TGFβR signalling controls CD103+CD11b+ dendritic cell development in the intestine

Yolk Sac Macrophages, Fetal Liver, and Adult Monocytes Can Colonize an Empty Niche and Develop into Functional Tissue-Resident Macrophages

(2016) Lianne van de Laar et al.   IMMUNITY

IRF8 Transcription-Factor-Dependent Classical Dendritic Cells Are Essential for Intestinal T Cell Homeostasis

(2016) Katarzyna M. Luda et al.   IMMUNITY

The transcription factor Zeb2 regulates development of conventional and plasmacytoid DCs by repressing Id2

(2016) Charlotte L. Scott et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Comparative genomics analysis of mononuclear phagocyte subsets confirms homology between lymphoid tissue-resident and dermal XCR1+ DCs in mouse and human and distinguishes them from Langerhans cells

(2016) Sabrina Carpentier et al.   JOURNAL OF IMMUNOLOGICAL METHODS

CD101 inhibits the expansion of colitogenic T cells

(2016) R Schey et al.   Mucosal Immunology

Classical dendritic cells are required for dietary antigen–mediated induction of peripheral Treg cells and tolerance

(2016) Daria Esterházy et al.   NATURE IMMUNOLOGY

Stromal cells control the epithelial residence of DCs and memory T cells by regulated activation of TGF-β

(2016) Javed Mohammed et al.   NATURE IMMUNOLOGY

Smad2 and Smad3 Inversely Regulate TGF-β Autoinduction in Clostridium butyricum-Activated Dendritic Cells

(2015) Ikkou Kashiwagi et al.   IMMUNITY

The lymph nodes draining the small intestine and colon are anatomically separate and immunologically distinct

(2015) S A Houston et al.   Mucosal Immunology

Colonic tolerance develops in the iliac lymph nodes and can be established independent of CD103+ dendritic cells

(2015) S Veenbergen et al.   Mucosal Immunology

Generation and transcriptional programming of intestinal dendritic cells: essential role of retinoic acid

(2015) R Zeng et al.   Mucosal Immunology

Signal regulatory protein alpha (SIRPα) regulates the homeostasis of CD103+CD11b+DCs in the intestinal lamina propria

(2014) Charlotte L. Scott et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Lymph-borne CD8α+ dendritic cells are uniquely able to cross-prime CD8+ T cells with antigen acquired from intestinal epithelial cells

(2014) V Cerovic et al.   Mucosal Immunology

CCR2+CD103− intestinal dendritic cells develop from DC-committed precursors and induce interleukin-17 production by T cells

(2014) C L Scott et al.   Mucosal Immunology

Constant replenishment from circulating monocytes maintains the macrophage pool in the intestine of adult mice

(2014) Calum C Bain et al.   NATURE IMMUNOLOGY

Intestinal macrophages and dendritic cells: what's the difference?

(2014) Vuk Cerovic et al.   TRENDS IN IMMUNOLOGY

Genetic Tracing via DNGR-1 Expression History Defines Dendritic Cells as a Hematopoietic Lineage

(2013) Barbara U. Schraml et al.   CELL

Chronic hypoxia reprograms human immature dendritic cells by inducing a proinflammatory phenotype and TREM-1 expression

(2013) Daniele Pierobon et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Dendritic cell subsets in the intestinal lamina propria: Ontogeny and function

(2013) Emma K. Persson et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

IRF4 Transcription-Factor-Dependent CD103+CD11b+ Dendritic Cells Drive Mucosal T Helper 17 Cell Differentiation

(2013) Emma K. Persson et al.   IMMUNITY

IRF4 Transcription Factor-Dependent CD11b+ Dendritic Cells in Human and Mouse Control Mucosal IL-17 Cytokine Responses

(2013) Andreas Schlitzer et al.   IMMUNITY

Intestinal lamina propria dendritic cells maintain T cell homeostasis but do not affect commensalism

(2013) Nathan E. Welty et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Retinoic acid controls the homeostasis of pre-cDC–derived splenic and intestinal dendritic cells

(2013) Christopher A. Klebanoff et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Comparative transcriptional and functional profiling defines conserved programs of intestinal DC differentiation in humans and mice

