Unraveling the functional role of the orphan solute carrier, SLC22A24 in the transport of steroid conjugates through metabolomic and genome-wide association studies
Published 2019 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Unraveling the functional role of the orphan solute carrier, SLC22A24 in the transport of steroid conjugates through metabolomic and genome-wide association studies
Authors
Keywords
Steroids, Anions, Kidneys, Sulfates, Metabolomics, Genome-wide association studies, Drug metabolism, Membrane proteins
Journal
PLoS Genetics
Volume 15, Issue 9, Pages e1008208
Publisher
Public Library of Science (PLoS)
Online
2019-09-26
DOI
10.1371/journal.pgen.1008208
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Impact of estrogens in males and androgens in females
- (2019) Stephen R. Hammes et al. JOURNAL OF CLINICAL INVESTIGATION
- Single-Cell Transcriptomics of a Human Kidney Allograft Biopsy Specimen Defines a Diverse Inflammatory Response
- (2018) Haojia Wu et al. JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY
- Structural biology of solute carrier (SLC) membrane transport proteins
- (2018) Xiaoyun Bai et al. MOLECULAR MEMBRANE BIOLOGY
- Molecular Mechanisms for Species Differences in Organic Anion Transporter 1, OAT1: Implications for Renal Drug Toxicity
- (2018) Ling Zou et al. MOLECULAR PHARMACOLOGY
- Whole-exome sequencing identifies common and rare variant metabolic QTLs in a Middle Eastern population
- (2018) Noha A. Yousri et al. Nature Communications
- Steroid Transport, Local Synthesis, and Signaling within the Brain: Roles in Neurogenesis, Neuroprotection, and Sexual Behaviors
- (2018) Nicolas Diotel et al. Frontiers in Neuroscience
- An eQTL Landscape of Kidney Tissue in Human Nephrotic Syndrome
- (2018) Christopher E. Gillies et al. AMERICAN JOURNAL OF HUMAN GENETICS
- Renal compartment–specific genetic variation analyses identify new pathways in chronic kidney disease
- (2018) Chengxiang Qiu et al. NATURE MEDICINE
- Bile Acid Synthesis: From Nature to the Chemical Modification and Synthesis and Their Applications as Drugs and Nutrients
- (2018) Tanja M. Šarenac et al. Frontiers in Pharmacology
- Comparative Analysis and Refinement of Human PSC-Derived Kidney Organoid Differentiation with Single-Cell Transcriptomics
- (2018) Haojia Wu et al. Cell Stem Cell
- Combination Metabolomics Approach for Identifying Endogenous Substrates of Carnitine/Organic Cation Transporter OCTN1
- (2018) Yusuke Masuo et al. PHARMACEUTICAL RESEARCH
- Neutrophils life under estrogenic and xenoestrogenic control
- (2018) Karolina Nowak et al. JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY
- Computational Discovery and Experimental Validation of Inhibitors of the Human Intestinal Transporter OATP2B1
- (2017) Natalia Khuri et al. Journal of Chemical Information and Modeling
- Discovery of Competitive and Noncompetitive Ligands of the Organic Cation Transporter 1 (OCT1; SLC22A1)
- (2017) Eugene C. Chen et al. JOURNAL OF MEDICINAL CHEMISTRY
- Functional selectivity of GPCR-directed drug action through location bias
- (2017) Roshanak Irannejad et al. Nature Chemical Biology
- Whole-genome sequencing identifies common-to-rare variants associated with human blood metabolites
- (2017) Tao Long et al. NATURE GENETICS
- Ensembl 2018
- (2017) Daniel R Zerbino et al. NUCLEIC ACIDS RESEARCH
- Improvements to the APBS biomolecular solvation software suite
- (2017) Elizabeth Jurrus et al. PROTEIN SCIENCE
- Classification Systems of Secondary Active Transporters
- (2017) Emelie Perland et al. TRENDS IN PHARMACOLOGICAL SCIENCES
