016) Song Hui Chng et al.   Scientific Reports

Colonization of the upper genital tract by vaginal bacterial species in nonpregnant women

(2015) Caroline M. Mitchell et al.   AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY

Serotonin 5-HT2 receptor activation prevents allergic asthma in a mouse model

(2015) Felix Nau et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Indigenous Bacteria from the Gut Microbiota Regulate Host Serotonin Biosynthesis

(2015) Jessica M. Yano et al.   CELL

Compartment-specific immunity in the human gut: properties and functions of dendritic cells in the colon versus the ileum

(2015) Elizabeth R Mann et al.   GUT

Distinct Murine Mucosal Langerhans Cell Subsets Develop from Pre-dendritic Cells and Monocytes

(2015) Tal Capucha et al.   IMMUNITY

Microbiota regulate the ability of lung dendritic cells to induce IgA class-switch recombination and generate protective gastrointestinal immune responses

(2015) Darren Ruane et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Immunometabolism governs dendritic cell and macrophage function

(2015) Luke A.J. O’Neill et al.   JOURNAL OF EXPERIMENTAL MEDICINE

MyD88 Signaling Regulates Steady-State Migration of Intestinal CD103+Dendritic Cells Independently of TNF-α and the Gut Microbiota

(2015) Karin Hägerbrand et al.   JOURNAL OF IMMUNOLOGY

The Microbiota and Microbiome in Aging: Potential Implications in Health and Age-Related Diseases

(2015) Heidi J. Zapata et al.   JOURNAL OF THE AMERICAN GERIATRICS SOCIETY

Macrophages Subvert Adaptive Immunity to Urinary Tract Infection

(2015) Gabriela Mora-Bau et al.   PLoS Pathogens

The effect of short-chain fatty acids on human monocyte-derived dendritic cells

(2015) Claudia Nastasi et al.   Scientific Reports

Crosstalk between Sentinel and Helper Macrophages Permits Neutrophil Migration into Infected Uroepithelium

(2014) Marzena Schiwon et al.   CELL

Increased Production of Retinoic Acid by Intestinal Macrophages Contributes to Their Inflammatory Phenotype in Patients With Crohn's Disease

(2014) Theodore J. Sanders et al.   GASTROENTEROLOGY

Intra-uterine microbial colonization and occurrence of endometritis in women with endometriosis†

(2014) Khaleque Newaz Khan et al.   HUMAN REPRODUCTION

Macrophage-Restricted Interleukin-10 Receptor Deficiency, but Not IL-10 Deficiency, Causes Severe Spontaneous Colitis

(2014) Ehud Zigmond et al.   IMMUNITY

Diet, Metabolites, and “Western-Lifestyle” Inflammatory Diseases

(2014) Alison N. Thorburn et al.   IMMUNITY

Activation of Gpr109a, Receptor for Niacin and the Commensal Metabolite Butyrate, Suppresses Colonic Inflammation and Carcinogenesis

(2014) Nagendra Singh et al.   IMMUNITY

Differences in vaginal microbiome in African American women versus women of European ancestry

(2014) Jennifer M. Fettweis et al.   MICROBIOLOGY-SGM

Lymph-borne CD8α+ dendritic cells are uniquely able to cross-prime CD8+ T cells with antigen acquired from intestinal epithelial cells

(2014) V Cerovic et al.   Mucosal Immunology

Constant replenishment from circulating monocytes maintains the macrophage pool in the intestine of adult mice

(2014) Calum C Bain et al.   NATURE IMMUNOLOGY

Gut microbiota metabolism of dietary fiber influences allergic airway disease and hematopoiesis

(2014) Aurélien Trompette et al.   NATURE MEDICINE

The microbial metabolite butyrate regulates intestinal macrophage function via histone deacetylase inhibition

(2014) Pamela V. Chang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Microbiota-Dependent Crosstalk Between Macrophages and ILC3 Promotes Intestinal Homeostasis

(2014) A. Mortha et al.   SCIENCE

Intestinal macrophages and dendritic cells: what's the difference?

(2014) Vuk Cerovic et al.   TRENDS IN IMMUNOLOGY

Commensal bacteria-dependent select expression of CXCL2 contributes to periodontal tissue homeostasis

(2013) Camille Zenobia et al.   CELLULAR MICROBIOLOGY

Tryptophan Catabolites from Microbiota Engage Aryl Hydrocarbon Receptor and Balance Mucosal Reactivity via Interleukin-22

(2013) Teresa Zelante et al.   IMMUNITY

The role of lung dendritic cell subsets in immunity to respiratory viruses

(2013) Katrijn Neyt et al.   IMMUNOLOGICAL REVIEWS

Retinoic acid controls the homeostasis of pre-cDC–derived splenic and intestinal dendritic cells

(2013) Christopher A. Klebanoff et al.   JOURNAL OF EXPERIMENTAL MEDICINE

CD14hi HLA-DRdim macrophages, with a resemblance to classical blood monocytes, dominate inflamed mucosa in Crohnˈs disease

(2013) Susanne Thiesen et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Dendritic cells of the oral mucosa

(2013) A-H Hovav   Mucosal Immunology

Division of labor between lung dendritic cells and macrophages in the defense against pulmonary infections

(2013) M Guilliams et al.   Mucosal Immunology

Comparative transcriptional and functional profiling defines conserved programs of intestinal DC differentiation in humans and mice

