Transforming Growth Factor-Beta Signaling Leads to uPA/PAI-1 Activation and Metastasis: A Study on Human Breast Cancer Tissues

uPA and PAI-1-Related Signaling Pathways Differ between Primary Breast Cancers and Lymph Node Metastases

(2014) Katharina Malinowsky et al.   Translational Oncology

Synergistic and Multidimensional Regulation of Plasminogen Activator Inhibitor Type 1 Expression by Transforming Growth Factor Type β and Epidermal Growth Factor

(2012) Xiaoling Song et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Biological Responses to TGF-  in the Mammary Epithelium Show a Complex Dependency on Smad3 Gene Dosage with Important Implications for Tumor Progression

(2012) E. A. Kohn et al.   MOLECULAR CANCER RESEARCH

TGF-  blockade improves the distribution and efficacy of therapeutics in breast carcinoma by normalizing the tumor stroma

(2012) J. Liu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Estrogen and antiestrogens alter breast cancer invasiveness by modulating the transforming growth factor-β signaling pathway

(2011) Natsuka Goto et al.   CANCER SCIENCE

SMAD3 is essential for transforming growth factor-β1-induced urokinase type plasminogen activator expression and migration in transformed keratinocytes

(2011) Jelena Kocic et al.   EUROPEAN JOURNAL OF CANCER

HOPE-BAL

(2011) Sebastian Marwitz et al.   JOURNAL OF HISTOCHEMISTRY & CYTOCHEMISTRY

Cell Signaling by Urokinase-type Plasminogen Activator Receptor Induces Stem Cell-like Properties in Breast Cancer Cells

(2010) M. Jo et al.   CANCER RESEARCH

UPA and PAI-1 Analysis from Fixed Tissues – New Perspectives for a Known Set of Predictive Markers

(2010) K. Malinowsky et al.   CURRENT MEDICINAL CHEMISTRY

Estrogen Inhibits Transforming Growth Factor β Signaling by Promoting Smad2/3 Degradation

(2010) Ichiaki Ito et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Signalling networks associated with urokinase-type plasminogen activator (uPA) and its inhibitor PAI-1 in breast cancer tissues: new insights from protein microarray analysis

(2010) Claudia Wolff et al.   JOURNAL OF PATHOLOGY

ROS-NFκΒ mediates TGF-β1-induced expression of urokinase-type plasminogen activator, matrix metalloproteinase-9 and cell invasion

(2010) Nicolas Tobar et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

Targeting the Transforming Growth Factor-β pathway inhibits human basal-like breast cancer metastasis

(2010) Vidya Ganapathy et al.   Molecular Cancer

BAMBIgene is epigenetically silenced in subset of high-grade bladder cancer

(2009) Sann Sanda Khin et al.   INTERNATIONAL JOURNAL OF CANCER

TKTL1 is overexpressed in a large portion of non-small cell lung cancer specimens

(2008) Holger Schultz et al.   Diagnostic Pathology