Enantioselective Rhodium-Catalyzed Addition of Arylboroxines to N-Unprotected Ketimines: Efficient Synthesis of Cipargamin

P-Chiral Phosphorus Ligands Based on a 2,3-Dihydrobenzo[d][1,3]oxaphosphole Motif for Asymmetric Catalysis

(2019) Guangqing Xu et al.   ACCOUNTS OF CHEMICAL RESEARCH

Stereoelectronic Effect in Ligand Design: Enantioselective Rh-Catalyzed Hydrogenation of Alkyl Cyclic Tetrasubstituted Enamides and Concise Synthesis of (R)-Tofacitinib

(2019) Wenjun Tang   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Catalytic synthesis of 3-aminooxindoles via addition to isatin imine: an update

(2018) Jasneet Kaur et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Highly enantioselective synthesis of α-tertiary chiral amino acid derivatives through rhodium-catalyzed asymmetric arylation of cyclic N-sulfonyl α-ketimino esters

(2018) Zheng Wang et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Enantioselective synthesis of gem-diarylalkanes by transition metal-catalyzed asymmetric arylations (TMCAAr)

(2018) Tao Jia et al.   Chemical Science

Ni(II)-catalyzed asymmetric alkenylations of ketimines

(2018) Mao Quan et al.   Nature Communications

Pd(ii), Ni(ii) and Co(ii)-catalyzed enantioselective additions of organoboron reagents to ketimines

(2018) Mao Quan et al.   CHEMICAL COMMUNICATIONS

N-Sulfonyl Bisimidazoline Ligands and Their Applications in Pd(II)-Catalyzed Asymmetric Addition toward α-Tertiary Amines

(2018) Jia-Yin Wang et al.   ORGANIC LETTERS

Malaria medicine box expands

(2018) Asher Mullard   NATURE REVIEWS DRUG DISCOVERY

Catalytic diastereo- and enantioselective additions of versatile allyl groups to N–H ketimines

(2017) Hwanjong Jang et al.   Nature Chemistry

Highly enantioselective Rh/chiral sulfur-olefin-catalyzed arylation of alkyl-substituted non-benzofused cyclic N-sulfonyl ketimines

(2017) Ming-Qing Liu et al.   Organic Chemistry Frontiers

Highly Enantioselective Rhodium-Catalyzed Addition of Arylboroxines to Simple Aryl Ketones: Efficient Synthesis of Escitalopram

(2016) Linwei Huang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Palladium-Catalyzed Asymmetric Arylation of Trifluoromethylated/Perfluoroalkylated 2-Quinazolinones with High Enantioselectivity

(2016) Bo Zhou et al.   CHEMISTRY-A EUROPEAN JOURNAL

Rhodium-Catalyzed Enantioselective Arylation of Aliphatic Imines

(2016) Naoya Kato et al.   CHEMISTRY-A EUROPEAN JOURNAL

Construction of Cyclic Sulfamidates Bearing Two gem-Diaryl Stereocenters through a Rhodium-Catalyzed Stepwise Asymmetric Arylation Protocol

(2016) Yu-Fang Zhang et al.   ORGANIC LETTERS

Exogenous-Base-Free Palladacycle-Catalyzed Highly Enantioselective Arylation of Imines with Arylboroxines

(2015) Carmen Schrapel et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Organocatalytic Asymmetric Addition of Naphthols and Electron-Rich Phenols to Isatin-Derived Ketimines: Highly Enantioselective Construction of Tetrasubstituted Stereocenters

(2015) Marc Montesinos-Magraner et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Regio- and Enantioselective Aza-Diels-Alder Reactions of 3-Vinylindoles: A Concise Synthesis of the Antimalarial Spiroindolone NITD609

(2015) Haifeng Zheng et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Core-structure-inspired asymmetric addition reactions: enantioselective synthesis of dihydrobenzoxazinone- and dihydroquinazolinone-based anti-HIV agents

(2015) Shen Li et al.   CHEMICAL SOCIETY REVIEWS

Rhodium-catalyzed asymmetric addition of arylboronic acids to cyclic N-sulfonyl ketimines towards the synthesis of α,α-diaryl-α-amino acid derivatives

(2015) Ryosuke Takechi et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Stereoselective Total Synthesis of KAE609 via Direct Catalytic Asymmetric Alkynylation to Ketimine

(2015) Hisashi Takada et al.   ORGANIC LETTERS

Enantioselective Rh(I)-Catalyzed Addition of Arylboronic Acids to Cyclic Ketimines

(2015) Jongrock Kong et al.   ORGANIC LETTERS

Rhodium-Catalyzed Asymmetric Arylation of Cyclic N-Sulfonyl Aryl Alkyl Ketimines: Efficient Access to Highly Enantioenriched α-Tertiary Amines

(2015) Tao Jiang et al.   ORGANIC LETTERS

Pyridine–Hydrazones as N,N′-Ligands in Asymmetric Catalysis: Pd(II)-Catalyzed Addition of Boronic Acids to Cyclic Sulfonylketimines

(2015) Yolanda Álvarez-Casao et al.   ORGANIC LETTERS

Pd(II)-Catalyzed Asymmetric Addition of Arylboronic Acids to Isatin-Derived Ketimines

(2015) Qun He et al.   ORGANIC LETTERS

Simple Open-Chain Phosphite-Olefin as Ligand for Rh-Catalyzed Asymmetric Arylation of Cyclic Ketimines: Enantioselective Access to gem-Diaryl α-Amino Acid Derivatives

(2015) Yi Li et al.   ACS Catalysis

Pd(ii)-catalyzed asymmetric addition of arylboronic acids to cyclic N-sulfonyl ketimine esters and a DFT study of its mechanism

