The interplay between aging‐associated loss of protein homeostasis and extracellular vesicles in neurodegeneration
Published 2019 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
The interplay between aging‐associated loss of protein homeostasis and extracellular vesicles in neurodegeneration
Authors
Keywords
-
Journal
JOURNAL OF NEUROSCIENCE RESEARCH
Volume -, Issue -, Pages -
Publisher
Wiley
Online
2019-09-24
DOI
10.1002/jnr.24526
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Ubiquilins regulate autophagic flux through mTOR signalling and lysosomal acidification
- (2019) Mümine Şentürk et al. NATURE CELL BIOLOGY
- The Major Risk Factors for Alzheimer’s Disease: Age, Sex, and Genes Modulate the Microglia Response to Aβ Plaques
- (2019) Carlo Sala Frigerio et al. Cell Reports
- Alzheimer’s disease pathology propagation by exosomes containing toxic amyloid-beta oligomers
- (2018) Maitrayee Sardar Sinha et al. ACTA NEUROPATHOLOGICA
- Apolipoprotein E4 inhibits autophagy gene products through direct, specific binding to CLEAR motifs
- (2018) Paul A. Parcon et al. Alzheimers & Dementia
- Cholesterol impairs autophagy-mediated clearance of amyloid beta while promoting its secretion
- (2018) Elisabet Barbero-Camps et al. Autophagy
- The role of glucocerebrosidase in Parkinson disease pathogenesis
- (2018) Matthew E. Gegg et al. FEBS Journal
- Detection of Aggregation-Competent Tau in Neuron-Derived Extracellular Vesicles
- (2018) Francesc Guix et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- ApoE facilitates the microglial response to amyloid plaque pathology
- (2018) Jason D. Ulrich et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Shared mechanisms among neurodegenerative diseases: from genetic factors to gene networks
- (2018) Douglas Arneson et al. JOURNAL OF GENETICS
- Deciphering the role of VPS35 in Parkinson's disease
- (2018) Erin T. Williams et al. JOURNAL OF NEUROSCIENCE RESEARCH
- Alterations in cholesterol metabolism–related genes in sporadic Alzheimer's disease
- (2018) Cynthia Picard et al. NEUROBIOLOGY OF AGING
- The olfactory bulb as the entry site for prion-like propagation in neurodegenerative diseases
- (2018) Nolwen L. Rey et al. NEUROBIOLOGY OF DISEASE
- Neuronal lysosomal dysfunction releases exosomes harboring APP C-terminal fragments and unique lipid signatures
- (2018) André M. Miranda et al. Nature Communications
- Synaptic Tau Seeding Precedes Tau Pathology in Human Alzheimer's Disease Brain
- (2018) Sarah L. DeVos et al. Frontiers in Neuroscience
- Ageing, Cellular Senescence and Neurodegenerative Disease
- (2018) Marios Kritsilis et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Proteins Recruited to Exosomes by Tau Overexpression Implicate Novel Cellular Mechanisms Linking Tau Secretion with Alzheimer's Disease
- (2018) Sudad Saman et al. JOURNAL OF ALZHEIMERS DISEASE
- A Novel p.Leu(381)Phe Mutation in Presenilin 1 is Associated with Very Early Onset and Unusually Fast Progressing Dementia as well as Lysosomal Inclusions Typically Seen in Kufs Disease
- (2018) Natalia Dolzhanskaya et al. JOURNAL OF ALZHEIMERS DISEASE
- Decreased Expression of Cathepsin D in Monocytes is Related to the Defective Degradation of Amyloid-β in Alzheimer's Disease
- (2018) Li Tian et al. JOURNAL OF ALZHEIMERS DISEASE
- Huntingtin Aggregation Impairs Autophagy, Leading to Argonaute-2 Accumulation and Global MicroRNA Dysregulation
- (2018) Karolina Pircs et al. Cell Reports
- Apolipoprotein E4 genotype compromises brain exosome production
- (2018) Katherine Y Peng et al. BRAIN
- Frontotemporal dementia causative CHMP2B impairs neuronal endolysosomal traffic-rescue by TMEM106B knockdown
- (2018) Emma L Clayton et al. BRAIN
- Secretion and Uptake of α-Synuclein Via Extracellular Vesicles in Cultured Cells
- (2018) Gabriel Gustafsson et al. CELLULAR AND MOLECULAR NEUROBIOLOGY
- Lipid‐induced lysosomal damage after demyelination corrupts microglia protective function in lysosomal storage disorders
- (2018) Enrique Gabandé‐Rodríguez et al. EMBO JOURNAL
- Altered γ-Secretase Processing of APP Disrupts Lysosome and Autophagosome Function in Monogenic Alzheimer’s Disease
- (2018) Christy O.Y. Hung et al. Cell Reports
- Amyloid precursor protein and endosomal–lysosomal dysfunction in Alzheimer’s disease: inseparable partners in a multifactorial disease
- (2017) Ralph A. Nixon FASEB JOURNAL
- Adaptor protein CD2AP and L-type lectin LMAN2 regulate exosome cargo protein trafficking through the Golgi complex.
