Quantitative assessment of telomerase components in cancer cell lines

Rho protein GTPases and their interactions with NFκB: crossroads of inflammation and matrix biology

(2014) Louis Tong et al.   BIOSCIENCE REPORTS

Noncanonical Functions of Telomerase: Implications in Telomerase-Targeted Cancer Therapies

(2014) Yinghui Li et al.   CANCER RESEARCH

The novel vaccine peptide GV1001 effectively blocks β-amyloid toxicity by mimicking the extra-telomeric functions of human telomerase reverse transcriptase

(2014) Hyun-Hee Park et al.   NEUROBIOLOGY OF AGING

Inventory of telomerase components in human cells reveals multiple subpopulations of hTR and hTERT

(2014) Linghe Xi et al.   NUCLEIC ACIDS RESEARCH

TERT promoter mutations in primary and secondary glioblastomas

(2013) Naosuke Nonoguchi et al.   ACTA NEUROPATHOLOGICA

Human telomerase reverse transcriptase regulates MMP expression independently of telomerase activity via NF-κB-dependent transcription

(2013) Deqiang Ding et al.   FASEB JOURNAL

Genome engineering using the CRISPR-Cas9 system

(2013) F Ann Ran et al.   Nature Protocols

Structure of active dimeric human telomerase

(2013) Anselm Sauerwald et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Mitochondrial Telomerase Protects Cancer Cells from Nuclear DNA Damage and Apoptosis

(2013) Chatchawan Singhapol et al.   PLoS One

Hedgehog Signaling Regulates Telomerase Reverse Transcriptase in Human Cancer Cells

(2013) Tapati Mazumdar et al.   PLoS One

TERT promoter mutations occur frequently in gliomas and a subset of tumors derived from cells with low rates of self-renewal

(2013) P. J. Killela et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Telomerase: central regulator of all of the hallmarks of cancer

(2013) Kee Chung Low et al.   TRENDS IN BIOCHEMICAL SCIENCES

Chronic adipose tissue inflammation: all immune cells on the stage

(2013) Gökhan Cildir et al.   TRENDS IN MOLECULAR MEDICINE

Celastrol Suppresses Growth and Induces Apoptosis of Human Hepatocellular Carcinoma through the Modulation of STAT3/JAK2 Signaling Cascade In Vitro and In Vivo

(2012) P. Rajendran et al.   Cancer Prevention Research

Alternatively Spliced Telomerase Reverse Transcriptase Variants Lacking Telomerase Activity Stimulate Cell Proliferation

(2012) R. Hrdlickova et al.   MOLECULAR AND CELLULAR BIOLOGY

Telomerase Recruitment Requires both TCAB1 and Cajal Bodies Independently

(2012) J. L. Stern et al.   MOLECULAR AND CELLULAR BIOLOGY

Telomerase directly regulates NF-κB-dependent transcription

(2012) Arkasubhra Ghosh et al.   NATURE CELL BIOLOGY

Global quantification of mammalian gene expression control

(2011) Björn Schwanhäusser et al.   NATURE

Separation of telomerase functions by reverse genetics

(2011) S. Mukherjee et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Novel Dyskerin-Mediated Mechanism of p53 Inactivation through Defective mRNA Translation

(2010) Lorenzo Montanaro et al.   CANCER RESEARCH

Hexamethylene Bisacetamide (HMBA) simultaneously targets AKT and MAPK pathway and represses NF-κB activity: Implications for cancer therapy

(2010) Anwesha Dey et al.   CELL CYCLE

Telomeres and inflammation: Rap1 joins the ends?

(2010) Arka Subhra Ghosh et al.   CELL CYCLE

Telomere-independent Rap1 is an IKK adaptor and regulates NF-κB-dependent gene expression

(2010) Hsiangling Teo et al.   NATURE CELL BIOLOGY

RVB1/RVB2: Running Rings around Molecular Biology

(2009) Sudhakar Jha et al.   MOLECULAR CELL

Telomerase modulates Wnt signalling by association with target gene chromatin

(2009) Jae-Il Park et al.   NATURE

An RNA-dependent RNA polymerase formed by TERT and the RMRP RNA

(2009) Yoshiko Maida et al.   NATURE

Pontin and Reptin, Two Related ATPases with Multiple Roles in Cancer

(2008) O. Huber et al.   CANCER RESEARCH

Identification of ATPases Pontin and Reptin as Telomerase Components Essential for Holoenzyme Assembly

(2008) Andrew S. Venteicher et al.   CELL

TERT promotes cellular and organismal survival independently of telomerase activity

(2008) J Lee et al.   ONCOGENE

Mutations in the telomerase component NHP2 cause the premature ageing syndrome dyskeratosis congenita

(2008) T. Vulliamy et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Architecture of the Pontin/Reptin Complex, Essential in the Assembly of Several Macromolecular Complexes

(2008) Eva Torreira et al.   STRUCTURE