Partial BACE1 reduction in a Down syndrome mouse model blocks Alzheimer-related endosomal anomalies and cholinergic neurodegeneration: role of APP-CTF

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Title
Partial BACE1 reduction in a Down syndrome mouse model blocks Alzheimer-related endosomal anomalies and cholinergic neurodegeneration: role of APP-CTF
Authors
Keywords
Trisomic mice, BACE1, APP-βCTF, Alzheimer's disease, Endosomes, Basal forebrain cholinergic neurons
Journal
NEUROBIOLOGY OF AGING
Volume 39, Issue -, Pages 90-98
Publisher
Elsevier BV
Online
2015-12-02
DOI
10.1016/j.neurobiolaging.2015.11.013

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