- (2017) Sang-Ho Kwon et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Optineurin promotes autophagosome formation by recruiting the autophagy-related Atg12-5-16L1 complex to phagophores containing the Wipi2 protein
- (2017) Megha Bansal et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Impaired JIP3-dependent axonal lysosome transport promotes amyloid plaque pathology
- (2017) Swetha Gowrishankar et al. JOURNAL OF CELL BIOLOGY
- Mutant Huntingtin Inhibits αB-Crystallin Expression and Impairs Exosome Secretion from Astrocytes
- (2017) Yan Hong et al. JOURNAL OF NEUROSCIENCE
- Tetraspanin 6: a pivotal protein of the multiple vesicular body determining exosome release and lysosomal degradation of amyloid precursor protein fragments
- (2017) Francesc X. Guix et al. Molecular Neurodegeneration
- PLD3 gene and processing of APP
- (2017) Pietro Fazzari et al. NATURE
- Decreased gene expression of CD2AP in Chinese patients with sporadic Alzheimer's disease
- (2017) Qing-Qing Tao et al. NEUROBIOLOGY OF AGING
- ApoE4 Accelerates Early Seeding of Amyloid Pathology
- (2017) Chia-Chen Liu et al. NEURON
- Loss of TMEM106B Ameliorates Lysosomal and Frontotemporal Dementia-Related Phenotypes in Progranulin-Deficient Mice
- (2017) Zoe A. Klein et al. NEURON
- TMEM175 deficiency impairs lysosomal and mitochondrial function and increases α-synuclein aggregation
- (2017) Sarah Jinn et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Lipids in exosomes: Current knowledge and the way forward
- (2017) Tore Skotland et al. PROGRESS IN LIPID RESEARCH
- Dopamine oxidation mediates mitochondrial and lysosomal dysfunction in Parkinson’s disease
- (2017) Lena F. Burbulla et al. SCIENCE
- Individuals with progranulin haploinsufficiency exhibit features of neuronal ceroid lipofuscinosis
- (2017) Michael E. Ward et al. Science Translational Medicine
- Spread of tau down neural circuits precedes synapse and neuronal loss in the rTgTauEC mouse model of early Alzheimer's disease
- (2017) Eleanor K. Pickett et al. SYNAPSE
- Plasma Exosomes Spread and Cluster Around β-Amyloid Plaques in an Animal Model of Alzheimer’s Disease
- (2017) Tingting Zheng et al. Frontiers in Aging Neuroscience
- Neuropathological Staging of Brain Pathology in Sporadic Parkinson’s disease: Separating the Wheat from the Chaff
- (2017) Heiko Braak et al. Journal of Parkinsons Disease
- TBK1: a new player in ALS linking autophagy and neuroinflammation
- (2017) James A. Oakes et al. Molecular Brain
- The Endosomal–Lysosomal Pathway Is Dysregulated by APOE4 Expression in Vivo
- (2017) Tal Nuriel et al. Frontiers in Neuroscience
- Enhanced exosome secretion in Down syndrome brain - a protective mechanism to alleviate neuronal endosomal abnormalities
- (2017) Sébastien A. Gauthier et al. Acta Neuropathologica Communications
- C-terminal fragments of the amyloid precursor protein in cerebrospinal fluid as potential biomarkers for Alzheimer disease
- (2017) María-Salud García-Ayllón et al. Scientific Reports
- Intraneuronal aggregation of the β-CTF fragment of APP (C99) induces Aβ-independent lysosomal-autophagic pathology
- (2016) Inger Lauritzen et al. ACTA NEUROPATHOLOGICA
- Brain Disorders Due to Lysosomal Dysfunction
- (2016) Alessandro Fraldi et al. Annual Review of Neuroscience
- Exosome secretion is a key pathway for clearance of pathological TDP-43
- (2016) Yohei Iguchi et al. BRAIN
- UBQLN2 Mediates Autophagy-Independent Protein Aggregate Clearance by the Proteasome
