Organocatalytic Asymmetric Addition of Naphthols and Electron-Rich Phenols to Isatin-Derived Ketimines: Highly Enantioselective Construction of Tetrasubstituted Stereocenters

Enantioselective Construction of Vicinal Tetrasubstituted Stereocenters by the Mannich Reaction of Silyl Ketene Imines with Isatin-Derived Ketimines

(2014) Jiannan Zhao et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Highly enantioselective aza-Henry reaction with isatin N-Boc ketimines

(2014) Melireth Holmquist et al.   CHEMICAL COMMUNICATIONS

Organocatalyzed Enantioselective Mannich Reaction of Pyrazoleamides with Isatin-Derived Ketimines

(2014) Tian-Ze Li et al.   JOURNAL OF ORGANIC CHEMISTRY

N,N′-Dioxide–Scandium(III)-Catalyzed Asymmetric Aza-Friedel–Crafts Reaction of Sesamol with Aldimines

(2014) Sha Bai et al.   JOURNAL OF ORGANIC CHEMISTRY

C3-Symmetric chiral trisimidazoline-catalyzed Friedel–Crafts (FC)-type reaction

(2014) Shinobu Takizawa et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

N-Heterocyclic Carbene-Catalyzed Chemoselective Cross-Aza-Benzoin Reaction of Enals with Isatin-Derived Ketimines: Access to Chiral Quaternary Aminooxindoles

(2014) Jianfeng Xu et al.   ORGANIC LETTERS

Bis(imidazolidine)pyridine-NiCl2 Catalyst for Nitro-Mannich Reaction of Isatin-Derived N-Boc Ketimines: Asymmetric Synthesis of Chiral 3-Substituted 3-Amino-2-oxindoles

(2014) Takayoshi Arai et al.   ORGANIC LETTERS

Organocatalytic asymmetric Friedel–Crafts reaction of 1-naphthols with isatins: an enantioselective synthesis of 3-aryl-3-hydroxy-2-oxindoles

(2014) Jasneet Kaur et al.   TETRAHEDRON LETTERS

Organocatalytic enantioselective aza-Henry reaction of ketimines derived from isatins: access to optically active 3-amino-2-oxindoles

(2014) Akshay Kumar et al.   RSC Advances

An Organocatalytic Addition of Nitromethane to Activated Ketimines

(2014) Yu-Hui Wang et al.   Asian Journal of Organic Chemistry

Chiral Phosphoric Acid-Catalyzed Asymmetric Aza-Friedel-Crafts Reaction of Indoles with CyclicN-Acylketimines: Enantioselective Synthesis of Trifluoromethyldihydroquinazolines

(2013) Ke-Feng Zhang et al.   ADVANCED SYNTHESIS & CATALYSIS

Organocatalytic asymmetric synthesis of 3,3-disubstituted oxindoles featuring two heteroatoms at the C3 position

(2013) Feng Zhou et al.   CHEMICAL COMMUNICATIONS

Catalytic Enantioselective Allylation of Ketimines by Using Palladium Pincer Complexes with Chiral Bis(imidazoline)s

(2013) Shuichi Nakamura et al.   CHEMISTRY-A EUROPEAN JOURNAL

Enantioselective Squaramide-Catalysed Domino Mannich-Cyclization Reaction of Isatin Imines

(2013) Xi-Bo Wang et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

Asymmetric catalytic aza-Morita–Baylis–Hillman reaction for the synthesis of 3-substituted-3-aminooxindoles with chiral quaternary carbon centers

(2013) Fang-Le Hu et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

First example of quinine-squaramide catalyzed enantioselective addition of diphenyl phosphite to ketimines derived from isatins

(2013) Jimil George et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Organocatalytic asymmetric Michael addition of 2-naphthols to alkylideneindolenines generated in situ from arenesulfonylalkylindoles

(2013) Liangliang Yu et al.   TETRAHEDRON LETTERS

Organocatalytic enantioselective aza-Friedel–Crafts reaction of sesamols with N-sulfonylimines catalyzed by 6′-OH Cinchona alkaloids

(2013) Pankaj Chauhan et al.   TETRAHEDRON LETTERS

Organocatalytic asymmetric synthesis of 3-amino-2-oxindole derivatives bearing a tetra-substituted stereocenter

(2013) Pankaj Chauhan et al.   TETRAHEDRON-ASYMMETRY

Organocatalytic Enantioselective Friedel-Crafts Reaction of 1-Naphthols with Isatins and an Unexpected Spontaneous Dehydration Process

(2013) Deyan Wu et al.   Asian Journal of Organic Chemistry

A Novel Method for Synthesizing N-Alkoxycarbonyl Aryl α-Imino Esters and Their Applications in Enantioselective Transformations

(2012) Yu Qian et al.   ADVANCED SYNTHESIS & CATALYSIS

Iminium ion catalysis: the enantioselective Friedel–Crafts alkylation–acetalization cascade of naphthols with α,β-unsaturated cyclic ketones

