Phytochemicals based chemopreventive and chemotherapeutic strategies and modern technologies to overcome limitations for better clinical applications

Dietary Compounds as Epigenetic Modulating Agents in Cancer

(2019) Ángeles Carlos-Reyes et al.   Frontiers in Genetics

Dietary Phytochemicals Targeting Cancer Stem Cells

(2019) Alena Liskova et al.   MOLECULES

Increased Oxidative Stress Induced by Rubus Bioactive Compounds Induce Apoptotic Cell Death in Human Breast Cancer Cells

(2019) Blassan P. George et al.   Oxidative Medicine and Cellular Longevity

Bioactive Compounds of Strawberry and Blueberry and Their Potential Health Effects Based on Human Intervention Studies: A Brief Overview

(2019) Katharina Miller et al.   Nutrients

Targeting cancer stem cells with dietary phytochemical - Repositioned drug combinations

(2018) Marion M. Chan et al.   CANCER LETTERS

Targeting Cancer Stem Cells for Chemoprevention of Pancreatic Cancer

(2018) Dharmalingam Subramaniam et al.   CURRENT MEDICINAL CHEMISTRY

Hydroxytyrosol: Bioavailability, toxicity, and clinical applications

(2018) María Robles-Almazan et al.   FOOD RESEARCH INTERNATIONAL

The versatile role of curcumin in cancer prevention and treatment: A focus on PI3K/AKT pathway

(2018) Leila Hamzehzadeh et al.   JOURNAL OF CELLULAR PHYSIOLOGY

From chemo-prevention to epigenetic regulation: The role of isothiocyanates in skin cancer prevention

(2018) Melina Mitsiogianni et al.   PHARMACOLOGY & THERAPEUTICS

An immunological perspective for preventing cancer with berries

(2018) Pan Pan et al.   Journal of Berry Research

Pharmacogenomics of Vincristine-Induced Peripheral Neuropathy: Progress Continues

(2018) Barthelemy Diouf et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

Phenolic Compounds Isolated from Olive Oil as Nutraceutical Tools for the Prevention and Management of Cancer and Cardiovascular Diseases

(2018) Patricia Reboredo-Rodríguez et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Melatonin inhibits breast cancer cell invasion through modulating DJ-1/KLF17/ID-1 signaling pathway

(2018) Gamal H. El-Sokkary et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Oxidative DNA Damage Is Prevented by Extracts of Olive Oil, Hydroxytyrosol, and Other Olive Phenolic Compounds in Human Blood Mononuclear Cells and HL60 Cells

(2018) Roberto Fabiani et al.   JOURNAL OF NUTRITION

Cruciferous Vegetables, Isothiocyanates, and Bladder Cancer Prevention

(2018) Besma Abbaoui et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Olive Oil Effects on Colorectal Cancer

(2018) Antonio Borzì et al.   Nutrients

Evolution of Cancer Pharmacological Treatments at the Turn of the Third Millennium

(2018) Luca Falzone et al.   Frontiers in Pharmacology

Oleanolic Acid Alters Multiple Cell Signaling Pathways: Implication in Cancer Prevention and Therapy

(2017) Lovro Žiberna et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

EGCG inhibited bladder cancer SW780 cell proliferation and migration both in vitro and in vivo via down-regulation of NF-κB and MMP-9

(2017) Ke-Wang Luo et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

Cancer Chemoprevention by Resveratrol: The p53 Tumor Suppressor Protein as a Promising Molecular Target

(2017) Danielly Ferraz da Costa et al.   MOLECULES

Fisetin inhibits liver cancer growth in a mouse model: Relation to dopamine receptor

(2017) Xiang-Feng Liu et al.   ONCOLOGY REPORTS

Diet phytochemicals and cutaneous carcinoma chemoprevention: A review

(2017) Siliang Wang et al.   PHARMACOLOGICAL RESEARCH

Regulation of PCSK9 by nutraceuticals

(2017) Amir Abbas Momtazi et al.   PHARMACOLOGICAL RESEARCH

Increased dietary and circulating lycopene are associated with reduced prostate cancer risk: a systematic review and meta-analysis