- (2016) Roland Hjerpe et al. CELL
- Tunneling nanotubes spread fibrillar α‐synuclein by intercellular trafficking of lysosomes
- (2016) Saïda Abounit et al. EMBO JOURNAL
- VCP/p97 cooperates with YOD1, UBXD1 and PLAA to drive clearance of ruptured lysosomes by autophagy
- (2016) Chrisovalantis Papadopoulos et al. EMBO JOURNAL
- The amyloid hypothesis of Alzheimer's disease at 25 years
- (2016) Dennis J Selkoe et al. EMBO Molecular Medicine
- Bin1 and CD2AP polarise the endocytic generation of beta‐amyloid
- (2016) Florent Ubelmann et al. EMBO REPORTS
- Loss of Mitochondrial Function Impairs Lysosomes
- (2016) Julie Demers-Lamarche et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- The amyloid cascade hypothesis: are we poised for success or failure?
- (2016) Eric Karran et al. JOURNAL OF NEUROCHEMISTRY
- Exosomal cellular prion protein drives fibrillization of amyloid beta and counteracts amyloid beta-mediated neurotoxicity
- (2016) Clemens Falker et al. JOURNAL OF NEUROCHEMISTRY
- Genetics of FTLD: overview and what else we can expect from genetic studies
- (2016) Cyril Pottier et al. JOURNAL OF NEUROCHEMISTRY
- Parkin Modulates Endosomal Organization and Function of the Endo-Lysosomal Pathway
- (2016) Pingping Song et al. JOURNAL OF NEUROSCIENCE
- Neutral Sphingomyelinase-2 Deficiency Ameliorates Alzheimer's Disease Pathology and Improves Cognition in the 5XFAD Mouse
- (2016) Michael B. Dinkins et al. JOURNAL OF NEUROSCIENCE
- Global, regional, and national incidence, prevalence, and years lived with disability for 310 diseases and injuries, 1990–2015: a systematic analysis for the Global Burden of Disease Study 2015
- (2016) Theo Vos et al. LANCET
- Treating neurodegenerative disease before illness: a challenge for the 21st century
- (2016) Karl Kieburtz LANCET NEUROLOGY
- Defeating Alzheimer's disease and other dementias: a priority for European science and society
- (2016) Bengt Winblad et al. LANCET NEUROLOGY
- C9orf72 binds SMCR8, localizes to lysosomes, and regulates mTORC1 signaling
- (2016) Joseph Amick et al. MOLECULAR BIOLOGY OF THE CELL
- Neuronal activity enhances tau propagation and tau pathology in vivo
- (2016) Jessica W Wu et al. NATURE NEUROSCIENCE
- A critical appraisal of the pathogenic protein spread hypothesis of neurodegeneration
- (2016) Dominic M. Walsh et al. NATURE REVIEWS NEUROSCIENCE
- Partial BACE1 reduction in a Down syndrome mouse model blocks Alzheimer-related endosomal anomalies and cholinergic neurodegeneration: role of APP-CTF
- (2016) Ying Jiang et al. NEUROBIOLOGY OF AGING
- Loss of exosomes in progranulin-associated frontotemporal dementia
- (2016) Luisa Benussi et al. NEUROBIOLOGY OF AGING
- Prevalence, characteristics, and survival of frontotemporal lobar degeneration syndromes
- (2016) Ian T.S. Coyle-Gilchrist et al. NEUROLOGY
- Comparative proteomics of exosomes secreted by tumoral Jurkat T cells and normal human T cell blasts unravels a potential tumorigenic role for valosin-containing protein
- (2016) Alberto Bosque et al. Oncotarget
- Genes associated with Alzheimer's disease: an overview and current status
- (2016) Mohan Giri et al. Clinical Interventions in Aging
- The ALS/FTLD associated protein C9orf72 associates with SMCR8 and WDR41 to regulate the autophagy-lysosome pathway
- (2016) Peter M. Sullivan et al. Acta Neuropathologica Communications
- Tunneling nanotube (TNT)-mediated neuron-to neuron transfer of pathological Tau protein assemblies
- (2016) Meryem Tardivel et al. Acta Neuropathologica Communications