(2012) Enrico Paradisi et al.   CHEMICAL COMMUNICATIONS

The highly enantioselective addition of indoles and pyrroles to isatins-derived N-Boc ketimines catalyzed by chiral phosphoric acids

(2012) Jingchao Feng et al.   CHEMICAL COMMUNICATIONS

Organocatalytic asymmetric cyanation of isatin derived N-Boc ketoimines

(2012) Yun-Lin Liu et al.   CHEMICAL COMMUNICATIONS

Enantioselective Synthesis of AG-041R by using N-Heteroarenesulfonyl Cinchona Alkaloid Amides as Organocatalysts

(2012) Noriyuki Hara et al.   CHEMISTRY-A EUROPEAN JOURNAL

Vanadium-catalyzed enantioselective Friedel–Crafts-type reactions

(2012) Shinobu Takizawa et al.   DALTON TRANSACTIONS

Highly Enantioselective Addition of Enals to Isatin-Derived Ketimines Catalyzed by N-Heterocyclic Carbenes: Synthesis of Spirocyclic γ-Lactams

(2012) Hui Lv et al.   ORGANIC LETTERS

Synthesis of N-Alkoxycarbonyl Ketimines Derived from Isatins and Their Application in Enantioselective Synthesis of 3-Aminooxindoles

(2012) Wenjin Yan et al.   ORGANIC LETTERS

Organocatalytic Asymmetric α-Amination of Unprotected 3-Aryl and 3-Aliphatic Substituted Oxindoles using Di-tert-butyl Azodicarboxylate

(2011) Feng Zhou et al.   ADVANCED SYNTHESIS & CATALYSIS

Asymmetric Brønsted Acid-Catalyzed Friedel-Crafts Reactions of Indoles with Cyclic Imines - Efficient Generation of Nitrogen-Substituted Quaternary Carbon Centers

(2011) Magnus Rueping et al.   ADVANCED SYNTHESIS & CATALYSIS

Facile and Efficient Enantioselective Hydroxyamination Reaction: Synthesis of 3-Hydroxyamino-2-Oxindoles Using Nitrosoarenes

(2011) Ke Shen et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Potent and selective oxindole-based vasopressin 1b receptor antagonists with improved pharmacokinetic properties

(2011) Thorsten Oost et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Highly enantioselective Friedel–Crafts alkylation reaction catalyzed by rosin-derived tertiary amine–thiourea: synthesis of modified chromanes with anticancer potency

(2011) Xianxing Jiang et al.   CHEMICAL COMMUNICATIONS

Catalytic Enantioselective Formation of C−C Bonds by Addition to Imines and Hydrazones: A Ten-Year Update

(2011) Shu̅ Kobayashi et al.   CHEMICAL REVIEWS

Squaramides: Bridging from Molecular Recognition to Bifunctional Organocatalysis

(2011) José Alemán et al.   CHEMISTRY-A EUROPEAN JOURNAL

Asymmetric Organocatalytic Aza-Friedel-Crafts Reaction of Naphthols with N-Sulfonyl Imines

(2011) Pankaj Chauhan et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

Transition-Metal-Mediated Routes to 3,3-Disubstituted Oxindoles through Anilide Cyclisation

(2011) Johannes E. M. N. Klein et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

Enantioselective Synthesis of Tertiary Alcohols through a Zirconium-Catalyzed Friedel–Crafts Alkylation of Pyrroles with α-Ketoesters

(2011) Gonzalo Blay et al.   JOURNAL OF ORGANIC CHEMISTRY

Dinuclear zinc catalyzed asymmetric Friedel–Crafts amidoalkylation of indoles with aryl aldimines

(2011) Bei-Lei Wang et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Enantioselective organocatalytic oxyamination of unprotected 3-substituted oxindoles

(2011) Xavier Companyó et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Asymmetric hydroxyamination of oxindoles catalyzed by chiral bifunctional tertiary aminethiourea: construction of 3-amino-2-oxindoles with quaternary stereocenters

(2011) Li-Na Jia et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Enantioselective Organocatalytic Synthesis of Quaternary α-Amino Acids Bearing a CF3Moiety

(2011) Ralph Husmann et al.   ORGANIC LETTERS

Organocatalytic Enantioselective Friedel−Crafts Reactions of 1-Naphthols with Aldimines

(2011) Guixia Liu et al.   ORGANIC LETTERS

Highly enantioselective Friedel–Crafts reaction of indoles with N-sulfonyl aldimines catalyzed by heteroarylidene malonate-type bis(oxazoline) copper(II) complexes

(2011) Lei Liu et al.   TETRAHEDRON-ASYMMETRY

Recent progress in enantioselective synthesis of C3-functionalized oxindoles: rare earth metals take action

