Rare, functional, somatic variants in gene families linked to cancer genes: GPCR signaling as a paradigm
Published 2019 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Rare, functional, somatic variants in gene families linked to cancer genes: GPCR signaling as a paradigm
Authors
Keywords
-
Journal
ONCOGENE
Volume -, Issue -, Pages -
Publisher
Springer Science and Business Media LLC
Online
2019-07-23
DOI
10.1038/s41388-019-0895-2
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Comprehensive Characterization of Cancer Driver Genes and Mutations
- (2018) Matthew H. Bailey et al. CELL
- Cancer genetics meets biomolecular mechanism-bridging an age-old gulf
- (2018) Juan Carlos González-Sánchez et al. FEBS LETTERS
- Mutant GNAS drives pancreatic tumourigenesis by inducing PKA-mediated SIK suppression and reprogramming lipid metabolism
- (2018) Krushna C. Patra et al. NATURE CELL BIOLOGY
- Propranolol for Off-label Treatment of Patients With Melanoma
- (2018) Vincenzo De Giorgi et al. JAMA Oncology
- GNASR201C Induces Pancreatic Cystic Neoplasms in Mice That Express Activated KRAS by Inhibiting YAP1 Signaling
- (2018) Noboru Ideno et al. GASTROENTEROLOGY
- Functional expression of olfactory receptors in human primary melanoma and melanoma metastasis
- (2017) Lian Gelis et al. EXPERIMENTAL DERMATOLOGY
- Comparison of algorithms for the detection of cancer drivers at subgene resolution
- (2017) Eduard Porta-Pardo et al. NATURE METHODS
- Stress hormones promote EGFR inhibitor resistance in NSCLC: Implications for combinations with β-blockers
- (2017) Monique B. Nilsson et al. Science Translational Medicine
- Serotonin Analogues as Inhibitors of Breast Cancer Cell Growth
- (2017) Jiney Jose et al. ACS Medicinal Chemistry Letters
- Dopamine receptor D2 is correlated with gastric cancer prognosis
- (2017) Jiasheng Mu et al. Oncology Letters
- Genetic variants affecting equivalent protein family positions reflect human diversity
- (2017) Francesco Raimondi et al. Scientific Reports
- Functional Characterization of the Odorant Receptor 51E2 in Human Melanocytes
- (2016) Lian Gelis et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- JAK-STAT and G-protein-coupled receptor signaling pathways are frequently altered in epitheliotropic intestinal T-cell lymphoma
- (2016) M-L Nairismägi et al. LEUKEMIA
- Recurrent activating mutations of G-protein-coupled receptor CYSLTR2 in uveal melanoma
- (2016) Amanda R Moore et al. NATURE GENETICS
- Tissue-specific regulatory circuits reveal variable modular perturbations across complex diseases
- (2016) Daniel Marbach et al. NATURE METHODS
- UniProt: the universal protein knowledgebase
- (2016) NUCLEIC ACIDS RESEARCH
- COSMIC: somatic cancer genetics at high-resolution
- (2016) Simon A. Forbes et al. NUCLEIC ACIDS RESEARCH
- g:Profiler—a web server for functional interpretation of gene lists (2016 update)
- (2016) Jüri Reimand et al. NUCLEIC ACIDS RESEARCH
- Inhibition of β2-adrenergic receptor reduces triple-negative breast cancer brain metastases: The potential benefit of perioperative β-blockade
- (2016) CECILIA CHOY et al. ONCOLOGY REPORTS
- Insights into cancer severity from biomolecular interaction mechanisms
- (2016) Francesco Raimondi et al. Scientific Reports
- Universal allosteric mechanism for Gα activation by GPCRs
- (2015) Tilman Flock et al. NATURE
- The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands
- (2015) Christopher Southan et al. NUCLEIC ACIDS RESEARCH
- The Reactome pathway Knowledgebase
- (2015) Antonio Fabregat et al. NUCLEIC ACIDS RESEARCH
- Ensembl 2016
- (2015) Andrew Yates et al. NUCLEIC ACIDS RESEARCH
- The Pfam protein families database: towards a more sustainable future
- (2015) Robert D. Finn et al. NUCLEIC ACIDS RESEARCH
- Inactivating mutations in GNA13 and RHOA in Burkitt’s lymphoma and diffuse large B-cell lymphoma: a tumor suppressor function for the Gα13/RhoA axis in B cells
- (2015) M O'Hayre et al. ONCOGENE
- TRRUST: a reference database of human transcriptional regulatory interactions
