Secreted amyloid-β precursor protein functions as a GABABR1a ligand to modulate synaptic transmission

Not just amyloid: physiological functions of the amyloid precursor protein family

(2017) Ulrike C. Müller et al.   NATURE REVIEWS NEUROSCIENCE

Secreted amyloid precursor protein-alpha can restore novel object location memory and hippocampal LTP in aged rats

(2017) Monica Xiong et al.   NEUROBIOLOGY OF LEARNING AND MEMORY

Therapeutic Potential of Secreted Amyloid Precursor Protein APPsα

(2017) Bruce G. Mockett et al.   Frontiers in Molecular Neuroscience

Organization and functions of mGlu and GABAB receptor complexes

(2016) Jean-Philippe Pin et al.   NATURE

Network abnormalities and interneuron dysfunction in Alzheimer disease

(2016) Jorge J. Palop et al.   NATURE REVIEWS NEUROSCIENCE

Implications of GABAergic Neurotransmission in Alzheimer’s Disease

(2016) Yanfang Li et al.   Frontiers in Aging Neuroscience

Combined automated NOE assignment and structure calculation with CYANA

(2015) Peter Güntert et al.   JOURNAL OF BIOMOLECULAR NMR

η-Secretase processing of APP inhibits neuronal activity in the hippocampus

(2015) Michael Willem et al.   NATURE

Modular composition and dynamics of native GABAB receptors identified by high-resolution proteomics

(2015) Jochen Schwenk et al.   NATURE NEUROSCIENCE

The Sorting Receptor SorCS1 Regulates Trafficking of Neurexin and AMPA Receptors

(2015) Jeffrey N. Savas et al.   NEURON

GABABreceptor deficiency causes failure of neuronal homeostasis in hippocampal networks

(2015) Irena Vertkin et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Acute function of secreted amyloid precursor protein fragment APPsα in synaptic plasticity

(2014) Meike Hick et al.   ACTA NEUROPATHOLOGICA

Innervation by a GABAergic Neuron Depresses Spontaneous Release in Glutamatergic Neurons and Unveils the Clamping Phenotype of Synaptotagmin-1

(2014) K. D. B. Wierda et al.   JOURNAL OF NEUROSCIENCE

The Amyloid Precursor Protein Controls Adult Hippocampal Neurogenesis through GABAergic Interneurons

(2014) B. Wang et al.   JOURNAL OF NEUROSCIENCE

Genetic Suppression of Transgenic APP Rescues Hypersynchronous Network Activity in a Mouse Model of Alzeimer's Disease

(2014) H. A. Born et al.   JOURNAL OF NEUROSCIENCE

Ecto-Fc MS identifies ligand-receptor interactions through extracellular domain Fc fusion protein baits and shotgun proteomic analysis

(2014) Jeffrey N Savas et al.   Nature Protocols

Thy1-GCaMP6 Transgenic Mice for Neuronal Population Imaging In Vivo

(2014) Hod Dana et al.   PLoS One

Composition of isolated synaptic boutons reveals the amounts of vesicle trafficking proteins

(2014) B. G. Wilhelm et al.   SCIENCE

Comparative analysis of single and combined APP/APLP knockouts reveals reduced spine density in APP-KO mice that is prevented by APPsα expression

(2014) Sascha W Weyer et al.   Acta Neuropathologica Communications

An Extracellular Interactome of Immunoglobulin and LRR Proteins Reveals Receptor-Ligand Networks

(2013) Engin Özkan et al.   CELL

Redundancy and divergence in the amyloid precursor protein family

(2013) S. Ali M. Shariati et al.   FEBS LETTERS

Soluble amyloid-  precursor protein binds its cell surface receptor in a cooperative fashion with glypican and syndecan proteoglycans

(2013) C. Reinhard et al.   JOURNAL OF CELL SCIENCE

Analysis of the Overall Structure of the Multi-Domain Amyloid Precursor Protein (APP)

(2013) Ina Coburger et al.   PLoS One

Trafficking and Proteolytic Processing of APP

(2013) C. Haass et al.   Cold Spring Harbor Perspectives in Medicine

GABABreceptor subtypes differentially modulate synaptic inhibition in the dentate gyrus to enhance granule cell output

(2012) Joshua D Foster et al.   BRITISH JOURNAL OF PHARMACOLOGY

Amyloid precursor protein (APP) regulates synaptic structure and function

(2012) Sheue-Houy Tyan et al.   MOLECULAR AND CELLULAR NEUROSCIENCE

Regulation of neuronal GABAB receptor functions by subunit composition

(2012) Martin Gassmann et al.   NATURE REVIEWS NEUROSCIENCE

Extremely Long-Lived Nuclear Pore Proteins in the Rat Brain

(2012) J. N. Savas et al.   SCIENCE

β-Secretase cleavage is not required for generation of the intracellular C-terminal domain of the amyloid precursor family of proteins

(2010) Carlo Sala Frigerio et al.   FEBS Journal

The Sushi Domains of GABAB Receptors Function as Axonal Targeting Signals

(2010) B. Biermann et al.   JOURNAL OF NEUROSCIENCE

DANGLE: A Bayesian inferential method for predicting protein backbone dihedral angles and secondary structure

(2009) Ming-Sin Cheung et al.   JOURNAL OF MAGNETIC RESONANCE

Amyloid Precursor Protein Regulates Cav1.2 L-type Calcium Channel Levels and Function to Influence GABAergic Short-Term Plasticity

(2009) L. Yang et al.   JOURNAL OF NEUROSCIENCE

Amyloid-β as a positive endogenous regulator of release probability at hippocampal synapses

(2009) Efrat Abramov et al.   NATURE NEUROSCIENCE

LRRTM2 Interacts with Neurexin1 and Regulates Excitatory Synapse Formation

(2009) Joris de Wit et al.   NEURON

Roles of GABAB receptor subtypes in presynaptic auto- and heteroreceptor function regulating GABA and glutamate release

(2008) Peter C. Waldmeier et al.   JOURNAL OF NEURAL TRANSMISSION

Endogenous secreted amyloid precursor protein-α regulates hippocampal NMDA receptor function, long-term potentiation and spatial memory

(2008) Chanel J. Taylor et al.   NEUROBIOLOGY OF DISEASE