(2017) J L Rowles et al.   PROSTATE CANCER AND PROSTATIC DISEASES

Anticancer effect of curcumin inhibits cell growth through miR-21/PTEN/Akt pathway in breast cancer cell

(2017) Xinzheng Wang et al.   Oncology Letters

Targeting Colorectal Cancer Proliferation, Stemness and Metastatic Potential Using Brassicaceae Extracts Enriched in Isothiocyanates: A 3D Cell Model-Based Study

(2017) Lucília Pereira et al.   Nutrients

Enhancement of the bioavailability of a novel anticancer compound (acetyltanshinone IIA) by encapsulation within mPEG-PLGA nanoparticles: a study of formulation optimization, toxicity, and pharmacokinetics

(2017) Qi Wang et al.   Oncotarget

Current Multistage Drug Delivery Systems Based on the Tumor Microenvironment

(2017) Binlong Chen et al.   Theranostics

Anticancer Activity of Pterostilbene in Human Ovarian Cancer Cell Lines

(2017) Hui-lin Pei et al.   MEDICAL SCIENCE MONITOR

Phytochemical-induced nucleolar stress results in the inhibition of breast cancer cell proliferation

(2017) Anna Lewinska et al.   Redox Biology

Chemotherapeutic Drugs: DNA Damage and Repair in Glioblastoma

(2017) et al.   Cancers

Apigenin suppresses the senescence-associated secretory phenotype and paracrine effects on breast cancer cells

(2017) Kevin M. Perrott et al.   GeroScience

A novel ECG analog 4-(S)-(2,4,6-trimethylthiobenzyl)-epigallocatechin gallate selectively induces apoptosis of B16-F10 melanoma via activation of autophagy and ROS

(2017) Jing Xie et al.   Scientific Reports

Sulforaphane suppresses in vitro and in vivo lung tumorigenesis through downregulation of HDAC activity

(2016) Li-Li Jiang et al.   BIOMEDICINE & PHARMACOTHERAPY

Inhibition of mTOR by apigenin in UVB-irradiated keratinocytes: A new implication of skin cancer prevention

(2016) Bryan B. Bridgeman et al.   CELLULAR SIGNALLING

Anti-Warburg effect of rosmarinic acid via miR-155 in colorectal carcinoma cells

(2016) Yichun Xu et al.   EUROPEAN JOURNAL OF CANCER PREVENTION

Nanomicelles loaded with doxorubicin and curcumin for alleviating multidrug resistance in lung cancer

(2016) Yue Gu et al.   International Journal of Nanomedicine

Promising Health Benefits of the Strawberry: A Focus on Clinical Studies

(2016) Sadia Afrin et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Rosmarinic acid inhibits inflammation and angiogenesis of hepatocellular carcinoma by suppression of NF-κB signaling in H22 tumor-bearing mice

(2016) Wen Cao et al.   JOURNAL OF PHARMACOLOGICAL SCIENCES

Development and evaluation of topotecan loaded solid lipid nanoparticles: A study in cervical cancer cell lines

(2016) Zhao-jie Chen et al.   JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY B-BIOLOGY

Genistein sensitizes sarcoma cellsin vitroandin vivoby enhancing apoptosis and by inhibiting DSB repair pathways

(2016) X.X. Liu et al.   JOURNAL OF RADIATION RESEARCH

Disease Subtype–Independent Biomarkers of Breast Cancer Chemoprevention by the Ayurvedic Medicine Phytochemical Withaferin A

(2016) Suman K. Samanta et al.   JNCI-Journal of the National Cancer Institute

Potential Pharmacological Resources: Natural Bioactive Compounds from Marine-Derived Fungi

(2016) Liming Jin et al.   Marine Drugs

Capsaicin: From Plants to a Cancer-Suppressing Agent

(2016) Angela Chapa-Oliver et al.   MOLECULES

Docetaxel-Loaded PLGA Nanoparticles Improve Efficacy in Taxane-Resistant Triple-Negative Breast Cancer

