Bidirectional relationship between sleep and Alzheimer’s disease: role of amyloid, tau, and other factors

Obstructive sleep apnea treatment, slow wave activity, and amyloid-β

(2019) Yo-El S. Ju et al.   ANNALS OF NEUROLOGY

Abnormal Sleep Behaviours Across the Spectrum of Alzheimer’s Disease Severity: Influence of APOE Genotypes and Lewy Bodies

(2019) HBSc Ka Yi G. Koo et al.   Current Alzheimer Research

Secreted amyloid-β precursor protein functions as a GABABR1a ligand to modulate synaptic transmission

(2019) Heather C. Rice et al.   SCIENCE

Reduced non–rapid eye movement sleep is associated with tau pathology in early Alzheimer’s disease

(2019) Brendan P. Lucey et al.   Science Translational Medicine

Sleep-Wake Regulation and the Hallmarks of the Pathogenesis of Alzheimer’s Disease

(2019) M Van Egroo et al.   SLEEP

The sleep-wake cycle regulates brain interstitial fluid tau in mice and CSF tau in humans

(2019) Jerrah K. Holth et al.   SCIENCE

Sleep oscillation-specific associations with Alzheimer’s disease CSF biomarkers: novel roles for sleep spindles and tau

(2019) Korey Kam et al.   Molecular Neurodegeneration

Rocking Promotes Sleep in Mice through Rhythmic Stimulation of the Vestibular System

(2019) Konstantinos Kompotis et al.   CURRENT BIOLOGY

Whole-Night Continuous Rocking Entrains Spontaneous Neural Oscillations with Benefits for Sleep and Memory

(2019) Aurore A. Perrault et al.   CURRENT BIOLOGY

Sleep as a potential biomarker of tau and β-amyloid burden in the human brain

(2019) Joseph R. Winer et al.   JOURNAL OF NEUROSCIENCE

Effect of sleep on overnight cerebrospinal fluid amyloid β kinetics

(2018) Brendan P. Lucey et al.   ANNALS OF NEUROLOGY

REM Sleep Behavior Disorder and Alzheimer’s Disease: Definitely No Relationship?

(2018) Andrea Galbiati et al.   JOURNAL OF ALZHEIMERS DISEASE

Tau can switch microtubule network organizations: from random networks to dynamic and stable bundles

(2018) Elea Prezel et al.   MOLECULAR BIOLOGY OF THE CELL

Sleep and Alzheimer's disease: A pivotal role for the suprachiasmatic nucleus

(2018) Jan Van Erum et al.   SLEEP MEDICINE REVIEWS

Reconsideration of Amyloid Hypothesis and Tau Hypothesis in Alzheimer's Disease

(2018) Fuyuki Kametani et al.   Frontiers in Neuroscience

In Search of an Identity for Amyloid Plaques

(2018) Tien-Phat V. Huynh et al.   TRENDS IN NEUROSCIENCES

New insights into the role of TREM2 in Alzheimer’s disease

(2018) Maud Gratuze et al.   Molecular Neurodegeneration

Microglia in Alzheimer's Disease: Risk Factors and Inflammation

(2018) Atsuko Katsumoto et al.   Frontiers in Neurology

Orexin Impairs the Phagocytosis and Degradation of Amyloid-β Fibrils by Microglial Cells

(2017) Hoyoung An et al.   JOURNAL OF ALZHEIMERS DISEASE

Alzheimer’s disease: A matter of blood–brain barrier dysfunction?

(2017) Axel Montagne et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Apolipoprotein E and Alzheimer’s disease: the influence of apolipoprotein E on amyloid-β and other amyloidogenic proteins

(2017) Tien-Phat V. Huynh et al.   JOURNAL OF LIPID RESEARCH

Sleep Loss Promotes Astrocytic Phagocytosis and Microglial Activation in Mouse Cerebral Cortex

(2017) Michele Bellesi et al.   JOURNAL OF NEUROSCIENCE

ApoE4 markedly exacerbates tau-mediated neurodegeneration in a mouse model of tauopathy

(2017) Yang Shi et al.   NATURE

Amyloid-β plaques enhance Alzheimer's brain tau-seeded pathologies by facilitating neuritic plaque tau aggregation

