MicroRNA regulation of autophagy

The end of autophagic cell death?

(2012) Shensi Shen et al.   Autophagy

miR-376b controls starvation and mTOR inhibition-related autophagy by targeting ATG4C and BECN1

(2012) Gozde Korkmaz et al.   Autophagy

VHL-Regulated MiR-204 Suppresses Tumor Growth through Inhibition of LC3B-Mediated Autophagy in Renal Clear Cell Carcinoma

(2012) Olga Mikhaylova et al.   CANCER CELL

miRNA-130a Targets ATG2B and DICER1 to Inhibit Autophagy and Trigger Killing of Chronic Lymphocytic Leukemia Cells

(2012) V. Kovaleva et al.   CANCER RESEARCH

Phospho-ΔNp63α-dependent regulation of autophagic signaling through transcription and micro-RNA modulation

(2012) Yiping Huang et al.   CELL CYCLE

Mammalian Atg2 proteins are essential for autophagosome formation and important for regulation of size and distribution of lipid droplets

(2012) Anoop Kumar G. Velikkakath et al.   MOLECULAR BIOLOGY OF THE CELL

The microcosmos of cancer

(2012) Amaia Lujambio et al.   NATURE

Function and Molecular Mechanism of Acetylation in Autophagy Regulation

(2012) C. Yi et al.   SCIENCE

Atg16L2, a novel isoform of mammalian Atg16L that is not essential for canonical autophagy despite forming an Atg12–5-16L2 complex

(2011) Koutaro Ishibashi et al.   Autophagy

Systems biology of the autophagy-lysosomal pathway

(2011) Anil G. Jegga et al.   Autophagy

MiR-17/20/93/106 promote hematopoietic cell expansion by targeting sequestosome 1-regulated pathways in mice

(2011) A. Meenhuis et al.   BLOOD

Phospho-ΔNp63α/miR-885-3p axis in tumor cell life and cell death upon cisplatin exposure

(2011) Yiping Huang et al.   CELL CYCLE

microRNA-101 is a potent inhibitor of autophagy

(2011) Lisa B Frankel et al.   EMBO JOURNAL

Pancreatic cancers require autophagy for tumor growth

(2011) S. Yang et al.   GENES & DEVELOPMENT

Activated Ras requires autophagy to maintain oxidative metabolism and tumorigenesis

(2011) J. Y. Guo et al.   GENES & DEVELOPMENT

MicroRNA-30a Sensitizes Tumor Cells to cis-Platinum via Suppressing Beclin 1-mediated Autophagy

(2011) Zhenyou Zou et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Inducing Indigestion: Companies Embrace Autophagy Inhibitors

(2011) K. Garber   JNCI-Journal of the National Cancer Institute

Mechanisms and Consequences of Alternative Polyadenylation

(2011) Dafne Campigli Di Giammartino et al.   MOLECULAR CELL

AMPK and mTOR regulate autophagy through direct phosphorylation of Ulk1

(2011) Joungmok Kim et al.   NATURE CELL BIOLOGY

A synonymous variant in IRGM alters a binding site for miR-196 and causes deregulation of IRGM-dependent xenophagy in Crohn's disease

(2011) Patrick Brest et al.   NATURE GENETICS

New perspectives on osteogenesis imperfecta

(2011) Antonella Forlino et al.   Nature Reviews Endocrinology

TFEB Links Autophagy to Lysosomal Biogenesis

(2011) C. Settembre et al.   SCIENCE

Acetylated microtubules are required for fusion of autophagosomes with lysosomes

(2010) Rui Xie et al.   BMC CELL BIOLOGY

MicroRNA-375 Is Downregulated in Gastric Carcinomas and Regulates Cell Survival by Targeting PDK1 and 14-3-3 

(2010) Y. Tsukamoto et al.   CANCER RESEARCH

Methods in Mammalian Autophagy Research

(2010) Noboru Mizushima et al.   CELL

The Beclin 1 interactome

(2010) Congcong He et al.   CURRENT OPINION IN CELL BIOLOGY

Dicer is required for survival of differentiating neural crest cells

(2010) Ahmet Zehir et al.   DEVELOPMENTAL BIOLOGY

Genetic ablation of Dicer in adult forebrain neurons results in abnormal tau hyperphosphorylation and neurodegeneration

(2010) Sébastien S. Hébert et al.   HUMAN MOLECULAR GENETICS

Kinetics Comparisons of Mammalian Atg4 Homologues Indicate Selective Preferences toward Diverse Atg8 Substrates

(2010) Min Li et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Autophagy is essential for mouse sense of balance

(2010) Guillermo Mariño et al.   JOURNAL OF CLINICAL INVESTIGATION

Autophagy facilitates glycolysis during Ras-mediated oncogenic transformation

(2010) Rebecca Lock et al.   MOLECULAR BIOLOGY OF THE CELL

MicroRNA Functions in Stress Responses

(2010) Anthony K.L. Leung et al.   MOLECULAR CELL

Autophagy and the Integrated Stress Response

(2010) Guido Kroemer et al.   MOLECULAR CELL

Network organization of the human autophagy system

(2010) Christian Behrends et al.   NATURE

Human IRGM regulates autophagy and cell-autonomous immunity functions through mitochondria

