Integrative multi-omic analysis identifies new drivers and pathways in molecularly distinct subtypes of ALS
Published 2019 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Integrative multi-omic analysis identifies new drivers and pathways in molecularly distinct subtypes of ALS
Authors
Keywords
-
Journal
Scientific Reports
Volume 9, Issue 1, Pages -
Publisher
Springer Science and Business Media LLC
Online
2019-07-10
DOI
10.1038/s41598-019-46355-w
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Assessment of somatic single-nucleotide variation in brain tissue of cases with schizophrenia
- (2019) John F. Fullard et al. Translational Psychiatry
- Hot-spot KIF5A mutations cause familial ALS
- (2018) David Brenner et al. BRAIN
- Current knowledge and recent insights into the genetic basis of amyotrophic lateral sclerosis
- (2018) Alexander E. Volk et al. Medizinische Genetik
- Genome-wide Analyses Identify KIF5A as a Novel ALS Gene
- (2018) Aude Nicolas et al. NEURON
- Somatic mutations in the human brain: implications for psychiatric research
- (2018) Masaki Nishioka et al. MOLECULAR PSYCHIATRY
- New molecular diagnostic trends and biomarkers for amyotrophic lateral sclerosis
- (2018) Georgios Pampalakis et al. HUMAN MUTATION
- Copy Number Variations in Amyotrophic Lateral Sclerosis: Piecing the Mosaic Tiles Together through a Systems Biology Approach
- (2017) Giovanna Morello et al. MOLECULAR NEUROBIOLOGY
- mTORC1-independent TFEB activation via Akt inhibition promotes cellular clearance in neurodegenerative storage diseases
- (2017) Michela Palmieri et al. Nature Communications
- Comparison of Sirtuin 3 Levels in ALS and Huntington’s Disease—Differential Effects in Human Tissue Samples vs. Transgenic Mouse Models
- (2017) Eva Buck et al. Frontiers in Molecular Neuroscience
- GRP78 at the Centre of the Stage in Cancer and Neuroprotection
- (2017) Caty Casas Frontiers in Neuroscience
- Shortcomings in the Current Amyotrophic Lateral Sclerosis Trials and Potential Solutions for Improvement
- (2017) Nakul Katyal et al. Frontiers in Neurology
- Molecular Taxonomy of Sporadic Amyotrophic Lateral Sclerosis Using Disease-Associated Genes
- (2017) Giovanna Morello et al. Frontiers in Neurology
- Interplay of endoplasmic reticulum stress and autophagy in neurodegenerative disorders
- (2016) Yu Cai et al. Autophagy
- Mislocated FUS is sufficient for gain-of-toxic-function amyotrophic lateral sclerosis phenotypes in mice
- (2016) Gen Shiihashi et al. BRAIN
- Emerging molecular biomarker targets for amyotrophic lateral sclerosis
- (2016) Júlia Costa et al. CLINICA CHIMICA ACTA
- Complement activation at the motor end-plates in amyotrophic lateral sclerosis
- (2016) Nawal Bahia El Idrissi et al. Journal of Neuroinflammation
- Gene discovery in amyotrophic lateral sclerosis: implications for clinical management
- (2016) Ammar Al-Chalabi et al. Nature Reviews Neurology
- A customized high-resolution array-comparative genomic hybridization to explore copy number variations in Parkinson’s disease
- (2016) Valentina La Cognata et al. NEUROGENETICS
- Enrichr: a comprehensive gene set enrichment analysis web server 2016 update
- (2016) Maxim V. Kuleshov et al. NUCLEIC ACIDS RESEARCH
- CSF1R blockade slows the progression of amyotrophic lateral sclerosis by reducing microgliosis and invasion of macrophages into peripheral nerves
- (2016) Anna Martínez-Muriana et al. Scientific Reports
- Transcriptional analysis reveals distinct subtypes in amyotrophic lateral sclerosis: implications for personalized therapy
- (2015) Giovanna Morello et al. Future Medicinal Chemistry
- GRP78/BiP/HSPA5/Dna K is a universal therapeutic target for human disease
- (2015) Laurence Booth et al. JOURNAL OF CELLULAR PHYSIOLOGY
- Molecular classification of amyotrophic lateral sclerosis by unsupervised clustering of gene expression in motor cortex
- (2015) Eleonora Aronica et al. NEUROBIOLOGY OF DISEASE
- Dysregulated expression of death, stress and mitochondrion related genes in the sciatic nerve of presymptomatic SOD1G93A mouse model of Amyotrophic Lateral Sclerosis
- (2015) Chrystian J. Alves et al. Frontiers in Cellular Neuroscience
- A striatal-enriched intronic GPCR modulates huntingtin levels and toxicity
- (2015) Yuwei Yao et al. eLife
- Unique Function of Kinesin Kif5A in Localization of Mitochondria in Axons
- (2014) P. D. Campbell et al. JOURNAL OF NEUROSCIENCE
- STRING v10: protein–protein interaction networks, integrated over the tree of life
- (2014) Damian Szklarczyk et al. NUCLEIC ACIDS RESEARCH
- Blood-CNS Barrier Impairment in ALS patients versus an animal model
- (2014) Svitlana Garbuzova-Davis et al. Frontiers in Cellular Neuroscience
- Jet energy resolution in proton-proton collisions at $\sqrt{\mathrm{s}}=7\mbox{ TeV}$ recorded in 2010 with the ATLAS detector
- (2013) G. Aad et al. EUROPEAN PHYSICAL JOURNAL C
- Immune-mediated Mechanisms in the Pathoprogression of Amyotrophic Lateral Sclerosis
- (2013) Weihua Zhao et al. Journal of Neuroimmune Pharmacology
- Elevated TRAF2/6 expression in Parkinson’s disease is caused by the loss of Parkin E3 ligase activity
- (2013) Ji-Yun Chung et al. LABORATORY INVESTIGATION
- Increased expression of BIN1 mediates Alzheimer genetic risk by modulating tau pathology
- (2013) J Chapuis et al. MOLECULAR PSYCHIATRY
- State of play in amyotrophic lateral sclerosis genetics
- (2013) Alan E Renton et al. NATURE NEUROSCIENCE
- Neuroprotection through Excitability and mTOR Required in ALS Motoneurons to Delay Disease and Extend Survival
- (2013) Smita Saxena et al. NEURON
- MST1 functions as a key modulator of neurodegeneration in a mouse model of ALS
- (2013) J. K. Lee et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Early gene expression changes in spinal cord from SOD1G93A Amyotrophic Lateral Sclerosis animal model
- (2013) Gabriela P. de Oliveira et al. Frontiers in Cellular Neuroscience
- Amyotrophic lateral sclerosis and Huntington’s disease: Neurodegenerative link or coincidence?