(2017) Zhuohao He et al.   NATURE MEDICINE

Poor sleep is associated with CSF biomarkers of amyloid pathology in cognitively normal adults

(2017) Kate E. Sprecher et al.   NEUROLOGY

Sleep, sleep deprivation, autonomic nervous system and cardiovascular diseases

(2017) Eleonora Tobaldini et al.   NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS

TREM2 deficiency attenuates neuroinflammation and protects against neurodegeneration in a mouse model of tauopathy

(2017) Cheryl E. G. Leyns et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Bright light therapy for sleep disturbance in dementia is most effective for mild to moderate Alzheimer's type dementia: a case series

(2017) Hirotaka Sekiguchi et al.   Psychogeriatrics

Sleep Disturbance, Cognitive Decline, and Dementia: A Review

(2017) Mark Wu et al.   SEMINARS IN NEUROLOGY

Obstructive Sleep Apnea is Associated With Early but Possibly Modifiable Alzheimer’s Disease Biomarkers Changes

(2017) Claudio Liguori et al.   SLEEP

Bright light therapy for sleep disturbance in dementia is most effective for mild to moderate Alzheimer's type dementia: a case series

(2017) Hirotaka Sekiguchi et al.   Psychogeriatrics

Role of Sleep Disturbance in the Trajectory of Alzheimer’s Disease

(2017) Dong Woo Kang et al.   Clinical Psychopharmacology and Neuroscience

Altered sleep and EEG power in the P301S Tau transgenic mouse model

(2017) Jerrah K. Holth et al.   Annals of Clinical and Translational Neurology

Obstructive Sleep Apnea is Associated With Early but Possibly Modifiable Alzheimer’s Disease Biomarkers Changes

(2017) Claudio Liguori et al.   SLEEP

Lack of Association of the APOE ε4 Allele with the Risk of Obstructive Sleep Apnea: Meta-Analysis and Meta-Regression

(2017) Tushar P. Thakre et al.   SLEEP

Short or Long Sleep Duration Is Associated with Memory Impairment in Older Chinese: the Guangzhou Biobank Cohort Study

(2017) Lin Xu et al.   SLEEP

2016 Alzheimer's disease facts and figures

(2016)   Alzheimers & Dementia

Obstructive sleep apnea decreases central nervous system-derived proteins in the cerebrospinal fluid

(2016) Yo-El S. Ju et al.   ANNALS OF NEUROLOGY

Association of sleep apnea and sleep duration with peripheral artery disease: The Multi-Ethnic Study of Atherosclerosis (MESA)

(2016) Mako Nagayoshi et al.   ATHEROSCLEROSIS

The Cellular Phase of Alzheimer’s Disease

(2016) Bart De Strooper et al.   CELL

The amyloid hypothesis of Alzheimer's disease at 25 years

(2016) Dennis J Selkoe et al.   EMBO Molecular Medicine

Apolipoprotein E ɛ2/ɛ3/ɛ4 variant in association with obstructive sleep apnoea and lipid profile: A meta-analysis

(2016) Zhuoqiang Lu et al.   JOURNAL OF INTERNATIONAL MEDICAL RESEARCH

Disease Progression-Dependent Effects of TREM2 Deficiency in a Mouse Model of Alzheimer's Disease

(2016) Taylor R. Jay et al.   JOURNAL OF NEUROSCIENCE

Electroencephalogram slowing predicts neurodegeneration in rapid eye movement sleep behavior disorder

(2016) Jessica Rodrigues Brazète et al.   NEUROBIOLOGY OF AGING

Rapid eye movement sleep disruption and sleep fragmentation are associated with increased orexin-A cerebrospinal-fluid levels in mild cognitive impairment due to Alzheimer's disease

(2016) Claudio Liguori et al.   NEUROBIOLOGY OF AGING

Relationships between sleep quality and brain volume, metabolism, and amyloid deposition in late adulthood

(2016) Pierre Branger et al.   NEUROBIOLOGY OF AGING

Evidence of association between sleep quality and APOE ε4 in healthy older adults