- Associations Between the Serum Metabolome and All-Cause Mortality Among African Americans in the Atherosclerosis Risk in Communities (ARIC) Study
- (2016) Bing Yu et al. AMERICAN JOURNAL OF EPIDEMIOLOGY
- Metabolomic and Genome-wide Association Studies Reveal Potential Endogenous Biomarkers for OATP1B1
- (2016) SW Yee et al. CLINICAL PHARMACOLOGY & THERAPEUTICS
- The α-Arrestin ARRDC3 Regulates the Endosomal Residence Time and Intracellular Signaling of the β2-Adrenergic Receptor
- (2016) Xufan Tian et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Transcriptomics resources of human tissues and organs
- (2016) M. Uhlen et al. Molecular Systems Biology
- Chimpanzee genomic diversity reveals ancient admixture with bonobos
- (2016) M. de Manuel et al. SCIENCE
- Loss-of-function variants influence the human serum metabolome
- (2016) B. Yu et al. Science Advances
- A Call for Systematic Research on Solute Carriers
- (2015) Adrián César-Razquin et al. CELL
- Genome-wide association study with 1000 genomes imputation identifies signals for nine sex hormone-related phenotypes
- (2015) Katherine S Ruth et al. EUROPEAN JOURNAL OF HUMAN GENETICS
- Rapid Comparison of Metabolites in Humans and Rats of Different Sexes Using Untargeted Ultraperformance Liquid Chromatography Coupled to Time-of-Flight Mass Spectrometry and an in-house Software Platform
- (2015) Qiande Liang et al. EUROPEAN JOURNAL OF MASS SPECTROMETRY
- Molecular basis of ligand recognition and transport by glucose transporters
- (2015) Dong Deng et al. NATURE
- An integrated map of structural variation in 2,504 human genomes
- (2015) Peter H. Sudmant et al. NATURE
- SLC transporters as therapeutic targets: emerging opportunities
- (2015) Lawrence Lin et al. NATURE REVIEWS DRUG DISCOVERY
- The Organic Anion Transporter (OAT) Family: A Systems Biology Perspective
- (2015) Sanjay K. Nigam et al. PHYSIOLOGICAL REVIEWS
- Evolutionary Analysis and Classification of OATs, OCTs, OCTNs, and Other SLC22 Transporters: Structure-Function Implications and Analysis of Sequence Motifs
- (2015) Christopher Zhu et al. PLoS One
- RAxML version 8: a tool for phylogenetic analysis and post-analysis of large phylogenies
- (2014) Alexandros Stamatakis BIOINFORMATICS
- An atlas of genetic influences on human blood metabolites
- (2014) So-Youn Shin et al. NATURE GENETICS
- Genome-Wide Association Study of Maternal and Inherited Loci for Conotruncal Heart Defects
- (2014) A. J. Agopian et al. PLoS One
- OCT1 is a high-capacity thiamine transporter that regulates hepatic steatosis and is a target of metformin
- (2014) Ligong Chen et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Genetic Determinants Influencing Human Serum Metabolome among African Americans
- (2014) Bing Yu et al. PLoS Genetics
- Testosterone administration inhibits hepcidin transcription and is associated with increased iron incorporation into red blood cells
- (2013) Wen Guo et al. AGING CELL
- The National Institutes of Health Neurobiobank: A Federated National Network of Human Brain and Tissue Repositories
- (2013) Lisa Nichols et al. BIOLOGICAL PSYCHIATRY
- Genome-wide association study of sex hormones, gonadotropins and sex hormone–binding protein in Chinese men
- (2013) Zhuo Chen et al. JOURNAL OF MEDICAL GENETICS
- Reduced Renal Clearance of Cefotaxime in Asians with a Low-Frequency Polymorphism of OAT3 (SLC22A8)
- (2013) Sook Wah Yee et al. JOURNAL OF PHARMACEUTICAL SCIENCES
- Testosterone Induces Erythrocytosis via Increased Erythropoietin and Suppressed Hepcidin: Evidence for a New Erythropoietin/Hemoglobin Set Point