(2016) Charles J. Bowerman et al.   NANO LETTERS

Curcumin induced apoptosis via PI3K/Akt-signalling pathways in SKOV3 cells

(2016) Zeshun Yu et al.   PHARMACEUTICAL BIOLOGY

Epigenetic reactivation of RASSF1A by phenethyl isothiocyanate (PEITC) and promotion of apoptosis in LNCaP cells

(2016) Sarandeep S.S. Boyanapalli et al.   PHARMACOLOGICAL RESEARCH

Phytomedicine—Modulating oxidative stress and the tumor microenvironment for cancer therapy

(2016) Yu-Ting Cheng et al.   PHARMACOLOGICAL RESEARCH

Emblica officinalis (Amla): A review for its phytochemistry, ethnomedicinal uses and medicinal potentials with respect to molecular mechanisms

(2016) Bhavesh C. Variya et al.   PHARMACOLOGICAL RESEARCH

6-Gingerol Mediates its Anti Tumor Activities in Human Oral and Cervical Cancer Cell Lines through Apoptosis and Cell Cycle Arrest

(2016) Vaishali Kapoor et al.   PHYTOTHERAPY RESEARCH

Targeting cancer stem cells and signaling pathways by phytochemicals: Novel approach for breast cancer therapy

(2016) Prasad R. Dandawate et al.   SEMINARS IN CANCER BIOLOGY

Dietary phytochemicals as epigenetic modifiers in cancer: Promise and challenges

(2016) Eswar Shankar et al.   SEMINARS IN CANCER BIOLOGY

Apigenin enhances the cisplatin cytotoxic effect through p53-modulated apoptosis

(2016) Rui Liu et al.   Oncology Letters

Ultrasound-Mediated Microbubble Destruction (UMMD) Facilitates the Delivery of CA19-9 Targeted and Paclitaxel Loaded mPEG-PLGA-PLL Nanoparticles in Pancreatic Cancer

(2016) Lingxi Xing et al.   Theranostics

Cancer Therapy by Catechins Involves Redox Cycling of Copper Ions and Generation of Reactive Oxygen Species

(2016) Mohd Farhan et al.   Toxins

Therapeutic Effectiveness of Anticancer Phytochemicals on Cancer Stem Cells

(2016) Jisun Oh et al.   Toxins

Chemomodulatory Potential of Bartogenic Acid Against DMBA/Croton Oil Induced Two-Step Skin Carcinogenesis in Mice

(2016) Chandragouda R. Patil et al.   Journal of Cancer

Disease Subtype–Independent Biomarkers of Breast Cancer Chemoprevention by the Ayurvedic Medicine Phytochemical Withaferin A

(2016) Suman K. Samanta et al.   JNCI-Journal of the National Cancer Institute

The Chemopreventive Phytochemical Moringin Isolated from Moringa oleifera Seeds Inhibits JAK/STAT Signaling

(2016) Carina Michl et al.   PLoS One

Self-Monitoring and Self-Delivery of Photosensitizer-Doped Nanoparticles for Highly Effective Combination Cancer Therapy in Vitro and in Vivo

(2015) Jinfeng Zhang et al.   ACS Nano

The DNA Damage Response: Implications for Tumor Responses to Radiation and Chemotherapy

(2015) Michael Goldstein et al.   Annual Review of Medicine

Bioactivity of genistein: A review of in vitro and in vivo studies

(2015) Ajaz Ahmad Ganai et al.   BIOMEDICINE & PHARMACOTHERAPY

Vincristine activates c-Jun N-terminal kinase in chronic lymphocytic leukaemiain vivo

(2015) Darcy J. P. Bates et al.   BRITISH JOURNAL OF CLINICAL PHARMACOLOGY

Effective suppression of pro-inflammatory molecules by DHCA via IKK-NF-κB pathway,in vitroandin vivo