(2016) Lauren L. Drogos et al.   NEUROLOGY

Tau and Aβ imaging, CSF measures, and cognition in Alzheimer’s disease

(2016) Matthew R. Brier et al.   Science Translational Medicine

The Relationship between Sleep Quality and Brain Amyloid Burden

(2016) Belinda M. Brown et al.   SLEEP

Drug development in Alzheimer’s disease: the path to 2025

(2016) Jeffrey Cummings et al.   Alzheimers Research & Therapy

The Relationship between Sleep Quality and Brain Amyloid Burden

(2016) Belinda M. Brown et al.   SLEEP

Apolipoprotein E levels and Alzheimer risk

(2015) Bradley T. Hyman et al.   ANNALS OF NEUROLOGY

Precortical Phase of Alzheimer's Disease (AD)-Related Tau Cytoskeletal Pathology

(2015) Katharina Stratmann et al.   BRAIN PATHOLOGY

Quantitative EEG of Rapid-Eye-Movement Sleep

(2015) Pauline Brayet et al.   CLINICAL EEG AND NEUROSCIENCE

Aging in Down Syndrome and the Development of Alzheimer's Disease Neuropathology

(2015) Elizabeth Head et al.   Current Alzheimer Research

TREM2 deficiency eliminates TREM2+inflammatory macrophages and ameliorates pathology in Alzheimer’s disease mouse models

(2015) Taylor R. Jay et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Qualitative changes in human γ-secretase underlie familial Alzheimer’s disease

(2015) Maria Szaruga et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Neuroinflammation in Alzheimer's disease

(2015) Michael T Heneka et al.   LANCET NEUROLOGY

Rescue of long-range circuit dysfunction in Alzheimer's disease models

(2015) Marc Aurel Busche et al.   NATURE NEUROSCIENCE

Three dimensions of the amyloid hypothesis: time, space and 'wingmen'

(2015) Erik S Musiek et al.   NATURE NEUROSCIENCE

β-amyloid disrupts human NREM slow waves and related hippocampus-dependent memory consolidation

(2015) Bryce A Mander et al.   NATURE NEUROSCIENCE

Progressive age-related changes in sleep and EEG profiles in the PLB1Triple mouse model of Alzheimer’s disease

(2015) Amar Jyoti et al.   NEUROBIOLOGY OF AGING

Amyloid burden is associated with self-reported sleep in nondemented late middle-aged adults

(2015) Kate E. Sprecher et al.   NEUROBIOLOGY OF AGING

Genetic Disorders with Tau Pathology: A Review of the Literature and Report of Two Patients with Tauopathy and Positive Family Histories

(2015) Pawel Tacik et al.   Neurodegenerative Diseases

Sleep-disordered breathing advances cognitive decline in the elderly

(2015) R. S. Osorio et al.   NEUROLOGY

Blood-Brain Barrier Breakdown in the Aging Human Hippocampus

(2015) Axel Montagne et al.   NEURON

Increased fragmentation of sleep–wake cycles in the 5XFAD mouse model of Alzheimer’s disease

(2015) M. Sethi et al.   NEUROSCIENCE

Tau stabilizes microtubules by binding at the interface between tubulin heterodimers

(2015) Harindranath Kadavath et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Alzheimer's disease

(2015) Colin L. Masters et al.   Nature Reviews Disease Primers

Sleep-Wake Cycle Dysfunction in the TgCRND8 Mouse Model of Alzheimer’s Disease: From Early to Advanced Pathological Stages

(2015) Jessica Colby-Milley et al.   PLoS One

Associations of allostatic load with sleep apnea, insomnia, short sleep duration, and other sleep disturbances: findings from the National Health and Nutrition Examination Survey 2005 to 2008

(2014) Xiaoli Chen et al.   ANNALS OF EPIDEMIOLOGY

Behavioral assays with mouse models of Alzheimer's disease: Practical considerations and guidelines

(2014) Daniela Puzzo et al.   BIOCHEMICAL PHARMACOLOGY

Alzheimer disease: Epidemiology, diagnostic criteria, risk factors and biomarkers

(2014) Christiane Reitz et al.   BIOCHEMICAL PHARMACOLOGY

Sleep is related to neuron numbers in the ventrolateral preoptic/intermediate nucleus in older adults with and without Alzheimer’s disease

(2014) Andrew S. P. Lim et al.   BRAIN

Potential role of orexin and sleep modulation in the pathogenesis of Alzheimer’s disease

(2014) Jee Hoon Roh et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Neuronal activity regulates extracellular tau in vivo

(2014) Kaoru Yamada et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Sleep Restriction Impairs Blood-Brain Barrier Function

(2014) J. He et al.   JOURNAL OF NEUROSCIENCE

CSF beta-amyloid levels are altered in narcolepsy: a link with the inflammatory hypothesis?