- (2013) E. Bachman et al. JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES
- The SLC22 family with transporters of organic cations, anions and zwitterions
- (2013) Hermann Koepsell MOLECULAR ASPECTS OF MEDICINE
- The ABCs of membrane transporters in health and disease (SLC series): Introduction
- (2013) Matthias A. Hediger et al. MOLECULAR ASPECTS OF MEDICINE
- Conformational biosensors reveal GPCR signalling from endosomes
- (2013) Roshanak Irannejad et al. NATURE
- Genome-wide association study identifies a new locus JMJD1C at 10q21 that may influence serum androgen levels in men
- (2012) Guangfu Jin et al. HUMAN MOLECULAR GENETICS
- Genome-Wide Association Study of Circulating Estradiol, Testosterone, and Sex Hormone-Binding Globulin in Postmenopausal Women
- (2012) Jennifer Prescott et al. PLoS One
- A High-Coverage Genome Sequence from an Archaic Denisovan Individual
- (2012) M. Meyer et al. SCIENCE
- Dendroscope 3: An Interactive Tool for Rooted Phylogenetic Trees and Networks
- (2012) Daniel H. Huson et al. SYSTEMATIC BIOLOGY
- A Genome-Wide Association Meta-Analysis of Circulating Sex Hormone–Binding Globulin Reveals Multiple Loci Implicated in Sex Steroid Hormone Regulation
- (2012) Andrea D. Coviello et al. PLoS Genetics
- The Molecular Biology, Biochemistry, and Physiology of Human Steroidogenesis and Its Disorders
- (2011) Walter L. Miller et al. ENDOCRINE REVIEWS
- Protein Significance Analysis in Selected Reaction Monitoring (SRM) Measurements
- (2011) Ching-Yun Chang et al. MOLECULAR & CELLULAR PROTEOMICS
- Human metabolic individuality in biomedical and pharmaceutical research
- (2011) Karsten Suhre et al. NATURE
- Genetic Determinants of Serum Testosterone Concentrations in Men
- (2011) Claes Ohlsson et al. PLoS Genetics
- Identification of a Novel Organic Anion Transporter Mediating Carnitine Transport in Mouse Liver and Kidney
- (2010) Hiroki Tsuchida et al. CELLULAR PHYSIOLOGY AND BIOCHEMISTRY
- Membrane transporters in drug development
- (2010) NATURE REVIEWS DRUG DISCOVERY
- A Draft Sequence of the Neandertal Genome
- (2010) R. E. Green et al. SCIENCE
- Organization of GC/MS and LC/MS metabolomics data into chemical libraries
- (2010) Corey D DeHaven et al. Journal of Cheminformatics
- Universal sample preparation method for proteome analysis
- (2009) Jacek R Wiśniewski et al. NATURE METHODS
- Analysis of a large cluster of SLC22 transporter genes, including novel USTs, reveals species-specific amplification of subsets of family members
- (2009) Wei Wu et al. PHYSIOLOGICAL GENOMICS
- Functional and Immunochemical Characterization of a Novel Organic Anion Transporter Oat8 (Slc22a9) in Rat Renal Collecting Duct
- (2008) Hirokazu Yokoyama et al. CELLULAR PHYSIOLOGY AND BIOCHEMISTRY
- Isolation and quantification by high-performance liquid chromatography–ion-trap mass spectrometry of androgen sulfoconjugates in human urine
- (2008) Emmanuel Strahm et al. JOURNAL OF CHROMATOGRAPHY A
- Organic Anion Transporter 2 (SLC22A7) Is a Facilitative Transporter of cGMP
- (2008) C. D. Cropp et al. MOLECULAR PHARMACOLOGY
- SLC2A9 is a newly identified urate transporter influencing serum urate concentration, urate excretion and gout
- (2008) Veronique Vitart et al. NATURE GENETICS
- PROMALS3D: a tool for multiple protein sequence and structure alignments
- (2008) Jimin Pei et al. NUCLEIC ACIDS RESEARCH
Discover Peeref hubs
Discuss science. Find collaborators. Network.
Join a conversationCreate your own webinar
Interested in hosting your own webinar? Check the schedule and propose your idea to the Peeref Content Team.
Create Now