- Frontotemporal dementia caused by CHMP2B mutation is characterised by neuronal lysosomal storage pathology
- (2015) Emma L. Clayton et al. ACTA NEUROPATHOLOGICA
- Loss-of-function mutation in ABCA1 and risk of Alzheimer's disease and cerebrovascular disease
- (2015) Liv Tybjærg Nordestgaard et al. Alzheimers & Dementia
- Identification of preclinical Alzheimer's disease by a profile of pathogenic proteins in neurally derived blood exosomes: A case-control study
- (2015) Massimo S. Fiandaca et al. Alzheimers & Dementia
- Alzheimer’s Disease Risk Genes and Mechanisms of Disease Pathogenesis
- (2015) Celeste M. Karch et al. BIOLOGICAL PSYCHIATRY
- A TRP Channel Senses Lysosome Neutralization by Pathogens to Trigger Their Expulsion
- (2015) Yuxuan Miao et al. CELL
- The Distinct Role of ADAM17 in APP Proteolysis and Microglial Activation Related to Alzheimer’s Disease
- (2015) Meng Qian et al. CELLULAR AND MOLECULAR NEUROBIOLOGY
- p62/SQSTM1 functions as a signaling hub and an autophagy adaptor
- (2015) Yoshinori Katsuragi et al. FEBS Journal
- ATP-binding Cassette Transporter A7 (ABCA7) Loss of Function Alters Alzheimer Amyloid Processing
- (2015) Kanayo Satoh et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Brain region-dependent differential expression of alpha-synuclein
- (2015) Katsutoshi Taguchi et al. JOURNAL OF COMPARATIVE NEUROLOGY
- Qualitative changes in human γ-secretase underlie familial Alzheimer’s disease
- (2015) Maria Szaruga et al. JOURNAL OF EXPERIMENTAL MEDICINE
- C-Terminally Truncated Forms of Tau, But Not Full-Length Tau or Its C-Terminal Fragments, Are Released from Neurons Independently of Cell Death
- (2015) D. Kanmert et al. JOURNAL OF NEUROSCIENCE
- Prevention of sporadic Alzheimer's disease: lessons learned from clinical trials and future directions
- (2015) Sandrine Andrieu et al. LANCET NEUROLOGY
- Evidence that the rab5 effector APPL1 mediates APP-βCTF-induced dysfunction of endosomes in Down syndrome and Alzheimer’s disease
- (2015) S Kim et al. MOLECULAR PSYCHIATRY
- η-Secretase processing of APP inhibits neuronal activity in the hippocampus
- (2015) Michael Willem et al. NATURE
- Loss-of-function variants in ABCA7 confer risk of Alzheimer's disease
- (2015) Stacy Steinberg et al. NATURE GENETICS
- Spreading of pathology in neurodegenerative diseases: a focus on human studies
- (2015) Johannes Brettschneider et al. NATURE REVIEWS NEUROSCIENCE
- Altered lysosomal proteins in neural-derived plasma exosomes in preclinical Alzheimer disease
- (2015) Edward J. Goetzl et al. NEUROLOGY
- Massive accumulation of luminal protease-deficient axonal lysosomes at Alzheimer’s disease amyloid plaques
- (2015) Swetha Gowrishankar et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Y682G Mutation of Amyloid Precursor Protein Promotes Endo-Lysosomal Dysfunction by Disrupting APP–SorLA Interaction
- (2015) Luca Rosario La Rosa et al. Frontiers in Cellular Neuroscience
- Apolipoprotein E Regulates Amyloid Formation within Endosomes of Pigment Cells
- (2015) Guillaume van Niel et al. Cell Reports
- Neurodegenerative lysosomal disorders: A continuum from development to late age
- (2014) Ralph A. Nixon et al. Autophagy
- High sphingomyelin levels induce lysosomal damage and autophagy dysfunction in Niemann Pick disease type A
- (2014) E Gabandé-Rodríguez et al. CELL DEATH AND DIFFERENTIATION
- Retromer Binding to FAM21 and the WASH Complex Is Perturbed by the Parkinson Disease-Linked VPS35(D620N) Mutation