(2014) Claudio Liguori et al.   JOURNAL OF SLEEP RESEARCH

Sleep deficits in mild cognitive impairment are related to increased levels of plasma amyloid-β and cortical thinning

(2014) Mayely P. Sanchez-Espinosa et al.   NEUROIMAGE

Symptom onset in autosomal dominant Alzheimer disease: A systematic review and meta-analysis

(2014) D. C. Ryman et al.   NEUROLOGY

Phase 3 Trials of Solanezumab for Mild-to-Moderate Alzheimer's Disease

(2014) Rachelle S. Doody et al.   NEW ENGLAND JOURNAL OF MEDICINE

Behavioral and EEG changes in male 5xFAD mice

(2014) F. Schneider et al.   PHYSIOLOGY & BEHAVIOR

Breakdown in REM sleep circuitry underlies REM sleep behavior disorder

(2014) John Peever et al.   TRENDS IN NEUROSCIENCES

Orexinergic System Dysregulation, Sleep Impairment, and Cognitive Decline in Alzheimer Disease

(2014) Claudio Liguori et al.   JAMA Neurology

Effect of 1 Night of Total Sleep Deprivation on Cerebrospinal Fluid β-Amyloid 42 in Healthy Middle-Aged Men

(2014) Sharon Ooms et al.   JAMA Neurology

A Change in Sleep Pattern May Predict Alzheimer Disease

(2013) Elizabeth A. Hahn et al.   AMERICAN JOURNAL OF GERIATRIC PSYCHIATRY

SIRT1 Mediates Central Circadian Control in the SCN by a Mechanism that Decays with Aging

(2013) Hung-Chun Chang et al.   CELL

Sleep Loss as a Factor to Induce Cellular and Molecular Inflammatory Variations

(2013) Gabriela Hurtado-Alvarado et al.   Clinical & Developmental Immunology

Valproic Acid Reduces Neuritic Plaque Formation and Improves Learning Deficits in APPSwe/PS1A246ETransgenic Mice via Preventing the Prenatal Hypoxia-Induced Down-Regulation of Neprilysin

(2013) Zheng Wang et al.   CNS Neuroscience & Therapeutics

REM Sleep Loss and Recovery Regulates Blood-Brain Barrier Function

(2013) Beatriz Gomez-Gonzalez et al.   CURRENT NEUROVASCULAR RESEARCH

Physiological release of endogenous tau is stimulated by neuronal activity

(2013) Amy M Pooler et al.   EMBO REPORTS

Alzheimer's Aβ42 and Aβ40 peptides form interlaced amyloid fibrils

(2013) Lei Gu et al.   JOURNAL OF NEUROCHEMISTRY

Differential Relationships of Reactive Astrocytes and Microglia to Fibrillar Amyloid Deposits in Alzheimer Disease

(2013) Alberto Serrano-Pozo et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

Tau pathology and neurodegeneration

(2013) Maria Grazia Spillantini et al.   LANCET NEUROLOGY

Prefrontal atrophy, disrupted NREM slow waves and impaired hippocampal-dependent memory in aging

(2013) Bryce A Mander et al.   NATURE NEUROSCIENCE

Sleep and Alzheimer disease pathology—a bidirectional relationship

(2013) Yo-El S. Ju et al.   Nature Reviews Neurology

Alzheimer disease therapy—moving from amyloid-β to tau

(2013) Ezio Giacobini et al.   Nature Reviews Neurology

Apolipoprotein E and Alzheimer disease: risk, mechanisms and therapy

(2013) Chia-Chen Liu et al.   Nature Reviews Neurology

Neural reserve, neuronal density in the locus ceruleus, and cognitive decline

(2013) R. S. Wilson et al.   NEUROLOGY

Death by a Thousand Cuts in Alzheimer’s Disease: Hypoxia—The Prodrome

(2013) Mak Adam Daulatzai   NEUROTOXICITY RESEARCH

Sleep Apnea and the Risk of Dementia: A Population-Based 5-Year Follow-Up Study in Taiwan

