SILAC-Based Quantification of TGFBR2-Regulated Protein Expression in Extracellular Vesicles of Microsatellite Unstable Colorectal Cancers

Ticket to a bubble ride: Cargo sorting into exosomes and extracellular vesicles

(2019) Sushma Anand et al.   BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS

Transforming Growth Factor-β Signaling in Immunity and Cancer

(2019) Eduard Batlle et al.   IMMUNITY

Exosomes and extracellular vesicles: the path forward

(2018) Philip D. Stahl et al.   Essays in Biochemistry

Down-regulation of FN1 inhibits colorectal carcinogenesis by suppressing proliferation, migration, and invasion

(2018) Xun Cai et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Shedding light on the cell biology of extracellular vesicles

(2018) Guillaume van Niel et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

A Role for p53 in the Adaptation to Glutamine Starvation through the Expression of SLC1A3

(2018) Mylène Tajan et al.   Cell Metabolism

Extracellular histones are the ligands for the uptake of exosomes and hydroxyapatite-nanoparticles by tumor cells via syndecan-4

(2018) Josiah Ochieng et al.   FEBS LETTERS

Specificities of secretion and uptake of exosomes and other extracellular vesicles for cell-to-cell communication

(2018) Mathilde Mathieu et al.   NATURE CELL BIOLOGY

Vesiclepedia 2019: a compendium of RNA, proteins, lipids and metabolites in extracellular vesicles

(2018) Mohashin Pathan et al.   NUCLEIC ACIDS RESEARCH

The PRIDE database and related tools and resources in 2019: improving support for quantification data

(2018) Yasset Perez-Riverol et al.   NUCLEIC ACIDS RESEARCH

STRING v11: protein–protein association networks with increased coverage, supporting functional discovery in genome-wide experimental datasets

(2018) Damian Szklarczyk et al.   NUCLEIC ACIDS RESEARCH

Proteomic Analysis of Extracellular Vesicles for Cancer Diagnostics

(2018) Anthony Yan-Tang Wu et al.   PROTEOMICS

The Dynamics of TGF-β Signaling Are Dictated by Receptor Trafficking via the ESCRT Machinery

(2018) Daniel S.J. Miller et al.   Cell Reports

First FDA Approval Agnostic of Cancer Site — When a Biomarker Defines the Indication

(2017) Steven Lemery et al.   NEW ENGLAND JOURNAL OF MEDICINE

Mismatch repair deficiency predicts response of solid tumors to PD-1 blockade

(2017) Dung T. Le et al.   SCIENCE

Extracellular Vesicles in Cancer: Cell-to-Cell Mediators of Metastasis

(2016) Annette Becker et al.   CANCER CELL

Transcriptional activation of FN1 and IL11 by HMGA2 promotes the malignant behavior of colorectal cancer

(2016) Jingjing Wu et al.   CARCINOGENESIS

Protein content and functional characteristics of serum-purified exosomes from patients with colorectal cancer revealed by quantitative proteomics

(2016) Yanyu Chen et al.   INTERNATIONAL JOURNAL OF CANCER

The Perseus computational platform for comprehensive analysis of (prote)omics data

(2016) Stefka Tyanova et al.   NATURE METHODS

The MaxQuant computational platform for mass spectrometry-based shotgun proteomics

(2016) Stefka Tyanova et al.   Nature Protocols

The ProteomeXchange consortium in 2017: supporting the cultural change in proteomics public data deposition

(2016) Eric W. Deutsch et al.   NUCLEIC ACIDS RESEARCH

Mismatch Repair and Colon Cancer: Mechanisms and Therapies Explored

(2016) Stephen K.H. Li et al.   TRENDS IN MOLECULAR MEDICINE

Comparative proteomics of exosomes secreted by tumoral Jurkat T cells and normal human T cell blasts unravels a potential tumorigenic role for valosin-containing protein

(2016) Alberto Bosque et al.   Oncotarget

Fibronectin on circulating extracellular vesicles as a liquid biopsy to detect breast cancer

(2016) Pyong-Gon Moon et al.   Oncotarget

Tumor microenvironment derived exosomes pleiotropically modulate cancer cell metabolism

(2016) Hongyun Zhao et al.   eLife

Cell surface receptors for CCN proteins

(2016) Lester F. Lau   Journal of Cell Communication and Signaling

Fibronectin on the Surface of Myeloma Cell-derived Exosomes Mediates Exosome-Cell Interactions

(2015) Anurag Purushothaman et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Glutamine synthetase activity fuels nucleotide biosynthesis and supports growth of glutamine-restricted glioblastoma

(2015) Saverio Tardito et al.   NATURE CELL BIOLOGY

Myeloid-specific TGF-β signaling in bone promotes basic-FGF and breast cancer bone metastasis

(2015) X Meng et al.   ONCOGENE

Directional cell movement through tissues is controlled by exosome secretion

(2015) Bong Hwan Sung et al.   Nature Communications

Activation of Pro-uPA Is Critical for Initial Escape from the Primary Tumor and Hematogenous Dissemination of Human Carcinoma Cells

