Epigenetic regulation of the Plasmodium falciparum genome

Horizontal gene transfer of epigenetic machinery and evolution of parasitism in the malaria parasite Plasmodium falciparum and other apicomplexans

(2013) Sandeep P Kishore et al.   BMC EVOLUTIONARY BIOLOGY

Nuclear Pores and Perinuclear Expression Sites of var and Ribosomal DNA Genes Correspond to Physically Distinct Regions in Plasmodium falciparum

(2013) Julien Guizetti et al.   EUKARYOTIC CELL

PfSec13 is an unusual chromatin-associated nucleoporin of Plasmodium falciparum that is essential for parasite proliferation in human erythrocytes

(2013) N. Dahan-Pasternak et al.   JOURNAL OF CELL SCIENCE

Histone Variant H2A.Z Functions in Sister Chromatid Cohesion in Saccharomyces cerevisiae

(2013) Upasna Sharma et al.   MOLECULAR AND CELLULAR BIOLOGY

H2A.Z and H2B.Z double-variant nucleosomes define intergenic regions and dynamically occupyvargene promoters in the malaria parasitePlasmodium falciparum

(2013) Michaela Petter et al.   MOLECULAR MICROBIOLOGY

Extensive lysine acetylation occurs in evolutionarily conserved metabolic pathways and parasite-specific functions duringPlasmodium falciparumintraerythrocytic development

(2013) Jun Miao et al.   MOLECULAR MICROBIOLOGY

H2A.Z/H2B.Z double-variant nucleosomes inhabit the AT-rich promoter regions of thePlasmodium falciparumgenome

(2013) Wieteke A. M. Hoeijmakers et al.   MOLECULAR MICROBIOLOGY

PfSETvs methylation of histone H3K36 represses virulence genes in Plasmodium falciparum

(2013) Lubin Jiang et al.   NATURE

Comprehensive Histone Phosphorylation Analysis and Identification of Pf14-3-3 Protein as a Histone H3 Phosphorylation Reader in Malaria Parasites

(2013) Eeshita G. Dastidar et al.   PLoS One

Sir2a regulates rDNA transcription and multiplication rate in the human malaria parasite Plasmodium falciparum

(2013) Liliana Mancio-Silva et al.   Nature Communications

Dynamic Epigenetic Regulation of Gene Expression during the Life Cycle of Malaria Parasite Plasmodium falciparum

(2013) Archna P. Gupta et al.   PLoS Pathogens

Antimalarial Activity of the Anticancer Histone Deacetylase Inhibitor SB939

(2012) Subathdrage D. M. Sumanadasa et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Chromatin domains, insulators, and the regulation of gene expression

(2012) Rodolfo Ghirlando et al.   Biochimica et Biophysica Acta-Gene Regulatory Mechanisms

PfSET10, a Plasmodium falciparum Methyltransferase, Maintains the Active var Gene in a Poised State during Parasite Division

(2012) Jennifer C. Volz et al.   Cell Host & Microbe

Plasmodium falciparumcentromeres display a unique epigenetic makeup and cluster prior to and during schizogony

(2012) Wieteke A. M. Hoeijmakers et al.   CELLULAR MICROBIOLOGY

The role of chromatin in Plasmodium gene expression

(2012) Michael F. Duffy et al.   CELLULAR MICROBIOLOGY

Centromeric heterochromatin assembly in fission yeast—balancing transcription, RNA interference and chromatin modification

(2012) Benjamin J. Alper et al.   CHROMOSOME RESEARCH

Transcriptional variation in the malaria parasite Plasmodium falciparum

(2012) N. Rovira-Graells et al.   GENOME RESEARCH

Epigenetic Dysregulation of Virulence Gene Expression in Severe Plasmodium falciparum Malaria

(2012) Catherine J. Merrick et al.   JOURNAL OF INFECTIOUS DISEASES

Two long non-coding RNAs generated from subtelomeric regions accumulate in a novel perinuclear compartment in Plasmodium falciparum

(2012) Miguel Sierra-Miranda et al.   MOLECULAR AND BIOCHEMICAL PARASITOLOGY

An inverse relationship to germline transcription defines centromeric chromatin in C. elegans

