Evolutionary Analysis and Classification of OATs, OCTs, OCTNs, and Other SLC22 Transporters: Structure-Function Implications and Analysis of Sequence Motifs

A Call for Systematic Research on Solute Carriers

(2015) Adrián César-Razquin et al.   CELL

The EMBL-EBI bioinformatics web and programmatic tools framework

(2015) Weizhong Li et al.   NUCLEIC ACIDS RESEARCH

The Organic Anion Transporter (OAT) Family: A Systems Biology Perspective

(2015) Sanjay K. Nigam et al.   PHYSIOLOGICAL REVIEWS

In vitro and in vivo radiosensitization of human glioma U251 cells induced by upregulated expression of SLC22A18

(2014) S-H Chu et al.   CANCER GENE THERAPY

What do drug transporters really do?

(2014) Sanjay K. Nigam   NATURE REVIEWS DRUG DISCOVERY

The SLC22 family with transporters of organic cations, anions and zwitterions

(2013) Hermann Koepsell   MOLECULAR ASPECTS OF MEDICINE

The Transporter Classification Database

(2013) Milton H. Saier et al.   NUCLEIC ACIDS RESEARCH

BLAST: a more efficient report with usability improvements

(2013) Grzegorz M. Boratyn et al.   NUCLEIC ACIDS RESEARCH

Organic anion transport pathways in antiviral handling in choroid plexus in Oat1 (Slc22a6) and Oat3 (Slc22a8) deficient tissue

(2012) Megha A. Nagle et al.   NEUROSCIENCE LETTERS

Drug transport by Organic Anion Transporters (OATs)

(2012) Gerhard Burckhardt   PHARMACOLOGY & THERAPEUTICS

Conformational Changes of the Multispecific Transporter Organic Anion Transporter 1 (OAT1/SLC22A6) Suggests a Molecular Mechanism for Initial Stages of Drug and Metabolite Transport

(2011) Igor F. Tsigelny et al.   CELL BIOCHEMISTRY AND BIOPHYSICS

The Large Extracellular Loop of Organic Cation Transporter 1 Influences Substrate Affinity and Is Pivotal for Oligomerization

(2011) Thorsten Keller et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Expression and analysis of two novel rat organic cation transporter homologs, SLC22A17 and SLC22A23

(2011) Katie M. Bennett et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

Remote Communication through Solute Carriers and ATP Binding Cassette Drug Transporter Pathways: An Update on the Remote Sensing and Signaling Hypothesis

(2011) W. Wu et al.   MOLECULAR PHARMACOLOGY

Getting Started in Gene Orthology and Functional Analysis

(2010) Gang Fang et al.   PLoS Computational Biology

Interaction of Organic Cations with Organic Anion Transporters

(2009) Sun-Young Ahn et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Toward a Systems Level Understanding of Organic Anion and Other Multispecific Drug Transporters: A Remote Sensing and Signaling Hypothesis

(2009) S.-Y. Ahn et al.   MOLECULAR PHARMACOLOGY

Analysis of a large cluster of SLC22 transporter genes, including novel USTs, reveals species-specific amplification of subsets of family members

(2009) Wei Wu et al.   PHYSIOLOGICAL GENOMICS

Independent elaboration of steroid hormone signaling pathways in metazoans

(2009) G. V. Markov et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Identification of a New Urate and High Affinity Nicotinate Transporter, hOAT10 (SLC22A13)

(2008) Andrew Bahn et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Physiology, structure, and regulation of the cloned organic anion transporters

(2008) C. Srimaroeng et al.   XENOBIOTICA