Piezo2 channel regulates RhoA and actin cytoskeleton to promote cell mechanobiological responses

Mechanotransduction pulls the strings of matrix degradation at invadosome

(2017) Sanela Mrkonjic et al.   MATRIX BIOLOGY

Focal adhesions, stress fibers and mechanical tension

(2016) Keith Burridge et al.   EXPERIMENTAL CELL RESEARCH

Metastatic colonization by circulating tumour cells

(2016) Joan Massagué et al.   NATURE

Confinement Sensing and Signal Optimization via Piezo1/PKA and Myosin II Pathways

(2016) Wei-Chien Hung et al.   Cell Reports

A critical role for Piezo2 channels in the mechanotransduction of mouse proprioceptive neurons

(2016) Danny Florez-Paz et al.   Scientific Reports

The focal adhesion kinase Pyk2 links Ca2+signalling to Src family kinase activation and protein tyrosine phosphorylation in thrombin-stimulated platelets

(2015) Ilaria Canobbio et al.   BIOCHEMICAL JOURNAL

Actin remodeling confers BRAF inhibitor resistance to melanoma cells through YAP/TAZ activation

(2015) M. H. Kim et al.   EMBO JOURNAL

Piezo2 is the principal mechanotransduction channel for proprioception

(2015) Seung-Hyun Woo et al.   NATURE NEUROSCIENCE

TRPV4 participates in the establishment of trailing adhesions and directional persistence of migrating cells

(2015) Sanela Mrkonjić et al.   PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY

Tissue-based map of the human proteome

(2015) M. Uhlen et al.   SCIENCE

Piezo1 forms mechanosensitive ion channels in the human MCF-7 breast cancer cell line

(2015) Chouyang Li et al.   Scientific Reports

Mutations in PIEZO2 Cause Gordon Syndrome, Marden-Walker Syndrome, and Distal Arthrogryposis Type 5

(2014) Margaret J. McMillin et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Serpins Promote Cancer Cell Survival and Vascular Co-Option in Brain Metastasis

(2014) Manuel Valiente et al.   CELL

Water Permeation Drives Tumor Cell Migration in Confined Microenvironments

(2014) Kimberly M. Stroka et al.   CELL

Piezo2 is required for Merkel-cell mechanotransduction

(2014) Seung-Hyun Woo et al.   NATURE

Stretch-activated ion channel Piezo1 directs lineage choice in human neural stem cells

(2014) Medha M. Pathak et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Invadopodia Are Required for Cancer Cell Extravasation and Are a Therapeutic Target for Metastasis

(2014) Hon S. Leong et al.   Cell Reports

Gain-of-function mutations in the mechanically activated ion channel PIEZO2 cause a subtype of Distal Arthrogryposis

(2013) B. Coste et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mechanically activated fyn utilizes mTORC2 to regulate RhoA and adipogenesis in mesenchymal stem cells

(2013) William R. Thompson et al.   STEM CELLS

Tension is required but not sufficient for focal adhesion maturation without a stress fiber template

(2012) Patrick W. Oakes et al.   JOURNAL OF CELL BIOLOGY

Crowding induces live cell extrusion to maintain homeostatic cell numbers in epithelia

(2012) George T. Eisenhoffer et al.   NATURE

Role of Ion Channels and Transporters in Cell Migration

(2012) Albrecht Schwab et al.   PHYSIOLOGICAL REVIEWS

Cancer Invasion and the Microenvironment: Plasticity and Reciprocity

(2011) Peter Friedl et al.   CELL

The Hippo Transducer TAZ Confers Cancer Stem Cell-Related Traits on Breast Cancer Cells

(2011) Michelangelo Cordenonsi et al.   CELL

Rho Signaling Regulates Pannexin 1-mediated ATP Release from Airway Epithelia

(2011) Lucia Seminario-Vidal et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Hydrodynamic Cellular Volume Changes Enable Glioma Cell Invasion

(2011) S. Watkins et al.   JOURNAL OF NEUROSCIENCE

Role of YAP/TAZ in mechanotransduction

(2011) Sirio Dupont et al.   NATURE

The Rho GEFs LARG and GEF-H1 regulate the mechanical response to force on integrins

(2011) Christophe Guilluy et al.   NATURE CELL BIOLOGY

The TRPV4 Channel Contributes to Intercellular Junction Formation in Keratinocytes

(2010) Takaaki Sokabe et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Piezo1 and Piezo2 Are Essential Components of Distinct Mechanically Activated Cation Channels

(2010) B. Coste et al.   SCIENCE

An online survival analysis tool to rapidly assess the effect of 22,277 genes on breast cancer prognosis using microarray data of 1,809 patients

(2009) Balazs Györffy et al.   BREAST CANCER RESEARCH AND TREATMENT

Integrin activation by Fam38A uses a novel mechanism of R-Ras targeting to the endoplasmic reticulum

(2009) B. J. McHugh et al.   JOURNAL OF CELL SCIENCE

Force-induced cell polarisation is linked to RhoA-driven microtubule-independent focal-adhesion sliding

(2009) A. M. Goldyn et al.   JOURNAL OF CELL SCIENCE

Actin machinery and mechanosensitivity in invadopodia, podosomes and focal adhesions

(2009) C. Albiges-Rizo et al.   JOURNAL OF CELL SCIENCE

Visualization of small GTPase activity with fluorescence resonance energy transfer-based biosensors

(2009) Kazuhiro Aoki et al.   Nature Protocols

Non-muscle myosin II takes centre stage in cell adhesion and migration

(2009) Miguel Vicente-Manzanares et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

The calpain small subunit regulates cell-substrate mechanical interactions during fibroblast migration

(2008) V. V. Undyala et al.   JOURNAL OF CELL SCIENCE