(2012) Reto Gassmann et al.   NATURE

The role of N-terminus of Plasmodium falciparum ORC1 in telomeric localization and var gene silencing

(2012) Abhijit S. Deshmukh et al.   NUCLEIC ACIDS RESEARCH

Centromere Plasmid: A New Genetic Tool for the Study of Plasmodium falciparum

(2012) Shiroh Iwanaga et al.   PLoS One

Curcumin-Arteether Combination Therapy of Plasmodium berghei-Infected Mice Prevents Recrudescence Through Immunomodulation

(2012) Palakkod G. Vathsala et al.   PLoS One

Comparative Gene Expression Profiling of P. falciparum Malaria Parasites Exposed to Three Different Histone Deacetylase Inhibitors

(2012) Katherine T. Andrews et al.   PLoS One

Insulator-like pairing elements regulate silencing and mutually exclusive expression in the malaria parasite Plasmodium falciparum

(2012) I. Avraham et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Small-molecule histone methyltransferase inhibitors display rapid antimalarial activity against all blood stage forms in Plasmodium falciparum

(2012) N. A. Malmquist et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Placing the Plasmodium falciparum epigenome on the map

(2012) Wieteke A.M. Hoeijmakers et al.   TRENDS IN PARASITOLOGY

A unified phylogeny-based nomenclature for histone variants

(2012) Paul B Talbert et al.   Epigenetics & Chromatin

Organellar proteomics reveals hundreds of novel nuclear proteins in the malaria parasite Plasmodium falciparum

(2012) Sophie C Oehring et al.   GENOME BIOLOGY

Directional gene expression and antisense transcripts in sexual and asexual stages of Plasmodium falciparum

(2011) María J López-Barragán et al.   BMC GENOMICS

Malaria Parasite clag3 Genes Determine Channel-Mediated Nutrient Uptake by Infected Red Blood Cells

(2011) Wang Nguitragool et al.   CELL

A Critical Role of Perinuclear Filamentous Actin in Spatial Repositioning and Mutually Exclusive Expression of Virulence Genes in Malaria Parasites

(2011) Qingfeng Zhang et al.   Cell Host & Microbe

The Phosphoproteomes of Plasmodium falciparum and Toxoplasma gondii Reveal Unusual Adaptations Within and Beyond the Parasites' Boundaries

(2011) Moritz Treeck et al.   Cell Host & Microbe

The double face of the histone variant H3.3

(2011) Emmanuelle Szenker et al.   CELL RESEARCH

Experimentally controlled downregulation of the histone chaperone FACT in Plasmodium berghei reveals that it is critical to male gamete fertility

(2011) Eliane C. Laurentino et al.   CELLULAR MICROBIOLOGY

3D nuclear architecture reveals coupled cell cycle dynamics of chromatin and nuclear pores in the malaria parasite Plasmodium falciparum

(2011) Allon Weiner et al.   CELLULAR MICROBIOLOGY

Acetylation of H2A.Z is a key epigenetic modification associated with gene deregulation and epigenetic remodeling in cancer

(2011) F. Valdes-Mora et al.   GENOME RESEARCH

Signaling epigenetics: Novel insights on cell signaling and epigenetic regulation

(2011) Rodrigo G. Arzate-Mejía et al.   IUBMB LIFE

Heterochromatin formation in bistable chromatin domains controls the epigenetic repression of clonally variant Plasmodium falciparum genes linked to erythrocyte invasion

(2011) Valerie M. Crowley et al.   MOLECULAR MICROBIOLOGY

Expression of P. falciparum var Genes Involves Exchange of the Histone Variant H2A.Z at the Promoter

(2011) Michaela Petter et al.   PLoS Pathogens

A global transcriptional analysis of Plasmodium falciparum malaria reveals a novel family of telomere-associated lncRNAs

(2011) Kate M Broadbent et al.   GENOME BIOLOGY

Activity of the Histone Deacetylase Inhibitor FR235222 on Toxoplasma gondii: Inhibition of Stage Conversion of the Parasite Cyst Form and Study of New Derivative Compounds

(2010) D. Maubon et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Ex VivoActivity of Histone Deacetylase Inhibitors against Multidrug-Resistant Clinical Isolates ofPlasmodium falciparumandP. vivax

