Tissue-specific regulatory circuits reveal variable modular perturbations across complex diseases
Published 2016 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Tissue-specific regulatory circuits reveal variable modular perturbations across complex diseases
Authors
Keywords
-
Journal
NATURE METHODS
Volume 13, Issue 4, Pages 366-370
Publisher
Springer Nature
Online
2016-03-08
DOI
10.1038/nmeth.3799
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Fast and Rigorous Computation of Gene and Pathway Scores from SNP-Based Summary Statistics
- (2016) David Lamparter et al. PLoS Computational Biology
- Integrative analysis of 111 reference human epigenomes
- (2015) Anshul Kundaje et al. NATURE
- Understanding multicellular function and disease with human tissue-specific networks
- (2015) Casey S Greene et al. NATURE GENETICS
- A predictive modeling approach for cell line-specific long-range regulatory interactions
- (2015) Sushmita Roy et al. NUCLEIC ACIDS RESEARCH
- The Genotype-Tissue Expression (GTEx) pilot analysis: Multitissue gene regulation in humans
- (2015) et al. SCIENCE
- Biological interpretation of genome-wide association studies using predicted gene functions
- (2015) Tune H. Pers et al. Nature Communications
- Sharing and Specificity of Co-expression Networks across 35 Human Tissues
- (2015) Emma Pierson et al. PLoS Computational Biology
- Joint Analysis of Functional Genomic Data and Genome-wide Association Studies of 18 Human Traits
- (2014) Joseph K. Pickrell AMERICAN JOURNAL OF HUMAN GENETICS
- Human Genetics Shape the Gut Microbiome
- (2014) Julia K. Goodrich et al. CELL
- A Proteome-Scale Map of the Human Interactome Network
- (2014) Thomas Rolland et al. CELL
- Identification of Causal Genetic Drivers of Human Disease through Systems-Level Analysis of Regulatory Networks
- (2014) James C. Chen et al. CELL
- A genome-wide association study of anorexia nervosa
- (2014) V Boraska et al. MOLECULAR PSYCHIATRY
- An atlas of active enhancers across human cell types and tissues
- (2014) Robin Andersson et al. NATURE
- A promoter-level mammalian expression atlas
- (2014) NATURE
- Pancreatic islet enhancer clusters enriched in type 2 diabetes risk-associated variants
- (2014) Lorenzo Pasquali et al. NATURE GENETICS
- The multifactorial role of neutrophils in rheumatoid arthritis
- (2014) Helen L. Wright et al. Nature Reviews Rheumatology
- The BioGRID interaction database: 2015 update
- (2014) Andrew Chatr-aryamontri et al. NUCLEIC ACIDS RESEARCH
- Identifying and mapping cell-type-specific chromatin programming of gene expression
- (2014) Troels T. Marstrand et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Coherent Functional Modules Improve Transcription Factor Target Identification, Cooperativity Prediction, and Disease Association
- (2014) Konrad J. Karczewski et al. PLoS Genetics
- A Central Role for GRB10 in Regulation of Islet Function in Man
- (2014) Inga Prokopenko et al. PLoS Genetics
- Integrative Genomics Reveals Novel Molecular Pathways and Gene Networks for Coronary Artery Disease
- (2014) Ville-Petteri Mäkinen et al. PLoS Genetics
- Systematic dissection of regulatory motifs in 2000 predicted human enhancers using a massively parallel reporter assay
- (2013) P. Kheradpour et al. GENOME RESEARCH
- Identification of risk loci with shared effects on five major psychiatric disorders: a genome-wide analysis
- (2013) LANCET
- Discovery and refinement of loci associated with lipid levels
- (2013) Cristen J Willer et al. NATURE GENETICS
- Seven new loci associated with age-related macular degeneration
- (2013) Lars G Fritsche et al. NATURE GENETICS
- Genome-wide association analysis identifies 13 new risk loci for schizophrenia
- (2013) Stephan Ripke et al. NATURE GENETICS
- Meta-analysis of 74,046 individuals identifies 11 new susceptibility loci for Alzheimer's disease
- (2013) Jean-Charles Lambert et al. NATURE GENETICS
- Systematic discovery and characterization of regulatory motifs in ENCODE TF binding experiments
- (2013) P. Kheradpour et al. NUCLEIC ACIDS RESEARCH
- Chromatin stretch enhancer states drive cell-specific gene regulation and harbor human disease risk variants
- (2013) S. C. J. Parker et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Re-Ranking Sequencing Variants in the Post-GWAS Era for Accurate Causal Variant Identification
- (2013) Laura L. Faye et al. PLoS Genetics
- A Validated Regulatory Network for Th17 Cell Specification
- (2012) Maria Ciofani et al. CELL
- Circuitry and Dynamics of Human Transcription Factor Regulatory Networks
- (2012) Shane Neph et al. CELL
- Predictive regulatory models in Drosophila melanogaster by integrative inference of transcriptional networks
- (2012) D. Marbach et al. GENOME RESEARCH
- Annotation of functional variation in personal genomes using RegulomeDB
- (2012) A. P. Boyle et al. GENOME RESEARCH
- Architecture of the human regulatory network derived from ENCODE data