(2015) Junghun Lee et al.   BRITISH JOURNAL OF PHARMACOLOGY

Overall survival in patients with metastatic melanoma

(2015) Xue Song et al.   CURRENT MEDICAL RESEARCH AND OPINION

Inhibition of pancreatic cancer cell migration by plasma anthocyanins isolated from healthy volunteers receiving an anthocyanin-rich berry juice

(2015) Sabine Kuntz et al.   EUROPEAN JOURNAL OF NUTRITION

7-Hydroxydehydronuciferine induces human melanoma death via triggering autophagy and apoptosis

(2015) Pei-Fang Wu et al.   EXPERIMENTAL DERMATOLOGY

Resveratrol-loaded polymeric nanoparticles suppress glucose metabolism and tumor growth in vitro and in vivo

(2015) Kyung-Ho Jung et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Ultradeformable liposomes as multidrug carrier of resveratrol and 5-fluorouracil for their topical delivery

(2015) Donato Cosco et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Gold-conjugated green tea nanoparticles for enhanced anti-tumor activities and hepatoprotection — synthesis, characterization and in vitro evaluation

(2015) Sudeshna Mukherjee et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

The Multifaceted Role of Curcumin in Cancer Prevention and Treatment

(2015) Muthu Shanmugam et al.   MOLECULES

Curcumin inhibits cell proliferation and induces apoptosis of human non-small cell lung cancer cells through the upregulation of miR-192-5p and suppression of PI3K/Akt signaling pathway

(2015) HAI JIN et al.   ONCOLOGY REPORTS

Estimation of Life-Year Loss and Lifetime Costs for Different Stages of Colon Adenocarcinoma in Taiwan

(2015) Po-Chuan Chen et al.   PLoS One

Indole-3-carbinol suppresses NF-κB activity and stimulates the p53 pathway in pre-B acute lymphoblastic leukemia cells

(2015) Majid Safa et al.   TUMOR BIOLOGY

Isothiocyanates: a class of bioactive metabolites with chemopreventive potential

(2015) Gaurav Kumar et al.   TUMOR BIOLOGY

Ginger and Its Constituents: Role in Prevention and Treatment of Gastrointestinal Cancer

(2015) Sahdeo Prasad et al.   Gastroenterology Research and Practice

Anticancer effects of crocetin in human esophageal squamous cell carcinoma KYSE-150 cells

(2015) SHENG LI et al.   Oncology Letters

The potential utility of acetyltanshinone IIA in the treatment of HER2-overexpressed breast cancer: Induction of cancer cell death by targeting apoptotic and metabolic signaling pathways

(2015) Mounia Guerram et al.   Oncotarget

CancerHSP: anticancer herbs database of systems pharmacology

(2015) Weiyang Tao et al.   Scientific Reports

Genistein and Cancer: Current Status, Challenges, and Future Directions

(2015) Carmela Spagnuolo et al.   Advances in Nutrition

Evaluation of Synergetic Anticancer Activity of Berberine and Curcumin on Different Models of A549, Hep-G2, MCF-7, Jurkat, and K562 Cell Lines

(2015) Acharya Balakrishna et al.   Biomed Research International

Modulation of MicroRNAs by Phytochemicals in Cancer: Underlying Mechanisms and Translational Significance

(2015) Sanjeev K. Srivastava et al.   Biomed Research International

SC-III3, a novel scopoletin derivative, induces cytotoxicity in hepatocellular cancer cells through oxidative DNA damage and ataxia telangiectasia-mutated nuclear protein kinase activation

(2015) Peng Zhao et al.   BMC CANCER

Targeting Mortalin by Embelin Causes Activation of Tumor Suppressor p53 and Deactivation of Metastatic Signaling in Human Breast Cancer Cells

(2015) Nupur Nigam et al.   PLoS One

Chemopreventive apigenin controls UVB-induced cutaneous proliferation and angiogenesis through HuR and thrombospondin-1

(2015) Xin Tong et al.   Oncotarget

Polyethylene Glycol Conjugated Polymeric Nanocapsules for Targeted Delivery of Quercetin to Folate-Expressing Cancer Cells in Vitro and in Vivo