(2010) Jutta Marfurt et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

In silico and biological survey of transcription-associated proteins implicated in the transcriptional machinery during the erythrocytic development of Plasmodium falciparum

(2010) Emmanuel Bischoff et al.   BMC GENOMICS

Functional Identification of the Plasmodium Centromere and Generation of a Plasmodium Artificial Chromosome

(2010) Shiroh Iwanaga et al.   Cell Host & Microbe

Chromatin-Mediated Epigenetic Regulation in the Malaria Parasite Plasmodium falciparum

(2010) Liwang Cui et al.   EUKARYOTIC CELL

Nucleosome landscape and control of transcription in the human malaria parasite

(2010) N. Ponts et al.   GENOME RESEARCH

The progression of the intra-erythrocytic cell cycle of Plasmodium falciparum and the role of the centriolar plaques in asynchronous mitotic division during schizogony

(2010) David E. Arnot et al.   INTERNATIONAL JOURNAL FOR PARASITOLOGY

Daxx is an H3.3-specific histone chaperone and cooperates with ATRX in replication-independent chromatin assembly at telomeres

(2010) P. W. Lewis et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Clustering of dispersed ribosomal DNA and its role in gene regulation and chromosome-end associations in malaria parasites

(2010) L. Mancio-Silva et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Transcriptional silencing functions of the yeast protein Orc1/Sir3 subfunctionalized after gene duplication

(2010) M. A. Hickman et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Epigenetic control of the variable expression of a Plasmodium falciparum receptor protein for erythrocyte invasion

(2010) L. Jiang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A common red algal origin of the apicomplexan, dinoflagellate, and heterokont plastids

(2010) J. Janouskovec et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Toxoplasma gondii Lysine Acetyltransferase GCN5-A Functions in the Cellular Response to Alkaline Stress and Expression of Cyst Genes

(2010) Arunasalam Naguleswaran et al.   PLoS Pathogens

A Major Role for the Plasmodium falciparum ApiAP2 Protein PfSIP2 in Chromosome End Biology

(2010) Christian Flueck et al.   PLoS Pathogens

Surface Co-Expression of Two Different PfEMP1 Antigens on Single Plasmodium falciparum-Infected Erythrocytes Facilitates Binding to ICAM1 and PECAM1

(2010) Louise Joergensen et al.   PLoS Pathogens

Histone Deacetylases Play a Major Role in the Transcriptional Regulation of the Plasmodium falciparum Life Cycle

(2010) Balbir K. Chaal et al.   PLoS Pathogens

H2A.Z Demarcates Intergenic Regions of the Plasmodium falciparum Epigenome That Are Dynamically Marked by H3K9ac and H3K4me3

(2010) Richárd Bártfai et al.   PLoS Pathogens

Development and characterization of lysine based tripeptide analogues as inhibitors of Sir2 activity

(2009) Subhra Prakash Chakrabarty et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Genome-wide nucleosome mapping of Plasmodium falciparum reveals histone-rich coding and histone-poor intergenic regions and chromatin remodeling of core and subtelomeric genes

(2009) Scott J Westenberger et al.   BMC GENOMICS

Genome-wide Analysis of Heterochromatin Associates Clonally Variant Gene Regulation with Perinuclear Repressive Centers in Malaria Parasites

(2009) Jose-Juan Lopez-Rubio et al.   Cell Host & Microbe

Four histone variants mark the boundaries of polycistronic transcription units in Trypanosoma brucei

(2009) T. N. Siegel et al.   GENES & DEVELOPMENT

Comparative analysis of H2A.Z nucleosome organization in the human and yeast genomes

(2009) M. Y. Tolstorukov et al.   GENOME RESEARCH

Drug inhibition of HDAC3 and epigenetic control of differentiation in Apicomplexa parasites

(2009) Alexandre Bougdour et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Identification and Characterization of Small Molecule Inhibitors of a Class I Histone Deacetylase fromPlasmodium falciparum

(2009) Vishal Patel et al.   JOURNAL OF MEDICINAL CHEMISTRY

Toxoplasma H2A Variants Reveal Novel Insights into Nucleosome Composition and Functions for this Histone Family