- (2014) Ian J. McGough et al. CURRENT BIOLOGY
- LAMP3 is involved in tamoxifen resistance in breast cancer cells through the modulation of autophagy
- (2014) Anika Nagelkerke et al. ENDOCRINE-RELATED CANCER
- The adipocyte differentiation protein APMAP is an endogenous suppressor of Aβ production in the brain
- (2014) Sebastien Mosser et al. HUMAN MOLECULAR GENETICS
- LRRK2 delays degradative receptor trafficking by impeding late endosomal budding through decreasing Rab7 activity
- (2014) Patricia Gómez-Suaga et al. HUMAN MOLECULAR GENETICS
- Acceleration of α-Synuclein Aggregation by Exosomes
- (2014) Marie Grey et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Dysregulation of lysosomal morphology by pathogenic LRRK2 is corrected by TPC2 inhibition
- (2014) L. N. Hockey et al. JOURNAL OF CELL SCIENCE
- ATP13A2/PARK9 Regulates Secretion of Exosomes and -Synuclein
- (2014) T. Tsunemi et al. JOURNAL OF NEUROSCIENCE
- VPS35 dysfunction impairs lysosomal degradation of α-synuclein and exacerbates neurotoxicity in a Drosophila model of Parkinson's disease
- (2014) Emiko Miura et al. NEUROBIOLOGY OF DISEASE
- Lysosomal alkalization and dysfunction in human fibroblasts with the Alzheimer’s disease-linked presenilin 1 A246E mutation can be reversed with cAMP
- (2014) E.E. Coffey et al. NEUROSCIENCE
- Lysosomal Sorting of Amyloid- by the SORLA Receptor Is Impaired by a Familial Alzheimer's Disease Mutation
- (2014) S. Caglayan et al. Science Translational Medicine
- The role of extracellular Tau in the spreading of neurofibrillary pathology
- (2014) Miguel Medina et al. Frontiers in Cellular Neuroscience
- Mutation in VPS35 associated with Parkinson’s disease impairs WASH complex association and inhibits autophagy
- (2014) Eszter Zavodszky et al. Nature Communications
- PICALM modulates autophagy activity and tau accumulation
- (2014) Kevin Moreau et al. Nature Communications
- Possible involvement of lysosomal dysfunction in pathological changes of the brain in aged progranulin-deficient mice
- (2014) Yoshinori Tanaka et al. Acta Neuropathologica Communications
- Making the Diagnosis of Frontotemporal Lobar Degeneration
- (2013) Eileen H. Bigio ARCHIVES OF PATHOLOGY & LABORATORY MEDICINE
- Physiological release of endogenous tau is stimulated by neuronal activity
- (2013) Amy M Pooler et al. EMBO REPORTS
- The Intracellular Interactome of Tetraspanin-enriched Microdomains Reveals Their Function as Sorting Machineries toward Exosomes
- (2013) Daniel Perez-Hernandez et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Extracellular vesicles: Exosomes, microvesicles, and friends
- (2013) Graça Raposo et al. JOURNAL OF CELL BIOLOGY
- Sorting receptor SORLA - a trafficking path to avoid Alzheimer disease
- (2013) T. E. Willnow et al. JOURNAL OF CELL SCIENCE
- Transfer of polyglutamine aggregates in neuronal cells occurs in tunneling nanotubes
- (2013) M. Costanzo et al. JOURNAL OF CELL SCIENCE
- Analysis of ESCRT functions in exosome biogenesis, composition and secretion highlights the heterogeneity of extracellular vesicles
- (2013) Marina Colombo et al. JOURNAL OF CELL SCIENCE
- Lysosomal impairment in Parkinson's disease
- (2013) Benjamin Dehay et al. MOVEMENT DISORDERS
- Rare coding variants in the phospholipase D3 gene confer risk for Alzheimer’s disease
- (2013) Carlos Cruchaga et al. NATURE
- miR128 up-regulation correlates with impaired amyloid β(1-42) degradation in monocytes from patients with sporadic Alzheimer's disease