(2010) Sudha B. Singh et al.   NATURE CELL BIOLOGY

Eaten alive: a history of macroautophagy

(2010) Zhifen Yang et al.   NATURE CELL BIOLOGY

Targeting DNA-PKcs and ATM with miR-101 Sensitizes Tumors to Radiation

(2010) Dan Yan et al.   PLoS One

Genome-wide analysis reveals mechanisms modulating autophagy in normal brain aging and in Alzheimer's disease

(2010) M. M. Lipinski et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Regulation Mechanisms and Signaling Pathways of Autophagy

(2009) Congcong He et al.   Annual Review of Genetics

Atg101, a novel mammalian autophagy protein interacting with Atg13

(2009) Nao Hosokawa et al.   Autophagy

TI-VAMP/VAMP7 and VAMP3/cellubrevin: two v-SNARE proteins involved in specific steps of the autophagy/multivesicular body pathways

(2009) Claudio Marcelo Fader et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

MicroRNA-101, Down-regulated in Hepatocellular Carcinoma, Promotes Apoptosis and Suppresses Tumorigenicity

(2009) H. Su et al.   CANCER RESEARCH

Therapeutic microRNA Delivery Suppresses Tumorigenesis in a Murine Liver Cancer Model

(2009) Janaiah Kota et al.   CELL

MicroRNAs: Target Recognition and Regulatory Functions

(2009) David P. Bartel   CELL

The late stages of autophagy: how does the end begin?

(2009) T Noda et al.   CELL DEATH AND DIFFERENTIATION

p53-independent upregulation of miR-34a during oncogene-induced senescence represses MYC

(2009) N R Christoffersen et al.   CELL DEATH AND DIFFERENTIATION

The Double-Edged Sword of Autophagy Modulation in Cancer

(2009) E. White et al.   CLINICAL CANCER RESEARCH

Mammalian autophagy: core molecular machinery and signaling regulation

(2009) Zhifen Yang et al.   CURRENT OPINION IN CELL BIOLOGY

Dicer1 functions as a haploinsufficient tumor suppressor

(2009) M. S. Kumar et al.   GENES & DEVELOPMENT

Nutrient-dependent mTORC1 Association with the ULK1–Atg13–FIP200 Complex Required for Autophagy

(2009) Nao Hosokawa et al.   MOLECULAR BIOLOGY OF THE CELL

ULK-Atg13-FIP200 Complexes Mediate mTOR Signaling to the Autophagy Machinery

(2009) Chang Hwa Jung et al.   MOLECULAR BIOLOGY OF THE CELL

A Role for Ubiquitin in Selective Autophagy

(2009) Vladimir Kirkin et al.   MOLECULAR CELL

Therapeutic Silencing of MicroRNA-122 in Primates with Chronic Hepatitis C Virus Infection

(2009) R. E. Lanford et al.   SCIENCE

Survival of Cancer Cells Is Maintained by EGFR Independent of Its Kinase Activity

(2008) Zhang Weihua et al.   CANCER CELL

Autophagy in the Pathogenesis of Disease

(2008) Beth Levine et al.   CELL

Regulation of Epidermal Growth Factor Receptor Signaling in Human Cancer Cells by MicroRNA-7

(2008) Rebecca J. Webster et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Role of JNK1-dependent Bcl-2 Phosphorylation in Ceramide-induced Macroautophagy

(2008) Sophie Pattingre et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Rab5 modulates aggregation and toxicity of mutant huntingtin through macroautophagy in cell and fly models of Huntington disease

(2008) B. Ravikumar et al.   JOURNAL OF CELL SCIENCE

An Atg4B Mutant Hampers the Lipidation of LC3 Paralogues and Causes Defects in Autophagosome Closure

(2008) Naonobu Fujita et al.   MOLECULAR BIOLOGY OF THE CELL

JNK1-Mediated Phosphorylation of Bcl-2 Regulates Starvation-Induced Autophagy

(2008) Yongjie Wei et al.   MOLECULAR CELL

LNA-mediated microRNA silencing in non-human primates

(2008) Joacim Elmén et al.   NATURE

Autophagy fights disease through cellular self-digestion

(2008) Noboru Mizushima et al.   NATURE

Beclin1-binding UVRAG targets the class C Vps complex to coordinate autophagosome maturation and endocytic trafficking

(2008) Chengyu Liang et al.   NATURE CELL BIOLOGY

The miR-15a–miR-16-1 cluster controls prostate cancer by targeting multiple oncogenic activities

(2008) Désirée Bonci et al.   NATURE MEDICINE

A role for the NAD-dependent deacetylase Sirt1 in the regulation of autophagy

(2008) I. H. Lee et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

miR-34a repression of SIRT1 regulates apoptosis

(2008) M. Yamakuchi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Genomic Loss of microRNA-101 Leads to Overexpression of Histone Methyltransferase EZH2 in Cancer

(2008) S. Varambally et al.   SCIENCE

The Itinerary of Autophagosomes: From Peripheral Formation to Kiss-and-Run Fusion with Lysosomes

(2008) Luca Jahreiss et al.   TRAFFIC