The histone deacetylase inhibitor, sodium butyrate, exhibits neuroprotective effects for ischemic stroke in middle-aged female rats

Insulin-Like Growth Factor (IGF)-I Modulates Endothelial Blood-Brain Barrier Function in Ischemic Middle-Aged Female Rats

(2016) Shameena Bake et al.   ENDOCRINOLOGY

Butyrate, neuroepigenetics and the gut microbiome: Can a high fiber diet improve brain health?

(2016) Megan W. Bourassa et al.   NEUROSCIENCE LETTERS

Assessment of Serum UCH-L1 and GFAP in Acute Stroke Patients

(2016) Changhong Ren et al.   Scientific Reports

Histone methylation patterns in astrocytes are influenced by age following ischemia

(2015) Nioka C Chisholm et al.   Epigenetics

Estrogen-IGF-1 interactions in neuroprotection: Ischemic stroke as a case study

(2015) Farida Sohrabji   FRONTIERS IN NEUROENDOCRINOLOGY

Histone Deacetylase Inhibitors Modulate Interleukin 6-dependent CD4+T Cell Polarizationin Vitroandin Vivo

(2014) Rainer Glauben et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Blood Brain Barrier and Neuroinflammation Are Critical Targets of IGF-1-Mediated Neuroprotection in Stroke for Middle-Aged Female Rats

(2014) Shameena Bake et al.   PLoS One

Potential Roles of HDAC Inhibitors in Mitigating Ischemia-induced Brain Damage and Facilitating Endogenous Regeneration and Recovery

(2013) Emily Fessler et al.   CURRENT PHARMACEUTICAL DESIGN

Differential effects of aging and sex on stroke induced inflammation across the lifespan

(2013) Bharti Manwani et al.   EXPERIMENTAL NEUROLOGY

Hemorrhagic Transformation after Ischemic Stroke in Animals and Humans

(2013) Glen C Jickling et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Stroke Neuroprotection: Oestrogen and Insulin-Like Growth Factor-1 Interactions and the Role of Microglia

(2013) F. Sohrabji et al.   JOURNAL OF NEUROENDOCRINOLOGY

Effects of sodium butyrate on oxidative stress and behavioral changes induced by administration of d-AMPH

(2013) Amanda V. Steckert et al.   NEUROCHEMISTRY INTERNATIONAL

Whole-body pharmacokinetics of HDAC inhibitor drugs, butyric acid, valproic acid and 4-phenylbutyric acid measured with carbon-11 labeled analogs by PET

(2013) Sung Won Kim et al.   NUCLEAR MEDICINE AND BIOLOGY

Vitamin D Deficiency Exacerbates Experimental Stroke Injury and Dysregulates Ischemia-Induced Inflammation in Adult Rats

(2012) Robyn Balden et al.   ENDOCRINOLOGY

Alteration of immunologic responses on peripheral blood in the acute phase of ischemic stroke: Blood genomic profiling study

(2012) Seung-Hun Oh et al.   JOURNAL OF NEUROIMMUNOLOGY

The epigenetic effects of butyrate: potential therapeutic implications for clinical practice

(2012) Roberto Berni Canani et al.   Clinical Epigenetics

Attenuation of vascular dementia by sodium butyrate in streptozotocin diabetic rats

(2011) Bhupesh Sharma et al.   PSYCHOPHARMACOLOGY

Potential beneficial effects of butyrate in intestinal and extraintestinal diseases

(2011) Roberto Berni Canani   WORLD JOURNAL OF GASTROENTEROLOGY

Biphasic actions of HMGB1 signaling in inflammation and recovery after stroke

(2010) Kazuhide Hayakawa et al.   Annals of the New York Academy of Sciences

Valproic Acid Attenuates Blood–Brain Barrier Disruption in a Rat Model of Transient Focal Cerebral Ischemia: The Roles of HDAC and MMP-9 Inhibition

(2010) Zhifei Wang et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Estradiol and G1 Reduce Infarct Size and Improve Immunosuppression after Experimental Stroke

(2010) B. Zhang et al.   JOURNAL OF IMMUNOLOGY

Benefits of histone deacetylase inhibitors for acute brain injury: a systematic review of animal studies

(2010) Claire L. Gibson et al.   JOURNAL OF NEUROCHEMISTRY

A high cholesterol diet elevates hippocampal cytokine expression in an age and estrogen-dependent manner in female rats

(2010) Danielle K. Lewis et al.   JOURNAL OF NEUROIMMUNOLOGY

Interleukin 18 in the CNS

(2010) Silvia Alboni et al.   Journal of Neuroinflammation

The Neurotoxic Effects of Estrogen on Ischemic Stroke in Older Female Rats Is Associated with Age-Dependent Loss of Insulin-Like Growth Factor-1

(2010) A. Selvamani et al.   JOURNAL OF NEUROSCIENCE

An age-related sprouting transcriptome provides molecular control of axonal sprouting after stroke

(2010) Songlin Li et al.   NATURE NEUROSCIENCE

Age- and Gender-Specific Prevalence of Cardiovascular Risk Factors in 40 102 Patients With First-Ever Ischemic Stroke

(2010) Klaus Kaae Andersen et al.   STROKE

Changes in Experimental Stroke Outcome across the Life Span

(2009) Fudong Liu et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

The HDAC inhibitor, sodium butyrate, stimulates neurogenesis in the ischemic brain

(2009) Hyeon Ju Kim et al.   JOURNAL OF NEUROCHEMISTRY

Pivotal role of cerebral interleukin-17–producing γδT cells in the delayed phase of ischemic brain injury

(2009) Takashi Shichita et al.   NATURE MEDICINE

Multiple roles of HDAC inhibition in neurodegenerative conditions

(2009) De-Maw Chuang et al.   TRENDS IN NEUROSCIENCES

Epigenetic targets of HDAC inhibition in neurodegenerative and psychiatric disorders

(2008) T ABEL et al.   CURRENT OPINION IN PHARMACOLOGY

Sex differences in stroke: epidemiology, clinical presentation, medical care, and outcomes

(2008) Mathew J Reeves et al.   LANCET NEUROLOGY

Reproductive age modulates the impact of focal ischemia on the forebrain as well as the effects of estrogen treatment in female rats

(2008) Amutha Selvamani et al.   NEUROBIOLOGY OF AGING

Effect of experimental stroke on peripheral immunity: CNS ischemia induces profound immunosuppression

(2008) H. Offner et al.   NEUROSCIENCE

Glial Fibrillary Acidic Protein is Highly Correlated With Brain Injury

(2008) Kimberly M. Lumpkins et al.   JOURNAL OF TRAUMA-INJURY INFECTION AND CRITICAL CARE