(2014) Riham I. El-Gogary et al.   ACS Nano

Capsaicin induces apoptosis in human small cell lung cancer via the TRPV6 receptor and the calpain pathway

(2014) Jamie K. Lau et al.   APOPTOSIS

Inhibition of HDAC increases the senescence induced by natural polyphenols in glioma cells

(2014) José E. Vargas et al.   Biochemistry and Cell Biology

Green tea polyphenol EGCG suppresses Wnt/β-catenin signaling by promoting GSK-3β- and PP2A-independent β-catenin phosphorylation/degradation

(2014) Sangtaek Oh et al.   BIOFACTORS

Anti-cancer activity of curcumin loaded nanoparticles in prostate cancer

(2014) Murali M. Yallapu et al.   BIOMATERIALS

Predicting response and survival in chemotherapy-treated triple-negative breast cancer

(2014) A Prat et al.   BRITISH JOURNAL OF CANCER

Epigenetic regulation by selected dietary phytochemicals in cancer chemoprevention

(2014) Samriddhi Shukla et al.   CANCER LETTERS

Luteolin Nanoparticle in Chemoprevention: In Vitro and In Vivo Anticancer Activity

(2014) D. Majumdar et al.   Cancer Prevention Research

The selective cytotoxicity elicited by phytochemical extract from Senecio graveolens (Asteraceae) on breast cancer cells is enhanced by hypoxia

(2014) CARLOS ECHIBURÚ-CHAU et al.   INTERNATIONAL JOURNAL OF ONCOLOGY

Berries: Anti-inflammatory Effects in Humans

(2014) Shama V. Joseph et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Targeting Microtubules by Natural Agents for Cancer Therapy

(2014) E. Mukhtar et al.   MOLECULAR CANCER THERAPEUTICS

Multifunctional Nanoparticles as Nanocarrier for Vincristine Sulfate Delivery To Overcome Tumor Multidrug Resistance

(2014) Yuan Wang et al.   MOLECULAR PHARMACEUTICS

EGCG Enhances the Efficacy of Cisplatin by Downregulating hsa-miR-98-5p in NSCLC A549 Cells

(2014) Dong-Hu Zhou et al.   NUTRITION AND CANCER-AN INTERNATIONAL JOURNAL

Curcumin and Dimethoxycurcumin Induced Epigenetic Changes in Leukemia Cells

(2014) Hazem E. Hassan et al.   PHARMACEUTICAL RESEARCH

Circadian time-dependent chemopreventive potential of withaferin-A in 7,12-dimethyl-benz[a]anthracene-induced oral carcinogenesis

(2014) Shanmugam Manoharan et al.   Pharmacological Reports

Tumor Dynamics in Response to Antiangiogenic Therapy with Oral Metronomic Topotecan and Pazopanib in Neuroblastoma Xenografts

(2014) Sushil Kumar et al.   Translational Oncology

Plant Phytochemicals as Epigenetic Modulators: Role in Cancer Chemoprevention

(2013) Vijay S. Thakur et al.   AAPS Journal

Genistein downregulates onco-miR-1260b and inhibits Wnt-signalling in renal cancer cells

(2013) H Hirata et al.   BRITISH JOURNAL OF CANCER

Bioavailability of phytochemicals and its enhancement by drug delivery systems

(2013) Farrukh Aqil et al.   CANCER LETTERS

Ginger: Is it Ready for Prime Time?

(2013) G. D. Stoner   Cancer Prevention Research

Resveratrol induces apoptosis of pancreatic cancers cells by inhibiting miR-21 regulation of BCL-2 expression

(2013) P. Liu et al.   Clinical & Translational Oncology

Genistein Down-Regulates miR-223 Expression in Pancreatic Cancer Cells

(2013) Jia Ma et al.   CURRENT DRUG TARGETS

Synergistic inhibition of breast cancer metastasis by silibinin-loaded lipid nanoparticles containing TPGS

(2013) Pengfei Xu et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Risk of Therapy-Related Secondary Leukemia in Hodgkin Lymphoma: The Stanford University Experience Over Three Generations of Clinical Trials