- (2013) Roberto Tiribuzi et al. NEUROBIOLOGY OF AGING
- RAB7L1 Interacts with LRRK2 to Modify Intraneuronal Protein Sorting and Parkinson’s Disease Risk
- (2013) David A. MacLeod et al. NEURON
- Characterization of Novel CSF Tau and ptau Biomarkers for Alzheimer’s Disease
- (2013) Jere E. Meredith Jr. et al. PLoS One
- Adaptor complex AP2/PICALM, through interaction with LC3, targets Alzheimer's APP-CTF for terminal degradation via autophagy
- (2013) Y. Tian et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Exosomes neutralize synaptic-plasticity-disrupting activity of Aβ assemblies in vivo
- (2013) Kyongman An et al. Molecular Brain
- Lipofuscin: formation, effects and role of macroautophagy
- (2013) Annika Höhn et al. Redox Biology
- Distinct patterns of APP processing in the CNS in autosomal-dominant and sporadic Alzheimer disease
- (2012) Marta Pera et al. ACTA NEUROPATHOLOGICA
- Oxidative lipid modification of nicastrin enhances amyloidogenic γ-secretase activity in Alzheimer’s disease
- (2012) A-Ryeong Gwon et al. AGING CELL
- Strikingly Different Clinicopathological Phenotypes Determined by Progranulin-Mutation Dosage
- (2012) Katherine R. Smith et al. AMERICAN JOURNAL OF HUMAN GENETICS
- Ageing as a Risk Factor for Disease
- (2012) Teresa Niccoli et al. CURRENT BIOLOGY
- The mechanism of γ-Secretase dysfunction in familial Alzheimer disease
- (2012) Lucía Chávez-Gutiérrez et al. EMBO JOURNAL
- Modification of γ-secretase by nitrosative stress links neuronal ageing to sporadic Alzheimer's disease
- (2012) Francesc X. Guix et al. EMBO Molecular Medicine
- Rab7 Mutants Associated with Charcot-Marie-Tooth Disease Cause Delayed Growth Factor Receptor Transport and Altered Endosomal and Nuclear Signaling
- (2012) Soumik BasuRay et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- The immunology of neurodegeneration
- (2012) Eva Czirr et al. JOURNAL OF CLINICAL INVESTIGATION
- Deficiency of ATP13A2 Leads to Lysosomal Dysfunction, -Synuclein Accumulation, and Neurotoxicity
- (2012) M. Usenovic et al. JOURNAL OF NEUROSCIENCE
- Nerve Growth Factor and Alzheimer's Disease: New Facts for an Old Hypothesis
- (2012) Antonino Cattaneo et al. MOLECULAR NEUROBIOLOGY
- Probing sporadic and familial Alzheimer’s disease using induced pluripotent stem cells
- (2012) Mason A. Israel et al. NATURE
- Syndecan–syntenin–ALIX regulates the biogenesis of exosomes
- (2012) Maria Francesca Baietti et al. NATURE CELL BIOLOGY
- Presenilin Deficiency or Lysosomal Inhibition Enhances Wnt Signaling through Relocalization of GSK3 to the Late-Endosomal Compartment
- (2012) Radek Dobrowolski et al. Cell Reports
- SQSTM1 Mutations in Familial and Sporadic Amyotrophic Lateral Sclerosis
- (2011) Faisal Fecto ARCHIVES OF NEUROLOGY
- Role of pro-inflammatory cytokines released from microglia in neurodegenerative diseases
- (2011) Joshua A. Smith et al. BRAIN RESEARCH BULLETIN
- Frontotemporal Dementia Caused by CHMP2B Mutations
- (2011) A. M. Isaacs et al. Current Alzheimer Research
- The Tetraspanin CD63 Regulates ESCRT-Independent and -Dependent Endosomal Sorting during Melanogenesis
- (2011) Guillaume van Niel et al. DEVELOPMENTAL CELL
- The role of tetraspanin CD63 in antigen presentation via MHC class II
- (2011) Sven H. Petersen et al. EUROPEAN JOURNAL OF IMMUNOLOGY
- Exosome-associated Tau Is Secreted in Tauopathy Models and Is Selectively Phosphorylated in Cerebrospinal Fluid in Early Alzheimer Disease
