Drug Nanorod-Mediated Intracellular Delivery of microRNA-101 for Self-sensitization via Autophagy Inhibition

Nanoplatform Assembled from a CD44-Targeted Prodrug and Smart Liposomes for Dual Targeting of Tumor Microenvironment and Cancer Cells

(2018) Yaqi Lv et al.   ACS Nano

Protein delivery into cells using inorganic nanoparticle–protein supramolecular assemblies

(2018) Federica Scaletti et al.   CHEMICAL SOCIETY REVIEWS

Autophagy Inhibition Mediates Apoptosis Sensitization in Cancer Therapy by Relieving FOXO3a Turnover

(2018) Brent E. Fitzwalter et al.   DEVELOPMENTAL CELL

A drug-delivering-drug strategy for combined treatment of metastatic breast cancer

(2018) Qingqing Xiao et al.   Nanomedicine-Nanotechnology Biology and Medicine

A Smart Paclitaxel-Disulfiram Nanococrystals for Efficient MDR Reversal and Enhanced Apoptosis

(2018) Imran Shair Mohammad et al.   PHARMACEUTICAL RESEARCH

PU.1/microRNA-142-3p targets ATG5/ATG16L1 to inactivate autophagy and sensitize hepatocellular carcinoma cells to sorafenib

(2018) Kai Zhang et al.   Cell Death & Disease

Physical characterization and in vivo organ distribution of coated iron oxide nanoparticles

(2018) Anirudh Sharma et al.   Scientific Reports

Drug-delivering-drug platform-mediated potent protein therapeutics via a non-endo-lysosomal route

(2018) Xiaofei Xin et al.   Theranostics

Reassessment of long circulation via monitoring of integral polymeric nanoparticles justifies a more accurate understanding

(2018) Haisheng He et al.   Nanoscale Horizons

Necrotic, apoptotic and autophagic cell fates triggered by nanoparticles

(2018) Reza Mohammadinejad et al.   Autophagy

Overcoming drug-resistant lung cancer by paclitaxel loaded tetrahedral DNA nanostructures

(2018) X. Xie et al.   Nanoscale

Drug-delivering-drug approach-based codelivery of paclitaxel and disulfiram for treating multidrug-resistant cancer

(2018) Imran Shair Mohammad et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

A drug-delivery strategy for overcoming drug resistance in breast cancer through targeting of oncofetal fibronectin

(2017) Phei Er Saw et al.   Nanomedicine-Nanotechnology Biology and Medicine

Synergistic drug combinations for cancer identified in a CRISPR screen for pairwise genetic interactions

(2017) Kyuho Han et al.   NATURE BIOTECHNOLOGY

Cell-permeable nanobodies for targeted immunolabelling and antigen manipulation in living cells

(2017) Henry D. Herce et al.   Nature Chemistry

Pharmacological modulation of autophagy: therapeutic potential and persisting obstacles

(2017) Lorenzo Galluzzi et al.   NATURE REVIEWS DRUG DISCOVERY

Rod-Shaped Drug Particles for Cancer Therapy: The Importance of Particle Size and Participation of Caveolae Pathway

(2017) Wei He et al.   PARTICLE & PARTICLE SYSTEMS CHARACTERIZATION

Rod-Shaped Active Drug Particles Enable Efficient and Safe Gene Delivery

(2017) Xiaofei Xin et al.   Advanced Science

Co-delivery of chemotherapeutics and proteins for synergistic therapy

(2016) Chaoliang He et al.   ADVANCED DRUG DELIVERY REVIEWS

In vitro and ex vivo strategies for intracellular delivery

(2016) Martin P. Stewart et al.   NATURE

Materials and methods for delivery of biological drugs

(2016) Alexander N. Zelikin et al.   Nature Chemistry

Combine and conquer: challenges for targeted therapy combinations in early phase trials