(2013) Michael Zach Koontz et al.   JOURNAL OF CLINICAL ONCOLOGY

Enhanced cytotoxicity of optimized liposomal genistein via specific induction of apoptosis in breast, ovarian and prostate carcinomas

(2013) Vu Phan et al.   JOURNAL OF DRUG TARGETING

Anti-cancer effects of naturally occurring compounds through modulation of signal transduction and miRNA expression in human colon cancer cells

(2013) Minami Kumazaki et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

Application of nanotechnology in improving bioavailability and bioactivity of diet-derived phytochemicals

(2013) Shu Wang et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

Triptolide Induces the Expression of miR-142-3p: A Negative Regulator of Heat Shock Protein 70 and Pancreatic Cancer Cell Proliferation

(2013) T. N. MacKenzie et al.   MOLECULAR CANCER THERAPEUTICS

Apigenin Sensitizes Colon Cancer Cells to Antitumor Activity of ABT-263

(2013) H. Shao et al.   MOLECULAR CANCER THERAPEUTICS

Withaferin A inhibits experimental epithelial-mesenchymal transition in MCF-10A cells and suppresses vimentin protein level in vivo in breast tumors

(2013) Joomin Lee et al.   MOLECULAR CARCINOGENESIS

Tubulin-based Structure-affinity Relationships for Antimitotic Vinca Alkaloids

(2012) Claire Coderch et al.   Anti-Cancer Agents in Medicinal Chemistry

Influence of Quercetin-Rich Food Intake on microRNA Expression in Lung Cancer Tissues

(2012) T. K. Lam et al.   CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION

Nanotechnology-based combinational drug delivery: an emerging approach for cancer therapy

(2012) Priyambada Parhi et al.   DRUG DISCOVERY TODAY

Capsaicin inhibits benzo(a)pyrene-induced lung carcinogenesis in an in vivo mouse model

(2012) P. Anandakumar et al.   INFLAMMATION RESEARCH

Uptake and metabolism of olive oil polyphenols in human breast cancer cells using nano-liquid chromatography coupled to electrospray ionization–time of flight-mass spectrometry

(2012) Rocío García-Villalba et al.   JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES

Withaferin A Synergizes the Therapeutic Effect of Doxorubicin through ROS-Mediated Autophagy in Ovarian Cancer

(2012) Miranda Y. Fong et al.   PLoS One

Genistein Suppresses Prostate Cancer Growth through Inhibition of Oncogenic MicroRNA-151

(2012) Takeshi Chiyomaru et al.   PLoS One

Differential Activities of the Two Closely Related Withanolides, Withaferin A and Withanone: Bioinformatics and Experimental Evidences

(2012) Kirti Vaishnavi et al.   PLoS One

EGCG protects endothelial cells against PCB 126-induced inflammation through inhibition of AhR and induction of Nrf2-regulated genes

(2012) Sung Gu Han et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

The Prospective Role of Plant Products in Radiotherapy of Cancer: A Current Overview

(2012) Banasri Hazra et al.   Frontiers in Pharmacology

Epigenetic CpG Demethylation of the Promoter and Reactivation of the Expression of Neurog1 by Curcumin in Prostate LNCaP Cells

(2011) Limin Shu et al.   AAPS Journal

Cyclodextrin-Based Nanosponges for Delivery of Resveratrol: In Vitro Characterisation, Stability, Cytotoxicity and Permeation Study

(2011) Khalid A. Ansari et al.   AAPS PHARMSCITECH

Synergistic Effects of Irinotecan and Flavonoids on Ehrlich Ascites Tumour-Bearing Mice

(2011) Anica Horvat Knežević et al.   BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY

Benefits of whole ginger extract in prostate cancer

(2011) Prasanthi Karna et al.   BRITISH JOURNAL OF NUTRITION

Indole-3-carbinol inhibited tobacco smoke carcinogen-induced lung adenocarcinoma in A/J mice when administered during the post-initiation or progression phase of lung tumorigenesis