- (2011) Sudad Saman et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Mutations in UBQLN2 cause dominant X-linked juvenile and adult-onset ALS and ALS/dementia
- (2011) Han-Xiang Deng et al. NATURE
- Epidemiology of Alzheimer disease
- (2011) Christiane Reitz et al. Nature Reviews Neurology
- Retromer disruption promotes amyloidogenic APP processing
- (2011) Christopher P. Sullivan et al. NEUROBIOLOGY OF DISEASE
- Autophagy failure in Alzheimer's disease—locating the primary defect
- (2011) Ralph A. Nixon et al. NEUROBIOLOGY OF DISEASE
- Lysosomal dysfunction increases exosome-mediated alpha-synuclein release and transmission
- (2011) Lydia Alvarez-Erviti et al. NEUROBIOLOGY OF DISEASE
- Multivesicular bodies in neurons: Distribution, protein content, and trafficking functions
- (2011) Christopher S. Von Bartheld et al. PROGRESS IN NEUROBIOLOGY
- Alzheimer's Disease: The Challenge of the Second Century
- (2011) D. M. Holtzman et al. Science Translational Medicine
- Human apoE Isoforms Differentially Regulate Brain Amyloid- Peptide Clearance
- (2011) J. M. Castellano et al. Science Translational Medicine
- Chaperone-Mediated Autophagy Markers in Parkinson Disease Brains
- (2010) Lydia Alvarez-Erviti et al. ARCHIVES OF NEUROLOGY
- VCP/p97 is essential for maturation of ubiquitin-containing autophagosomes and this function is impaired by mutations that cause IBMPFD
- (2010) Emilie Tresse et al. Autophagy
- Lysosomal Proteolysis and Autophagy Require Presenilin 1 and Are Disrupted by Alzheimer-Related PS1 Mutations
- (2010) Ju-Hyun Lee et al. CELL
- ADAM10 is the physiologically relevant, constitutive α-secretase of the amyloid precursor protein in primary neurons
- (2010) Peer-Hendrik Kuhn et al. EMBO JOURNAL
- The melanoma-associated transmembrane glycoprotein Gpnmb controls trafficking of cellular debris for degradation and is essential for tissue repair
- (2010) Bing Li et al. FASEB JOURNAL
- Cathepsin D is one of the major enzymes involved in intracellular degradation of AGE-modified proteins
- (2010) Stefanie Grimm et al. FREE RADICAL RESEARCH
- Disruption of endocytic trafficking in frontotemporal dementia with CHMP2B mutations
- (2010) Hazel Urwin et al. HUMAN MOLECULAR GENETICS
- DJ-1 acts in parallel to the PINK1/parkin pathway to control mitochondrial function and autophagy
- (2010) Kelly Jean Thomas et al. HUMAN MOLECULAR GENETICS
- Exosome Secretion Ameliorates Lysosomal Storage of Cholesterol in Niemann-Pick Type C Disease
- (2010) Katrin Strauss et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Macroautophagy Is Not Directly Involved in the Metabolism of Amyloid Precursor Protein
- (2010) Barry Boland et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Review Article: Genetics of Alzheimer Disease
- (2010) Lynn M. Bekris et al. JOURNAL OF GERIATRIC PSYCHIATRY AND NEUROLOGY
- The Disintegrin/Metalloproteinase ADAM10 Is Essential for the Establishment of the Brain Cortex
- (2010) E. Jorissen et al. JOURNAL OF NEUROSCIENCE
- Pathogenic Lysosomal Depletion in Parkinson's Disease
- (2010) B. Dehay et al. JOURNAL OF NEUROSCIENCE
- Mutations of optineurin in amyotrophic lateral sclerosis
- (2010) Hirofumi Maruyama et al. NATURE
- Membrane budding and scission by the ESCRT machinery: it's all in the neck
- (2010) James H. Hurley et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Integration of Clearance Mechanisms: The Proteasome and Autophagy
- (2010) E. Wong et al. Cold Spring Harbor Perspectives in Biology
- Getting a Grip on Prions: Oligomers, Amyloids, and Pathological Membrane Interactions