(2016) Juanita S. Lopez et al.   Nature Reviews Clinical Oncology

Autophagy in cancer metastasis

(2016) E E Mowers et al.   ONCOGENE

Autophagy inhibition re-sensitizes pulse stimulation-selected paclitaxel-resistant triple negative breast cancer cells to chemotherapy-induced apoptosis

(2015) Jian Wen et al.   BREAST CANCER RESEARCH AND TREATMENT

Pharmacologic agents targeting autophagy

(2015) Helin Vakifahmetoglu-Norberg et al.   JOURNAL OF CLINICAL INVESTIGATION

Environment-responsive aza-BODIPY dyes quenching in water as potential probes to visualize the in vivo fate of lipid-based nanocarriers

(2015) Xiongwei Hu et al.   Nanomedicine-Nanotechnology Biology and Medicine

Cleaved CD44 intracellular domain supports activation of stemness factors and promotes tumorigenesis of breast cancer

(2015) Yunhee Cho et al.   Oncotarget

The chemotherapeutic potential of PEG-b-PLGA copolymer micelles that combine chloroquine as autophagy inhibitor and docetaxel as an anti-cancer drug

(2014) Xudong Zhang et al.   BIOMATERIALS

Exploiting Intrinsic Nanoparticle Toxicity: The Pros and Cons of Nanoparticle-Induced Autophagy in Biomedical Research

(2014) Karen Peynshaert et al.   CHEMICAL REVIEWS

Enhancing Therapeutic Effects of Docetaxel-Loaded Dendritic Copolymer Nanoparticles by Co-Treatment with Autophagy Inhibitor on Breast Cancer

(2014) Xudong Zhang et al.   Theranostics

The effect of autophagy inhibitors on drug delivery using biodegradable polymer nanoparticles in cancer treatment

(2013) Xudong Zhang et al.   BIOMATERIALS

Image-based analysis of lipid nanoparticle–mediated siRNA delivery, intracellular trafficking and endosomal escape

(2013) Jerome Gilleron et al.   NATURE BIOTECHNOLOGY

miR-101 inhibits autophagy and enhances cisplatin-induced apoptosis in hepatocellular carcinoma cells

(2013) YONGHUA XU et al.   ONCOLOGY REPORTS

Monitoring autophagic flux by an improved tandem fluorescent-tagged LC3 (mTagRFP-mWasabi-LC3) reveals that high-dose rapamycin impairs autophagic flux in cancer cells

(2012) Cuihong Zhou et al.   Autophagy

MicroRNA regulation of autophagy

(2012) L. B. Frankel et al.   CARCINOGENESIS

Sequential Application of Anticancer Drugs Enhances Cell Death by Rewiring Apoptotic Signaling Networks

(2012) Michael J. Lee et al.   CELL

Combinatorial drug therapy for cancer in the post-genomic era

(2012) Bissan Al-Lazikani et al.   NATURE BIOTECHNOLOGY

Combination delivery of TGF-β inhibitor and IL-2 by nanoscale liposomal polymeric gels enhances tumour immunotherapy

(2012) Jason Park et al.   NATURE MATERIALS

Anti-Invasive Adjuvant Therapy with Imipramine Blue Enhances Chemotherapeutic Efficacy Against Glioma

(2012) J. M. Munson et al.   Science Translational Medicine

microRNA-101 is a potent inhibitor of autophagy

(2011) Lisa B Frankel et al.   EMBO JOURNAL

Synergistic drug combinations tend to improve therapeutically relevant selectivity

(2009) Joseph Lehár et al.   NATURE BIOTECHNOLOGY

Paclitaxel-Initiated, Controlled Polymerization of Lactide for the Formulation of Polymeric Nanoparticulate Delivery Vehicles

(2008) Rong Tong et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

A genome-wide expression analysis identifies a network of EpCAM-induced cell cycle regulators

(2008) K Maaser et al.   BRITISH JOURNAL OF CANCER