(2013) Wei-Pin Chang et al.   PLoS One

Profiling Murine Tau with 0N, 1N and 2N Isoform-Specific Antibodies in Brain and Peripheral Organs Reveals Distinct Subcellular Localization, with the 1N Isoform Being Enriched in the Nucleus

(2013) Chang Liu et al.   PLoS One

Garbage Truck of the Brain

(2013) M. Nedergaard   SCIENCE

Sleep Drives Metabolite Clearance from the Adult Brain

(2013) L. Xie et al.   SCIENCE

Sleep Fragmentation and the Risk of Incident Alzheimer's Disease and Cognitive Decline in Older Persons

(2013) Andrew S. P. Lim et al.   SLEEP

Modification of the Relationship of the Apolipoprotein E ε4 Allele to the Risk of Alzheimer Disease and Neurofibrillary Tangle Density by Sleep

(2013) Andrew S. P. Lim et al.   JAMA Neurology

Sleep Quality and Preclinical Alzheimer Disease

(2013) Yo-El S. Ju et al.   JAMA Neurology

The Circadian System in Alzheimer’s Disease: Disturbances, Mechanisms, and Opportunities

(2012) Andrew N. Coogan et al.   BIOLOGICAL PSYCHIATRY

Prevalence of Sleep Disturbances in Mild Cognitive Impairment and Dementing Disorders: A Multicenter Italian Clinical Cross-Sectional Study on 431 Patients

(2012) B. Guarnieri et al.   DEMENTIA AND GERIATRIC COGNITIVE DISORDERS

Involvement of spindles in memory consolidation is slow wave sleep-specific

(2012) R. Cox et al.   LEARNING & MEMORY

Prenatal hypoxia may aggravate the cognitive impairment and Alzheimer’s disease neuropathology in APPSwe/PS1A246E transgenic mice

(2012) Xin Zhang et al.   NEUROBIOLOGY OF AGING

Clinical and Biomarker Changes in Dominantly Inherited Alzheimer's Disease

(2012) Randall J. Bateman et al.   NEW ENGLAND JOURNAL OF MEDICINE

Exercise training improves sleep quality in middle-aged and older adults with sleep problems: a systematic review

(2012) Pei-Yu Yang et al.   Journal of Physiotherapy

Continuous Positive Airway Pressure Reduces Postprandial Lipidemia in Obstructive Sleep Apnea

(2011) Craig L. Phillips et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Amyloid Precursor Protein Processing and Alzheimer's Disease

(2011) Richard J. O'Brien et al.   Annual Review of Neuroscience

Mechanism of Amyloid Removal in Patients With Alzheimer Disease Treated With Gantenerumab

(2011) Susanne Ostrowitzki   ARCHIVES OF NEUROLOGY

Effects of Age and Amyloid Deposition on Aβ Dynamics in the Human Central Nervous System

(2011) Yafei Huang   ARCHIVES OF NEUROLOGY

Differential degeneration of the locus coeruleus in dementia subtypes

(2011) H. Brunnström et al.   CLINICAL NEUROPATHOLOGY

Rocking synchronizes brain waves during a short nap

(2011) Laurence Bayer et al.   CURRENT BIOLOGY

Direct evidence of phosphorylated neuronal intermediate filament proteins in neurofibrillary tangles (NFTs): phosphoproteomics of Alzheimer's NFTs

(2011) Parvathi Rudrabhatla et al.   FASEB JOURNAL

Obstructive Sleep Apnea

(2011) Rodrigo P. Pedrosa et al.   HYPERTENSION

Stages of the Pathologic Process in Alzheimer Disease: Age Categories From 1 to 100 Years

(2011) Heiko Braak et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

Apolipoprotein E in Alzheimer's disease and other neurological disorders

(2011) Philip B Verghese et al.   LANCET NEUROLOGY

Neurovascular pathways to neurodegeneration in Alzheimer's disease and other disorders

(2011) Berislav V. Zlokovic   NATURE REVIEWS NEUROSCIENCE

Abnormal Cognition, Sleep, EEG and Brain Metabolism in a Novel Knock-In Alzheimer Mouse, PLB1

(2011) Bettina Platt et al.   PLoS One

The pathological process underlying Alzheimer’s disease in individuals under thirty

