Sodium, hypertension, and the gut: does the gut microbiota go salty?

The Short-Chain Fatty Acid Propionate Protects from Hypertensive Cardiovascular Damage

(2019) Hendrik Bartolomaeus et al.   CIRCULATION

A new genomic blueprint of the human gut microbiota

(2019) Alexandre Almeida et al.   NATURE

Heart Disease and Stroke Statistics—2019 Update: A Report From the American Heart Association

(2019) Emelia J. Benjamin et al.   CIRCULATION

Role of the immune system in vascular function and blood pressure control induced by fecal microbiota transplantation in rats

(2019) Marta Toral et al.   Acta Physiologica

Early Time-Restricted Feeding Improves Insulin Sensitivity, Blood Pressure, and Oxidative Stress Even without Weight Loss in Men with Prediabetes

(2018) Elizabeth F. Sutton et al.   Cell Metabolism

Imbalance of gut microbiome and intestinal epithelial barrier dysfunction in patients with high blood pressure

(2018) Seungbum Kim et al.   CLINICAL SCIENCE

2017 ACC/AHA/AAPA/ABC/ACPM/AGS/APhA/ASH/ASPC/NMA/PCNA Guideline for the Prevention, Detection, Evaluation, and Management of High Blood Pressure in Adults

(2018) Paul K. Whelton et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Differential metabolic effects of oral butyrate treatment in lean versus metabolic syndrome subjects

(2018) KEC Bouter et al.   Clinical and Translational Gastroenterology

High salt diet exacerbates colitis in mice by decreasing Lactobacillus levels and butyrate production

(2018) Pedro M. Miranda et al.   Microbiome

Disparate Effects of Antibiotics on Hypertension

(2018) Sarah Galla et al.   PHYSIOLOGICAL GENOMICS

Maternal Administration of Probiotic or Prebiotic Prevents Male Adult Rat Offspring against Developmental Programming of Hypertension Induced by High Fructose Consumption in Pregnancy and Lactation

(2018) Chien-Ning Hsu et al.   Nutrients

A High Salt Diet Modulates the Gut Microbiota and Short Chain Fatty Acids Production in a Salt-Sensitive Hypertension Rat Model

(2018) Ariel Bier et al.   Nutrients

Prebiotics, Probiotics, and Acetate Supplementation Prevent Hypertension in a Model of Obstructive Sleep Apnea

(2018) Bhanu P. Ganesh et al.   HYPERTENSION

Attenuation of Microbiotal Dysbiosis and Hypertension in a CRISPR/Cas9 Gene Ablation Rat Model of GPER1

(2018) Harshal Waghulde et al.   HYPERTENSION

Timing the Microbes: The Circadian Rhythm of the Gut Microbiome

(2017) Xue Liang et al.   JOURNAL OF BIOLOGICAL RHYTHMS

Salt-responsive gut commensal modulates TH17 axis and disease

(2017) Nicola Wilck et al.   NATURE

Alterations in the gut microbiota can elicit hypertension in rats

(2017) Sareema Adnan et al.   PHYSIOLOGICAL GENOMICS

High-Salt Diet Has a Certain Impact on Protein Digestion and Gut Microbiota: A Sequencing and Proteome Combined Study

(2017) Chao Wang et al.   Frontiers in Microbiology

Gut microbiota dysbiosis contributes to the development of hypertension

(2017) Jing Li et al.   Microbiome

Are We Really Vastly Outnumbered? Revisiting the Ratio of Bacterial to Host Cells in Humans

(2016) Ron Sender et al.   CELL

High-Fiber Diet and Acetate Supplementation Change the Gut Microbiota and Prevent the Development of Hypertension and Heart Failure in Hypertensive MiceClinical Perspective

(2016) Francine Z. Marques et al.   CIRCULATION

Systemic availability and metabolism of colonic-derived short-chain fatty acids in healthy subjects: a stable isotope study

(2016) Eef Boets et al.   JOURNAL OF PHYSIOLOGY-LONDON

Intracolonic hydrogen sulfide lowers blood pressure in rats

(2016) Lenka Tomasova et al.   NITRIC OXIDE-BIOLOGY AND CHEMISTRY

Microbial short chain fatty acid metabolites lower blood pressure via endothelial G protein-coupled receptor 41

(2016) Niranjana Natarajan et al.   PHYSIOLOGICAL GENOMICS

Reduced Epithelial Na+/H+ Exchange Drives Gut Microbial Dysbiosis and Promotes Inflammatory Response in T Cell-Mediated Murine Colitis

(2016) Daniel Laubitz et al.   PLoS One

Gut Microbiota Promote Angiotensin II–Induced Arterial Hypertension and Vascular Dysfunction

(2016) Susanne H. Karbach et al.   Journal of the American Heart Association

Western diet induces a shift in microbiota composition enhancing susceptibility to Adherent-Invasive E. coli infection and intestinal inflammation.