(2009) Maria C. Dalmasso et al.   JOURNAL OF MOLECULAR BIOLOGY

Global Histone Analysis by Mass Spectrometry Reveals a High Content of Acetylated Lysine Residues in the Malaria ParasitePlasmodium falciparum

(2009) Morten B. Trelle et al.   JOURNAL OF PROTEOME RESEARCH

Clonally variant gene families inPlasmodium falciparumshare a common activation factor

(2009) Cali A. Howitt et al.   MOLECULAR MICROBIOLOGY

Identification of a transcription factor in the mosquito-invasive stage of malaria parasites

(2009) Masao Yuda et al.   MOLECULAR MICROBIOLOGY

Transcription factor AP2-Sp and its target genes in malarial sporozoites

(2009) Masao Yuda et al.   MOLECULAR MICROBIOLOGY

Transcriptional profiling of growth perturbations of the human malaria parasite Plasmodium falciparum

(2009) Guangan Hu et al.   NATURE BIOTECHNOLOGY

H3.3/H2A.Z double variant–containing nucleosomes mark 'nucleosome-free regions' of active promoters and other regulatory regions

(2009) Chunyuan Jin et al.   NATURE GENETICS

Dynamic histone H3 epigenome marking during the intraerythrocytic cycle of Plasmodium falciparum

(2009) A. M. Salcedo-Amaya et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Sir2 Paralogues Cooperate to Regulate Virulence Genes and Antigenic Variation in Plasmodium falciparum

(2009) Christopher J Tonkin et al.   PLOS BIOLOGY

Plasmodium falciparum Heterochromatin Protein 1 Marks Genomic Loci Linked to Phenotypic Variation of Exported Virulence Factors

(2009) Christian Flueck et al.   PLoS Pathogens

Simultaneous transcription of duplicated var2csa gene copies in individual Plasmodium falciparum parasites

(2009) Kim JM Brolin et al.   GENOME BIOLOGY

Antigenic Variation in Plasmodium falciparum

(2008) Artur Scherf et al.   Annual Review of Microbiology

Antimalarial Activity of Phenylthiazolyl-Bearing Hydroxamate-Based Histone Deacetylase Inhibitors

(2008) G. S. Dow et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Trypanosome H2Bv replaces H2B in nucleosomes enriched for H3 K4 and K76 trimethylation

(2008) Veena Mandava et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Identification of a novel post-translational modification inPlasmodium falciparum: protein sumoylation in different cellular compartments

(2008) Neha Issar et al.   CELLULAR MICROBIOLOGY

Histone Acetyltransferase Inhibitor Anacardic Acid Causes Changes in Global Gene Expression during In VitroPlasmodium falciparumDevelopment

(2008) Long Cui et al.   EUKARYOTIC CELL

Nicotinamide inhibits Plasmodium falciparum Sir2 activity in vitro and parasite growth

(2008) Dhaneswar Prusty et al.   FEMS MICROBIOLOGY LETTERS

Histone lysine methyltransferases and demethylases in Plasmodium falciparum

(2008) Liwang Cui et al.   INTERNATIONAL JOURNAL FOR PARASITOLOGY

An apicomplexan ankyrin-repeat histone deacetylase with relatives in photosynthetic eukaryotes

(2008) S. Dean Rider et al.   INTERNATIONAL JOURNAL FOR PARASITOLOGY

Differential association of Orc1 and Sir2 proteins to telomeric domains in Plasmodium falciparum

(2008) L. Mancio-Silva et al.   JOURNAL OF CELL SCIENCE

Differential sub-nuclear localisation of repressive and activating histone methyl modifications in P. falciparum

(2008) Neha Issar et al.   MICROBES AND INFECTION

Chromatin associated sense and antisense noncoding RNAs are transcribed from the var gene family of virulence genes of the malaria parasite Plasmodium falciparum

(2008) C. Epp et al.   RNA

Comparative genomics of transcription factors and chromatin proteins in parasitic protists and other eukaryotes

(2007) Lakshminarayan M. Iyer et al.   INTERNATIONAL JOURNAL FOR PARASITOLOGY