(2011) Xuemin Qian et al.   CANCER LETTERS

Randomized Phase II Trial of Lyophilized Strawberries in Patients with Dysplastic Precancerous Lesions of the Esophagus

(2011) T. Chen et al.   Cancer Prevention Research

Chemopreventive effects of dietary phytochemicals against cancer invasion and metastasis: Phenolic acids, monophenol, polyphenol, and their derivatives

(2011) Chia-Jui Weng et al.   CANCER TREATMENT REVIEWS

(-)-Epigallocatechin-3-gallate reactivates silenced tumor suppressor genes, Cip1/p21 and p16INK4a, by reducing DNA methylation and increasing histones acetylation in human skin cancer cells

(2011) V. Nandakumar et al.   CARCINOGENESIS

Green tea polyphenol EGCG suppresses lung cancer cell growth through upregulating miR-210 expression caused by stabilizing HIF-1 

(2011) H. Wang et al.   CARCINOGENESIS

Cancer Chemoprevention by Targeting the Epigenome

(2011) Joseph Huang et al.   CURRENT DRUG TARGETS

Role of Lycopene in the Control of ROS-Mediated Cell Growth: Implications in Cancer Prevention

(2011) P. Palozza et al.   CURRENT MEDICINAL CHEMISTRY

Evaluation of the Stability and Antioxidant Activity of Nanoencapsulated Resveratrol during in Vitro Digestion

(2011) Mariarenata Sessa et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Rhodiola rosea extracts and salidroside decrease the growth of bladder cancer cell lines via inhibition of the mTOR pathway and induction of autophagy

(2011) Zhongbo Liu et al.   MOLECULAR CARCINOGENESIS

Anti-proliferative effect of curcumin on melanoma cells is mediated by PDE1A inhibition that regulates the epigenetic integrator UHRF1

(2011) Abdurazzag Abusnina et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Research on tea and health

(2011) Chung S. Yang et al.   PHARMACOLOGICAL RESEARCH

(−)-Oleocanthal as a c-Met Inhibitor for the Control of Metastatic Breast and Prostate Cancers

(2011) Ahmed Elnagar et al.   PLANTA MEDICA

Apoptosis of human fibrosarcoma HT-1080 cells by epigallocatechin-3-O-gallate via induction of p53 and caspases as well as suppression of Bcl-2 and phosphorylated nuclear factor-κB

(2010) Mi Hee Lee et al.   APOPTOSIS

Resveratrol modulates the levels of microRNAs targeting genes encoding tumor-suppressors and effectors of TGFβ signaling pathway in SW480 cells

(2010) Esmerina Tili et al.   BIOCHEMICAL PHARMACOLOGY

Cancer chemoprevention by dietary polyphenols: Promising role for epigenetics

(2010) Alexander Link et al.   BIOCHEMICAL PHARMACOLOGY

Development of curcumin as an epigenetic agent

(2010) Siqing Fu et al.   CANCER

Pharmacokinetics, oral bioavailability, and metabolic profile of resveratrol and its dimethylether analog, pterostilbene, in rats

(2010) Izet M. Kapetanovic et al.   CANCER CHEMOTHERAPY AND PHARMACOLOGY

A novel compound modified from tanshinone inhibits tumor growth in vivo via activation of the intrinsic apoptotic pathway

(2010) Hong-Lei Tian et al.   CANCER LETTERS

Capsaicin: A novel chemopreventive molecule and its underlying molecular mechanisms of action

(2010) AA Oyagbemi et al.   INDIAN JOURNAL OF CANCER

Drug delivery and nanoparticles: Applications and hazards

(2010) de Jong   International Journal of Nanomedicine

Anti-invasion effect of rosmarinic acid via the extracellular signal-regulated kinase and oxidation-reduction pathway in Ls174-T cells

(2010) Yichun Xu et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Distinct Combinatorial Effects of the Plant Polyphenols Curcumin, Carnosic Acid, and Silibinin on Proliferation and Apoptosis in Acute Myeloid Leukemia Cells

