Metabolomic and Genome-wide Association Studies Reveal Potential Endogenous Biomarkers for OATP1B1

Comparing Various In Vitro Prediction Criteria to Assess the Potential of a New Molecular Entity to Inhibit Organic Anion Transporting Polypeptide 1B1

(2016) Jayabharathi Vaidyanathan et al.   JOURNAL OF CLINICAL PHARMACOLOGY

The Effect of Famotidine, a MATE1-Selective Inhibitor, on the Pharmacokinetics and Pharmacodynamics of Metformin

(2015) Jennifer E. Hibma et al.   CLINICAL PHARMACOKINETICS

The Effect of Nizatidine, a MATE2K Selective Inhibitor, on the Pharmacokinetics and Pharmacodynamics of Metformin in Healthy Volunteers

(2015) Kari M. Morrissey et al.   CLINICAL PHARMACOKINETICS

Interplay of Drug-Metabolizing Enzymes and Transporters in Drug Absorption and Disposition

(2015) Shaojun Shi et al.   CURRENT DRUG METABOLISM

Flagging Drugs That Inhibit the Bile Salt Export Pump

(2015) Floriane Montanari et al.   MOLECULAR PHARMACEUTICS

The Organic Anion Transporter (OAT) Family: A Systems Biology Perspective

(2015) Sanjay K. Nigam et al.   PHYSIOLOGICAL REVIEWS

Novel genetic associations with serum level metabolites identified by phenotype set enrichment analyses

(2014) Janina S. Ried et al.   HUMAN MOLECULAR GENETICS

Contribution of the organic anion transporter OAT2 to the renal active tubular secretion of creatinine and mechanism for serum creatinine elevations caused by cobicistat

(2014) Eve-Irene Lepist et al.   KIDNEY INTERNATIONAL

An atlas of genetic influences on human blood metabolites

(2014) So-Youn Shin et al.   NATURE GENETICS

OCT1 is a high-capacity thiamine transporter that regulates hepatic steatosis and is a target of metformin

(2014) Ligong Chen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A Genome-wide Association Study of the Human Metabolome in a Community-Based Cohort

(2013) Eugene P. Rhee et al.   Cell Metabolism

Reduced Renal Clearance of Cefotaxime in Asians with a Low-Frequency Polymorphism of OAT3 (SLC22A8)

(2013) Sook Wah Yee et al.   JOURNAL OF PHARMACEUTICAL SCIENCES

The SLCO (former SLC21) superfamily of transporters

(2013) Bruno Hagenbuch et al.   MOLECULAR ASPECTS OF MEDICINE

Investigation of Endogenous Compounds for Assessing the Drug Interactions in the Urinary Excretion Involving Multidrug and Toxin Extrusion Proteins

(2013) Koji Kato et al.   PHARMACEUTICAL RESEARCH

OATP1B1-related drug–drug and drug–gene interactions as potential risk factors for cerivastatin-induced rhabdomyolysis

(2013) Bani Tamraz et al.   Pharmacogenetics and Genomics

Conditional knockout of the Slc5a6 gene in mouse intestine impairs biotin absorption

(2012) Abhisek Ghosal et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

N-Methylnicotinamide Is an Endogenous Probe for Evaluation of Drug–Drug Interactions Involving Multidrug and Toxin Extrusions (MATE1 and MATE2-K)

(2012) S Ito et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

The UCSF-FDA TransPortal: A Public Drug Transporter Database

(2012) K M Morrissey et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

Gene Expression Profiling of Transporters in the Solute Carrier and ATP-Binding Cassette Superfamilies in Human Eye Substructures

(2012) Amber Dahlin et al.   MOLECULAR PHARMACEUTICS

Genome-wide association study identifies multiple loci influencing human serum metabolite levels

(2012) Johannes Kettunen et al.   NATURE GENETICS

Expression and function of renal and hepatic organic anion transporters in extrahepatic cholestasis

(2012) Anabel Brandoni   WORLD JOURNAL OF GASTROENTEROLOGY

Detailed metabolic and genetic characterization reveals new associations for 30 known lipid loci

(2011) T. Tukiainen et al.   HUMAN MOLECULAR GENETICS

Human metabolic individuality in biomedical and pharmaceutical research

(2011) Karsten Suhre et al.   NATURE

Organic Anion Transporting Polypeptide 1B1: a Genetically Polymorphic Transporter of Major Importance for Hepatic Drug Uptake

(2011) M. Niemi et al.   PHARMACOLOGICAL REVIEWS

Transporter Studies with the 3-O-Sulfate Conjugate of 17 -Ethinylestradiol: Assessment of Human Kidney Drug Transporters

(2010) Y.-H. Han et al.   DRUG METABOLISM AND DISPOSITION

Fatty acid omega-oxidation as a rescue pathway for fatty acid oxidation disorders in humans

(2010) Ronald J. A. Wanders et al.   FEBS Journal

Membrane transporters in drug development

(2010)   NATURE REVIEWS DRUG DISCOVERY

The Role of Organic Anion–Transporting Polypeptides and Their Common Genetic Variants in Mycophenolic Acid Pharmacokinetics

(2009) N Picard et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

Genome-wide association meta-analysis for total serum bilirubin levels

(2009) A. D. Johnson et al.   HUMAN MOLECULAR GENETICS

Common variants in the SLCO1B3 locus are associated with bilirubin levels and unconjugated hyperbilirubinemia

(2009) Serena Sanna et al.   HUMAN MOLECULAR GENETICS

Effect of SLCO1B1 polymorphism on the plasma concentrations of bile acids and bile acid synthesis marker in humans

(2009) Xiaoqiang Xiang et al.   Pharmacogenetics and Genomics

The Inhibition of Human Multidrug and Toxin Extrusion 1 Is Involved in the Drug-Drug Interaction Caused by Cimetidine

(2008) S. Matsushima et al.   DRUG METABOLISM AND DISPOSITION

SLC2A9 is a newly identified urate transporter influencing serum urate concentration, urate excretion and gout

(2008) Veronique Vitart et al.   NATURE GENETICS