Stress hormones promote EGFR inhibitor resistance in NSCLC: Implications for combinations with β-blockers

EGFR Signaling Enhances Aerobic Glycolysis in Triple-Negative Breast Cancer Cells to Promote Tumor Growth and Immune Escape

(2016) S.-O. Lim et al.   CANCER RESEARCH

STK11/LKB1 Deficiency Promotes Neutrophil Recruitment and Proinflammatory Cytokine Production to Suppress T-cell Activity in the Lung Tumor Microenvironment

(2016) S. Koyama et al.   CANCER RESEARCH

Chronic stress in mice remodels lymph vasculature to promote tumour cell dissemination

(2016) Caroline P. Le et al.   Nature Communications

Regulation of nonsmall-cell lung cancer stem cell like cells by neurotransmitters and opioid peptides

(2015) Jheelam Banerjee et al.   INTERNATIONAL JOURNAL OF CANCER

AZD9291 in EGFR Inhibitor–Resistant Non–Small-Cell Lung Cancer

(2015) Pasi A. Jänne et al.   NEW ENGLAND JOURNAL OF MEDICINE

Combined EGFR/MEK Inhibition Prevents the Emergence of Resistance in EGFR-Mutant Lung Cancer

(2015) E. M. Tricker et al.   Cancer Discovery

Obesity Is a Positive Modulator of IL-6R and IL-6 Expression in the Subcutaneous Adipose Tissue: Significance for Metabolic Inflammation

(2015) Sardar Sindhu et al.   PLoS One

IL-6 in diabetes and cardiovascular complications

(2014) Dan Qu et al.   BRITISH JOURNAL OF PHARMACOLOGY

LKB1 Loss Induces Characteristic Patterns of Gene Expression in Human Tumors Associated with NRF2 Activation and Attenuation of PI3K-AKT

(2014) Jacob M. Kaufman et al.   Journal of Thoracic Oncology

Metastasis is regulated via microRNA-200/ZEB1 axis control of tumour cell PD-L1 expression and intratumoral immunosuppression

(2014) Limo Chen et al.   Nature Communications

AZD9291, an Irreversible EGFR TKI, Overcomes T790M-Mediated Resistance to EGFR Inhibitors in Lung Cancer

(2014) D. A. E. Cross et al.   Cancer Discovery

Improved survival outcomes with the incidental use of beta-blockers among patients with non-small-cell lung cancer treated with definitive radiation therapy

(2013) H. M. Wang et al.   ANNALS OF ONCOLOGY

A 12-Gene Set Predicts Survival Benefits from Adjuvant Chemotherapy in Non-Small Cell Lung Cancer Patients

(2013) H. Tang et al.   CLINICAL CANCER RESEARCH

Further data on beta-blockers and cancer risk: observational study and meta-analysis of randomized clinical trials

(2013) Matteo Monami et al.   CURRENT MEDICAL RESEARCH AND OPINION

Phase III Study of Afatinib or Cisplatin Plus Pemetrexed in Patients With Metastatic Lung Adenocarcinoma WithEGFRMutations

(2013) Lecia V. Sequist et al.   JOURNAL OF CLINICAL ONCOLOGY

Use of β-blockers is associated with prostate cancer-specific survival in prostate cancer patients on androgen deprivation therapy

(2012) Helene Hartvedt Grytli et al.   PROSTATE

Reactivation of ERK Signaling Causes Resistance to EGFR Kinase Inhibitors

(2012) Dalia Ercan et al.   Cancer Discovery

5′-AMP-activated protein kinase is inactivated by adrenergic signalling in adult cardiac myocytes

(2011) Yugo Tsuchiya et al.   BIOSCIENCE REPORTS

β-Adrenergic receptors (β-AR) regulate VEGF and IL-6 production by divergent pathways in high β-AR-expressing breast cancer cell lines

(2011) Kelley S. Madden et al.   BREAST CANCER RESEARCH AND TREATMENT

Social Stress Promotes and  -Aminobutyric Acid Inhibits Tumor Growth in Mouse Models of Non-Small Cell Lung Cancer

(2011) H. A. N. Al-Wadei et al.   Cancer Prevention Research

Beta Blockers and Breast Cancer Mortality: A Population- Based Study

(2011) Thomas I. Barron et al.   JOURNAL OF CLINICAL ONCOLOGY

Phase III Trial of Vandetanib Compared With Erlotinib in Patients With Previously Treated Advanced Non–Small-Cell Lung Cancer

(2011) Ronald B. Natale et al.   JOURNAL OF CLINICAL ONCOLOGY

Effects of adrenaline in human colon adenocarcinoma HT-29 cells

(2011) Helen P.S. Wong et al.   LIFE SCIENCES

A stress response pathway regulates DNA damage through β2-adrenoreceptors and β-arrestin-1

(2011) Makoto R. Hara et al.   NATURE

The BATTLE Trial: Personalizing Therapy for Lung Cancer

(2011) Edward S. Kim et al.   Cancer Discovery

The Sympathetic Nervous System Induces a Metastatic Switch in Primary Breast Cancer

(2010) E. K. Sloan et al.   CANCER RESEARCH

Proteomic Profiling Identifies Pathways Dysregulated in Non-small Cell Lung Cancer and an Inverse Association of AMPK and Adhesion Pathways with Recurrence

(2010) Meera Nanjundan et al.   Journal of Thoracic Oncology

Computational identification of gene-social environment interaction at the human IL6 locus

(2010) S. W. Cole et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

TGF-  IL-6 axis mediates selective and adaptive mechanisms of resistance to molecular targeted therapy in lung cancer

(2010) Z. Yao et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Adrenaline induces chemoresistance in HT-29 colon adenocarcinoma cells

(2009) Herui Yao et al.   CANCER GENETICS AND CYTOGENETICS

Reciprocal Regulation of c-Src and STAT3 in Non-Small Cell Lung Cancer

(2009) L. A. Byers et al.   CLINICAL CANCER RESEARCH

LKB1 and Mammalian Target of Rapamycin As Predictive Factors for the Anticancer Efficacy of Metformin

(2009) Regan M. Memmott et al.   JOURNAL OF CLINICAL ONCOLOGY

Psychological distress and cancer mortality

(2009) Mark Hamer et al.   JOURNAL OF PSYCHOSOMATIC RESEARCH

Oncogenic B-RAF Negatively Regulates the Tumor Suppressor LKB1 to Promote Melanoma Cell Proliferation

(2009) Bin Zheng et al.   MOLECULAR CELL

Mutations in the LKB1 tumour suppressor are frequently detected in tumours from Caucasian but not Asian lung cancer patients

(2008) J P Koivunen et al.   BRITISH JOURNAL OF CANCER

Mechanisms of Acquired Resistance to Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitors in Non-Small Cell Lung Cancer

(2008) J. A. Engelman et al.   CLINICAL CANCER RESEARCH

Epac and Phospholipase Cϵ Regulate Ca2+Release in the Heart by Activation of Protein Kinase Cϵ and Calcium-Calmodulin Kinase II

(2008) Emily A. Oestreich et al.   JOURNAL OF BIOLOGICAL CHEMISTRY