(2016) Allison Agus et al.   Scientific Reports

Effects of Diurnal Variation of Gut Microbes and High-Fat Feeding on Host Circadian Clock Function and Metabolism

(2015) Vanessa Leone et al.   Cell Host & Microbe

Role of the Gut Microbiome in Obstructive Sleep Apnea–Induced Hypertension

(2015) David J. Durgan et al.   HYPERTENSION

Gut Dysbiosis Is Linked to HypertensionNovelty and Significance

(2015) Tao Yang et al.   HYPERTENSION

Estimating Sodium and Potassium Intakes and Their Ratio in the American Diet: Data from the 2011–2012 NHANES

(2015) Regan L Bailey et al.   JOURNAL OF NUTRITION

Gut biogeography of the bacterial microbiota

(2015) Gregory P. Donaldson et al.   NATURE REVIEWS MICROBIOLOGY

Evidence for a link between gut microbiota and hypertension in the Dahl rat

(2015) Blair Mell et al.   PHYSIOLOGICAL GENOMICS

Rhythmicity of the intestinal microbiota is regulated by gender and the host circadian clock

(2015) Xue Liang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Effects of dietary salt levels on monocytic cells and immune responses in healthy human subjects: a longitudinal study

(2015) Buqing Yi et al.   Translational Research

Bile Acid-Activated Receptors, Intestinal Microbiota, and the Treatment of Metabolic Disorders

(2015) Stefano Fiorucci et al.   TRENDS IN MOLECULAR MEDICINE

The Gut Microbiota of Rural Papua New Guineans: Composition, Diversity Patterns, and Ecological Processes

(2015) Inés Martínez et al.   Cell Reports

Clock genes in hypertension

(2014) Jacob Richards et al.   BLOOD PRESSURE MONITORING

Effect of Probiotics on Blood Pressure

(2014) Saman Khalesi et al.   HYPERTENSION

The International Scientific Association for Probiotics and Prebiotics consensus statement on the scope and appropriate use of the term probiotic

(2014) Colin Hill et al.   Nature Reviews Gastroenterology & Hepatology

Aldosterone mediates its rapid effects in vascular endothelial cells through GPER activation

(2013) Robert Gros et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Loss of NHE3 alters gut microbiota composition and influences Bacteroides thetaiotaomicron growth

(2013) Melinda A. Engevik et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Microbial regulation of host hydrogen sulfide bioavailability and metabolism

(2013) Xinggui Shen et al.   FREE RADICAL BIOLOGY AND MEDICINE

2013 AHA/ACC Guideline on Lifestyle Management to Reduce Cardiovascular Risk

(2013) Robert H. Eckel et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Diet rapidly and reproducibly alters the human gut microbiome

(2013) Lawrence A. David et al.   NATURE

Sodium chloride drives autoimmune disease by the induction of pathogenic TH17 cells

(2013) Markus Kleinewietfeld et al.   NATURE

Olfactory receptor responding to gut microbiota-derived signals plays a role in renin secretion and blood pressure regulation

(2013) Jennifer L. Pluznick et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Metagenomics and novel gene discovery

(2013) Eamonn P Culligan et al.   Virulence

Antihypertensive and Laxative Effects by Pharmacological Inhibition of Sodium-Proton-Exchanger Subtype 3–Mediated Sodium Absorption in the Gut

(2012) Dominik Linz et al.   HYPERTENSION

Microbiota-induced IL-1β, but not IL-6, is critical for the development of steady-state TH17 cells in the intestine

(2012) Michael H. Shaw et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Structure, function and diversity of the healthy human microbiome

(2012)   NATURE

Short-chain fatty acids and ketones directly regulate sympathetic nervous system via G protein-coupled receptor 41 (GPR41)

(2011) I. Kimura et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A human gut microbial gene catalogue established by metagenomic sequencing

(2010) Junjie Qin et al.   NATURE

Systemic gut microbial modulation of bile acid metabolism in host tissue compartments

(2010) J. R. Swann et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Impact of diet in shaping gut microbiota revealed by a comparative study in children from Europe and rural Africa

(2010) C. De Filippo et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Induction of Intestinal Th17 Cells by Segmented Filamentous Bacteria

(2009) Ivaylo I. Ivanov et al.   CELL

Diversity, metabolism and microbial ecology of butyrate-producing bacteria from the human large intestine

(2009) Petra Louis et al.   FEMS MICROBIOLOGY LETTERS

Interleukin 17 Promotes Angiotensin II–Induced Hypertension and Vascular Dysfunction

(2009) Meena S. Madhur et al.   HYPERTENSION

Mechanisms of the Regulation of the IntestinalNa+/H+Exchanger NHE3

(2009) Peijian He et al.   JOURNAL OF BIOMEDICINE AND BIOTECHNOLOGY

Specific Microbiota Direct the Differentiation of IL-17-Producing T-Helper Cells in the Mucosa of the Small Intestine

(2008) Ivaylo I. Ivanov et al.   Cell Host & Microbe

A core gut microbiome in obese and lean twins

(2008) Peter J. Turnbaugh et al.   NATURE