ApiAP2 Transcription Factors in Apicomplexan Parasites

Chromatin Accessibility-Based Characterization of the Gene Regulatory Network Underlying Plasmodium falciparum Blood-Stage Development

(2018) Christa Geeke Toenhake et al.   Cell Host & Microbe

In Vitro Culture, Drug Sensitivity, and Transcriptome of Plasmodium Vivax Hypnozoites

(2018) Nil Gural et al.   Cell Host & Microbe

RNA-Seq analysis during the life cycle of Cryptosporidium parvum reveals significant differential gene expression between proliferating stages in the intestine and infectious sporozoites

(2018) Christoph Lippuner et al.   INTERNATIONAL JOURNAL FOR PARASITOLOGY

Cooperative binding of ApiAP2 transcription factors is crucial for the expression of virulence genes in Toxoplasma gondii

(2018) Kevin M Lesage et al.   NUCLEIC ACIDS RESEARCH

Characterization of the accessible genome in the human malaria parasite Plasmodium falciparum

(2018) José Luis Ruiz et al.   NUCLEIC ACIDS RESEARCH

Transcriptome analysis of pig intestinal cell monolayers infected with Cryptosporidium parvum asexual stages

(2018) Marzieh Ezzaty Mirhashemi et al.   Parasites & Vectors

GDV1 induces sexual commitment of malaria parasites by antagonizing HP1-dependent gene silencing

(2018) Michael Filarsky et al.   SCIENCE

Uncovering the essential genes of the human malaria parasitePlasmodium falciparumby saturation mutagenesis

(2018) Min Zhang et al.   SCIENCE

Changes in genome organization of parasite-specific gene families during the Plasmodium transmission stages

(2018) Evelien M. Bunnik et al.   Nature Communications

Genome-wide real-time in vivo transcriptional dynamics during Plasmodium falciparum blood-stage development

(2018) Heather J. Painter et al.   Nature Communications

A Specific PfEMP1 Is Expressed in P. falciparum Sporozoites and Plays a Role in Hepatocyte Infection

(2018) Gigliola Zanghì et al.   Cell Reports

Transcriptional repression by ApiAP2 factors is central to chronic toxoplasmosis

(2018) Joshua B. Radke et al.   PLoS Pathogens

Morbidity, mortality, and long-term consequences associated with diarrhoea from Cryptosporidium infection in children younger than 5 years: a meta-analyses study

(2018) Ibrahim A Khalil et al.   Lancet Global Health

A synthetic promoter for multi-stage expression to probe complementary functions of Plasmodium adhesins

(2018) Dennis Klug et al.   JOURNAL OF CELL SCIENCE

Inducible developmental reprogramming redefines commitment to sexual development in the malaria parasite Plasmodium berghei

(2018) Robyn S. Kent et al.   Nature Microbiology

Inducing controlled cell cycle arrest and re-entry during asexual proliferation of Plasmodium falciparum malaria parasites

(2018) Riëtte van Biljon et al.   Scientific Reports

Drug Resistance in Toxoplasma gondii

(2018) Mahbobeh Montazeri et al.   Frontiers in Microbiology

Revisiting the initial steps of sexual development in the malaria parasite Plasmodium falciparum

(2018) Cristina Bancells et al.   Nature Microbiology

Capturing in vivo RNA transcriptional dynamics from the malaria parasite Plasmodium falciparum

(2017) Heather J. Painter et al.   GENOME RESEARCH

Single-cell RNA sequencing reveals a signature of sexual commitment in malaria parasites

(2017) Asaf Poran et al.   NATURE

Systematic CRISPR-Cas9-Mediated Modifications of Plasmodium yoelii ApiAP2 Genes Reveal Functional Insights into Parasite Development

(2017) Cui Zhang et al.   mBio

A disrupted transsulphuration pathway results in accumulation of redox metabolites and induction of gametocytogenesis in malaria

(2017) Divya Beri et al.   Scientific Reports

Epigenetic regulation of Plasmodium falciparum clonally variant gene expression during development in Anopheles gambiae

(2017) Elena Gómez-Díaz et al.   Scientific Reports

Culture adaptation of malaria parasites selects for convergent loss-of-function mutants