(2015) Erin M. Bekes et al.   NEOPLASIA

Ubiquitinated Proteins in Exosomes Secreted by Myeloid-Derived Suppressor Cells

(2014) Meghan C. Burke et al.   JOURNAL OF PROTEOME RESEARCH

A single nucleotide polymorphism in fibronectin 1 determines tumor shape in colorectal cancer

(2014) HIROYUKI KIDA et al.   ONCOLOGY REPORTS

Transforming Growth Factor-Beta Signaling Leads to uPA/PAI-1 Activation and Metastasis: A Study on Human Breast Cancer Tissues

(2014) D. S. Lang et al.   PATHOLOGY & ONCOLOGY RESEARCH

Exosomes mediate intercellular transfer of pro-fibrogenic connective tissue growth factor (CCN2) between hepatic stellate cells, the principal fibrotic cells in the liver

(2014) Alyssa Charrier et al.   SURGERY

Tumour cells down-regulate CCN2 gene expression in co-cultured fibroblasts in a Smad7- and ERK-dependent manner

(2013) Beverley A van Rooyen et al.   Cell Communication and Signaling

Chemotherapy of MMR-deficient colorectal cancer

(2013) N. Devaud et al.   Familial Cancer

Analysis of ESCRT functions in exosome biogenesis, composition and secretion highlights the heterogeneity of extracellular vesicles

(2013) Marina Colombo et al.   JOURNAL OF CELL SCIENCE

Clinical significance of microsatellite instability in colorectal cancer

(2013) Matthias Kloor et al.   LANGENBECKS ARCHIVES OF SURGERY

Transforming Growth Factor Beta Receptor 2 (TGFBR2) Changes Sialylation in the Microsatellite Unstable (MSI) Colorectal Cancer Cell Line HCT116

(2013) Jennifer Lee et al.   PLoS One

Proteome Profiling of Neuroblastoma-Derived Exosomes Reveal the Expression of Proteins Potentially Involved in Tumor Progression

(2013) Danilo Marimpietri et al.   PLoS One

Thomas Letzel: Protein and peptide analysis by LC–MS: experimental strategies

(2012) Simone König   ANALYTICAL AND BIOANALYTICAL CHEMISTRY

Comparison of ultracentrifugation, density gradient separation, and immunoaffinity capture methods for isolating human colon cancer cell line LIM1863-derived exosomes

(2012) Bow J. Tauro et al.   METHODS

TGFβ signalling in context

(2012) Joan Massagué   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Tumor Cell Cross Talk with Tumor-Associated Leukocytes Leads to Induction of Tumor Exosomal Fibronectin and Promotes Tumor Progression

(2011) ZhongBin Deng et al.   AMERICAN JOURNAL OF PATHOLOGY

Human Trophoblast-Derived Exosomal Fibronectin Induces Pro-Inflammatory Il-1β Production by Macrophages

(2011) Safinur Atay et al.   AMERICAN JOURNAL OF REPRODUCTIVE IMMUNOLOGY

Preventing arginine-to-proline conversion in a cell-line-independent manner during cell cultivation under stable isotope labeling by amino acids in cell culture (SILAC) conditions

(2011) Christopher Lößner et al.   ANALYTICAL BIOCHEMISTRY

Andromeda: A Peptide Search Engine Integrated into the MaxQuant Environment

(2011) Jürgen Cox et al.   JOURNAL OF PROTEOME RESEARCH

Ubiquitination of α5β1 Integrin Controls Fibroblast Migration through Lysosomal Degradation of Fibronectin-Integrin Complexes

(2010) Viola Hélène Lobert et al.   DEVELOPMENTAL CELL

Microsatellite Instability in Colorectal Cancer

(2010) C. Richard Boland et al.   GASTROENTEROLOGY

Connective tissue growth factor (CTGF, CCN2) gene regulation: a potent clinical bio-marker of fibroproliferative disease?

(2009) Andrew Leask et al.   Journal of Cell Communication and Signaling

TGFβ in Cancer

(2008) Joan Massagué   CELL

The Biology of Cancer: Metabolic Reprogramming Fuels Cell Growth and Proliferation

(2008) Ralph J. DeBerardinis et al.   Cell Metabolism

MaxQuant enables high peptide identification rates, individualized p.p.b.-range mass accuracies and proteome-wide protein quantification

(2008) Jürgen Cox et al.   NATURE BIOTECHNOLOGY

Prostate tumor progression is mediated by a paracrine TGF-β/Wnt3a signaling axis

(2008) X Li et al.   ONCOGENE

Sample prep for proteomics of breast cancer: proteomics and gene ontology reveal dramatic differences in protein solubilization preferences of radioimmunoprecipitation assay and urea lysis buffers

(2008) Lambert C. M. Ngoka   Proteome Science