- (2015) Heonjong Han et al. Scientific Reports
- GNAS Spectrum of Disorders
- (2015) Serap Turan et al. Current Osteoporosis Reports
- Pan-Cancer Analysis of Mutation Hotspots in Protein Domains
- (2015) Martin L. Miller et al. Cell Systems
- Phase II clinical trial of pasireotide long-acting repeatable in patients with metastatic neuroendocrine tumors
- (2014) M Cives et al. ENDOCRINE-RELATED CANCER
- Detection of long-chain non-encoding RNA differential expression in non-small cell lung cancer by microarray analysis and preliminary verification
- (2014) YUMIN WANG et al. Molecular Medicine Reports
- Loss of signalling via Gα13 in germinal centre B-cell-derived lymphoma
- (2014) Jagan R. Muppidi et al. NATURE
- Pan-cancer network analysis identifies combinations of rare somatic mutations across pathways and protein complexes
- (2014) Mark D M Leiserson et al. NATURE GENETICS
- Mechismo: predicting the mechanistic impact of mutations and modifications on molecular interactions
- (2014) Matthew J. Betts et al. NUCLEIC ACIDS RESEARCH
- AIP inactivation leads to pituitary tumorigenesis through defective Gαi-cAMP signaling
- (2014) I Tuominen et al. ONCOGENE
- Mutation Analysis of Inhibitory Guanine Nucleotide Binding Protein Alpha (GNAI) Loci in Young and Familial Pituitary Adenomas
- (2014) Hande Demir et al. PLoS One
- A melanocyte lineage program confers resistance to MAP kinase pathway inhibition
- (2013) Cory M. Johannessen et al. NATURE
- Mutational heterogeneity in cancer and the search for new cancer-associated genes
- (2013) Michael S. Lawrence et al. NATURE
- Mutational landscape and significance across 12 major cancer types
- (2013) Cyriac Kandoth et al. NATURE
- Cancer Genome Landscapes
- (2013) B. Vogelstein et al. SCIENCE
- Genic Intolerance to Functional Variation and the Interpretation of Personal Genomes
- (2013) Slavé Petrovski et al. PLoS Genetics
- Epigenetic silencing of monoallelically methylated miRNA loci in precancerous colorectal lesions
- (2013) M Menigatti et al. Oncogenesis
- Restructuring G-Protein- Coupled Receptor Activation
- (2012) Martin Audet et al. CELL
- Circuitry and Dynamics of Human Transcription Factor Regulatory Networks
- (2012) Shane Neph et al. CELL
- TGFα shedding assay: an accurate and versatile method for detecting GPCR activation
- (2012) Asuka Inoue et al. NATURE METHODS
- Zinc-finger protein 331, a novel putative tumor suppressor, suppresses growth and invasiveness of gastric cancer
- (2012) J Yu et al. ONCOGENE
- PRDM1 is a tumor suppressor gene in natural killer cell malignancies
- (2011) C. Kucuk et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- β2-adrenergic antagonists suppress pancreatic cancer cell invasion by inhibiting CREB, NF-κB and AP-1
- (2010) Dong Zhang et al. CANCER BIOLOGY & THERAPY
- CF102 an A3 adenosine receptor agonist mediates anti-tumor and anti-inflammatory effects in the liver
- (2010) S. Cohen et al. JOURNAL OF CELLULAR PHYSIOLOGY
- Functional Characterization of Vasopressin Type 2 Receptor Substitutions (R137H/C/L) Leading to Nephrogenic Diabetes Insipidus and Nephrogenic Syndrome of Inappropriate Antidiuresis: Implications for Treatments
- (2010) M. D. Rochdi et al. MOLECULAR PHARMACOLOGY
- Enrichment Map: A Network-Based Method for Gene-Set Enrichment Visualization and Interpretation
- (2010) Daniele Merico et al. PLoS One
- Activation of an Olfactory Receptor Inhibits Proliferation of Prostate Cancer Cells
- (2009) Eva M. Neuhaus et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- The structure and function of G-protein-coupled receptors
- (2009) Daniel M. Rosenbaum et al. NATURE
- Targeting the phosphoinositide 3-kinase pathway in cancer
- (2009) Pixu Liu et al. NATURE REVIEWS DRUG DISCOVERY
- ITFP: an integrated platform of mammalian transcription factors
- (2008) G. Zheng et al. BIOINFORMATICS
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExploreAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started