(2010) Stella Pesakhov et al.   NUTRITION AND CANCER-AN INTERNATIONAL JOURNAL

Hydroxytyrosol: from laboratory investigations to future clinical trials

(2010) Sergio Granados-Principal et al.   NUTRITION REVIEWS

Antitumour effects of phyllanthus emblica L.: Induction of cancer cell apoptosis and Inhibition of in vivo tumour promotion and in vitro invasion of human cancer cells

(2010) C. Ngamkitidechakul et al.   PHYTOTHERAPY RESEARCH

Selective Killing of Cancer Cells by Ashwagandha Leaf Extract and Its Component Withanone Involves ROS Signaling

(2010) Nashi Widodo et al.   PLoS One

Anthocyanins in Black Raspberries Prevent Esophageal Tumors in Rats

(2009) L.-S. Wang et al.   Cancer Prevention Research

Foodstuffs for Preventing Cancer: The Preclinical and Clinical Development of Berries

(2009) G. D. Stoner   Cancer Prevention Research

Cancer Prevention and Treatment with Resveratrol: From Rodent Studies to Clinical Trials

(2009) A. Bishayee   Cancer Prevention Research

Introducing Nanochemoprevention as a Novel Approach for Cancer Control: Proof of Principle with Green Tea Polyphenol Epigallocatechin-3-Gallate

(2009) I. A. Siddiqui et al.   CANCER RESEARCH

Anti-proliferative and apoptotic effects of oleuropein and hydroxytyrosol on human breast cancer MCF-7 cells

(2009) Junkyu Han et al.   CYTOTECHNOLOGY

Characterization and quantification of phenolic compounds of extra-virgin olive oils with anticancer properties by a rapid and resolutive LC-ESI-TOF MS method

(2009) Rocío García-Villalba et al.   JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS

Curcumin reduces the expression of Bcl-2 by upregulating miR-15a and miR-16 in MCF-7 cells

(2009) Jie Yang et al.   MEDICAL ONCOLOGY

Black Raspberry Components Inhibit Proliferation, Induce Apoptosis, and Modulate Gene Expression in Rat Esophageal Epithelial Cells

(2009) Nancy N. Zikri et al.   NUTRITION AND CANCER-AN INTERNATIONAL JOURNAL

Metabolic constituents of grapevine and grape-derived products

(2009) Kashif Ali et al.   PHYTOCHEMISTRY REVIEWS

Concurrent chemo-radiotherapy following neoadjuvant chemotherapy in locally advanced breast cancer

(2009) Alberto Alvarado-Miranda et al.   Radiation Oncology

Curcumin is a potent DNA hypomethylation agent

(2008) Zhongfa Liu et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

tabAnti-HER2 (erbB-2) oncogene effects of phenolic compounds directly isolated from commercial Extra-Virgin Olive Oil (EVOO)

(2008) Javier A Menendez et al.   BMC CANCER

Quercetin Is Able to Demethylate the p16INK4a Gene Promoter

(2008) Sainan Tan et al.   CHEMOTHERAPY

Protective role of Withaferin-A on immunoexpression of p53 and bcl-2 in 7,12-dimethylbenz(a)anthracene-induced experimental oral carcinogenesis

(2008) Kuppusamy Panjamurthy et al.   INVESTIGATIONAL NEW DRUGS

Berry Fruits for Cancer Prevention: Current Status and Future Prospects

(2008) Navindra P. Seeram   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Enhancement of p53 expression in keratinocytes by the bioflavonoid apigenin is associated with RNA-binding protein HuR

(2008) Xin Tong et al.   MOLECULAR CARCINOGENESIS

Cancer chemoprevention and chemotherapy: Dietary polyphenols and signalling pathways

(2008) Sonia Ramos   MOLECULAR NUTRITION & FOOD RESEARCH

In vivoprotective effect of crocetin on benzo(a)pyrene-induced lung cancer in Swiss albino mice

(2008) Venkatraman Magesh et al.   PHYTOTHERAPY RESEARCH

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