Valproic Acid Reduces Neuritic Plaque Formation and Improves Learning Deficits in APPSwe/PS1A246ETransgenic Mice via Preventing the Prenatal Hypoxia-Induced Down-Regulation of Neprilysin

Valproic Acid Attenuates Neuronal Loss in the Brain of APP/PS1 Double Transgenic Alzheimer’s Disease Mice Model

(2013) Zhimin Long et al.   Current Alzheimer Research

Prenatal hypoxia may aggravate the cognitive impairment and Alzheimer’s disease neuropathology in APPSwe/PS1A246E transgenic mice

(2012) Xin Zhang et al.   NEUROBIOLOGY OF AGING

Valproate reduces tau phosphorylation via cyclin-dependent kinase 5 and glycogen synthase kinase 3 signaling pathways

(2011) Jiang-Ping Hu et al.   BRAIN RESEARCH BULLETIN

Hypoxia-Induced Down-Regulation of Neprilysin by Histone Modification in Mouse Primary Cortical and Hippocampal Neurons

(2011) Zheng Wang et al.   PLoS One

Valproic acid enhances microglial phagocytosis of amyloid-β1–42

(2010) A.M. Smith et al.   NEUROSCIENCE

Valproic acid stimulates clusterin expression in human astrocytes: Implications for Alzheimer's disease

(2010) Tapio Nuutinen et al.   NEUROSCIENCE LETTERS

Pathological role of hypoxia in Alzheimer's disease

(2009) Xin Zhang et al.   EXPERIMENTAL NEUROLOGY

Amyloid-Degrading Enzymes as Therapeutic Targets in Alzheimers Disease

(2008) Natalia Nalivaeva et al.   Current Alzheimer Research

Neprilysin and Amyloid Beta Peptide Degradation

(2008) Louis Hersh et al.   Current Alzheimer Research

Valproic acid inhibits Aβ production, neuritic plaque formation, and behavioral deficits in Alzheimer's disease mouse models

(2008) Hong Qing et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Enhanced clearance of A  in brain by sustaining the plasmin proteolysis cascade

(2008) J. S. Jacobsen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Hypoxia increases Aβ generation by altering β- and γ-cleavage of APP

(2007) Liang Li et al.   NEUROBIOLOGY OF AGING