(2017) Antoine Claessens et al.   Scientific Reports

Antimalarial Drug Resistance: A Threat to Malaria Elimination

(2017) Didier Menard et al.   Cold Spring Harbor Perspectives in Medicine

A comparative transcriptomic analysis of replicating and dormant liver stages of the relapsing malaria parasite Plasmodium cynomolgi

(2017) Annemarie Voorberg-van der Wel et al.   eLife

Opposing Transcriptional Mechanisms Regulate Toxoplasma Development

(2017) Dong-Pyo Hong et al.   mSphere

Toxoplasma gondii AP2IX-4 Regulates Gene Expression during Bradyzoite Development

(2017) Sherri Huang et al.   mSphere

Adaptation of Plasmodium falciparum to its transmission environment

(2017) Martin K. Rono et al.   Nature Ecology & Evolution

An ApiAP2 member regulates expression of clonally variant genes of the human malaria parasite Plasmodium falciparum

(2017) Rafael M. Martins et al.   Scientific Reports

The development of malaria parasites in the mosquito midgut

(2016) Sandra Bennink et al.   CELLULAR MICROBIOLOGY

Genomic variation in two gametocyte non-producing Plasmodium falciparum clonal lines

(2016) Susana Campino et al.   MALARIA JOURNAL

Integrated transcriptomic and proteomic analyses ofP. falciparumgametocytes: molecular insight into sex-specific processes and translational repression

(2016) Edwin Lasonder et al.   NUCLEIC ACIDS RESEARCH

EuPathDB: the eukaryotic pathogen genomics database resource

(2016) Cristina Aurrecoechea et al.   NUCLEIC ACIDS RESEARCH

Selective sweep suggests transcriptional regulation may underliePlasmodium vivaxresilience to malaria control measures in Cambodia

(2016) Christian M. Parobek et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mutation tendency of mutator Plasmodium berghei with proofreading-deficient DNA polymerase δ

(2016) Hajime Honma et al.   Scientific Reports

Proteome-wide analysis reveals widespread lysine acetylation of major protein complexes in the malaria parasite

(2016) Simon A. Cobbold et al.   Scientific Reports

A Plasmodium Falciparum Bromodomain Protein Regulates Invasion Gene Expression

(2015) Gabrielle A. Josling et al.   Cell Host & Microbe

Specific expression and export of the Plasmodium falciparum Gametocyte EXported Protein-5 marks the gametocyte ring stage

(2015) Marta Tibúrcio et al.   MALARIA JOURNAL

Global transcriptional repression: An initial and essential step forPlasmodiumsexual development

(2015) Masao Yuda et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Transcriptional profiling defines dynamics of parasite tissue sequestration during malaria infection

(2015) Karell G Pelle et al.   Genome Medicine

ApiAP2 Factors as Candidate Regulators of Stochastic Commitment to Merozoite Production in Theileria annulata

(2015) Marta Pieszko et al.   PLoS Neglected Tropical Diseases

Genome-Wide Identification of the Target Genes of AP2-O, a Plasmodium AP2-Family Transcription Factor

(2015) Izumi Kaneko et al.   PLoS Pathogens

Translational regulation during stage transitions in malaria parasites

(2014) Liwang Cui et al.   Annals of the New York Academy of Sciences

Toxoplasma gondii merozoite gene expression analysis with comparison to the life cycle discloses a unique expression state during enteric development

(2014) Michael S Behnke et al.   BMC GENOMICS

Heterochromatin Protein 1 Secures Survival and Transmission of Malaria Parasites

(2014) Nicolas M.B. Brancucci et al.   Cell Host & Microbe

A Plasmodium falciparum Histone Deacetylase Regulates Antigenic Variation and Gametocyte Conversion

(2014) Bradley I. Coleman et al.   Cell Host & Microbe

Toxoplasmadevelopment - turn the switch on or off?

(2014) Michael W. White et al.   CELLULAR MICROBIOLOGY

Endoplasmic Reticulum Stress Triggers Gametocytogenesis in the Malaria Parasite

(2014) Shweta Chaubey et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A cascade of DNA-binding proteins for sexual commitment and development in Plasmodium

(2014) Abhinav Sinha et al.   NATURE

A transcriptional switch underlies commitment to sexual development in malaria parasites

(2014) Björn F. C. Kafsack et al.   NATURE

TheCryptosporidium parvumApiAP2 gene family: insights into the evolution of apicomplexan AP2 regulatory systems

