Early Histone Deacetylase Inhibition Mitigates Ischemia/Reperfusion Brain Injury by Reducing Microglia Activation and Modulating Their Phenotype

Immune cells and CNS physiology: Microglia and beyond

(2018) Geoffrey T. Norris et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Inhibition of histone deacetylase 1 or 2 reduces induced cytokine expression in microglia through a protein synthesis independent mechanism

(2017) Benjamin S. Durham et al.   JOURNAL OF NEUROCHEMISTRY

Opening a New Time Window for Treatment of Stroke by Targeting HDAC2

(2017) Yu-Hui Lin et al.   JOURNAL OF NEUROSCIENCE

Inflammation at the blood-brain barrier: The role of liver X receptors

(2017) NM de Wit et al.   NEUROBIOLOGY OF DISEASE

The biphasic function of microglia in ischemic stroke

(2017) Yuanyuan Ma et al.   PROGRESS IN NEUROBIOLOGY

Histone deacetylase 3 (HDAC 3) as emerging drug target in NF-κB-mediated inflammation

(2016) Niek GJ Leus et al.   CURRENT OPINION IN CHEMICAL BIOLOGY

The histone deacetylase inhibitor, sodium butyrate, exhibits neuroprotective effects for ischemic stroke in middle-aged female rats

(2016) Min Jung Park et al.   Journal of Neuroinflammation

HDAC Inhibitor Sodium Butyrate-Mediated Epigenetic Regulation Enhances Neuroprotective Function of Microglia During Ischemic Stroke

(2016) Radhika Patnala et al.   MOLECULAR NEUROBIOLOGY

Inflammation and Stroke: An Overview

(2016) Josef Anrather et al.   Neurotherapeutics

New tools for studying microglia in the mouse and human CNS

(2016) Mariko L. Bennett et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Functions and mechanisms of microglia/macrophages in neuroinflammation and neurogenesis after stroke

(2016) Xiao-Yi Xiong et al.   PROGRESS IN NEUROBIOLOGY

Microglial M1/M2 polarization and metabolic states

(2015) Ruben Orihuela et al.   BRITISH JOURNAL OF PHARMACOLOGY

Inflammatory Responses in Brain Ischemia

(2015) Masahito Kawabori et al.   CURRENT MEDICINAL CHEMISTRY

Functional differences between microglia and monocytes after ischemic stroke

(2015) Rodney M. Ritzel et al.   Journal of Neuroinflammation

Deep, Quantitative Coverage of the Lysine Acetylome Using Novel Anti-acetyl-lysine Antibodies and an Optimized Proteomic Workflow

(2015) Tanya Svinkina et al.   MOLECULAR & CELLULAR PROTEOMICS

The role of microglia and myeloid immune cells in acute cerebral ischemia

(2015) Corinne Benakis et al.   Frontiers in Cellular Neuroscience

Neurogenesis and Inflammation after Ischemic Stroke: What is Known and Where We Go from Here

(2014) Matthew K Tobin et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

The growing landscape of lysine acetylation links metabolism and cell signalling

(2014) Chunaram Choudhary et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Microglial and macrophage polarization—new prospects for brain repair

(2014) Xiaoming Hu et al.   Nature Reviews Neurology

Optogenetic neuronal stimulation promotes functional recovery after stroke

(2014) M. Y. Cheng et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A quantitative spatiotemporal analysis of microglia morphology during ischemic stroke and reperfusion

(2013) Helena W Morrison et al.   Journal of Neuroinflammation

Inflammatory Cytokines in Experimental and Human Stroke

(2012) Kate Lykke Lambertsen et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Novel therapeutic strategies targeting innate immune responses and early inflammation after stroke

(2012) Takashi Shichita et al.   JOURNAL OF NEUROCHEMISTRY

Temporal Changes in Cell Marker Expression and Cellular Infiltration in a Controlled Cortical Impact Model in Adult Male C57BL/6 Mice

(2012) Xuemei Jin et al.   PLoS One

Valproic Acid Attenuates Blood–Brain Barrier Disruption in a Rat Model of Transient Focal Cerebral Ischemia: The Roles of HDAC and MMP-9 Inhibition

(2010) Zhifei Wang et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

The Science of Stroke: Mechanisms in Search of Treatments

(2010) Michael A. Moskowitz et al.   NEURON

Fate Mapping Analysis Reveals That Adult Microglia Derive from Primitive Macrophages

(2010) F. Ginhoux et al.   SCIENCE

Putting the ‘HAT’ back on survival signalling: the promises and challenges of HDAC inhibition in the treatment of neurological conditions

(2009) Sama F Sleiman et al.   EXPERT OPINION ON INVESTIGATIONAL DRUGS

Lysine Acetylation Targets Protein Complexes and Co-Regulates Major Cellular Functions

(2009) C. Choudhary et al.   SCIENCE

Temporal and Spatial Dynamics of Cerebral Immune Cell Accumulation in Stroke

(2009) Mathias Gelderblom et al.   STROKE

Multiple roles of HDAC inhibition in neurodegenerative conditions

(2009) De-Maw Chuang et al.   TRENDS IN NEUROSCIENCES