Sodium chloride drives autoimmune disease by the induction of pathogenic TH17 cells

Pathogen-induced human TH17 cells produce IFN-γ or IL-10 and are regulated by IL-1β

(2012) Christina E. Zielinski et al.   NATURE

Transcriptional regulation of gene expression during osmotic stress responses by the mammalian target of rapamycin

(2012) M. Carmen Ortells et al.   NUCLEIC ACIDS RESEARCH

Activation of p38 MAPK in CD4 T cells controls IL-17 production and autoimmune encephalomyelitis

(2011) R. Noubade et al.   BLOOD

The Importance of Population-Wide Sodium Reduction as a Means to Prevent Cardiovascular Disease and Stroke

(2011) Lawrence J. Appel et al.   CIRCULATION

Genetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis

(2011) Stephen Sawcer et al.   NATURE

RORγt drives production of the cytokine GM-CSF in helper T cells, which is essential for the effector phase of autoimmune neuroinflammation

(2011) Laura Codarri et al.   NATURE IMMUNOLOGY

The encephalitogenicity of TH17 cells is dependent on IL-1- and IL-23-induced production of the cytokine GM-CSF

(2011) Mohamed El-Behi et al.   NATURE IMMUNOLOGY

MicroRNA-155 Promotes Autoimmune Inflammation by Enhancing Inflammatory T Cell Development

(2010) Ryan M. O'Connell et al.   IMMUNITY

Hypertonic stress regulates T cell function via pannexin-1 hemichannels and P2X receptors

(2010) Tobias Woehrle et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Generation of pathogenic TH17 cells in the absence of TGF-β signalling

(2010) Kamran Ghoreschi et al.   NATURE

IL-17 and Th17 Cells

(2009) Thomas Korn et al.   Annual Review of Immunology

Transcriptional regulatory networks in Th17 cell differentiation

(2009) Liang Zhou et al.   CURRENT OPINION IN IMMUNOLOGY

Salt intakes around the world: implications for public health

(2009) I. J Brown et al.   INTERNATIONAL JOURNAL OF EPIDEMIOLOGY

Tonicity-dependent induction of Sgk1 expression has a potential role in dehydration-induced natriuresis in rodents

(2009) Songcang Chen et al.   JOURNAL OF CLINICAL INVESTIGATION

RNA Interference Screen in Primary Human T Cells Reveals FLT3 as a Modulator of IL-10 Levels

(2009) A. L. Astier et al.   JOURNAL OF IMMUNOLOGY

C-C chemokine receptor 6–regulated entry of TH-17 cells into the CNS through the choroid plexus is required for the initiation of EAE

(2009) Andrea Reboldi et al.   NATURE IMMUNOLOGY

Macrophages regulate salt-dependent volume and blood pressure by a vascular endothelial growth factor-C–dependent buffering mechanism

(2009) Agnes Machnik et al.   NATURE MEDICINE

Role of the renin-angiotensin system in autoimmune inflammation of the central nervous system

(2009) J. Stegbauer et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Blocking angiotensin-converting enzyme induces potent regulatory T cells and modulates TH1- and TH17-mediated autoimmunity

(2009) M. Platten et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Brx Mediates the Response of Lymphocytes to Osmotic Stress Through the Activation of NFAT5

(2009) T. Kino et al.   Science Signaling

Development of a Small-Molecule Serum- and Glucocorticoid-Regulated Kinase-1 Antagonist and Its Evaluation as a Prostate Cancer Therapeutic

(2008) A. B. Sherk et al.   CANCER RESEARCH

IL-21 and TGF-β are required for differentiation of human TH17 cells

(2008) Li Yang et al.   NATURE

Potential Relevance of α1-Adrenergic Receptor Autoantibodies in Refractory Hypertension

(2008) Katrin Wenzel et al.   PLoS One