(2014) Jenna Oberstaller et al.   NUCLEIC ACIDS RESEARCH

A Genome Wide Association Study of Plasmodium falciparum Susceptibility to 22 Antimalarial Drugs in Kenya

(2014) Jason P. Wendler et al.   PLoS One

Distinct Strains of Toxoplasma gondii Feature Divergent Transcriptomes Regardless of Developmental Stage

(2014) Matthew McKnight Croken et al.   PLoS One

Lysine Acetyltransferase GCN5b Interacts with AP2 Factors and Is Required for Toxoplasma gondii Proliferation

(2014) Jiachen Wang et al.   PLoS Pathogens

Genome-wide upstream motif analysis of Cryptosporidium parvum genes clustered by expression profile

(2013) Jenna Oberstaller et al.   BMC GENOMICS

Epigenetic regulation of the Plasmodium falciparum genome

(2013) M. F. Duffy et al.   Briefings in Functional Genomics

Cryptosporidium Pathogenicity and Virulence

(2013) Maha Bouzid et al.   CLINICAL MICROBIOLOGY REVIEWS

Identification of a Novel and Unique Transcription Factor in the Intraerythrocytic Stage of Plasmodium falciparum

(2013) Kanako Komaki-Yasuda et al.   PLoS One

Transposon mutagenesis identifies genes essential for Plasmodium falciparum gametocytogenesis

(2013) H. Ikadai et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

ApiAP2 transcription factor restricts development of the Toxoplasma tissue cyst

(2013) J. B. Radke et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Polysome profiling reveals translational control of gene expression in the human malaria parasite Plasmodium falciparum

(2013) Evelien M Bunnik et al.   GENOME BIOLOGY

A Tetracycline-Repressible Transactivator System to Study Essential Genes in Malaria Parasites

(2012) Paco Pino et al.   Cell Host & Microbe

Transcriptional variation in the malaria parasite Plasmodium falciparum

(2012) N. Rovira-Graells et al.   GENOME RESEARCH

TheToxoplasmanuclear factor TgAP2XI-4 controls bradyzoite gene expression and cyst formation

(2012) Robert Walker et al.   MOLECULAR MICROBIOLOGY

Cactin is essential for G1 progression in Toxoplasma gondii

(2012) Tomasz Szatanek et al.   MOLECULAR MICROBIOLOGY

The Cryptosporidium Parvum Transcriptome during In Vitro Development

(2012) Mary J. Mauzy et al.   PLoS One

Transcriptomic Analysis of Toxoplasma Development Reveals Many Novel Functions and Structures Specific to Sporozoites and Oocysts

(2012) Heather M. Fritz et al.   PLoS One

Identification of an AP2-family Protein That Is Critical for Malaria Liver Stage Development

(2012) Shiroh Iwanaga et al.   PLoS One

Molecular target validation, antimicrobial delivery, and potential treatment of Toxoplasma gondii infections

(2012) B.-S. Lai et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

DNA-binding domains of plant-specific transcription factors: structure, function, and evolution

(2012) Kazuhiko Yamasaki et al.   TRENDS IN PLANT SCIENCE

A View on the Role of Epigenetics in the Biology of Malaria Parasites

(2012) Alfred Cortés et al.   PLoS Pathogens

Plasmodium falciparum Gametocyte Development 1 (Pfgdv1) and Gametocytogenesis Early Gene Identification and Commitment to Sexual Development

(2012) Saliha Eksi et al.   PLoS Pathogens

Organellar proteomics reveals hundreds of novel nuclear proteins in the malaria parasite Plasmodium falciparum

(2012) Sophie C Oehring et al.   GENOME BIOLOGY

Directional gene expression and antisense transcripts in sexual and asexual stages of Plasmodium falciparum

(2011) María J López-Barragán et al.   BMC GENOMICS

Identification of Tissue Cyst Wall Components by Transcriptome Analysis of In Vivo and In Vitro Toxoplasma gondii Bradyzoites

(2011) Kerry R. Buchholz et al.   EUKARYOTIC CELL

In silico and biological survey of transcription-associated proteins implicated in the transcriptional machinery during the erythrocytic development of Plasmodium falciparum

(2010) Emmanuel Bischoff et al.   BMC GENOMICS

Conservation and divergence of known apicomplexan transcriptional regulons

(2010) Kobby Essien et al.   BMC GENOMICS

New insights into the blood-stage transcriptome ofPlasmodium falciparumusing RNA-Seq

