Functional selectivity of GPCR-directed drug action through location bias

G protein βγ subunits regulate cardiomyocyte hypertrophy through a perinuclear Golgi phosphatidylinositol 4-phosphate hydrolysis pathway

(2015) S. Malik et al.   MOLECULAR BIOLOGY OF THE CELL

Probing the pharmacology of G protein-coupled receptors with fluorescent ligands

(2015) Leigh A. Stoddart et al.   NEUROPHARMACOLOGY

Control Systems of Membrane Transport at the Interface between the Endoplasmic Reticulum and the Golgi

(2014) Jorge Cancino et al.   DEVELOPMENTAL CELL

Endophilin marks and controls a clathrin-independent endocytic pathway

(2014) Emmanuel Boucrot et al.   NATURE

Spatial encoding of cyclic AMP signaling specificity by GPCR endocytosis

(2014) Nikoleta G Tsvetanova et al.   Nature Chemical Biology

Gαs regulates the post-endocytic sorting of G protein-coupled receptors

(2014) Stéphanie Rosciglione et al.   Nature Communications

Phospholipase Cε Hydrolyzes Perinuclear Phosphatidylinositol 4-Phosphate to Regulate Cardiac Hypertrophy

(2013) Lianghui Zhang et al.   CELL

Conformational biosensors reveal GPCR signalling from endosomes

(2013) Roshanak Irannejad et al.   NATURE

The ESCRT machinery mediates polarization of fibroblasts through regulation of myosin light chain

(2012) V. H. Lobert et al.   JOURNAL OF CELL SCIENCE

OATPs, OATs and OCTs: the organic anion and cation transporters of the SLCO and SLC22A gene superfamilies

(2011) Megan Roth et al.   BRITISH JOURNAL OF PHARMACOLOGY

Isoproterenol Cytotoxicity is Dependent on the Differentiation State of the Cardiomyoblast H9c2 Cell Line

(2011) Ana F. Branco et al.   Cardiovascular Toxicology

Nanobody stabilization of G protein-coupled receptor conformational states

(2011) Jan Steyaert et al.   CURRENT OPINION IN STRUCTURAL BIOLOGY

Structure of a nanobody-stabilized active state of the β2 adrenoceptor

(2011) Søren G. F. Rasmussen et al.   NATURE

Structural flexibility of the G s  -helical domain in the  2-adrenoceptor Gs complex

(2011) G. H. Westfield et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Regulation of Constitutive Cargo Transport from thetrans-Golgi Network to Plasma Membrane by Golgi-localized G Protein βγ Subunits

(2010) Roshanak Irannejad et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

 2-Adrenergic Receptor Redistribution in Heart Failure Changes cAMP Compartmentation

(2010) V. O. Nikolaev et al.   SCIENCE

Sustained cyclic AMP production by parathyroid hormone receptor endocytosis

(2009) Sébastien Ferrandon et al.   Nature Chemical Biology

Persistent signaling induced by FTY720-phosphate is mediated by internalized S1P1 receptors

(2009) Florian Mullershausen et al.   Nature Chemical Biology

PKA-Mediated Golgi Remodeling During cAMP Signal Transmission

(2009) Fabiola Mavillard et al.   TRAFFIC

Persistent cAMP-Signals Triggered by Internalized G-Protein–Coupled Receptors

(2009) Davide Calebiro et al.   PLOS BIOLOGY

Nuclear α1-Adrenergic Receptors Signal Activated ERK Localization to Caveolae in Adult Cardiac Myocytes

(2008) Casey D. Wright et al.   CIRCULATION RESEARCH

Adenosine A2A receptor dynamics studied with the novel fluorescent agonist Alexa488-APEC

(2008) Frank Brand et al.   EUROPEAN JOURNAL OF PHARMACOLOGY