- (2013) Suresh Kumar Chhetri et al. Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration
- Pharmacological inhibition of Akt and downstream pathways modulates the expression of COX-2 and mPGES-1 in activated microglia
- (2012) Antonio CP de Oliveira et al. Journal of Neuroinflammation
- A system mathematical model of a cell–cell communication network in amyotrophic lateral sclerosis
- (2012) Hongwei Shao et al. Molecular BioSystems
- Sterol regulatory element binding protein-1 (SREBP1) activation in motor neurons in excitotoxicity and amyotrophic lateral sclerosis (ALS): Indip, a potential therapeutic peptide
- (2011) Changiz Taghibiglou et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- An evidence-based approach to establish the functional and clinical significance of copy number variants in intellectual and developmental disabilities
- (2011) Erin B. Kaminsky et al. GENETICS IN MEDICINE
- Alzheimer risk associated with a copy number variation in the complement receptor 1 increasing C3b/C4b binding sites
- (2011) N Brouwers et al. MOLECULAR PSYCHIATRY
- Role of ubiquitin–proteasome-mediated proteolysis in nervous system disease
- (2010) Ashok N. Hegde et al. Biochimica et Biophysica Acta-Gene Regulatory Mechanisms
- Accurate and objective copy number profiling using real-time quantitative PCR
- (2010) Barbara D’haene et al. METHODS
- Genetic variation of the mitochondrial complex I subunit NDUFV2 and Parkinson’s disease
- (2010) Kenya Nishioka et al. PARKINSONISM & RELATED DISORDERS
- Role of the Unfolded Protein Response Regulator GRP78/BiP in Development, Cancer, and Neurological Disorders
- (2009) Miao Wang et al. ANTIOXIDANTS & REDOX SIGNALING
- Redox Modifier Genes and Pathways in Amyotrophic Lateral Sclerosis
- (2009) Barrie J. Carter et al. ANTIOXIDANTS & REDOX SIGNALING
- Switching Akt: from survival signaling to deadly response
- (2009) Marek Los et al. BIOESSAYS
- Transcriptional response of the neuromuscular system to exercise training and potential implications for ALS
- (2009) Laura Ferraiuolo et al. JOURNAL OF NEUROCHEMISTRY
- The Lysosomal Sialic Acid Transporter Sialin Is Required for Normal CNS Myelination
- (2009) L. M. Prolo et al. JOURNAL OF NEUROSCIENCE
- ER Stress and Unfolded Protein Response in Amyotrophic Lateral Sclerosis
- (2009) Kohsuke Kanekura et al. MOLECULAR NEUROBIOLOGY
- Amyotrophic lateral sclerosis
- (2009) Lokesh C Wijesekera et al. Orphanet Journal of Rare Diseases
- The Role of Copy Number Variation in Susceptibility to Amyotrophic Lateral Sclerosis: Genome-Wide Association Study and Comparison with Published Loci
- (2009) Louise V. Wain et al. PLoS One
- SREBP Activity Is Regulated by mTORC1 and Contributes to Akt-Dependent Cell Growth
- (2008) Thomas Porstmann et al. Cell Metabolism
- Non-P450 aldehyde oxidizing enzymes: the aldehyde dehydrogenase superfamily
- (2008) Satori A Marchitti et al. Expert Opinion on Drug Metabolism & Toxicology
- Copy-number variation in sporadic amyotrophic lateral sclerosis: a genome-wide screen
- (2008) Hylke M Blauw et al. LANCET NEUROLOGY
Discover Peeref hubs
Discuss science. Find collaborators. Network.
Join a conversationPublish scientific posters with Peeref
Peeref publishes scientific posters from all research disciplines. Our Diamond Open Access policy means free access to content and no publication fees for authors.
Learn More