(2010) Thomas D. Otto et al.   MOLECULAR MICROBIOLOGY

SAP1 is a critical post-transcriptional regulator of infectivity in malaria parasite sporozoite stages

(2010) Ahmed S. I. Aly et al.   MOLECULAR MICROBIOLOGY

Cell cycle-dependent, intercellular transmission of Toxoplasma gondii is accompanied by marked changes in parasite gene expression

(2010) Rajshekhar Y. Gaji et al.   MOLECULAR MICROBIOLOGY

Coordinated Progression through Two Subtranscriptomes Underlies the Tachyzoite Cycle of Toxoplasma gondii

(2010) Michael S. Behnke et al.   PLoS One

A Genetic Screen for Attenuated Growth Identifies Genes Crucial for Intraerythrocytic Development of Plasmodium falciparum

(2010) Bharath Balu et al.   PLoS One

Identification and Characterization of a Liver Stage-Specific Promoter Region of the Malaria Parasite Plasmodium

(2010) Susanne Helm et al.   PLoS One

Whole-genome sequencing and microarray analysis of ex vivo Plasmodium vivax reveal selective pressure on putative drug resistance genes

(2010) N. V. Dharia et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A common red algal origin of the apicomplexan, dinoflagellate, and heterokont plastids

(2010) J. Janouskovec et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Identification and Genome-Wide Prediction of DNA Binding Specificities for the ApiAP2 Family of Regulators from the Malaria Parasite

(2010) Tracey L. Campbell et al.   PLoS Pathogens

A Major Role for the Plasmodium falciparum ApiAP2 Protein PfSIP2 in Chromosome End Biology

(2010) Christian Flueck et al.   PLoS Pathogens

Universal Features of Post-Transcriptional Gene Regulation Are Critical for Plasmodium Zygote Development

(2010) Gunnar R. Mair et al.   PLoS Pathogens

H2A.Z Demarcates Intergenic Regions of the Plasmodium falciparum Epigenome That Are Dynamically Marked by H3K9ac and H3K4me3

(2010) Richárd Bártfai et al.   PLoS Pathogens

Identification of putative regulatory motifs in the upstream regions of co-expressed functional groups of genes in Plasmodium falciparum

(2009) Prathima Iengar et al.   BMC GENOMICS

Structural Determinants of DNA Binding by a P. falciparum ApiAP2 Transcriptional Regulator

(2009) Scott E. Lindner et al.   JOURNAL OF MOLECULAR BIOLOGY

Identification of a transcription factor in the mosquito-invasive stage of malaria parasites

(2009) Masao Yuda et al.   MOLECULAR MICROBIOLOGY

Transcription factor AP2-Sp and its target genes in malarial sporozoites

(2009) Masao Yuda et al.   MOLECULAR MICROBIOLOGY

In silico discovery of transcription regulatory elements in Plasmodium falciparum

(2008) Jason A Young et al.   BMC GENOMICS

Exported Proteins Required for Virulence and Rigidity of Plasmodium falciparum-Infected Human Erythrocytes

(2008) Alexander G. Maier et al.   CELL

The cell cycle and Toxoplasma gondii cell division: Tightly knit or loosely stitched?

(2008) Marc-Jan Gubbels et al.   INTERNATIONAL JOURNAL FOR PARASITOLOGY

High Mobility Group Protein HMGB2 Is a Critical Regulator ofPlasmodiumOocyst Development

(2008) Mathieu Gissot et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Targeted deletion ofSAP1abolishes the expression of infectivity factors necessary for successful malaria parasite liver infection

(2008) Ahmed S. I. Aly et al.   MOLECULAR MICROBIOLOGY

The transcription of bradyzoite genes inToxoplasma gondiiis controlled by autonomous promoter elements

(2008) Michael S. Behnke et al.   MOLECULAR MICROBIOLOGY

Specific DNA-binding by Apicomplexan AP2 transcription factors

(2008) E. K. De Silva et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A Sporozoite Asparagine-Rich Protein Controls Initiation of Plasmodium Liver Stage Development

(2008) Olivier Silvie et al.   PLoS Pathogens

Comparative genomics of transcription factors and chromatin proteins in parasitic protists and other eukaryotes

(2007) Lakshminarayan M. Iyer et al.   INTERNATIONAL JOURNAL FOR PARASITOLOGY