(2010) Heiko Braak et al.   ACTA NEUROPATHOLOGICA

The Role of Tau in Alzheimer's Disease and Related Disorders

(2010) Rodrigo Medeiros et al.   CNS Neuroscience & Therapeutics

Microglia dynamics and function in the CNS

(2010) Christopher N Parkhurst et al.   CURRENT OPINION IN NEUROBIOLOGY

Review Article: Genetics of Alzheimer Disease

(2010) Lynn M. Bekris et al.   JOURNAL OF GERIATRIC PSYCHIATRY AND NEUROLOGY

Sleep disorders in aging and dementia

(2010) S. Bombois et al.   Journal of Nutrition Health & Aging

Frequency and Correlates of Caregiver-Reported Sleep Disturbances in a Sample of Persons with Early Dementia

(2010) Arvid Rongve et al.   JOURNAL OF THE AMERICAN GERIATRICS SOCIETY

Alzheimer's disease: clinical trials and drug development

(2010) Francesca Mangialasche et al.   LANCET NEUROLOGY

Sleep State Switching

(2010) Clifford B. Saper et al.   NEURON

Decreased Clearance of CNS  -Amyloid in Alzheimer's Disease

(2010) K. G. Mawuenyega et al.   SCIENCE

Apolipoprotein E-dependent accumulation of Alzheimer disease-related lesions begins in middle age

(2009) Eloise Kok et al.   ANNALS OF NEUROLOGY

Mild cognitive impairment in rapid eye movement sleep behavior disorder and Parkinson's disease

(2009) Jean-François Gagnon et al.   ANNALS OF NEUROLOGY

APOEpredicts amyloid-beta but not tau Alzheimer pathology in cognitively normal aging

(2009) John C. Morris et al.   ANNALS OF NEUROLOGY

Animal models reveal role for tau phosphorylation in human disease

(2009) Jürgen Götz et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

CSF Biomarkers and Incipient Alzheimer Disease in Patients With Mild Cognitive Impairment

(2009) Niklas Mattsson   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Aβ aggregation and possible implications in Alzheimer's disease pathogenesis

(2009) Prashant R. Bharadwaj et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Self-Reported Sleep Quality Predicts Poor Cognitive Performance in Healthy Older Adults

(2009) R. D. Nebes et al.   JOURNALS OF GERONTOLOGY SERIES B-PSYCHOLOGICAL SCIENCES AND SOCIAL SCIENCES

Apolipoprotein E and its receptors in Alzheimer's disease: pathways, pathogenesis and therapy

(2009) Guojun Bu   NATURE REVIEWS NEUROSCIENCE

Reduction of scale invariance of activity fluctuations with aging and Alzheimer's disease: Involvement of the circadian pacemaker

(2009) Kun Hu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Amyloid-  Dynamics Are Regulated by Orexin and the Sleep-Wake Cycle

(2009) J.-E. Kang et al.   SCIENCE

Dorsomedial SCN neuronal subpopulations subserve different functions in human dementia

(2008) D. G. Harper et al.   BRAIN

Sleep Apnea and Cardiovascular Disease

(2008) Virend K. Somers et al.   CIRCULATION

Neuropsychiatric symptoms in the community‐based patients with mild cognitive impairment and the influence of demographic factors

(2008) W. Muangpaisan et al.   INTERNATIONAL JOURNAL OF GERIATRIC PSYCHIATRY

Cognitive Effects of Treating Obstructive Sleep Apnea in Alzheimer's Disease: A Randomized Controlled Study

(2008) Sonia Ancoli-Israel et al.   JOURNAL OF THE AMERICAN GERIATRICS SOCIETY

Thirty years of Alzheimer's disease genetics: the implications of systematic meta-analyses

(2008) Lars Bertram et al.   NATURE REVIEWS NEUROSCIENCE

Amyloid precursor protein increases cortical neuron size in transgenic mice

(2008) Esther S. Oh et al.   NEUROBIOLOGY OF AGING

Cardiovascular, Inflammatory, and Metabolic Consequences of Sleep Deprivation

(2008) Janet M. Mullington et al.   PROGRESS IN CARDIOVASCULAR DISEASES

The APOE ε4 allele increases the risk of impaired spatial working memory in obstructive sleep apnea

(2008) Filomena I.I. Cosentino et al.   SLEEP MEDICINE