- (2009) Byron Caughey et al. Annual Review of Biochemistry
- Acid sphingomyelinase activity triggers microparticle release from glial cells
- (2009) Fabio Bianco et al. EMBO JOURNAL
- Quantitative analysis of multivesicular bodies (MVBs) in the hypoglossal nerve: Evidence that neurotrophic factors do not use MVBs for retrograde axonal transport
- (2009) Amy L. Altick et al. JOURNAL OF COMPARATIVE NEUROLOGY
- Expression of SORL1 and a novel SORL1 splice variant in normal and Alzheimers disease brain
- (2009) Karrie E Grear et al. Molecular Neurodegeneration
- Alterations in lysosomal and proteasomal markers in Parkinson's disease: Relationship to alpha-synuclein inclusions
- (2009) Yaping Chu et al. NEUROBIOLOGY OF DISEASE
- Multicenter Analysis of Glucocerebrosidase Mutations in Parkinson's Disease
- (2009) E. Sidransky et al. NEW ENGLAND JOURNAL OF MEDICINE
- Abberant α-Synuclein Confers Toxicity to Neurons in Part through Inhibition of Chaperone-Mediated Autophagy
- (2009) Maria Xilouri et al. PLoS One
- The proteasome: Overview of structure and functions
- (2009) Keiji TANAKA PROCEEDINGS OF THE JAPAN ACADEMY SERIES B-PHYSICAL AND BIOLOGICAL SCIENCES
- Alzheimer's-related endosome dysfunction in Down syndrome is A -independent but requires APP and is reversed by BACE-1 inhibition
- (2009) Y. Jiang et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- MHC II in Dendritic Cells is Targeted to Lysosomes or T Cell-Induced Exosomes Via Distinct Multivesicular Body Pathways
- (2009) Sonja I. Buschow et al. TRAFFIC
- Down Syndrome Fibroblast Model of Alzheimer-Related Endosome Pathology
- (2008) Anne M. Cataldo et al. AMERICAN JOURNAL OF PATHOLOGY
- LRRK2 regulates synaptic vesicle endocytosis
- (2008) Narae Shin et al. EXPERIMENTAL CELL RESEARCH
- Inhibition of γ-secretase causes increased secretion of amyloid precursor protein C-terminal fragments in association with exosomes
- (2008) Robyn A. Sharples et al. FASEB JOURNAL
- Tau deletion exacerbates the phenotype of Niemann–Pick type C mice and implicates autophagy in pathogenesis
- (2008) Chris D. Pacheco et al. HUMAN MOLECULAR GENETICS
- Gaucher disease: mutation and polymorphism spectrum in the glucocerebrosidase gene (GBA)
- (2008) Kathleen S. Hruska et al. HUMAN MUTATION
- Direct and Potent Regulation of γ-Secretase by Its Lipid Microenvironment
- (2008) Pamela Osenkowski et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Rab5 modulates aggregation and toxicity of mutant huntingtin through macroautophagy in cell and fly models of Huntington disease
- (2008) B. Ravikumar et al. JOURNAL OF CELL SCIENCE
- The Niemann-Pick C1 gene is downregulated by feedback inhibition of the SREBP pathway in human fibroblasts
- (2008) William S. Garver et al. JOURNAL OF LIPID RESEARCH
- The Chaperone-Mediated Autophagy Receptor Organizes in Dynamic Protein Complexes at the Lysosomal Membrane
- (2008) U. Bandyopadhyay et al. MOLECULAR AND CELLULAR BIOLOGY
- Ceramide Triggers Budding of Exosome Vesicles into Multivesicular Endosomes
- (2008) K. Trajkovic et al. SCIENCE
- Autophagy and aging: keeping that old broom working
- (2008) Ana Maria Cuervo TRENDS IN GENETICS
Find the ideal target journal for your manuscript
Explore over 38,000 international journals covering a vast array of academic fields.
SearchBecome a Peeref-certified reviewer
The Peeref Institute provides free reviewer training that teaches the core competencies of the academic peer review process.
Get Started