(2013) Payal B Watchmaker et al.   NATURE IMMUNOLOGY

Notch2-dependent classical dendritic cells orchestrate intestinal immunity to attaching-and-effacing bacterial pathogens

(2013) Ansuman T Satpathy et al.   NATURE IMMUNOLOGY

Identification of a unique TGF-β–dependent molecular and functional signature in microglia

(2013) Oleg Butovsky et al.   NATURE NEUROSCIENCE

CD64 distinguishes macrophages from dendritic cells in the gut and reveals the Th1-inducing role of mesenteric lymph node macrophages during colitis

(2012) Samira Tamoutounour et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

GM-CSF Controls Nonlymphoid Tissue Dendritic Cell Homeostasis but Is Dispensable for the Differentiation of Inflammatory Dendritic Cells

(2012) Melanie Greter et al.   IMMUNITY

Interleukin 23 Production by Intestinal CD103+CD11b+ Dendritic Cells in Response to Bacterial Flagellin Enhances Mucosal Innate Immune Defense

(2012) Melissa A. Kinnebrew et al.   IMMUNITY

Identification of Axl as a downstream effector of TGF-β1 during Langerhans cell differentiation and epidermal homeostasis

(2012) Thomas Bauer et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Dendritic Cell-Specific Disruption of TGF-  Receptor II Leads to Altered Regulatory T Cell Phenotype and Spontaneous Multiorgan Autoimmunity

(2012) R. Ramalingam et al.   JOURNAL OF IMMUNOLOGY

Intestinal CD103− dendritic cells migrate in lymph and prime effector T cells

(2012) V Cerovic et al.   Mucosal Immunology

Deciphering the transcriptional network of the dendritic cell lineage

(2012) Jennifer C Miller et al.   NATURE IMMUNOLOGY

Autocrine/paracrine TGF- 1 inhibits Langerhans cell migration

(2012) A. Bobr et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Notch2 Receptor Signaling Controls Functional Differentiation of Dendritic Cells in the Spleen and Intestine

(2011) Kanako L. Lewis et al.   IMMUNITY

CD200 receptor and macrophage function in the intestine

(2011) Calum C. Bain et al.   IMMUNOBIOLOGY

Evidence that Cd101 Is an Autoimmune Diabetes Gene in Nonobese Diabetic Mice

(2011) D. B. Rainbow et al.   JOURNAL OF IMMUNOLOGY

Functional Specializations of Intestinal Dendritic Cell and Macrophage Subsets That Control Th17 and Regulatory T Cell Responses Are Dependent on the T Cell/APC Ratio, Source of Mouse Strain, and Regional Localization

(2011) T. L. Denning et al.   JOURNAL OF IMMUNOLOGY

Conditional Deletion of TGF-βR1 Using Langerin-Cre Mice Results in Langerhans Cell Deficiency and Reduced Contact Hypersensitivity

(2011) Sonja P. Zahner et al.   JOURNAL OF IMMUNOLOGY

A New Subset of CD103+CD8 + Dendritic Cells in the Small Intestine Expresses TLR3, TLR7, and TLR9 and Induces Th1 Response and CTL Activity

(2011) K. Fujimoto et al.   JOURNAL OF IMMUNOLOGY

Cutting Edge: Expression of XCR1 Defines Mouse Lymphoid-Tissue Resident and Migratory Dendritic Cells of the CD8 + Type

(2011) K. Crozat et al.   JOURNAL OF IMMUNOLOGY

Fate mapping of IL-17-producing T cells in inflammatory responses

(2011) Keiji Hirota et al.   NATURE IMMUNOLOGY

TGF-  Is Required To Maintain the Pool of Immature Langerhans Cells in the Epidermis

(2010) J. M. Kel et al.   JOURNAL OF IMMUNOLOGY

T-cell regulation of neutrophil infiltrate at the early stages of a murine colitis model

(2009) Pieter P.E. van Lierop et al.   INFLAMMATORY BOWEL DISEASES

Regulation of humoral and cellular gut immunity by lamina propria dendritic cells expressing Toll-like receptor 5

(2008) Satoshi Uematsu et al.   NATURE IMMUNOLOGY