Transcriptional activation of FN1 and IL11 by HMGA2 promotes the malignant behavior of colorectal cancer

Cancer statistics, 2015

(2015) Rebecca L. Siegel et al.   CA-A CANCER JOURNAL FOR CLINICIANS

The challenge of targeting metastasis

(2015) Isaiah J. Fidler et al.   CANCER AND METASTASIS REVIEWS

Lin28B/Let-7 Regulates Expression of Oct4 and Sox2 and Reprograms Oral Squamous Cell Carcinoma Cells to a Stem-like State

(2015) C.-S. Chien et al.   CANCER RESEARCH

High mobility group protein-mediated transcription requires DNA damage marker γ-H2AX

(2015) Indrabahadur Singh et al.   CELL RESEARCH

Colorectal cancer screening: a global overview of existing programmes

(2015) Eline H Schreuders et al.   GUT

Detection of high mobility group A2 specific mRNA in the plasma of patients affected by epithelial ovarian cancer

(2015) Francesca Galdiero et al.   Oncotarget

Targeting IL-11 signaling in colon cancer

(2015) Matthias Ernst et al.   Oncotarget

HMGA2 induces transcription factor Slug expression to promote epithelial-to-mesenchymal transition and contributes to colon cancer progression

(2014) Yang Li et al.   CANCER LETTERS

Frequent Overexpression ofHMGA2in Human Atypical Teratoid/Rhabdoid Tumor and Its Correlation withlet-7a3/let-7bmiRNA

(2014) Keqiang Zhang et al.   CLINICAL CANCER RESEARCH

Molecular Pathways: IL11 as a Tumor-Promoting Cytokine--Translational Implications for Cancers

(2014) M. Ernst et al.   CLINICAL CANCER RESEARCH

MUC1-C Induces the LIN28B→LET-7→HMGA2 Axis to Regulate Self-Renewal in NSCLC

(2014) Maroof Alam et al.   MOLECULAR CANCER RESEARCH

Anti-miR182 Reduces Ovarian Cancer Burden, Invasion, and Metastasis: An In Vivo Study in Orthotopic Xenografts of Nude Mice

(2014) X. Xu et al.   MOLECULAR CANCER THERAPEUTICS

BET Bromodomain Inhibitors Block Growth of Pancreatic Cancer Cells in Three-Dimensional Collagen

(2014) V. Sahai et al.   MOLECULAR CANCER THERAPEUTICS

The high mobility group A2 protein epigenetically silences the Cdh1 gene during epithelial-to-mesenchymal transition

(2014) E-Jean Tan et al.   NUCLEIC ACIDS RESEARCH

Epithelial gp130/Stat3 functions: An intestinal signaling node in health and disease

(2014) Matthias Ernst et al.   SEMINARS IN IMMUNOLOGY

Interleukin-11 Is the Dominant IL-6 Family Cytokine during Gastrointestinal Tumorigenesis and Can Be Targeted Therapeutically

(2013) Tracy L. Putoczki et al.   CANCER CELL

Oncogenic NRAS, Required for Pathogenesis of Embryonic Rhabdomyosarcoma, Relies upon the HMGA2-IGF2BP2 Pathway

(2013) Z. Li et al.   CANCER RESEARCH

HMGA2 Is a Driver of Tumor Metastasis

(2013) A. Morishita et al.   CANCER RESEARCH

Epithelial to Mesenchymal Transition Promotes Breast Cancer Progression via a Fibronectin-dependent STAT3 Signaling Pathway

(2013) Nikolas Balanis et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Autocrine production of IL-11 mediates tumorigenicity in hypoxic cancer cells

(2013) Barbara Onnis et al.   JOURNAL OF CLINICAL INVESTIGATION

HMGA2 and high-grade serous ovarian carcinoma

(2013) Jingjing Wu et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

Bone metastasis from breast cancer involves elevated IL-11 expression and the gp130/STAT3 pathway

(2013) Li Ren et al.   MEDICAL ONCOLOGY

The Lin28b–let-7–Hmga2 axis determines the higher self-renewal potential of fetal haematopoietic stem cells

(2013) Michael R. Copley et al.   NATURE CELL BIOLOGY

RKIP and HMGA2 regulate breast tumor survival and metastasis through lysyl oxidase and syndecan-2

(2013) M Sun et al.   ONCOGENE

HMGA2/TET1/HOXA9 signaling pathway regulates breast cancer growth and metastasis

(2013) M. Sun et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

MicroRNA-30c inhibits human breast tumour chemotherapy resistance by regulating TWF1 and IL-11

(2013) Jessica Bockhorn et al.   Nature Communications

HMGA2 Elicits EMT by Activating the Wnt/β-catenin Pathway in Gastric Cancer

(2012) Lang Zha et al.   DIGESTIVE DISEASES AND SCIENCES

Regulation of Transcription Factor Twist Expression by the DNA Architectural Protein High Mobility Group A2 during Epithelial-to-Mesenchymal Transition

(2012) E-Jean Tan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Interleukin-11 Increases Cell Motility and Up-Regulates Intercellular Adhesion Molecule-1 Expression in Human Chondrosarcoma Cells

(2012) Te-Mao Li et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Fibronectin 1 is a potential biomarker for radioresistance in head and neck squamous cell carcinoma

(2011) Fredrik Jerhammar et al.   CANCER BIOLOGY & THERAPY

HMGA2Overexpression-Induced Ovarian Surface Epithelial Transformation Is Mediated Through Regulation of EMT Genes

(2011) Jingjing Wu et al.   CANCER RESEARCH

Overexpression of HMGA2 Promotes Metastasis and Impacts Survival of Colorectal Cancers

(2011) X. Wang et al.   CLINICAL CANCER RESEARCH

Suppression of lung adenocarcinoma progression by Nkx2-1

(2011) Monte M. Winslow et al.   NATURE

Fibronectin 1 mRNA expression correlates with advanced disease in renal cancer

(2010) Sandra Waalkes et al.   BMC CANCER

Hmga2 Promotes Neural Stem Cell Self-Renewal in Young but Not Old Mice by Reducing p16Ink4a and p19Arf Expression

(2008) Jinsuke Nishino et al.   CELL

HMGA2, MicroRNAs, and Stem Cell Aging

(2008) Scott M. Hammond et al.   CELL

HMGA2 and Smads Co-regulate SNAIL1 Expression during Induction of Epithelial-to-Mesenchymal Transition

(2008) Sylvie Thuault et al.   JOURNAL OF BIOLOGICAL CHEMISTRY