Reduced Epithelial Na+/H+ Exchange Drives Gut Microbial Dysbiosis and Promotes Inflammatory Response in T Cell-Mediated Murine Colitis

Human Clostridium difficile infection: inhibition of NHE3 and microbiota profile

(2015) Melinda A. Engevik et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

An Integrative View of Microbiome-Host Interactions in Inflammatory Bowel Diseases

(2015) Marta Wlodarska et al.   Cell Host & Microbe

Findings From a Randomized Controlled Trial of Fecal Transplantation for Patients With Ulcerative Colitis

(2015) Noortje G. Rossen et al.   GASTROENTEROLOGY

Metabolic and metagenomic outcomes from early-life pulsed antibiotic treatment

(2015) Yael R. Nobel et al.   Nature Communications

Development of gut inflammation in mice colonized with mucosa-associated bacteria from patients with ulcerative colitis

(2015) Zhengyu Du et al.   Gut Pathogens

Effect of Exclusive Enteral Nutrition on the Microbiota of Children With Newly Diagnosed Crohn’s Disease

(2015) Nadeem O Kaakoush et al.   Clinical and Translational Gastroenterology

The Treatment-Naive Microbiome in New-Onset Crohn’s Disease

(2014) Dirk Gevers et al.   Cell Host & Microbe

The microbial basis of inflammatory bowel diseases

(2014) Sushila R. Dalal et al.   JOURNAL OF CLINICAL INVESTIGATION

Phenotypic and Functional Analysis of CD4+CD25-Foxp3+ T Cells in Patients with Systemic Lupus Erythematosus

(2014) M. Bonelli et al.   JOURNAL OF IMMUNOLOGY

Reduced colonic microbial diversity is associated with colitis in NHE3-deficient mice

(2013) Claire B. Larmonier et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Loss of NHE3 alters gut microbiota composition and influences Bacteroides thetaiotaomicron growth

(2013) Melinda A. Engevik et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Bacteria penetrate the normally impenetrable inner colon mucus layer in both murine colitis models and patients with ulcerative colitis

(2013) Malin E V Johansson et al.   GUT

IL-22 Deficiency Alters Colonic Microbiota To Be Transmissible and Colitogenic

(2013) L. A. Zenewicz et al.   JOURNAL OF IMMUNOLOGY

Treg induction by a rationally selected mixture of Clostridia strains from the human microbiota

(2013) Koji Atarashi et al.   NATURE

Predictive functional profiling of microbial communities using 16S rRNA marker gene sequences

(2013) Morgan G I Langille et al.   NATURE BIOTECHNOLOGY

Microbiota-induced activation of epithelial IL-6 signaling links inflammasome-driven inflammation with transmissible cancer

(2013) B. Hu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Lactobacillus acidophilus upregulates intestinal NHE3 expression and function

(2012) Varsha Singh et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Ultra-high-throughput microbial community analysis on the Illumina HiSeq and MiSeq platforms

(2012) J Gregory Caporaso et al.   ISME Journal

Tregs are dysfunctional in vivo in a spontaneous murine model of Crohn's disease

(2012) D Ishikawa et al.   Mucosal Immunology

Diversity, stability and resilience of the human gut microbiota

(2012) Catherine A. Lozupone et al.   NATURE

Human Intestinal Lumen and Mucosa-Associated Microbiota in Patients with Colorectal Cancer

(2012) Weiguang Chen et al.   PLoS One

Downregulation of the NHE3-Binding PDZ-Adaptor Protein PDZK1 Expression during Cytokine-Induced Inflammation in Interleukin-10–Deficient Mice

(2012) Henrike Lenzen et al.   PLoS One

Improvement of phylum- and class-specific primers for real-time PCR quantification of bacterial taxa

(2011) Tristano Bacchetti De Gregoris et al.   JOURNAL OF MICROBIOLOGICAL METHODS

T regulatory cells lacking CD25 are increased in MS during relapse

(2010) Moa Fransson et al.   AUTOIMMUNITY

Genetics and Environmental Interactions Shape the Intestinal Microbiome to Promote Inflammatory Bowel Disease Versus Mucosal Homeostasis

(2010) R. Balfour Sartor   GASTROENTEROLOGY

New therapeutic targets in ulcerative colitis: The importance of ion transporters in the human colon

(2010) Klaudia Farkas et al.   INFLAMMATORY BOWEL DISEASES

QIIME allows analysis of high-throughput community sequencing data

(2010) J Gregory Caporaso et al.   NATURE METHODS

Identity of mysterious CD4+CD25-Foxp3+ cells in SLE

(2010) David A Horwitz   ARTHRITIS RESEARCH & THERAPY

Changes in Mucosal Homeostasis Predispose NHE3 Knockout Mice to Increased Susceptibility to DSS-Induced Epithelial Injury

(2009) Pawel R. Kiela et al.   GASTROENTEROLOGY

T-cell regulation of neutrophil infiltrate at the early stages of a murine colitis model

(2009) Pieter P.E. van Lierop et al.   INFLAMMATORY BOWEL DISEASES

Preserved Na+/H+ exchanger isoform 3 expression and localization, but decreased NHE3 function indicate regulatory sodium transport defect in ulcerative colitis†

(2009) Sunil Yeruva et al.   INFLAMMATORY BOWEL DISEASES

The Effect of Diet on the Human Gut Microbiome: A Metagenomic Analysis in Humanized Gnotobiotic Mice

(2009) P. J. Turnbaugh et al.   Science Translational Medicine

Are CD4+CD25-Foxp3+ cells in untreated new-onset lupus patients regulatory T cells?

(2009) Hua-xia Yang et al.   ARTHRITIS RESEARCH & THERAPY

Colonic gene expression profile in NHE3-deficient mice: evidence for spontaneous distal colitis

(2008) Daniel Laubitz et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

T cell transfer model of chronic colitis: concepts, considerations, and tricks of the trade

(2008) Dmitry V. Ostanin et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Microbial Influences in Inflammatory Bowel Diseases

(2008) R. Balfour Sartor   GASTROENTEROLOGY

Molecular bases of impaired water and ion movements in inflammatory bowel diseases

(2008) Olga Martínez-Augustin et al.   INFLAMMATORY BOWEL DISEASES

Downregulation of sodium transporters and NHERF proteins in IBD patients and mouse colitis models: Potential contributors to IBD-associated diarrhea

(2008) Sean Sullivan et al.   INFLAMMATORY BOWEL DISEASES

Suppression of Na+/H+exchanger isoform-3 in human inflammatory bowel disease: Lack of reversal by 5′-aminosalicylate treatment

(2008) Iqbal Siddique et al.   SCANDINAVIAN JOURNAL OF GASTROENTEROLOGY