(2011) Ke Shen et al.   Chemical Science

Enantioselective Organocatalytic Synthesis of Arylglycines via Friedel-Crafts Alkylation of Arenes with a Glyoxylate Imine

(2010) Dieter Enders et al.   ADVANCED SYNTHESIS & CATALYSIS

Catalytic Asymmetric Synthesis of Oxindoles Bearing a Tetrasubstituted Stereocenter at the C-3 Position

(2010) Feng Zhou et al.   ADVANCED SYNTHESIS & CATALYSIS

Entropy-Controlled Catalytic Asymmetric 1,4-Type Friedel-Crafts Reaction of Phenols Using Conformationally Flexible Guanidine/Bisthiourea Organocatalyst

(2010) Yoshihiro Sohtome et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Squaramide-catalyzed enantioselective Friedel–Crafts reaction of indoles with imines

(2010) Yong Qian et al.   CHEMICAL COMMUNICATIONS

Spirotetrahydro β-Carbolines (Spiroindolones): A New Class of Potent and Orally Efficacious Compounds for the Treatment of Malaria

(2010) Bryan K. S. Yeung et al.   JOURNAL OF MEDICINAL CHEMISTRY

Catalytic Asymmetric Synthesis of 3-Aminooxindoles: Enantiofacial Selectivity Switch in Bimetallic vs Monometallic Schiff Base Catalysis

(2010) Shinsuke Mouri et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

A facile method for the synthesis of oxindole based quaternary α-aminonitriles via the Strecker reaction

(2010) Yun-Lin Liu et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Highly Enantioselective Organocatalytic α-Amination Reactions of Aryl Oxindoles: Developing Designer Multifunctional Alkaloid Catalysts

(2010) Tommy Bui et al.   ORGANIC LETTERS

Spiroindolones, a Potent Compound Class for the Treatment of Malaria

(2010) M. Rottmann et al.   SCIENCE

Cinchona Alkaloids in Asymmetric Organocatalysis

(2010) Tommaso Marcelli et al.   SYNTHESIS-STUTTGART

Asymmetric organocatalytic N-nitroso-aldol reaction of oxindoles

(2010) Tao Zhang et al.   TETRAHEDRON-ASYMMETRY

Asymmetric construction of quaternary stereocenters by direct organocatalytic amination of 3-substituted oxindoles

(2009) Zi-Qing Qian et al.   CHEMICAL COMMUNICATIONS

Expanding the Scope of Cinchona Alkaloid-Catalyzed Enantioselective α-Aminations of Oxindoles: A Versatile Approach to Optically Active 3-Amino-2-oxindole Derivatives

(2009) Tommy Bui et al.   JOURNAL OF ORGANIC CHEMISTRY

Organocatalytic Asymmetric Friedel−Crafts Alkylation/Cyclization Cascade Reaction of 1-Naphthols and α,β-Unsaturated Aldehydes: An Enantioselective Synthesis of Chromanes and Dihydrobenzopyranes

(2009) Liang Hong et al.   JOURNAL OF ORGANIC CHEMISTRY

Highly Enantioselective and Organocatalytic α-Amination of 2-Oxindoles

(2009) Liang Cheng et al.   ORGANIC LETTERS

Asymmetric Brønsted Acid Catalyzed Nucleophilic Addition to in situ Generated Chiral N-Acyliminium Ions

(2009) Magnus Rueping et al.   SYNLETT

Organocatalyzed Friedel–Craft-type reaction of 2-naphthol with β,γ-unsaturated α-keto ester to form novel optically active naphthopyran derivatives

(2009) Xiao-Sheng Wang et al.   TETRAHEDRON-ASYMMETRY

Chiral Brønsted Acid‐Mediated Enantioselective Organocatalytic Three‐Component Reaction for the Construction of Trifluoromethyl‐Containing Molecules

(2008) Guang‐Wu Zhang et al.   ADVANCED SYNTHESIS & CATALYSIS

9-Thiourea Cinchona alkaloid supported on mesoporous silica as a highly enantioselective, recyclable heterogeneous asymmetric catalyst

(2008) Peng Yu et al.   CHEMICAL COMMUNICATIONS

Highly Enantioselective Friedel–Crafts Reaction of 4,7-Dihydroindoles with Imines by Chiral Phosphoric Acids: Facile Access to 2-Indolyl Methanamine Derivatives

(2008) Qiang Kang et al.   CHEMISTRY-A EUROPEAN JOURNAL

Non-peptide arginine-vasopressin antagonists: the vaptans

(2008) Guy Decaux et al.   LANCET

Enantioselective Zirconium-Catalyzed Friedel−Crafts Alkylation of Pyrrole with Trifluoromethyl Ketones

(2008) Gonzalo Blay et al.   ORGANIC LETTERS

Enantioselective synthesis of naphthopyran derivatives catalyzed by bifunctional thiourea-tertiary amines

(2008) Xiao-Sheng Wang et al.   TETRAHEDRON-ASYMMETRY