- (2012) Mark B. Gerstein et al. NATURE
- Interpreting noncoding genetic variation in complex traits and human disease
- (2012) Lucas D Ward et al. NATURE BIOTECHNOLOGY
- Developing predictive molecular maps of human disease through community-based modeling
- (2012) Jonathan M J Derry et al. NATURE GENETICS
- Genome-wide meta-analysis identifies 56 bone mineral density loci and reveals 14 loci associated with risk of fracture
- (2012) Karol Estrada et al. NATURE GENETICS
- Chromatin marks identify critical cell types for fine mapping complex trait variants
- (2012) Gosia Trynka et al. NATURE GENETICS
- Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes
- (2012) NATURE GENETICS
- Large-scale association analyses identify new loci influencing glycemic traits and provide insight into the underlying biological pathways
- (2012) Robert A Scott et al. NATURE GENETICS
- Wisdom of crowds for robust gene network inference
- (2012) Daniel Marbach et al. NATURE METHODS
- The 1000 Genomes Project: data management and community access
- (2012) Laura Clarke et al. NATURE METHODS
- Genome-Wide Association Identifies Nine Common Variants Associated With Fasting Proinsulin Levels and Provides New Insights Into the Pathophysiology of Type 2 Diabetes
- (2011) R. J. Strawbridge et al. DIABETES
- Prioritizing candidate disease genes by network-based boosting of genome-wide association data
- (2011) I. Lee et al. GENOME RESEARCH
- Genetic variants in novel pathways influence blood pressure and cardiovascular disease risk
- (2011) Georg B. Ehret et al. NATURE
- Genetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis
- (2011) Stephen Sawcer et al. NATURE
- Large-scale association analysis identifies 13 new susceptibility loci for coronary artery disease
- (2011) Heribert Schunkert et al. NATURE GENETICS
- Meta-analysis identifies 29 additional ulcerative colitis risk loci, increasing the number of confirmed associations to 47
- (2011) Carl A Anderson et al. NATURE GENETICS
- Role of the endothelium in inflammatory bowel diseases
- (2011) Walter E Cromer WORLD JOURNAL OF GASTROENTEROLOGY
- Proteins Encoded in Genomic Regions Associated with Immune-Mediated Disease Physically Interact and Suggest Underlying Biology
- (2011) Elizabeth J. Rossin et al. PLoS Genetics
- DA DA: Degree-Aware Algorithms for Network-Based Disease Gene Prioritization
- (2011) Sinan Erten et al. BioData Mining
- The power of protein interaction networks for associating genes with diseases
- (2010) Saket Navlakha et al. BIOINFORMATICS
- Common Variants at 10 Genomic Loci Influence Hemoglobin A1C Levels via Glycemic and Nonglycemic Pathways
- (2010) N. Soranzo et al. DIABETES
- Genetic Variation in IL28B Is Associated With Chronic Hepatitis C and Treatment Failure: A Genome-Wide Association Study
- (2010) Andri Rauch et al. GASTROENTEROLOGY
- Basal ganglia pathology in schizophrenia: dopamine connections and anomalies
- (2010) Emma Perez-Costas et al. JOURNAL OF NEUROCHEMISTRY
- Biological, clinical and population relevance of 95 loci for blood lipids
- (2010) Tanya M. Teslovich et al. NATURE
- Hundreds of variants clustered in genomic loci and biological pathways affect human height
- (2010) Hana Lango Allen et al. NATURE
- Genome-wide association study identifies new HLA class II haplotypes strongly protective against narcolepsy
- (2010) Hyun Hor et al. NATURE GENETICS
- Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index
- (2010) Elizabeth K Speliotes et al. NATURE GENETICS
- Genome-wide association study meta-analysis identifies seven new rheumatoid arthritis risk loci
- (2010) Eli A Stahl et al. NATURE GENETICS
- Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci
- (2010) Andre Franke et al. NATURE GENETICS
- New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk
- (2010) Josée Dupuis et al. NATURE GENETICS
- Entrez Gene: gene-centered information at NCBI
- (2010) D. Maglott et al. NUCLEIC ACIDS RESEARCH
- Role of Mast Cells in Inflammatory Bowel Disease and Inflammation-Associated Colorectal Neoplasia in IL-10-Deficient Mice
- (2010) Maciej Chichlowski et al. PLoS One
- Revealing strengths and weaknesses of methods for gene network inference
- (2010) D. Marbach et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Genome-wide association study reveals genetic risk underlying Parkinson's disease
- (2009) Javier Simón-Sánchez et al. NATURE GENETICS
- Identification of Splenic Reservoir Monocytes and Their Deployment to Inflammatory Sites
- (2009) F. K. Swirski et al. SCIENCE
- Variations in DNA elucidate molecular networks that cause disease
- (2008) Yanqing Chen et al. NATURE
Discover Peeref hubs
Discuss science. Find collaborators. Network.
Join a conversationAdd your recorded webinar
Do you already have a recorded webinar? Grow your audience and get more views by easily listing your recording on Peeref.
Upload Now