(2015) Mao Quan et al.   Organic Chemistry Frontiers

High Performance of a Palladium Phosphinooxazoline Catalyst in the Asymmetric Arylation of CyclicN-Sulfonyl Ketimines

(2014) Chunhui Jiang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Treatment of postmenopausal osteoporosis with odanacatib

(2014) Roland D Chapurlat   EXPERT OPINION ON PHARMACOTHERAPY

Enantioselective Rhodium-Catalyzed Arylation of Cyclic N-Sulfamidate Alkylketimines: A New Access to Chiral β-Alkyl-β-aryl Amino Alcohols

(2014) Ya-Jing Chen et al.   ORGANIC LETTERS

Rhodium-Catalyzed Highly Enantioselective Arylation of Cyclic Diketimines: Efficient Synthesis of Chiral Tetrasubstituted 1,2,5-Thiadiazoline 1,1-Dioxides

(2014) Hui Wang et al.   ORGANIC LETTERS

Enantioselective Rhodium-Catalyzed Addition of Arylboronic Acids to Trifluoromethyl Ketones

(2013) Renshi Luo et al.   ADVANCED SYNTHESIS & CATALYSIS

A Palladium-Catalyzed Enantioselective Addition of Arylboronic Acids to Cyclic Ketimines

(2013) Guoqiang Yang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Design of Phosphorus Ligands with Deep Chiral Pockets: Practical Synthesis of Chiral β-Arylamines by Asymmetric Hydrogenation

(2013) Guodu Liu et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Hydroxorhodium/Chiral Diene Complexes as Effective Catalysts for the Asymmetric Arylation of 3-Aryl-3-hydroxyisoindolin-1-ones

(2013) Takahiro Nishimura et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Rhodium-Catalyzed Dynamic Kinetic Asymmetric Transformations of Racemic Allenes by the [3+2] Annulation of Aryl Ketimines

(2013) Duc N. Tran et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Asymmetric synthesis of gem-diaryl substituted cyclic sulfamidates and sulfamides by rhodium-catalyzed arylation of cyclic ketimines

(2013) Takahiro Nishimura et al.   CHEMICAL COMMUNICATIONS

Highly Enantioselective Decarboxylative Mannich Reaction of Malonic Acid Half Oxyesters with Cyclic Trifluoromethyl Ketimines: Synthesis of β-Amino Esters and Anti-HIV Drug DPC 083

(2013) Hai-Na Yuan et al.   CHEMISTRY-A EUROPEAN JOURNAL

Simple Branched Sulfur–Olefins as Chiral Ligands for Rh-Catalyzed Asymmetric Arylation of Cyclic Ketimines: Highly Enantioselective Construction of Tetrasubstituted Carbon Stereocenters

(2013) Hui Wang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

The P-Chiral Phosphane Ligand (MeO-BIBOP) for Efficient and Practical Large-Scale Rh-Catalyzed Asymmetric Hydrogenation of N-Acetyl Enamides with High TONs

(2013) Wenjie Li et al.   ORGANIC PROCESS RESEARCH & DEVELOPMENT

Asymmetric Synthesis of (Triaryl)methylamines by Rhodium-Catalyzed Addition of Arylboroxines to Cyclic N-Sulfonyl Ketimines

(2012) Takahiro Nishimura et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Organocatalytic Asymmetric α-Amination of Unprotected 3-Aryl and 3-Aliphatic Substituted Oxindoles using Di-tert-butyl Azodicarboxylate

(2011) Feng Zhou et al.   ADVANCED SYNTHESIS & CATALYSIS

Enantioselective Rhodium(I)-Catalyzed [3+2] Annulations of Aromatic Ketimines Induced by Directed CH Activations

(2011) Duc N. Tran et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Bifunctional Cinchona Alkaloid Thiourea Catalyzed Highly Efficient, Enantioselective Aza-Henry Reaction of Cyclic Trifluoromethyl Ketimines: Synthesis of Anti-HIV Drug DPC 083

(2011) Hexin Xie et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Advances in the Catalytic Asymmetric Arylation of Imines using Organoboron Reagents: An Approach to Chiral Arylamines

(2011) Carolina S. Marques et al.   ChemCatChem

Catalytic Enantioselective Formation of C−C Bonds by Addition to Imines and Hydrazones: A Ten-Year Update

(2011) Shu̅ Kobayashi et al.   CHEMICAL REVIEWS

Highly Functional Group Compatible Rh-Catalyzed Addition of Arylboroxines to ActivatedN-tert-Butanesulfinyl Ketimines

(2011) Hyung Hoon Jung et al.   ORGANIC LETTERS

Rhodium-Catalyzed Asymmetric Addition of Potassium Organotrifluoroborates toN-Sulfonyl Ketimines

(2011) Ryo Shintani et al.   ORGANIC LETTERS

Copper Catalyzed Asymmetric Propargylation of Aldehydes

(2010) Daniel R. Fandrick et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Rhodium-Catalyzed Asymmetric Arylation ofN-Tosyl Ketimines

(2010) Ryo Shintani et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Spiroindolones, a Potent Compound Class for the Treatment of Malaria

(2010) M. Rottmann et al.   SCIENCE

Novel, Tunable, and Efficient Chiral Bisdihydrobenzooxaphosphole Ligands for Asymmetric Hydrogenation

(2009) Wenjun Tang et al.   ORGANIC LETTERS

Asymmetric Synthesis of Tertiary Alcohols and α-Tertiary Amines via Cu-Catalyzed C−C Bond Formation to Ketones and Ketimines

(2008) Masakatsu Shibasaki et al.   CHEMICAL REVIEWS