(2013) Payal B Watchmaker et al.   NATURE IMMUNOLOGY

Serotonin Is a Key Factor for Mouse Red Blood Cell Survival

(2013) Pascal Amireault et al.   PLoS One

Bacterial colonization dampens influenza-mediated acute lung injury via induction of M2 alveolar macrophages

(2013) Jian Wang et al.   Nature Communications

Vaginal Microbiome: Rethinking Health and Disease

(2012) Bing Ma et al.   Annual Review of Microbiology

Loss of Interleukin-10 Signaling and Infantile Inflammatory Bowel Disease: Implications for Diagnosis and Therapy

(2012) Daniel Kotlarz et al.   GASTROENTEROLOGY

IL-10R Polymorphisms Are Associated with Very-early-onset Ulcerative Colitis

(2012) Christopher J. Moran et al.   INFLAMMATORY BOWEL DISEASES

Inflammation switches the differentiation program of Ly6Chimonocytes from antiinflammatory macrophages to inflammatory dendritic cells in the colon

(2012) Aymeric Rivollier et al.   JOURNAL OF EXPERIMENTAL MEDICINE

The importance of the macrophage within the human endometrium

(2012) U. Thiruchelvam et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Resident and pro-inflammatory macrophages in the colon represent alternative context-dependent fates of the same Ly6Chi monocyte precursors

(2012) C C Bain et al.   Mucosal Immunology

Retinoic acid regulates the development of a gut-homing precursor for intestinal dendritic cells

(2012) R Zeng et al.   Mucosal Immunology

Intestinal CD103− dendritic cells migrate in lymph and prime effector T cells

(2012) V Cerovic et al.   Mucosal Immunology

Short-Chain Fatty Acids Induce Pro-Inflammatory Cytokine Production Alone and in Combination with Toll-Like Receptor Ligands

(2011) Paria Mirmonsef et al.   AMERICAN JOURNAL OF REPRODUCTIVE IMMUNOLOGY

The genital econiche: focus on microbiota and bacterial vaginosis

(2011) Dan Danielsson et al.   Annals of the New York Academy of Sciences

Intestinal Tolerance Requires Gut Homing and Expansion of FoxP3+ Regulatory T Cells in the Lamina Propria

(2011) Usriansyah Hadis et al.   IMMUNITY

Human Gut-Specific Homeostatic Dendritic Cells Are Generated from Blood Precursors by the Gut Microenvironment

(2011) Elizabeth R. Mann et al.   INFLAMMATORY BOWEL DISEASES

Lung CD103+ Dendritic Cells Efficiently Transport Influenza Virus to the Lymph Node and Load Viral Antigen onto MHC Class I for Presentation to CD8 T Cells

(2011) A. W. S. Ho et al.   JOURNAL OF IMMUNOLOGY

The Bile Acid Receptor GPBAR-1 (TGR5) Modulates Integrity of Intestinal Barrier and Immune Response to Experimental Colitis

(2011) Sabrina Cipriani et al.   PLoS One

Histone deacetylase inhibitors impair innate immune responses to Toll-like receptor agonists and to infection

(2010) T. Roger et al.   BLOOD

Escherichia coli contamination of menstrual blood and effect of bacterial endotoxin on endometriosis

(2010) Khaleque Newaz Khan et al.   FERTILITY AND STERILITY

Commensal microbiota induce LPS hyporesponsiveness in colonic macrophages via the production of IL-10

(2010) Yoshiyasu Ueda et al.   INTERNATIONAL IMMUNOLOGY

The Human Oral Microbiome

(2010) F. E. Dewhirst et al.   JOURNAL OF BACTERIOLOGY

Blockade of Dendritic Cell Development by Bacterial Fermentation Products Butyrate and Propionate through a Transporter (Slc5a8)-dependent Inhibition of Histone Deacetylases

(2010) Nagendra Singh et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Temporal changes in dendritic cell subsets, cross-priming and costimulation via CD70 control CD8+ T cell responses to influenza

(2010) André Ballesteros-Tato et al.   NATURE IMMUNOLOGY

Poor Reliability of Vaginal and Endocervical Cultures for Evaluating Microbiology of Endometrial Cavity in Women with Chronic Endometritis

(2009) Ettore Cicinelli et al.   GYNECOLOGIC AND OBSTETRIC INVESTIGATION

Lung interstitial macrophages alter dendritic cell functions to prevent airway allergy in mice

(2009) Denis Bedoret et al.   JOURNAL OF CLINICAL INVESTIGATION

The Bile Acid Receptor FXR Is a Modulator of Intestinal Innate Immunity

(2009) P. Vavassori et al.   JOURNAL OF IMMUNOLOGY

Interleukin 10 acts on regulatory T cells to maintain expression of the transcription factor Foxp3 and suppressive function in mice with colitis

(2009) Masako Murai et al.   NATURE IMMUNOLOGY

Abnormal Immunological Profile and Vaginal Microbiota in Women Prone to Urinary Tract Infections

(2008) P. V. Kirjavainen et al.   Clinical and Vaccine Immunology

Endometrial dendritic cell populations during the normal menstrual cycle

(2008) L. Schulke et al.   HUMAN REPRODUCTION

Sustained desensitization to bacterial Toll-like receptor ligands after resolutionof respiratory influenza infection

(2008) Arnaud Didierlaurent et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Dendritic cells and macrophages in the genitourinary tract

(2008) N Iijima et al.   Mucosal Immunology

Role of retinoic acid in the imprinting of gut-homing IgA-secreting cells

(2008) J. Rodrigo Mora et al.   SEMINARS IN IMMUNOLOGY